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Source: Hypertension
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Total 263 results found since Jan 2013.
Abstract P378: Current Progress of Antihypertensive Medication Use According to Healthy People 2020 Goals Among Adults With Hypertension- the National Health Interview Survey 2014-2015 Session Title: Blood Pressure Control and Adherence to Treatment
Conclusion: To control hypertension, most patients require antihypertensive medications to achieve control. Understanding disparities in antihypertensive medication utilization is needed for all population to achieve Healthy People 2020 targets by the end of the decade.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Jing Fang, Carma Ayala, Fleetwood Loustalot Tags: Poster Abstract Presentations Source Type: research
Abstract P392: Autonomic Reflexes Mask the Hemodynamic Effects of Continuous Positive Airway Pressure Session Title: Neurogenic Mechanisms
Continuous positive airway pressure (CPAP) improves cardiac function and blood pressure (BP) in patients with sleep-breathing disorders by reducing increased sympathetic tone. The direct hemodynamic effects of increased intrathoracic pressure with CPAP, however, are not known and are likely masked by baroreflex buffering. To determine the acute hemodynamic effects of CPAP in the absence of autonomic modulation, we applied 5 levels of CPAP (0, 4, 8, 12 and 16 cm H2O, each for 2 min) to 7 healthy normotensive (NTN, 33±3 years, BMI 29±3, 4 females) and 12 hypertensive subjects (HTN, 50±2 years, BMI 30±2, 8 females) before...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Luis E Okamoto, Alfredo Gamboa, Jorge E Celedonio, Andre Diedrich, Sachin Y Paranjape, Italo Biaggioni Tags: Poster Abstract Presentations Source Type: research
Abstract P396: The Stroke Belt: Forged in the Heat of the Buckle? A Hypothesis Session Title: Epidemiology
The “stroke belt”(SB) in the SE USA has significantly higher stroke rates in whites (W) and African Americans (AA). HTN is the major driving force. The “Buckle” (B) of the SB, with even higher rates, lies along the costal “low country” plains of the Carolinas. Being born in the B is a powerful exposure that increases risk. Forty percent of all US slaves came thru, slaved and many died in the B of the SB. While reading the scholarly review “Slavery, Disease and Suffering in the Southern Low Country”, by Dr. Peter McCandless, (Cambridge U Press, 2011) I was stuck with the effect of the hot, humid weather with...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Clarence Grim Tags: Poster Abstract Presentations Source Type: research
Abstract P400: Relative Contributions of Systolic and Diastolic Blood Pressure to Adverse Cardiovascular Outcomes in an Outpatient Cohort of 1.3 Million Adults Session Title: Epidemiology
We examined the impact of systolic and diastolic pressures in multivariable survival analysis controlling for age, sex, race, and comorbidities using two different approaches. We first used the burden of systolic (SBP>=140) and diastolic (DBP>=90) hypertension as predictors. Both systolic burden (hazard ratio [HR] 1.17 for z-score, 95% CI 1.16 to 1.18, P78). Again, both SBP (HR 1.39 for z-score, 95% CI 1.37 to 1.41, P
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Alexander C Flint, Carol Conell, Xiushui Ren, Nader Banki, Sheila L Chan, Vivek A Rao, Ron B Melles, Deepak L Bhatt Tags: Poster Abstract Presentations Source Type: research
Abstract P401: The Progress of Carotid Atherosclerosis is Associated With Incident Stroke and Coronary Heart Disease: The Suita Study Session Title: Epidemiology
Conclusions: The novel finding of this study is that CIMT-plaque progression could be a good predictor of new-onset CVD in a general population.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Yoshihiro Kokubo, Makoto Watanabe, Aya Higashiyama, Yoko M Nakao, Fumiaki Nakamura, Yoshihiro Miyamoto Tags: Poster Abstract Presentations Source Type: research
Abstract P421: The Effects of Dual Angiotensin Receptor and Neprilysin Inhibitor on Organoprotection in Experimental Model of Chronic Heart Failure Session Title: Renin-Angiotensin System
