Atypical EEG Responses to Nonverbal Emotionally Charged Stimuli in Children with ASD.
This study focused on auditory emotional perception in children with low-functioning autism and investigated the children's response to emotionally charged nonverbal sounds which regularly induced emotional response in typically developing (TD) peers. An EEG was conducted, and emotional reactions were assessed using analog scales and images of presented sounds with additional images during the presentation of emotional stimuli. The results showed that EEG and emotional responses to the fearful sounds were similar in TD children and children with autism spectrum disorders (ASD). Both groups of children showed an increase in...
Source: Behavioural Neurology - October 23, 2020 Category: Neurology Authors: Portnova GV, Maslennikova AV Tags: Behav Neurol Source Type: research

Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury.
Conclusion: To the best of our knowledge, this is the first study to report that CISD2 is an upstream modulator of the PPAR-β/NF-κB proinflammatory signaling pathway in neural cells, and that WBM can mitigate the injury-induced downregulation of CISD2 in SCI mice and LPS-stimulated ALT astrocytes. PMID: 33062068 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 20, 2020 Category: Neurology Authors: Kung WM, Lin CC, Kuo CY, Juin YC, Wu PC, Lin MS Tags: Behav Neurol Source Type: research

Corrigendum to "A Longitudinal Examination of the Hopelessness Theory of Depression in People Who Have Multiple Sclerosis".
Corrigendum to "A Longitudinal Examination of the Hopelessness Theory of Depression in People Who Have Multiple Sclerosis". Behav Neurol. 2020;2020:1805958 Authors: Kneebone II, Guerrier S, Dunmore E, Jones E, Fife-Schaw C Abstract [This corrects the article DOI: 10.1155/2015/190405.]. PMID: 33062069 [PubMed] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 20, 2020 Category: Neurology Authors: Kneebone II, Guerrier S, Dunmore E, Jones E, Fife-Schaw C Tags: Behav Neurol Source Type: research

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease.
Abstract Objectives: Retina abnormalities are related to cognitive disorders in patients with Alzheimer's disease (AD). Retinal amyloid beta (Aβ) can be labeled by curcumin. We measured Aβ content in the cerebrum and retina of APPswe/PS1dE9 (APP) transgenic mice with early age to investigate the correlation between cerebrum and retina. Methods: APP mice and age-matched wild-type mice were investigated every month from age 2 months to 6 months to assess changes in Aβ content in the retina and cerebrum. At the beginning of each month, mice were fed a curcumin diet (50 mg/kg/day) for 7 cons...
Source: Behavioural Neurology - October 10, 2020 Category: Neurology Authors: Mei X, Yang M, Zhu L, Zhou Q, Li X, Chen Z, Zou C Tags: Behav Neurol Source Type: research

Comparison of Performance on the Clock Drawing Test Using Three Different Scales in Dialysis Patients.
Abstract Background: The clock drawing test (CDT) is frequently used to detect changes in cognition. Multiple scales of varying length have been published to assess performance. The aim of this study is to compare the CDT performance measured by three scales among a sample of nondemented patients on renal dialysis and identify the variables that affect performance. Methodology. This is a cross-sectional study performed at the dialysis unit at King Saud University Medical City. Eighty-nine dialysis patients performed the CDT. The CDT was scored by the methods of Rouleau et al. (RCS 10-point), Babins et al. (BCS 18-...
Source: Behavioural Neurology - October 10, 2020 Category: Neurology Authors: Muayqil TA, Tarakji AR, Khattab AM, Balbaid NT, Al-Dawalibi AM, Alqarni SA, Hazazi RA, Alanazy MH Tags: Behav Neurol Source Type: research

Abnormal Homocysteine Metabolism: An Insight of Alzheimer's Disease from DNA Methylation.
Abstract Alzheimer's disease (AD) is a chronic neurodegenerative disease in the central nervous system that has complex pathogenesis in the elderly. The current review focuses on the epigenetic mechanisms of AD, according to the latest findings. One of the best-characterized chromatin modifications in epigenetic mechanisms is DNA methylation. Highly replicable data shows that AD occurrence is often accompanied by methylation level changes of the AD-related gene. Homocysteine (Hcy) is not only an intermediate product of one-carbon metabolism but also an important independent risk factor of AD; it can affect the cog...
Source: Behavioural Neurology - September 25, 2020 Category: Neurology Authors: Pi T, Liu B, Shi J Tags: Behav Neurol Source Type: research

