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Specialty: Neurology
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Total 1309 results found since Jan 2013.

Effects of Repetitive Peripheral Sensory Stimulation in the Subacute and Chronic Phases After Stroke: Study Protocol for a Pilot Randomized Trial
DiscussionThe results of this study are relevant to inform future clinical trials to tailor RPSS to patients more likely to benefit from this intervention.Trial RegistrationNCT03956407.
Source: Frontiers in Neurology - February 16, 2022 Category: Neurology Source Type: research

Leveraging Factors of Self-Efficacy and Motivation to Optimize Stroke Recovery
The International Classification of Functioning, Disability and Health framework recognizes that an individual's functioning post-stroke reflects an interaction between their health condition and contextual factors encompassing personal and environmental factors. Personal factors significantly impact rehabilitation outcomes as they determine how an individual evaluates their situation and copes with their condition in daily life. A key personal factor is self-efficacy—an individual's belief in their capacity to achieve certain outcomes. Self-efficacy influences an individual's motivational state to execute behaviors nece...
Source: Frontiers in Neurology - February 24, 2022 Category: Neurology Source Type: research

Bridging the Transient Intraluminal Stroke Preclinical Model to Clinical Practice: From Improved Surgical Procedures to a Workflow of Functional Tests
Acute ischemic stroke (AIS) remains a leading cause of mortality, despite significant advances in therapy (endovascular thrombectomy). Failure in developing novel effective therapies is associated with unsuccessful translation from preclinical studies to clinical practice, associated to inconsistent and highly variable infarct areas and lack of relevant post-stroke functional evaluation in preclinical research. To outreach these limitations, we optimized the intraluminal transient middle cerebral occlusion, a widely used mouse stroke model, in two key parameters, selection of appropriate occlusion filaments and time of occ...
Source: Frontiers in Neurology - March 11, 2022 Category: Neurology Source Type: research

Design and implementation of a Stroke Rehabilitation Registry for the systematic assessment of processes and outcomes and the development of data-driven prediction models: The STRATEGY study protocol
ConclusionsThis study will test the feasibility of a stroke rehabilitation registry in the Italian health context and provide a systematic assessment of processes and outcomes for quality assessment and benchmarking. By the development of data-driven prediction models in stroke rehabilitation, this study will pave the way for the development of decision support tools for patient-oriented therapy planning and rehabilitation outcomes maximization.Clinical tial registrationThe registration on ClinicalTrials.gov is ongoing and under review. The identification number will be provided when the review process will be completed.
Source: Frontiers in Neurology - October 10, 2022 Category: Neurology Source Type: research

Moderate-intensity cardiovascular exercise performed before motor practice attenuates offline implicit motor learning in stroke survivors but not age-matched neurotypical adults
Exp Brain Res. 2023 Jul 3. doi: 10.1007/s00221-023-06659-w. Online ahead of print.ABSTRACTThe acute impact of cardiovascular exercise on implicit motor learning of stroke survivors is still unknown. We investigated the effects of cardiovascular exercise on implicit motor learning of mild-moderately impaired chronic stroke survivors and neurotypical adults. We addressed whether exercise priming effects are time-dependent (e.g., exercise before or after practice) in the encoding (acquisition) and recall (retention) phases. Forty-five stroke survivors and 45 age-matched neurotypical adults were randomized into three sub-group...
Source: Brain Research - July 3, 2023 Category: Neurology Authors: Giordano Marcio Gatinho Bonuzzi Flavio Henrique Bastos Nicolas Schweighofer Eric Wade Carolee Joyce Winstein Camila Torriani-Pasin Source Type: research

Hippocampal Volume and Memory Performance in Children With Perinatal Stroke
Conclusions: These findings support the view that, in the developing brain, the left and right hippocampi preferentially support verbal and nonverbal memory respectively, a consistent finding in the adult literature but a subject of debate in the pediatric literature. This is the first work to report that children with focal brain injury incurred from perinatal stroke have volume reduction in the hippocampus and impairments in certain aspects of declarative memory.
Source: Pediatric Neurology - November 4, 2013 Category: Neurology Authors: Jeffrey J. Gold, Doris A. Trauner Tags: Original Articles Source Type: research

