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Total 1466 results found since Jan 2013.

Hypertensive Disorders in Pregnancy and Mortality at Delivery Hospitalization - United States, 2017-2019
MMWR Morb Mortal Wkly Rep. 2022 Apr 29;71(17):585-591. doi: 10.15585/mmwr.mm7117a1.ABSTRACTHypertensive disorders in pregnancy (HDPs), defined as prepregnancy (chronic) or pregnancy-associated hypertension, are common pregnancy complications in the United States.* HDPs are strongly associated with severe maternal complications, such as heart attack and stroke (1), and are a leading cause of pregnancy-related death in the United States.† CDC analyzed nationally representative data from the National Inpatient Sample to calculate the annual prevalence of HDP among delivery hospitalizations and by maternal characteristics, a...
Source: MMWR Morb Mortal Wkl... - April 28, 2022 Category: Epidemiology Authors: Nicole D Ford Shanna Cox Jean Y Ko Lijing Ouyang Lisa Romero Tiffany Colarusso Cynthia D Ferre Charlan D Kroelinger Donald K Hayes Wanda D Barfield Source Type: research

Pregnancy and stroke risk in women
Neurobiol Dis. 2022 Apr 24:105735. doi: 10.1016/j.nbd.2022.105735. Online ahead of print.ABSTRACTStroke associated with pregnancy and post-partum occurs in about 30 per 100,000 deliveries, and includes subtypes of ischemic and hemorrhagic stroke as well as cerebral venous sinus thrombosis (CVST). There are a wide variety of underlying causes and risk factors, some that are common to both pregnant and non-pregnant women, and others that are unique to pregnancy. Although some of the strokes that occur may be a direct result of the pregnancy itself, such as hypertensive disorders of pregnancy, others could be anticipated or p...
Source: Neurobiology of Disease - April 27, 2022 Category: Neurology Authors: Constance Katsafanas Cheryl Bushnell Source Type: research

Reproductive complications after stroke: long-lasting impairment of GnRH neuronal network?
Biol Reprod. 2022 Apr 26:ioac080. doi: 10.1093/biolre/ioac080. Online ahead of print.ABSTRACTSome studies have demonstrated that stroke may increase the risk of pregnancy complications and early menopause. In addition, preclinical investigations revealed the middle cerebral artery occlusion could affect hypothalamus. Since hypothalamus is the core of central circuits regulating reproductive processes, impairment of hypothalamic GnRH neuronal network following stroke might be manifested in long-lasting reproductive disorders.PMID:35470856 | DOI:10.1093/biolre/ioac080
Source: Biology of Reproduction - April 26, 2022 Category: Reproduction Medicine Authors: Mohammad Saied Salehi Sareh Pandamooz Amin Tamadon Mohammad Reza Jafarzadeh Shirazi Afshin Borhani-Haghighi Source Type: research

Preconception leisure-time physical activity and family history of stroke and myocardial infarction associate with preterm delivery: findings from a Norwegian cohort
Preterm birth poses short and long-term health consequences for mothers and offspring including cardiovascular disease sequelae. However, studies evaluating preexisting family history of cardiovascular disease...
Source: BMC Pregnancy and Childbirth - April 20, 2022 Category: OBGYN Authors: Tone Engen, Katrine Mari Owe, Julie Horn, Gerhard Sulo, Øyvind Erik Næss, Petur Benedikt Juliusson, Nils-Halvdan Morken and Grace Margrethe Egeland Tags: Research Source Type: research

Trends in the Incidence and Risk Factors of Pregnancy-Associated Stroke
The objective of this review is to summarize studies on time trends of PAS in relation to trends in the prevalence of stroke risk factors in pregnant women. Seven retrospective national healthcare register-based cohort studies from the US, Canada, UK, Sweden, and Finland were identified. Five studies from the US, Canada, and Finland reported an increasing trend of PAS. Potential biases include more sensitive diagnostics and improved stroke awareness among pregnant women and professionals toward the end of the study period. However, the concurrent increase in the prevalence of several stroke risk factors among pregnant wome...
Source: Frontiers in Neurology - April 11, 2022 Category: Neurology Source Type: research