Evaluating Executive Functions in Patients with Juvenile Myoclonic Epilepsy Using Frontal Assessment Battery.
Conclusions: In summary, JME patients had deficits in different aspects of executive functions. FAB is a useful clinical tool for evaluation of executive functions in JME patients. PMID: 32963634 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 25, 2020 Category: Neurology Authors: Sanjari Moghaddam H, Doost Hoseini M, Khaleghi MR, Tafakhori A, Dolatshahi M, Pourmirbabaei S, Agah E, Meshkat S, Aghamollaii V Tags: Behav Neurol Source Type: research

A Novel Metabolic Connectome Method to Predict Progression to Mild Cognitive Impairment.
Conclusion: Overall, the results suggest that our proposed individual metabolic connectome method has great potential to predict whether MCI patients will progress to AD. The metabolic connectome may help to identify brain metabolic dysfunction and build a clinically applicable biomarker to predict the MCI progression. PMID: 32908613 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 12, 2020 Category: Neurology Authors: Wang M, Yan Z, Xiao SY, Zuo C, Jiang J Tags: Behav Neurol Source Type: research

Conversational Therapy through Semi-Immersive Virtual Reality Environments for Language Recovery and Psychological Well-Being in Post Stroke Aphasia.
Abstract Aphasia is a highly disabling acquired language disorder generally caused by a left-lateralized brain damage. Even if traditional therapies have been shown to induce an adequate clinical improvement, a large percentage of patients are left with some degree of language impairments. Therefore, new approaches to common speech therapies are urgently needed in order to maximize the recovery from aphasia. The recent application of virtual reality (VR) to aphasia rehabilitation has already evidenced its usefulness in promoting a more pragmatically oriented treatment than conventional therapies (CT). In the prese...
Source: Behavioural Neurology - August 26, 2020 Category: Neurology Authors: Giachero A, Calati M, Pia L, La Vista L, Molo M, Rugiero C, Fornaro C, Marangolo P Tags: Behav Neurol Source Type: research

Neuropsychological and Emotional Functioning in Patients with Cushing's Syndrome.
Abstract Patients with Cushing's syndrome (CS) frequently report impairments in cognitive and emotional functioning. Given neuroimaging research that implicates alterations in structure and function in the brain in this population, goals of this study were to investigate neuropsychological and emotional functioning, with particular emphasis on complex attention and memory. In a clinical sample of 18 adults with CS referred for neuropsychological evaluation (age 41.6 ± 10.6, 72% Caucasian), patients' most common subjective complaints were in attention and increased irritability. On objective testing, patient...
Source: Behavioural Neurology - August 26, 2020 Category: Neurology Authors: Na S, Fernandes MA, Ioachimescu AG, Penna S Tags: Behav Neurol Source Type: research

Effects of Subthalamic Nucleus Deep Brain Stimulation on Facial Emotion Recognition in Parkinson's Disease: A Critical Literature Review.
Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for Parkinson's disease (PD). Nevertheless, DBS has been associated with certain nonmotor, neuropsychiatric effects such as worsening of emotion recognition from facial expressions. In order to investigate facial emotion recognition (FER) after STN DBS, we conducted a literature search of the electronic databases MEDLINE and Web of science. In this review, we analyze studies assessing FER after STN DBS in PD patients and summarize the current knowledge of the effects of STN DBS on FER. The majority of studies, which had ...
Source: Behavioural Neurology - July 30, 2020 Category: Neurology Authors: Kalampokini S, Lyros E, Lochner P, Fassbender K, Unger MM Tags: Behav Neurol Source Type: research

Identifying the Symptom Severity in Obsessive-Compulsive Disorder for Classification and Prediction: An Artificial Neural Network Approach.
Abstract The present study is aimed at identifying the most prominent determinants of OCD along with their strength to classify the OCD patients from healthy controls. The data for this cross-sectional study were collected from 200 diagnosed OCD patients and 400 healthy controls. The respondents were selected through purposive sampling and interviewed by using the Y-BOCS scale with the addition of a factor, worth of an individual in his family. The validity and reliability of data were assessed through Cronbach's alpha and confirmatory factor analysis. Artificial Neural Network (ANN) modeling was adopted to determ...
Source: Behavioural Neurology - July 19, 2020 Category: Neurology Authors: Shahzad MN, Suleman M, Ahmed MA, Riaz A, Fatima K Tags: Behav Neurol Source Type: research

Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors.
Conclusion: Rutin, partially, through a neuroprotective effect on the hippocampus exerted antidepressant-like effect. We concluded that NMDA receptors, at least in part, mediated the beneficial effect of rutin. PMID: 32587637 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - June 27, 2020 Category: Neurology Authors: Anjomshoa M, Boroujeni SN, Ghasemi S, Lorigooini Z, Amiri A, Balali-Dehkordi S, Amini-Khoei H Tags: Behav Neurol Source Type: research

A Novel PRRT2 Variant in Chinese Patients Suffering from Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsion.
Abstract PRRT2 mutations are the major causative agent of paroxysmal kinesigenic dyskinesia with infantile convulsion (PKD/IC). The study is aimed at screening PRRT2 gene mutations in patients who suffered from PKD/IC in Chinese population. Thirteen Chinese patients with PKD/IC were screened randomly for coding exons of the PRRT2 gene mutation along with 50 ethnically coordinated control people. Nine (2 unaffected) and 4 of the patients showed familial PKD/IC and apparently sporadic cases, respectively. We identified 5 different PRRT2 mutations in 10 individuals, including 8 familial and 2 apparently sporadic case...
Source: Behavioural Neurology - June 10, 2020 Category: Neurology Authors: Baldi S, Zhu JL, Hu QY, Wang JL, Zhang JB, Zhang SH Tags: Behav Neurol Source Type: research

Factors Associated with Anxiety and Depression among Diabetes, Hypertension, and Heart Failure Patients at Dessie Referral Hospital, Northeast Ethiopia.
This study is aimed at assessing factors associated with anxiety and depression among diabetes, hypertension, and heart failure patients at Dessie Referral Hospital, Northeast Ethiopia. Methods: An institutional-based cross-sectional study was conducted in Dessie Referral Hospital from February 22, 2019 to April 6, 2019. A total of 404 diabetic, hypertension, and heart failure patients were included through systematic sampling technique. The data were collected by face-to-face interview. After data collection, the data were cleaned and presented with text, graphs, and tables. Multivariable binary logistic regression w...
Source: Behavioural Neurology - June 10, 2020 Category: Neurology Authors: Edmealem A, Olis CS Tags: Behav Neurol Source Type: research

The Main Determinants for Suicidal Ideation in a Romanian Cohort of Multiple Sclerosis Patients.
Conclusions: The prevalence of SC is higher in patients with MS compared to the general population. Their occurrence is mostly influenced by the disease itself (duration, relapses, acquired disability) and also by depression and lack of education. PMID: 32399081 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Romaniuc A, Bălaşa R, Ştirbu N, Maier S, Andone S, Bajko Z, Bărcuţean L, Voidăzan S, Moţăţăianu A Tags: Behav Neurol Source Type: research

Neuropsychological Changes in Complex Regional Pain Syndrome (CRPS).
de JH Abstract Complex Regional Pain Syndrome (CRPS) is a poorly understood chronic pain condition of multifactorial origin. CRPS involves sensory, motor, and autonomic symptoms primarily affecting one extremity. Patients can also present with neuropsychological changes such as reduced attention to the CRPS-affected extremity, reminiscent of hemispatial neglect, yet in the absence of any brain lesions. However, this "neglect-like" framework is not sufficient to characterise the range of higher cognitive functions that can be altered in CRPS. This comprehensive literature review synthesises evidence of ne...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Halicka M, Vittersø AD, Proulx MJ, Bultitude JH Tags: Behav Neurol Source Type: research

Social Cognition in Rehabilitation Context: Different Evolution of Affective and Cognitive Theory of Mind in Mild Cognitive Impairment.
Abstract Maintaining social skills such as Theory of Mind (ToM) competences is important to counteract the conversion into dementia in Mild Cognitive Impairment (MCI). Multidimensional nonpharmacological interventions demonstrated their potential in improving cognitive and behavioral abilities; however, little is known about the long-term effect of such interventions on social skills in people with MCI. The aim of this longitudinal study was to monitor ToM competences considering both cognitive and affective domains in an amnestic MCI (aMCI) sample involved in a home-based multistimulation treatment (MST@H). 30 aM...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Rossetto F, Baglio F, Massaro D, Alberoni M, Nemni R, Marchetti A, Castelli I Tags: Behav Neurol Source Type: research

