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Condition: Pregnancy

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Total 1466 results found since Jan 2013.

Maternal echocardiographic changes in twin pregnancies with and without pre-eclampsia
CONCLUSIONS: The maternal cardiovascular system is severely altered by a twin pregnancy with and without HPD. Despite a low total vascular resistance, cardiac changes in normotensive twins are comparable with those seen in singletons complicated by HDP reflecting the high cardiovascular demand imposed by a twin pregnancy. This article is protected by copyright. All rights reserved.PMID:35000243 | DOI:10.1002/uog.24852
Source: The Ultrasound Review of Obstetrics and Gynecology - January 9, 2022 Category: Radiology Authors: V Giorgione K Melchiorre J O'Driscoll A Khalil R Sharma B Thilaganathan Source Type: research

Long-term association of pregnancy and maternal brain structure: the Rotterdam Study
AbstractThe peripartum period is the highest risk interval for the onset or exacerbation of psychiatric illness in women ’s lives. Notably, pregnancy and childbirth have been associated with short-term structural and functional changes in the maternal human brain. Yet the long-term effects of pregnancy on maternal brain structure remain unknown. We investigated a large population-based cohort to examine the asso ciation between parity and brain structure. In total, 2,835 women (mean age 65.2 years; all free from dementia, stroke, and cortical brain infarcts) from the Rotterdam Study underwent magnetic resonance i...
Source: European Journal of Epidemiology - January 6, 2022 Category: Epidemiology Source Type: research

The Diabetes-Cardiovascular Connection in Women: Understanding the Known Risks, Outcomes, and Implications for Care
AbstractPurpose of ReviewCardiovascular disease (CVD) complications constitute about 50 –70% of mortality in people with diabetes. However, there remains a persistently greater relative increase in CVD morbidity and mortality in women with diabetes than in their male counterparts. This review presents recent evidence for the risks, outcomes, and management implications for women with diabetes.Recent FindingsCompared to men, women have higher BMI and more adverse cardiovascular risk profile at time of diabetes diagnosis with greater risk for coronary heart disease, stroke, vascular dementia, and heart failure. Pregnancy-s...
Source: Current Diabetes Reports - January 1, 2022 Category: Endocrinology Source Type: research

Migraine and Medical Ramifications: A Comprehensive Overview Based on Observational Study Meta-Analyses
Conclusion: The results showed that migraine increased the risk of 29 health outcomes, though lowered the risk of breast cancer. However, evidence quality was graded as high only for angina. The evidence quality of ischaemic stroke, stroke, MACCE, WMAs, and asthma was graded as moderate. All remaining 24 outcomes had an evidence grade of “weak.”
Source: Frontiers in Neurology - December 24, 2021 Category: Neurology Source Type: research

FDA Approves Two New Indications for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, Dec. 20, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved two pediatric indications for XARELTO® (rivaroxaban): the treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients from birth to less than 18 years after at least five days of initial parenteral (injected or intravenous) anticoagulant treatment; and thromboprophylaxis (prevention of blood clots and blood-clot related events) in children aged two years and older with congenital heart disease who have...
Source: Johnson and Johnson - December 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Synthesizing Core Outcome Sets for outcomes research in cohort studies: a systematic review
CONCLUSION: This COS synthesis generated outcome constructs that are of high value to stakeholders (participants, health providers, services), relevant to life course research, and could position cohorts for trial capabilities.IMPACT: We synthesized existing Core Outcome Sets as a transparent methodology that could prioritize outcomes for lifecourse cohorts with an interventional focus. "Quality of life", "adverse events", "medication use", "hospitalization", and "mortality" are important outcomes across pregnancy, newborns, childhood, and early-to-mid-adulthood (the age range relevant to parents). Other common outcomes (s...
Source: Pediatric Research - December 18, 2021 Category: Pediatrics Authors: Erica Musgrove Loretta Gasparini Katie McBain Susan A Clifford Simon A Carter Helena Teede Melissa Wake Source Type: research

Cervical Artery Dissection in Young Women: Risk of Recurrence During Subsequent Pregnancies
Conclusion In this study, there were no CAD recurrences during subsequent pregnancies or postpartum, irrespective of the type of delivery. Thus, pregnancy after a history of CAD appears to be safe.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Assif, M., Lamy, C., De Gaalon, S., Caroit, Y., Bourcier, R., Preterre, C., Guillon, B. Tags: Stroke in young adults, Carotid artery dissection Research Source Type: research

Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke
ConclusionsIn patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost. This retrospective study was underpowered, which may limit these implications. Further prospective studies are warranted to confirm these results.
Source: Neurocritical Care - December 13, 2021 Category: Neurology Source Type: research

Indications for transfusion in the management of sickle cell disease
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):696-703. doi: 10.1182/hematology.2021000307.ABSTRACTThe transfusion of red blood cells (RBCs) is a crucial treatment for sickle cell disease (SCD). While often beneficial, the frequent use of transfusions is associated with numerous complications. Transfusions should be offered with specific guidelines in mind. Here we present updates to the indications for transfusion of RBCs in SCD. We review recent publications and include expert perspectives from hematology and transfusion medicine. For some clinical indications, such as ischemic stroke, the role of transfusio...
Source: Hematology ASH Education Program - December 10, 2021 Category: Hematology Authors: Hyojeong Han Lisa Hensch Ven ée N Tubman Source Type: research