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Source: Hypertension
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Total 263 results found since Jan 2013.
Masked Hypertension and Cardiovascular Disease Events in a Prospective Cohort of Blacks: The Jackson Heart Study Masked Hypertension
Masked hypertension, defined as nonelevated clinic blood pressure (BP) with elevated out-of-clinic BP, has been associated with increased cardiovascular disease (CVD) risk in Europeans and Asians. Few data are available on masked hypertension and CVD and mortality risk among blacks. We analyzed data from the Jackson Heart Study, a prospective cohort study of blacks. Analyses included participants with clinic-measured systolic/diastolic BP <140/90 mm Hg who completed ambulatory BP monitoring after the baseline examination in 2000 to 2004 (n=738). Masked daytime (10:00 am–8:00 pm) hypertension was defined as mean am...
Source: Hypertension - July 12, 2016 Category: Cardiology Authors: Booth, J. N., Diaz, K. M., Seals, S. R., Sims, M., Ravenell, J., Muntner, P., Shimbo, D. Tags: Cardiovascular Disease, Epidemiology, Hypertension Masked Hypertension Source Type: research
The Association Between Antihypertensive Medication Nonadherence and Visit-to-Visit Variability of Blood Pressure: Findings From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial Epidemiology/Population
In conclusion, improving medication adherence may lower VVV of BP. However, VVV of BP is associated with cardiovascular outcomes independent of medication adherence.
Source: Hypertension - June 7, 2016 Category: Cardiology Authors: Kronish, I. M., Lynch, A. I., Oparil, S., Whittle, J., Davis, B. R., Simpson, L. M., Krousel-Wood, M., Cushman, W. C., Chang, T. I., Muntner, P. Tags: Hypertension Epidemiology/Population Source Type: research
Independent and Joint Effect of Brachial-Ankle Pulse Wave Velocity and Blood Pressure Control on Incident Stroke in Hypertensive Adults Epidemiology/Population
This report included 3310 hypertensive adults, a subset of the China Stroke Primary Prevention Trial (CSPPT) with baseline measurements for baPWV. During a median follow-up of 4.5 years, 111 participants developed first stroke. The risk of stroke was higher among participants with baPWV in the highest quartile than among those in the lower quartiles (6.3% versus 2.4%; hazard ratio, 1.66; 95% confidence interval, 1.06–2.60). Similarly, the participants with inadequate hypertension control had a higher risk of stroke than those with adequate control (5.1% versus 1.8%; hazard ratio, 2.32; 95% confidence interval, 1.49&n...
Source: Hypertension - June 7, 2016 Category: Cardiology Authors: Song, Y., Xu, B., Xu, R., Tung, R., Frank, E., Tromble, W., Fu, T., Zhang, W., Yu, T., Zhang, C., Fan, F., Zhang, Y., Li, J., Bao, H., Cheng, X., Qin, X., Tang, G., Chen, Y., Yang, T., Sun, N., Li, X., Zhao, L., Hou, F. F., Ge, J., Dong, Q., Wang, B., Xu, Tags: Hypertension, Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research
Morning and Evening Home Blood Pressure and Risks of Incident Stroke and Coronary Artery Disease in the Japanese General Practice Population: The Japan Morning Surge-Home Blood Pressure Study Epidemiology/Population
Our aim is to determine the optimal time schedule for home blood pressure (BP) monitoring that best predicts stroke and coronary artery disease in general practice. The Japan Morning Surge-Home Blood Pressure (J-HOP) study is a nationwide practice-based study that included 4310 Japanese with a history of or risk factors for cardiovascular disease, or both (mean age, 65 years; 79% used antihypertensive medication). Home BP measures were taken twice daily (morning and evening) over 14 days at baseline. During a mean follow-up of 4 years (16 929 person-years), 74 stroke and 77 coronary artery disease events occurred. Morning ...
Source: Hypertension - June 7, 2016 Category: Cardiology Authors: Hoshide, S., Yano, Y., Haimoto, H., Yamagiwa, K., Uchiba, K., Nagasaka, S., Matsui, Y., Nakamura, A., Fukutomi, M., Eguchi, K., Ishikawa, J., Kario, K., on behalf of the J-HOP Study Group Tags: Hypertension Epidemiology/Population Source Type: research
Mid- to Late-Life Trajectories of Blood Pressure and the Risk of Stroke: The Rotterdam Study Epidemiology/Population
Hypertension is a major modifiable risk factor for stroke. Associations of blood pressure with incident stroke are mostly based on single or average blood pressure levels. However, this approach does not take into account long-term trajectories of blood pressure, which can vary considerably in the elderly. Within the population-based Rotterdam Study, we examined trajectories of systolic blood pressure in 6745 participants (60.0% women) over an age-range from 55 to 106 years and jointly modeled their risk of stroke and competing causes of death using joint latent class mixed modeling. Four trajectories were identified. Clas...