Small Fiber Neuropathy: Clinicopathological Correlations.
Janszky J, Komoly S Abstract Small fiber neuropathy develops due to the selective damage of the thin fibers of peripheral nerves. Many common diseases can cause this condition, including diabetes, infections, autoimmune and endocrine disorders, but it can occur due to genetic alterations, as well. Eighty-five skin biopsy-proven small-fiber neuropathy cases were analyzed. Forty-one (48%) cases were idiopathic; among secondary types, hypothyreosis (9.4%), diabetes mellitus (7%), cryoglobulinemia (7%), monoclonal gammopathy with unproved significance (4.7%), Sjögren's disease (3%), and paraneoplastic neuropathy ...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Pál E, Fülöp K, Tóth P, Deli G, Pfund Z, Janszky J, Komoly S Tags: Behav Neurol Source Type: research

Word Processing Is Faster than Picture Processing in Alzheimer's Disease.
Conclusions: Our results suggested that the processing speed in AD patients may have reduced, even if the semantic memory were preserved. These data indicated that the difference in the processing speeds by the type of stimuli (pictures, words, and nonsense syllables) may be a character of AD patients. PMID: 32399085 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Meguro K, Takahashi Y, Nakatsuka M, Oonuma J, Kumai K, Kasai M, Yamaguchi S Tags: Behav Neurol Source Type: research

"Olfactory Three-Needle" Enhances Spatial Learning and Memory Ability in SAMP8 Mice.
"Olfactory Three-Needle" Enhances Spatial Learning and Memory Ability in SAMP8 Mice. Behav Neurol. 2020;2020:2893289 Authors: Wang Y, Wang Q, Ren B, Guo T, Qiang J, Cao H, Gao Y, Liu Z, Gao X, Zhu B Abstract As one of the most important therapies in complementary and alternative medicine, acupuncture has been used in the treatment of Alzheimer's disease (AD). Acupuncture of "olfactory three-needle" manipulation can improve the cognitive ability of AD patients. However, the mechanism of "olfactory three-needle" in AD remains largely unknown. Here, we identified that the &q...
Source: Behavioural Neurology - May 8, 2020 Category: Neurology Authors: Wang Y, Wang Q, Ren B, Guo T, Qiang J, Cao H, Gao Y, Liu Z, Gao X, Zhu B Tags: Behav Neurol Source Type: research

Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study.
Conclusion: The preliminary results found that the patients in the action observation therapy and active control intervention groups had comparable benefits, suggesting that the 2 treatments might be used as an alternative to each other. A further large-scale study with at least 20 patients in each group to validate the study findings is needed. This trial is registered with NCT02871700. PMID: 32377266 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 8, 2020 Category: Neurology Authors: Hsieh YW, Lin YH, Zhu JD, Wu CY, Lin YP, Chen CC Tags: Behav Neurol Source Type: research

Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia.
This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer's disease are also present during the disorder's preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating b...
Source: Behavioural Neurology - May 1, 2020 Category: Neurology Authors: Meilán JJG, Martínez-Sánchez F, Martínez-Nicolás I, Llorente TE, Carro J Tags: Behav Neurol Source Type: research

Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review.
Abstract In recent years, neuroendoscopic treatment of hydrocephalus and various ventricular pathologies has become increasingly popular. It is considered by many as the first-choice treatment for the majority of these cases. However, neurocognitive complications following ventricular neuroendoscopic procedures may occur leading mostly to amnesia, which might have a grave effect on the patient's quality of life. Studies assessing neurocognitive complications after ventricular neuroendoscopic procedures are sparse. Therefore, we conducted a systematic review assessing the available literature of neurocognitive comp...
Source: Behavioural Neurology - April 18, 2020 Category: Neurology Authors: Soleman J, Guzman R Tags: Behav Neurol Source Type: research