Learning the spatial features of a locomotor task is slowed after stroke
The capacity for humans to learn a new walking pattern has been explored with a split-belt treadmill during single sessions of adaptation, but the split-belt treadmill can also be used to study longer-term motor learning. Although the literature provides some information about motor learning after stroke, existing studies have primarily involved the upper extremity and the results are mixed. The purpose of this study was to characterize learning of a novel locomotor task in stroke survivors. We hypothesized that the presence of neurological dysfunction from stroke would result in slower learning of a locomotor task and dec...
Source: Journal of Neurophysiology - July 15, 2014 Category: Neurology Authors: Tyrell, C. M., Helm, E., Reisman, D. S. Tags: Articles Source Type: research

Spatial cognitive rehabilitation and motor recovery after stroke
Purpose of review: Stroke rehabilitation needs to take major steps forward to reduce functional disability for survivors. In this article, we suggest that spatial retraining might greatly increase the efficiency and efficacy of motor rehabilitation, directly addressing the burden and cost of paralysis after stroke. Recent findings: Combining motor and cognitive treatment may be practical, as well as addressing the needs after moderate-to-severe stroke. Spatial neglect could suppress motor recovery and reduce motor learning, even when patients receive appropriate rehabilitation to build strength, dexterity, and endurance. S...
Source: Current Opinion in Neurology - November 7, 2014 Category: Neurology Tags: DEGENERATIVE AND COGNITIVE DISEASES: Edited by Gabriella Bottini Source Type: research

Endovascular Stroke Therapy Results Improve over Time: The ‘Learning Curve' at a New Comprehensive Stoke Center
Conclusions: At a new community-based CSC, improved outcome occurred from year 1 to year 2, and trends towards decreased mortality, fewer complications, and improved revascularization were observed. Furthermore, the data shows that improvement in NIHSS score after EST is associated with decreased mortality following stroke in this setting, implying a net benefit.Cerebrovasc Dis Extra 2014;4:235-242
Source: Cerebrovascular Diseases Extra - January 13, 2015 Category: Neurology Source Type: research

Cognitive state following mild stroke: A matter of hippocampal mean diffusivity
This article is protected by copyright. All rights reserved.
Source: Hippocampus - July 27, 2015 Category: Neurology Authors: Efrat Kliper, Einor Ben Assayag, Amos D. Korczyn, Eitan Auriel, Ludmila Shopin, Hen Hallevi, Shani Shenhar‐Tsarfaty, Anat Mike, Moran Artzi, Ilana Klovatch, Natan M. Bornstein, Dafna Ben Bashat Tags: Research Article Source Type: research

Identification of the factors conditioning times and indicators of quality in the intrahospital care of acute stroke.
CONCLUSIONS: Knowledge of the current situation of the times and quality indicators and their determinants are essential to provide the motivation to start an initiative to improve the quality of care in patients with acute stroke. PMID: 26860720 [PubMed - in process]
Source: Revista de Neurologia - February 12, 2016 Category: Neurology Authors: Palazon-Cabanes B, Lopez-Picazo Ferrer JJ, Morales-Ortiz A, Tomas-Garcia N Tags: Rev Neurol Source Type: research

Paired associative stimulation modulates corticomotor excitability in chronic stroke: A preliminary investigation.
CONCLUSION: These results provide preliminary evidence for the potential of PAS to increase corticomotor excitability that could favorably impact motor skill performance in chronic individuals post-stroke and are an important first step for future studies investigating the clinical application and behavioral relevance of PAS interventions in post stroke patient populations. PMID: 29526858 [PubMed - in process]
Source: Restorative Neurology and Neuroscience - March 13, 2018 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Management of Stroke in the Neurocritical Care Unit
This article provides updated information regarding the diagnosis and treatment (specifically critical care management) of acute ischemic stroke. This article also discusses the increased use of thrombolysis and thrombectomy in clinical practice. RECENT FINDINGS Stroke is the leading cause of disability in the United States. A significant proportion of patients with acute ischemic stroke require critical care management. Much has changed in the early evaluation and treatment of patients presenting with acute ischemic stroke. The introduction of embolectomy in large vessel occlusions for up to 24 hours post–symptom ons...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2018 Category: Neurology Tags: REVIEW ARTICLES Source Type: research