Experiences and actions related to living with type 1 diabetes during the COVID-19 pandemic in Norway: a qualitative study conducted during July to December 2020
CONCLUSIONS: Patients experienced an increased psychosocial burden of T1DM and difficulties from a disrupted daily life affecting T1DM self-management routines. Uncertainty-reducing behaviours and actions to adapt to the situation provided a general sense of coping despite these difficulties. Tailored information and follow-up by telephone or video call was emphasised to reduce uncertainly distress and support adequate diabetes T1DM self-management.PMID:35393314 | DOI:10.1136/bmjopen-2021-056027
Source: Cancer Control - April 8, 2022 Category: Cancer & Oncology Authors: Karin Pleym Marjolein Memelink Iversen Anders Brostr öm Source Type: research

Data from New VOYAGER PAD Analyses at ACC.22 Reinforce Benefit of XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Peripheral Artery Disease (PAD) and Various Co-Morbid Conditions
RARITAN, N.J., April 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from new analyses from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefit of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) in reducing severe vascular events in patients with PAD after lower-extremity revascularization (LER), a procedure that restores blood flow to the legs. Data from the two analyses demonstrate the role that the XARELTO® vascular dose plays in PAD patients with and without chronic kidney disease (CKD) and in PAD patients with and ...
Source: Johnson and Johnson - April 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Understanding maternal postnatal blood pressure changes following hypertensive disorders in pregnancy: protocol for a prospective cohort study
Introduction Hypertensive disorders occur in approximately 10% of women during pregnancy. There is robust population-based data to show that women who have hypertension in pregnancy are much more likely to develop cardiovascular disease (CVD) in the postpartum period. Women with a hypertensive disorder of pregnancy (HDP) are twice more at risk of heart disease and stroke, and four times more likely to develop hypertension after birth. Two out of three women who had HDP will die from CVD. Recent evidence suggests that young women with HDP develop signs of CVD in the immediate postpartum period, rather than several decades l...
Source: BMJ Open - April 1, 2022 Category: General Medicine Authors: Sheehan, E., Wang, C., Cauldwell, M., Bick, D., Thilaganathan, B. Tags: Open access Obstetrics and gynaecology Source Type: research

Epidemiology of cerebral venous sinus thrombosis and cerebral venous sinus thrombosis with thrombocytopenia in the United States, 2018 and 2019
CONCLUSIONS: Our findings provide recent and comprehensive data on the epidemiology of CVST and CVST with thrombocytopenia.PMID:35284775 | PMC:PMC8901465 | DOI:10.1002/rth2.12682
Source: Thrombosis and Haemostasis - March 14, 2022 Category: Hematology Authors: Amanda B Payne Alys Adamski Karon Abe Nimia L Reyes Lisa C Richardson William Craig Hooper Laura A Schieve Source Type: research

Polyuria, Polydipsia and Possible Diabetes Insipidus?
Discussion The body is smart. It has mechanisms for maintaining balances within the body in a closely controlled manner but allows for a variety of states. This is very true for fluid balance in the body which is highly controlled between almost all of the major body organ systems. When fluid is low, the sensor sends signals for us to drink, and conserves fluid until we can. When the fluid is high, the kidneys excrete the excess and sends signals not to drink. Usually it works very well. While there are many pathological states that can cause polyuria and/or polydipsia, the most common reason is excessive fluid intake beca...
Source: PediatricEducation.org - March 7, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

The venous system during pregnancy. Part 1: physiologic considerations on the venous system
The confluence of anatomic and physiologic gestational changes, pre-existing and pregnancy-related comorbidities, surgery and anesthesia has significant implications for maternal hemodynamics. Genetic and hemodynamic factors alter endothelial migration and branching during embryogenesis to create separate venous and arterial systems, 1 which subsequently possess distinct responses to disease processes (e.g. venous insufficiency, thromboembolism, stroke). 2
Source: International Journal of Obstetric Anesthesia - February 24, 2022 Category: Anesthesiology Authors: L.C. Tsen, S. Gelman Tags: Review Article Source Type: research