Primary Cognitive Factors Impaired after Glioma Surgery and Associated Brain Regions.
The objective of this study was to investigate primary cognitive factors affecting not only simple cognitive tasks but also several other cognitive tasks and associated brain regions. Patients with glioma in the left (n = 33) and the right (n = 21) hemisphere participated in the study. Seven neuropsychological tasks from five cognitive domains were conducted pre- and 6 months postoperation. Factor analyses were conducted to identify "primary" common cognitive functions affecting the task performance in left and right glioma groups. Next, lesion analyses were performed using voxel-based lesion-symptom mapping (VLS...
Source: Behavioural Neurology - April 18, 2020 Category: Neurology Authors: Niki C, Kumada T, Maruyama T, Tamura M, Kawamata T, Muragaki Y Tags: Behav Neurol Source Type: research

Chronic Pain Hurts the Brain: The Pain Physician's Perspective.
a J, Nagy F PMID: 32273914 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - April 11, 2020 Category: Neurology Authors: Feher G, Szok D, Rodríguez-Saldaña J, Nagy F Tags: Behav Neurol Source Type: research

Too Real to Be Virtual: Autonomic and EEG Responses to Extreme Stress Scenarios in Virtual Reality.
In this study, 3 female participants were experiencing VR scenarios with stressful content and their activity of the autonomic nervous system and EEG were recorded. It has been discovered that virtual reality can evoke acute stress reactions accompanied by activation of the sympathetic nervous system and a decrease in the activity of the parasympathetic nervous system. The high-stress response is accompanied by a decrease in the power of the EEG, and, on the contrary, the activation of the avoidance reaction is accompanied by an increase in the power of the EEG alpha waves. Therefore, the use of stressful VR content can ca...
Source: Behavioural Neurology - April 8, 2020 Category: Neurology Authors: Fadeev KA, Smirnov AS, Zhigalova OP, Bazhina PS, Tumialis AV, Golokhvast KS Tags: Behav Neurol Source Type: research

Changes in Physiological and Pathological Behaviours Produced by Deep Microelectrode Implantation Surgery in Rats: A Temporal Analysis.
In conclusion, microelectrode implantation surgeries modified some physiological and pathological behaviours; therefore, it is important to consider this fact when it is working with animal models. PMID: 32211080 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - March 28, 2020 Category: Neurology Authors: Chiprés-Tinajero GA, Núñez-Ochoa MA, Medina-Ceja L Tags: Behav Neurol Source Type: research

Maternal Separation Early in Life Alters the Expression of Genes Npas4 and Nr1d1 in Adult Female Mice: Correlation with Social Behavior.
Abstract Early-life stress affects neuronal plasticity of the brain regions participating in the implementation of social behavior. Our previous studies have shown that brief and prolonged separation of pups from their mothers leads to enhanced social behavior in adult female mice. The goal of the present study was to characterize the expression of genes (which are engaged in synaptic plasticity) Egr1, Npas4, Arc, and Homer1 in the prefrontal cortex and dorsal hippocampus of adult female mice with a history of early-life stress. In addition, we evaluated the expression of stress-related genes: glucocorticoid and m...
Source: Behavioural Neurology - March 21, 2020 Category: Neurology Authors: Ryabushkina YA, Reshetnikov VV, Bondar NP Tags: Behav Neurol Source Type: research

Personality Factors and Subjective Cognitive Decline: The FACEHBI Cohort.
L, Boada M, Alegret M, On Behalf Of The Facehbi Study Abstract Individuals with subjective cognitive decline (SCD) have the perception of memory problems without showing impairment on standardized cognitive tests. SCD has been associated with an increased risk of developing Alzheimer's disease (AD). Neuroticism and openness personality dimensions have also been associated with SCD and AD. From the aforementioned, we aimed to ascertain whether the dimensions and traits defined by the Zuckerman-Kuhlman Personality Questionnaire (ZKPQ) differentiate between individuals with SCD and the general population (GP). A tota...
Source: Behavioural Neurology - March 11, 2020 Category: Neurology Authors: Muñoz N, Gomà-I-Freixanet M, Valero S, Rodríguez-Gómez O, Sanabria A, Pérez-Cordón A, Hernández I, Marquié M, Mir I, Martín E, Benaque A, Ruiz A, Tarraga L, Boada M, Alegret M, On Behalf Of The Facehbi Study Tags: Behav Neurol Source Type: research