The cardiac effects of dual angiotensin receptor and neprilysin inhibitor (LCZ696) as a novel therapeutic approach for inhibition of renin-angiotensin system was assessed in volume overload-induced chronic heart failure (CHF) in hypertensive Ren2 transgenic rats (TGR) with aorto-caval fistula (ACF) and compared with valsartan (VAL). CHF model was induced by ACF in male TGR at 8 weeks of age. After 5 weeks of ACF induction, LCZ696 was administered in standard dosing at 68 mg/kg/day and VAL at 31 mg/kg/day for next 15 weeks to assess the effect on mortality. In second series, 12 weeks after ACF, the animals were anaesthetize...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Libor Kopkan, Lenka Hoskova, Voȷtech Melenovsky, Zuzana Huskova, Ludek Cervenka Tags: Poster Abstract Presentations Source Type: research
Abstract P201: Prevalence of Metabolic Syndrome in Hypertensive Patients Session Title: Onsite Poster Competition I With Reception
This study was done to find out the prevalence of metabolic syndrome among newly diagnosed hypertensive patients in a tertiary care hospital of northern India, Guru Nanak Dev hospital, attached to Government Medical College, Amritsar, India.Methods: It is a hospital based cross sectional study involving one hundred newly diagnosed subjects with hypertension above the age 20 years. High blood pressure was defined according to Joint National committe-7 (JNC-7) guidelines, taking systolic BP> 140 and diastolic BP>90 as hypertension. Exclusion criteria included secondary hypertension, secondary cause of obesity, pregnancy, acu...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Nirankar Singh Neki, Jaswinder Singh Tags: Poster Abstract Presentations Source Type: research
Abstract P242: Nicotinic Acetylcholine Receptor Subunit {alpha}7 is Protective Against Angiotensin II-induced Aneurysm and Hypertension Session Title: Onsite Poster Competition I With Reception
We report for the first time that the α7 nAChR-/- deficient mouse serves as a novel model of hypertension and aneurysm formation. Seven month old male WT and α7 nAChR-/- mice weighing 28-33g were infused with low dose Ang II (350 ng/kg/min) or high dose (700 ng/kg/min) or vehicle for 15 days using mini-osmotic pumps (Alzet, model 2004) implanted subcutaneously. Blood pressure (BP) was recorded on day 0,3,7,10 and 14. Mice were euthanized on day 15. Heart and body weights were measured, histological analysis was performed on the aortas and immune profile of peripheral blood was analyzed by flow cytometry. High dose Ang II...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Nayaab S Khan, Spyros Mavropoulos, Kaie Ojamaa Tags: Poster Abstract Presentations Source Type: research
Abstract P253: Relation Between Microvascular Function and Large Artery Stiffness in African American Diabetic Patients Session Title: Onsite Poster Competition I With Reception
Conclusions: Among African Americans with diabetes, subclinical microvascular dysfunction is significantly correlated to large artery stiffness and possibly to glycemic control. Further study is needed to clarify mediating factors of these relationships.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Ajibola M Adedayo, Ayobami Eluwole, Fasika Tedla, Arye Kremer, Nicole Mastrogiovanni, Mohammed Afzal, Carl Rosenberg, Paul Dreizen, John LaRosa, Mohamed Boutjdir, MaryAnn Banerji, Clinton Brown, Moro Salifu, Ahmed Bakillah, Jason Lazar Tags: Poster Abstract Presentations Source Type: research
Abstract P257: Investigating Angiotensin II Infusion as a Model of Superimposed Preeclampsia in Pregnant Stroke Prone Spontaneously Hypertensive Rats Session Title: Onsite Poster Competition II
Background: Hypertensive disorders of pregnancy are a leading cause of maternal mortality worldwide. Chronic hypertension with superimposed preeclampsia is becoming more prevalent in modern society. Animal models are vital for understanding this condition. Our aim was to induce a preeclamptic phenotype in pregnant stroke prone spontaneously hypertensive (SHRSP) rats by angiotensin II (AngII) infusion.Methods: AngII, at a dose of 500ng/kg/min or 1000ng/kg/min, was administered by minipump in pregnant SHRSP rats from gestational day (GD)10. Cardiovascular and renal changes were monitored using radiotelemetry, echocardiograph...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Hannah L Morgan, Elaine Butler, Elisabeth Beattie, Martin W McBride, Delyth Graham Tags: Poster Abstract Presentations Source Type: research