Source: Hypertension - May 10, 2016 Category: Cardiology Authors: Portegies, M. L. P., Mirza, S. S., Verlinden, V. J. A., Hofman, A., Koudstaal, P. J., Swanson, S. A., Ikram, M. A. Tags: Epidemiology, High Blood Pressure, Mortality/Survival, Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research
Association Between Protein Intake and Mortality in Hypertensive Patients Without Chronic Kidney Disease in the OLD-HTA Cohort Epidemiology/Population
The objective of this study was to test the prognostic value of protein intake assessed by 24-hour urinary urea in a cohort of hypertensive patients with preserved renal function. A total of 1128 hypertensive patients were followed according to tertile of protein intake adjusted for ideal body weight: <0.70, 0.70 to 0.93, and >0.93 g/kg. Baseline characteristics (mean±standard deviation) were age 45.1±13.2 years, systolic/diastolic blood pressure 185±32/107±20 mm Hg, and estimated glomerular filtration rate 82±32 mL/min. After 10 years of follow-up, 289 deaths occurred, 202 of which...
Source: Hypertension - May 10, 2016 Category: Cardiology Authors: Courand, P.-Y., Lesiuk, C., Milon, H., Defforges, A., Fouque, D., Harbaoui, B., Lantelme, P. Tags: Diet and Nutrition, Epidemiology, Hypertension Epidemiology/Population Source Type: research
Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study Epidemiology/Population
Elevated blood pressure in midlife contributes significantly to the risk of cardiovascular disease. However, patterns of blood pressure increase may differ among individuals and may result in differential risk. Our goal was to examine the contribution of longitudinal patterns of blood pressure change to incidence of heart failure, coronary heart disease, stroke, and cardiovascular disease mortality. Latent class growth models were used to identify patterns of change in blood pressure across 4 clinical examinations (1987–1998) among 9845 Atherosclerosis Risk in Communities (ARIC) cohort participants (mean age, 53.7 [S...
Source: Hypertension - May 10, 2016 Category: Cardiology Authors: Petruski-Ivleva, N., Viera, A. J., Shimbo, D., Muntner, P., Avery, C. L., Schneider, A. L. C., Couper, D., Kucharska-Newton, A. Tags: Cardiovascular Disease, Risk Factors, Hypertension Epidemiology/Population Source Type: research
Selective Heart Rate Reduction With Ivabradine Increases Central Blood Pressure in Stable Coronary Artery Disease Clinical Trials
In conclusion, the decrease in HR with ivabradine was associated with an increase in central systolic pressure, which may have antagonized possible benefits of HR lowering in coronary artery disease patients.
Clinical Trials—URL:
http://www.clinicaltrials.gov. Unique identifier NCT01039389.
Source: Hypertension - May 10, 2016 Category: Cardiology Authors: Rimoldi, S. F., Messerli, F. H., Cerny, D., Gloekler, S., Traupe, T., Laurent, S., Seiler, C. Tags: Hemodynamics, Hypertension, Coronary Artery Disease Clinical Trials Source Type: research
Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events Flow-Mediated Vasodilation and Cardiovascular Events
Measurement of nitroglycerine-induced vasodilation has been performed to differentiate endothelium-dependent vasodilation from endothelium-independent vasodilation as a control test for flow-mediated vasodilation (FMD). Recently, nitroglycerine-induced vasodilation per se has been reported to be a useful marker of the grade of atherosclerosis. The present study aimed to evaluate the prognostic value of FMD combined with nitroglycerine-induced vasodilation for future cardiovascular events. We measured FMD and nitroglycerine-induced vasodilation in 402 subjects, including patients with cardiovascular diseases. During a media...
Source: Hypertension - April 12, 2016 Category: Cardiology Authors: Kajikawa, M., Maruhashi, T., Hida, E., Iwamoto, Y., Matsumoto, T., Iwamoto, A., Oda, N., Kishimoto, S., Matsui, S., Hidaka, T., Kihara, Y., Chayama, K., Goto, C., Aibara, Y., Nakashima, A., Noma, K., Higashi, Y. Tags: Quality and Outcomes, Atherosclerosis Flow-Mediated Vasodilation and Cardiovascular Events Source Type: research
Persistent Maternal Cardiac Dysfunction After Preeclampsia Identifies Patients at Risk for Recurrent Preeclampsia Preeclampsia
The purpose of our study was to assess cardiac function in nonpregnant women with previous early preeclampsia before a second pregnancy to highlight the cardiovascular pattern, which may take a risk for recurrent preeclampsia. Seventy-five normotensive patients with previous preeclampsia and 147 controls with a previous uneventful pregnancy were enrolled in a case-control study and submitted to echocardiographic examination in the nonpregnant state 12 to 18 months after the first delivery. All patients included in the study had pregnancy within 24 months from the echocardiographic examination and were followed until term. ...