False Memory in Alzheimer's Disease.
Abstract Patients with Alzheimer's Disease (AD) not only are suffering from amnesia but also are prone to memory distortions, such as experiencing detailed and vivid recollections of episodic events that have never been encountered (i.e., false memories). To describe and explain these distortions, we offer a review to synthesize current knowledge on false memory in AD into a framework allowing for better understanding of the taxonomy and phenomenology of false memories and of the cognitive mechanisms that may underlie false memory formation in AD. According to this review, certain phenomenological characteristics ...
Source: Behavioural Neurology - March 11, 2020 Category: Neurology Authors: El Haj M, Colombel F, Kapogiannis D, Gallouj K Tags: Behav Neurol Source Type: research

Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats.
Abstract Objective: Propofol is a classical anesthetic and induces consciousness loss, and gamma-aminobutyric-acid-type-A (GABA-A) receptor is its target. Righting reflex is associated with conscious response. The nucleus basalis (NB) acts as a major relay between the reticular activating system and the frontal cortex (FC). Propofol may mediate righting reflex by affecting GABA-A receptor in NB. Methods: Fifty male SD rats (250-350 g) were divided into parts I and II. In part I, 20 male SD rats were randomly divided into control group (CG) and NB-lesion group (NG, ibotenic acid-induced NB lesion). In p...
Source: Behavioural Neurology - March 11, 2020 Category: Neurology Authors: Xing Y, Li K, Jiao Y, Li Z Tags: Behav Neurol Source Type: research

Associations between Age-Related Changes in the Core Vestibular Projection Pathway and Balance Ability: A Diffusion Tensor Imaging Study.
Conclusion: The results suggested that there was a relationship between DTI parameters in the vestibular neural pathway and balance according to aging. PMID: 32104515 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - February 29, 2020 Category: Neurology Authors: Yeo SS, Kwon JW, Cho IH Tags: Behav Neurol Source Type: research

Potential Benefits of Physical Activity in MCI and Dementia.
Abstract Physical activity improves overall health and reduces the risk of many negative health outcomes and may be effective in improving cognition, independent functioning, and psychological health in older adults. Given the evidence linking physical activity with improvements in various aspects of health and functioning, interventions exploring pathways for decreasing risk of dementia in those with mild cognitive impairment (MCI) and improving outcomes for those with dementia are of critical importance. The present review highlights the work examining physical activity interventions in order to achieve a compre...
Source: Behavioural Neurology - February 29, 2020 Category: Neurology Authors: Nuzum H, Stickel A, Corona M, Zeller M, Melrose RJ, Wilkins SS Tags: Behav Neurol Source Type: research

MST4 Kinase Inhibitor Hesperadin Attenuates Autophagy and Behavioral Disorder via the MST4/AKT Pathway in Intracerebral Hemorrhage Mice.
Abstract Background: The aim of this study was to explore the role of hesperadin in intracerebral hemorrhage (ICH) mice, with the involvement of the mammalian ste20-like kinase 4 (MST4)/AKT signaling pathway. Methods: All mice were divided into four groups: sham group, sham+hesperidin group, ICH group, and ICH+hesperadin group. The effects of hesperadin were assessed on the basis of brain edema and neurobehavioral function. Furthermore, we observed MST4, AKT, phosphorylation of AKT (pAKT), and microtubule-associated protein light chain 3 (LC3) by western blotting. Protein localization of MST4 and LC3 was dete...
Source: Behavioural Neurology - February 26, 2020 Category: Neurology Authors: Wu X, Wu J, Hu W, Wang Q, Liu H, Chu Z, Lv K, Xu Y Tags: Behav Neurol Source Type: research

Behavioural Changes in Mice after Getting Accustomed to the Mirror.
We examined whether mice preferred mirrors, whether plastic tapes on their heads increased their interest, and whether mice accustomed to mirrors learnt its physical phenomenon. Mice were significantly more interested in live stranger mice than mirrors. Mice with tape on their heads spent more time before mirrors. Becoming accustomed to mirrors did not change their behaviour. Mice accustomed to mirrors had significantly increased interest in photos of themselves over those of strangers and cage-mates. These results indicated that mice visually recognized plastic tape adherent to reflected individuals. Mice accustomed to mi...
Source: Behavioural Neurology - February 26, 2020 Category: Neurology Authors: Ueno H, Suemitsu S, Murakami S, Kitamura N, Wani K, Takahashi Y, Matsumoto Y, Okamoto M, Ishihara T Tags: Behav Neurol Source Type: research