Abstract P279: Mapping of Chromosome 2 Differentially Expressed Aortic Genes Linked to Vascular Inflammation Using Congenic Rats Fed a High-salt Diet Session Title: Onsite Poster Competition II
Background: Three congenic rat strains (SB2a, SB2b and SB2e) were created by chromosome (Chr) 2 fragment introgression from normotensive Brown Norway (BN) rats into hypertensive Dahl salt sensitive (SS) background. SB2a and SB2b rats fed a normal-salt diet presented reduced blood pressure (BP) and inflammation when compared to SS rats. We hypothesized that BN-Chr2 contains antihypertensive and anti-inflammatory genes that could prevent high-salt diet (HSD)-induced BP elevation and vascular injury in SB2a and SB2b rats. These genes will be identified using microRNA (miRNA) and total RNA expression profiling analysis in aort...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Olga Berillo, Sofiane Ouerd, Ku-Geng Huo, Chantal Richer, Daniel Sinnett, Anne E Kwitek, Pierre Paradis, Ernesto L Schiffrin Tags: Poster Abstract Presentations Source Type: research
Abstract P304: Motivia(R), a Cardiovascular Disease Prevention Program, Decreases Hospitalization Length in Patients With High Risk for Developing Cardiovascular Event. Retrospective Analysis From 2010-2015 Session Title: Pregnancy and Preeclampsia and Developmental Programming of Cardiovascular Disease
Conclusions: Motivia® program, based on intensive treatment using TPA determination may benefit patients and health insurance by decreasing hospitality length.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Hernan A Perez, Natalia Jorgensen, Santiago Torales, Andres Chianalino, Luis J Armando Tags: Poster Abstract Presentations Source Type: research
Abstract P334: Persistent Adrenomedullin Derivative Inhibits Development of Hypertension Session Title: Salt and Hypertension
Human adrenomedullin (hAM) consists of a 52 amino acid peptide that is amidated and has a disulfide bond. The bioactive peptide hAM has a variety of physiological functions, such as vasodilatation, hormone secretion, neurotransmission, embryogenesis, wound healing and immunoregulation. hAM has shown several therapeutic effects in experimental models of various diseases, including ischemic heart disease, inflammatory bowel disease, stroke and retinochoroidal disease. However, these therapies required continuous administration of hAM as the half-life of native hAM is quite short in blood. To resolve these issues, the aim of ...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Sayaka Nagata, Motoo Yamasaki, Kazuo Kitamura Tags: Poster Abstract Presentations Source Type: research
Abstract P346: Diurnal Variation of Serum Uric Acid Levels and Corresponding Variations of Oxidative Stress Makers in Patients With Hypertension and Stable Coronary Artery Disease Session Title: Inflammation, Immunity and Cytokines, Endothelial Factors, and Oxidative Stress
Discussion: Serum UA levels showed diurnal variation even in patients with hypertension and CAD. Considering the fact that oxidative stress makers showed corresponding diurnal variations, diurnal variation of serum UA level may play a role in the pathogenesis of CAD.
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Megumi Shimizu, Takatoshi Kasai, Shoichiro Yatsu, Azusa Murata, Hiroki Matsumoto, Jun Shitara, Takao Kato, Shoko Suda, Masaru Hiki, Ryo Naito, Kazunori Shimada, Hiroyuki Daida Tags: Poster Abstract Presentations Source Type: research
Abstract P351: Cornell Product in Electrocardiogram is More Strongly Related to LV Regional Wall Motion Than Sokolow-Lyon Voltage Session Title: Cardiac Hypertrophy and Dysfunction and Coronary Artery Disease and Hypertension
Backgrounds: Left ventricular hypertrophy (LVH) evaluated by Cornell product in electrocardiogram predicted future stroke events greater than LVH by Sokolow-Lyon voltage. Therefore, we evaluated whether Cornell product was related to regional myocardial wall motion greater than Sokolow-Lyon voltage.Methods: We enrolled 288 hypertensive patients who were performed echocardiography for evaluating target organ damage. Cornell product was calculated as follows; R in aVL lead + S in V3 lead (0.6 mV added in female)хQRS duration; Sokolow-Lyon voltage, R in V5 lead + S in lead V1. We evaluated left ventricular mass index (LVMI),...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Joji Ishikawa, Yuko Yamanaka, Shintaro Watanabe, Kazumasa Harada Tags: Poster Abstract Presentations Source Type: research