Source: Hypertension - March 9, 2016 Category: Cardiology Authors: Valensise, H., Lo Presti, D., Gagliardi, G., Tiralongo, G. M., Pisani, I., Novelli, G. P., Vasapollo, B. Tags: Preeclampsia, Echocardiography, Complications Source Type: research
Maternal Cardiovascular Function in Normal Pregnancy: Evidence of Maladaptation to Chronic Volume Overload Pregnancy and Hypertension
The aim of this study was to investigate cardiac functional status in pregnancy using a comprehensive approach taking into account the simultaneous changes in loading and geometry, as well as maternal age and anthropometric indices. This was a prospective cross-sectional study of 559 nulliparous pregnant women assessed at 4 time points during pregnancy and at 1 year postpartum. All women underwent conventional echocardiography and tissue Doppler velocities and strain rate analysis at multiple cardiac sites. Mean arterial pressure and total vascular resistance index significantly decreased (both P<0.001) during the first...
Source: Hypertension - March 9, 2016 Category: Cardiology Authors: Melchiorre, K., Sharma, R., Khalil, A., Thilaganathan, B. Tags: Heart Failure, Remodeling, Preeclampsia, Echocardiography Pregnancy and Hypertension Source Type: research
Medication Adherence and the Risk of Cardiovascular Mortality and Hospitalization Among Patients With Newly Prescribed Antihypertensive Medications Epidemiology/Population
This study evaluated the effect of antihypertensive medication adherence on specific cardiovascular disease mortality (ischemic heart disease [IHD], cerebral hemorrhage, and cerebral infarction). Our study used data from a 3% sample cohort that was randomly extracted from enrollees of Korean National Health Insurance. Study subjects were aged ≥20 years, were diagnosed with hypertension, and started newly prescribed antihypertensive medication in 2003 to 2004. Adherence to antihypertensive medication was estimated as the cumulative medication adherence. Subjects were divided into good (cumulative medication adherence, &g...
Source: Hypertension - February 10, 2016 Category: Cardiology Authors: Kim, S., Shin, D. W., Yun, J. M., Hwang, Y., Park, S. K., Ko, Y.-J., Cho, B. Tags: Cardiovascular Disease, Primary Prevention, Compliance/Adherence, Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research
Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study Epidemiology/Population
In conclusion, aortic stiffness was associated with cognitive function and markers of subclinical brain injury in young to middle-aged adults. Prospective studies are needed to examine whether aortic stiffening in young adulthood is associated with vascular cognitive impairment later in life.
Source: Hypertension - February 10, 2016 Category: Cardiology Authors: Pase, M. P., Himali, J. J., Mitchell, G. F., Beiser, A., Maillard, P., Tsao, C., Larson, M. G., DeCarli, C., Vasan, R. S., Seshadri, S. Tags: Aging, Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment Epidemiology/Population Source Type: research
Evidence to Maintain the Systolic Blood Pressure Treatment Threshold at 140 mm Hg for Stroke Prevention: The Northern Manhattan Study Epidemiology/Population
In 2014, the Eighth Joint National Committee revised the target maximum systolic blood pressure (SBP) from 140 to 150 mm Hg in patients aged ≥60 years without diabetes mellitus or chronic kidney disease. The evidence from cohort studies supporting this change was sparse, particularly among US minority populations. In the Northern Manhattan Study, 1750 participants aged ≥60 years and free of stroke, diabetes mellitus, and chronic kidney disease had SBP measured at baseline and were annually followed up for incident stroke. Mean age at baseline was 72±8 years, 63% were women, 48% Hispanic, 25% non-Hispanic white...
Source: Hypertension - February 10, 2016 Category: Cardiology Authors: Dong, C., Della-Morte, D., Rundek, T., Wright, C. B., Elkind, M. S. V., Sacco, R. L. Tags: Epidemiology Epidemiology/Population Source Type: research
Allopurinol and Cardiovascular Outcomes in Adults With Hypertension Epidemiology/Population
Allopurinol lowers blood pressure in adolescents and has other vasoprotective effects. Whether similar benefits occur in older individuals remains unclear. We hypothesized that allopurinol is associated with improved cardiovascular outcomes in older adults with hypertension. Data from the United Kingdom Clinical Research Practice Datalink were used. Multivariate Cox-proportional hazard models were applied to estimate hazard ratios for stroke and cardiac events (defined as myocardial infarction or acute coronary syndrome) associated with allopurinol use over a 10-year period in adults aged >65 years with hypertension. A ...
Source: Hypertension - February 10, 2016 Category: Cardiology Authors: MacIsaac, R. L., Salatzki, J., Higgins, P., Walters, M. R., Padmanabhan, S., Dominiczak, A. F., Touyz, R. M., Dawson, J. Tags: Cerebrovascular Disease/Stroke Epidemiology/Population Source Type: research
