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Condition: Pregnancy
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Total 1466 results found since Jan 2013.
Pregnancy-associated stroke and the recurrence of stroke and other complications in subsequent pregnancies: Population-based retrospective cohort study
CONCLUSIONS: Subsequent pregnancies of women with a history of PAS are more often complicated with hypertensive disorders of pregnancy and any diabetes during pregnancy. PAS recurrence risk is considerable.PMID:37088716 | DOI:10.1111/1471-0528.17503
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 23, 2023 Category: OBGYN Authors: Liisa Verho Minna Tikkanen Outi Äyräs Karoliina Aarnio Kirsi Rantanen Aino Korhonen Anna Richardt Hannele Laivuori Mika Gissler Petra Ij äs Source Type: research
Extreme preterm neonate with fetal warfarin syndrome
A 25+3 week gestation male infant weighing 493 g was delivered via caesarean section for intrauterine growth restriction and abnormal Dopplers. The mother was on long-term thromboprophylactic warfarin 5 mg/day due to her prosthetic mechanical heart valve following childhood rheumatic fever. Once pregnancy was diagnosed, at 4+0 weeks’ gestation, warfarin was discontinued and low-molecular-weight heparin was started. Warfarin was recommenced at 12+1 weeks’ gestation after a small maternal stroke. Neonatal dysmorphic facial features were noted, most obviously nasal hypoplasia (figure 1). The hypoplastic upper airw...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 19, 2023 Category: Perinatology & Neonatology Authors: Birbal, R., Olaniyi, O., Clarke, P. Tags: Images in neonatal medicine Source Type: research
Women's reproductive traits and cerebral small-vessel disease: A two-sample Mendelian randomization study
CONCLUSION: Our findings do not convincingly support a causal effect of women's reproductive factors on CSVD. Future studies are warranted to investigate specific estrogen-related physiological changes in women, which may inform current researchers on the causal mechanisms involved in cerebral small-vessel disease progression.PMID:37064189 | PMC:PMC10098092 | DOI:10.3389/fneur.2023.1064081
Source: Cancer Control - April 17, 2023 Category: Cancer & Oncology Authors: Zhenqian Wang Jiawen Lu Weipin Weng Jie Zhang Source Type: research
Prevalence and diagnostic value of non-criteria antiphospholipid antibodies for antiphospholipid syndrome in Chinese patients
ConclusionAdditional detection of non-criteria aPLs including aPC IgG/M, aPE IgG/M/A, aPI IgG/M, aSM IgG/M, and aPA IgG/M could assist in APS diagnosis. The positivity of certain aPLs was statistically associated with both criteria and extra-criteria APS clinical manifestations.
Source: Frontiers in Immunology - April 12, 2023 Category: Allergy & Immunology Source Type: research
Letter to the Editor Regarding ‘A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?’
We read with interest the article by Ozdil et al. about a three day-old female neonate who was diagnosed with venous sinus thrombosis (VST) which was complicated by a subacute, partial ischemic stroke in the territory of the right middle cerebral artery.1 The age of the stroke was estimated at 14-28 days before birth.1 Because the mother suffered a mild coronvirus disease-19 (COVID-19) infection during the initial weeks of the third trimester (gestational weeks 27-30), VST in the fetus was causally related to the severe, acute respiratory syndrome-coronavirus type-2 (SARS-CoV-2) infection of the mother.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research
Age of onset of cerebral venous thrombosis: the BEAST study
CONCLUSIONS: Women suffer CVT 9 years earlier in comparison to men. Female patients with multiple (⩾1) risk factors suffer CVT ~12 years earlier compared to those with no identifiable risk factors.PMID:37021156 | PMC:PMC10069208 | DOI:10.1177/23969873221148267
Source: Atherosclerosis - April 6, 2023 Category: Cardiology Authors: Redoy Ranjan Gie Ken-Dror Ida Martinelli Elvira Grandone Sini Hiltunen Erik Lindgren Maurizio Margaglione Veronique Le Cam Duchez Aude Bagan Triquenot Marialuisa Zedde Michelangelo Mancuso Ynte M Ruigrok Brad Worrall Jennifer J Majersik Jukka Putaala Elen Source Type: research
Preventing Adverse Cardiovascular Outcomes in Pregnancy Complicated by Obesity
AbstractPurpose of ReviewObesity is a chronic disease that is becoming increasingly prevalent, and more individuals of reproductive age have obesity prior to becoming pregnant. Obesity in pregnancy is associated with short- and long-term adverse consequences for both the birthing person and their offspring which have been associated with increased long-term cardiovascular morbidity and mortality. The goal of this review is to discuss what is currently understood about the relationship between maternal obesity and adverse pregnancy outcomes (APOs), the association between APOs and future cardiovascular disease (CVD) risk, a...