Associations of Alpha and Beta Interhemispheric EEG Coherences with Indices of Attentional Control and Academic Performance.
Conclusions: Lower TBR, an indicator of attentional control, was associated with higher alpha and beta interhemispheric coherences measured with eyes open at sites overlying the frontal, temporal, and occipital cortices. Changes in EEG coherences and TBRs might be useful as neurophysiological measures of neuroplasticity and the efficacy of strategies for preventing academic underachievement and treatments for improving academic performance. PMID: 32089751 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - February 26, 2020 Category: Neurology Authors: Gorantla VR, Tedesco S, Chandanathil M, Maity S, Bond V, Lewis C, Millis RM Tags: Behav Neurol Source Type: research

Framingham Risk Stratification of Middle-Aged Migraineurs.
Conclusion: Our article draws attention to the higher cardiovascular risk profile of middle-aged migraineurs and highlights the deficiency of primary prevention. Pain physicians must be aware of the cardiovascular aspects of migraine and holistic approach is required instead of focusing only on pain and pain relief. PMID: 32089752 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - February 26, 2020 Category: Neurology Authors: Bank G, Kapus K, Meszaros J, Mak K, Pohl M, Pusch G, Fejes E, Tibold A, Feher G Tags: Behav Neurol Source Type: research

Parkinson's Symptoms and Caregiver Burden and Mental Health: A Cross-Cultural Mediational Model.
;or T Abstract Informal caregivers are critical in the care of individuals with Parkinson's disease (PD) and spend substantial time providing care, which may be associated with negative caregiver outcomes such as burden and mental health issues. Although research in the United States and Europe has generally supported these relations, there is very limited research on PD caregiving in Latin America. The current study examined the following connections in a sample of PD caregivers from the United States (N = 105) and Mexico (N = 148): (a) PD-related impairments (motor and nonmotor symptoms) and caregiver burden, (b...
Source: Behavioural Neurology - December 26, 2019 Category: Neurology Authors: Smith ER, Perrin PB, Tyler CM, Lageman SK, Villaseñor T Tags: Behav Neurol Source Type: research

Feeding Behavior of Mice under Different Food Allocation Regimens.
Abstract Social interaction, a basic survival strategy for many animal species, helps maintain a social environment that has limited conflict. Social dominance has a dramatic effect on motivation. Recent evidence suggests that some primate and nonprimate species display aversive behavior toward food allocation regimens that differ from their peers. Thus, we examined the behaviors displayed by mice under different food allocation regimens. We analyzed changes in food intake using several parameters. In the same food condition, the mice received the same food; in the quality different condition, the mice received di...
Source: Behavioural Neurology - December 26, 2019 Category: Neurology Authors: Ueno H, Suemitsu S, Murakami S, Kitamura N, Wani K, Takahashi Y, Matsumoto Y, Okamoto M, Ishihara T Tags: Behav Neurol Source Type: research

Diverse Linguistic Development in Prelingually Deaf Children with Cochlear Implants.
We report 4 prelingually deaf children (mean age = 10.5; SD = 1.08), affected by a genetically determined bilateral deafness, due to GJB2 gene mutation Cx26. Each implanted child underwent a systematic assessment of speech perception and production, as well as of lexical, morphologic, and syntactic skills in both comprehension and production. Notwithstanding similar clinical histories and similarly good postimplant pure-tone audiometry, two of the four children fared very poorly in speech audiometry, whereas the other two children gained very good results. We suggest that the language impairment detected in (some) i...
Source: Behavioural Neurology - December 26, 2019 Category: Neurology Authors: De Stefano P, Pisani F, Cossu G Tags: Behav Neurol Source Type: research

