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IJERPH, Vol. 19, Pages 16741: 1000 Days: The & ldquo;WeCare Generation & rdquo; Program & mdash;The Ultimate Model for Improving Human Mental Health and Economics: The Study Protocol
Discussion: An overall rate of return on investment (ROI) statistically significant 13.0% per annum with an associated benefit/cost ratio (BCR) of 6.3 is expected as the primary outcome of the “WeCare Generation” program. Our proposed model predicts a new medical paradigm aiming to empower new generations, with a strong return on economy and health.
Source: International Journal of Environmental Research and Public Health - December 13, 2022 Category: Environmental Health Authors: Orlando Uccellini Andrea Benlodi Emanuele Caroppo Loredana Cena Gianluca Esposito Isabel Fernandez Maria Ghazanfar Antonio Imbasciati Francesco Longo Marianna Mazza Giuseppe Marano Renata Nacinovich Antonio Pignatto Arthur Rolnick Marco Trivelli Elena Spa Tags: Article Source Type: research

Real-World Study Confirms Benefit of XARELTO ® (rivaroxaban) for Secondary Prevention of Venous Thromboembolism in Cancer Patients
TITUSVILLE, NJ, December 9, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced observational data from eight years of clinical practice showing that the oral Factor Xa inhibitor XARELTO® (rivaroxaban) is associated with comparable effectiveness and safety to the Factor Xa inhibitor apixaban for the treatment of cancer-associated thromboembolism (CAT) in a broad cohort of patients with various cancer types. Patients with CAT are at a higher risk of venous thromboembolism (VTE), which is the second-leading cause of death in people with cancer.1Data from the Observational Study in Cancer-A...
Source: Johnson and Johnson - December 9, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

A neonatal case of cerebral venous thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, İpek Dokurel Cetin Tags: Case Report Source Type: research

A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, Ipek Dokurel Cetin Tags: Case Report Source Type: research

A comparison of the effect of Swedish massage with and without chamomile oil on labor outcomes and maternal satisfaction of the childbirth process: a randomized controlled trial
ConclusionThe results of the study showed that using Swedish massage techniques with or without chamomile oil can improve labor outcomes. Swedish massage using chamomile oil was associated with better results compared to the same massage without using chamomile oil.Clinical trial code IRCT20200513047430N1.
Source: European Journal of Medical Research - November 25, 2022 Category: Research Source Type: research

Clinical Features and Risk Factors of Mortality in Patients with Posterior Reversible Encephalopathy Syndrome
CONCLUSIONS: Our results indicate that PRES could be considered as a sign of a very high-risk patient. We also demonstrated that heart failure and stroke were independent risk factors for death in patients with PRES; moreover, pregnancy was a protective factor.PMID:36419591 | PMC:PMC9678458 | DOI:10.1155/2022/9401661
Source: Behavioural Neurology - November 24, 2022 Category: Neurology Authors: Hong-Wei Cui Ru-Yi Lei Bo-Ai Zhang Source Type: research

Preventive Approaches in Women's Neurology: Prepartum, Pregnancy, and Postpartum
Semin Neurol DOI: 10.1055/a-1958-0633Women's neurology is the subspecialty within neurology concerned with the distinct healthcare needs of women. In this article, we review current literature and expert management strategies regarding disease-specific neurologic concerns of women, with an emphasis on issues related to contraception, pregnancy, and lactation. Health conditions that we discuss in this article include epilepsy, headache, stroke, multiple sclerosis, and Chiari I malformation. Current findings on neurologic disease in women suggest that many women with neurologic disease can safely manage their disease during ...
Source: Seminars in Neurology - November 17, 2022 Category: Neurology Authors: Kirkpatrick, Laura Waters, Janet O'Neal, Mary Angela Tags: Review Article Source Type: research

Pregnancy and cardio-embolic stroke: To recanalize or not ?
Ayush Agarwal, Priyanka Sehrawat, Venugopalan Y Vishnu, Ajay Garg, Mamta B Singh, Vinay Goyal, MV Padma SrivastavaAnnals of Indian Academy of Neurology 2022 25(5):985-988
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ayush Agarwal Priyanka Sehrawat Venugopalan Y Vishnu Ajay Garg Mamta B Singh Vinay Goyal MV Padma Srivastava Source Type: research

Hereditary thrombotic thrombocytopenic purpura and COVID-19: Impacts of vaccination and infection in this rare disease
DISCUSSION: The risk of an acute episode triggered by COVID-19 seems higher than following vaccination in hTTP patients, who can be safely vaccinated against SARS-CoV-2.PMID:36284639 | PMC:PMC9585384 | DOI:10.1002/rth2.12814
Source: Thrombosis and Haemostasis - October 26, 2022 Category: Hematology Authors: Erika Tarasco Anne Sophie von Krogh Radomira Hrdlickova Thomas R Braschler Teresa Iwaniec Paul N Kn öbl Eriko Hamada Oleg Pikovsky Stefan Farese Odit Gutwein Petr Kessler Nina H Schultz Charis von Auer Jerzy Windyga Kenneth Friedman Ingrid Hrachovinova J Source Type: research

U.S. FDA Approves TECVAYLI ™ (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., October 25, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) approved TECVAYLI™ (teclistamab-cqyv) for the treatment of adult patients with relapsed or refractory multiple myeloma, who previously received four or more prior lines of therapy, including a proteasome inhibitor, immunomodulatory drug and anti-CD38 monoclonal antibody.1 TECVAYLI™ is a first-in-class, bispecific T-cell engager antibody that is administered as a subcutaneous treatment.1 This off-the-shelf (or ready to use) therapy uses innovative science to ac...
Source: Johnson and Johnson - October 25, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Pregnancy-related stroke through a neuropsychology lens
Conclusions: Pregnancy-related stroke can be associated with marked functional disability and decreased quality of life, and it is notable that prevalence rates are increasing. Presenting at a time when people are experiencing adjustment to a new phase of life, and most commonly affecting women of color and other vulnerable populations, pregnancy-related stroke is a unique condition warranting special attention within the broader stroke discourse. This review aims to serve as a starting point for neuropsychologists to better understand the unique attributes of pregnancy-related stroke through a neuropsychology lens. Beyond...
Source: The Clinical Neuropsychologist - October 10, 2022 Category: Psychiatry & Psychology Authors: Erin Sullivan-Baca Yosefa A Modiano Kathryn M McKenney Anne R Carlew Source Type: research