Source: Current Obstetrics and Gynecology Reports - April 6, 2023 Category: OBGYN Source Type: research
ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Stroke-related risk factors during pregnancy in women who underwent metabolic and bariatric surgery compared with women who have not undergone metabolic and bariatric surgery
Stroke during pregnancy is rare, occurring in 30 of 100,000 pregnancies and accounting for 7% of maternal deaths in the United States from 2016 to 2018. Metabolic and bariatric surgery (MBS) has been shown to reduce symptoms of chronic conditions that are risk factors for stroke, including hypertension, hypercholesterolemia, and diabetes in women. However, little is known about the impact of MBS on stroke risk during pregnancy.
Source: Surgery for Obesity and Related Diseases - March 31, 2023 Category: Surgery Authors: Kara M. Christopher, Xiaoyi Gao, Ahmed Abdelsalam, Brian Miremadi, Jordan Scott, Chike Ilorah, Pamela Xaverius, Guillermo Linares Tags: Original article Source Type: research
Stroke-related risk factors during pregnancy in women who had metabolic and bariatric surgery compared to women without metabolic and bariatric surgery.
Stroke during pregnancy is rare, occurring in 30 of 100,000 pregnancies, and accounting for 7% of maternal deaths in the United States from 2016 to 2018. Metabolic and bariatric surgery (MBS) have been shown to reduce symptoms of chronic conditions that are risk factors for stroke, including hypertension, hypercholesterolemia, and diabetes in women. However, little is known about the impact of MBS on stroke risk during pregnancy.
Source: Surgery for Obesity and Related Diseases - March 31, 2023 Category: Surgery Authors: Kara Christopher, Xiaoyi Gao, Ahmed Abdelsalam, Brian Miremadi, Jordan Scott, Chike Ilorah, Pamela Xaverius, Guillermo Linares Tags: Original articles Source Type: research
Preeclampsia history and postpartum risk of cerebrovascular disease and cognitive impairment: Potential mechanisms
Hypertensive disorders of pregnancy such as preeclampsia, eclampsia, superimposed preeclampsia, and gestational hypertension are major causes of fetal and maternal morbidity and mortality. Women with a history of hypertensive pregnancy disorders have increased risk of stroke and cognitive impairments later in life. Moreover, women with a history of preeclampsia have increased risk of mortality from diseases including stroke, Alzheimer’s disease, and cardiovascular disease. The underlying pathophysiological mechanisms are currently not fully known. Here, we present clinical, epidemiological, and preclinical studies focuse...
Source: Frontiers in Physiology - March 31, 2023 Category: Physiology Source Type: research
Women's reproductive traits and cerebral small-vessel disease: A two-sample Mendelian randomization study
ConclusionOur findings do not convincingly support a causal effect of women's reproductive factors on CSVD. Future studies are warranted to investigate specific estrogen-related physiological changes in women, which may inform current researchers on the causal mechanisms involved in cerebral small-vessel disease progression.
Source: Frontiers in Neurology - March 30, 2023 Category: Neurology Source Type: research
Hypertensive disorders of pregnancy and long-term risk of maternal stroke —a systematic review and meta-analysis
Hypertensive disorders of pregnancy are associated with a long-term risk for cardiovascular disease among parous patients later in life. However, relatively little is known about whether hypertensive disorders of pregnancy are associated with an increased risk for ischemic stroke or hemorrhagic stroke in later life. This systematic review aimed to synthesize the available literature on the association between hypertensive disorders of pregnancy and the long-term risk for maternal stroke.
Source: American Journal of Obstetrics and Gynecology - March 27, 2023 Category: OBGYN Authors: Matthew P. Brohan, Fionn P. Daly, Louise Kelly, Fergus P. McCarthy, Ali S. Khashan, Karolina Kublickiene, Peter M. Barrett Tags: Systematic Review Source Type: research
Hypertensive disorders of pregnancy and long-term risk of maternal stroke – A systematic review and meta-analysis
Source: American Journal of Obstetrics and Gynecology - March 27, 2023 Category: OBGYN Authors: Matthew P Brohan, Fionn P Daly, Louise Kelly, Fergus P Mccarthy, Ali S Khashan, Karolina Kublickiene, Peter M Barrett Tags: Systematic Review Source Type: research