Therapeutic Approaches for Peripheral and Central Neuropathic Pain.
cute;csei L Abstract Neuropathic pain is a chronic secondary pain condition, which is a consequence of peripheral or central nervous (somatosensory) system lesions or diseases. It is a devastating condition, which affects around 7% of the general population. Numerous etiological factors contribute to the development of chronic neuropathic pain. It can originate from the peripheral part of the nervous system such as in the case of trigeminal or postherpetic neuralgia, peripheral nerve injury, painful polyneuropathies, or radiculopathies. Central chronic neuropathic pain can develop as a result of spinal cord or bra...
Source: Behavioural Neurology - December 26, 2019 Category: Neurology Authors: Szok D, Tajti J, Nyári A, Vécsei L Tags: Behav Neurol Source Type: research

Community's Perception and Attitude towards People with Epilepsy in Ethiopia.
Conclusions: The knowledge about the cause, possible susceptibility, better treatment options, and attitude of the participants were similar to other low-income settings. The negative attitude was high and multidimensional. All stakeholders must work to increase awareness about the cause, symptoms, and treatment options for epilepsy and to decrease the negative attitude of the community. PMID: 31814856 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 11, 2019 Category: Neurology Authors: Fekadu W, Mekonen T, Bitew S, Mekonnen TC, Menberu M, Shewangizaw S Tags: Behav Neurol Source Type: research

Validation of a New Cognitive Screening Method for Stroke Patients.
Conclusions: This study shows promising results for this new cognitive screening tool's ability to identify poststroke cognitive decline and patients' need for further detailed neuropsychological examination. PMID: 31781293 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 1, 2019 Category: Neurology Authors: Saar K, Nyrkkö H, Tolvanen A, Kuikka P, Poutiainen E, Aro T Tags: Behav Neurol Source Type: research

Cognitive Neurorehabilitation in Acquired Neurological Brain Injury.
PMID: 31781294 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 1, 2019 Category: Neurology Authors: Messinis L, Kosmidis MH, Nasios G, Dardiotis E, Tsaousides T Tags: Behav Neurol Source Type: research

CZYH Alleviates β-Amyloid-Induced Cognitive Impairment and Inflammation Response via Modulation of JNK and NF-κB Pathway in Rats.
In conclusion, the present study suggests that CZYH could improve learning and memory abilities and relieve neuron loss in Aβ 25-35-induced rats, at least partly through inhibition of the neuroinflammatory response via inhibiting the JNK-dependent NF-κB activation, indicating that CZYH might be a promising formula for the treatment of AD. PMID: 31781295 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 1, 2019 Category: Neurology Authors: Deng Y, Ye L, Yu C, Yin C, Shi J, Gong Q Tags: Behav Neurol Source Type: research

Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model.
Abstract Objective: To explore the effects of sevoflurane on the latency and error times of the passive avoidance and levels of PSD-95 and AMPA receptors in the hippocampus. We evaluated the effects of sevoflurane on short-term memory in adult mice and explored the possible mechanism. Methods: 144 Kunming mice (2-3 months, 30-35 g) were randomly divided into two groups A (n = 64) and B (n = 80) and received the dark-avoidance (DA) and step-down avoidance (SA) tests, respectively. The groups DA and SA were further divided into control (inhaled 40% O2 2 h) and sevoflurane (3.3% sevoflurane and 40%...
Source: Behavioural Neurology - November 29, 2019 Category: Neurology Authors: Jiao Y, Fan H, Wang K, Lu S Tags: Behav Neurol Source Type: research

Epidemiology of Alzheimer's Disease and Dementia in Arab Countries: A Systematic Review.
Conclusion: This systematic review highlights the need for population-based studies to provide necessary information for developing preventive and curative strategies specific to the Arab region. PMID: 31772681 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - November 29, 2019 Category: Neurology Authors: El-Metwally A, Toivola P, Al-Rashidi M, Nooruddin S, Jawed M, AlKanhal R, Razzak HA, Albawardi N Tags: Behav Neurol Source Type: research

A Neuropsychological Rehabilitation Program for Cognitive Impairment in Psychiatric and Neurological Conditions: A Review That Supports Its Efficacy.
aurre-Elorza L, Ojeda N Abstract Neuropsychological rehabilitation has been the focus of much scientific research over the past decades due to its efficacy in different pathologies. Advances in the neuropsychology field have led to improvements and changes in neuropsychological interventions, which in turn have given rise to different approaches and rehabilitation programs. REHACOP is an integrative neuropsychological rehabilitation program designed by specialist neuropsychologists. With an integrated bottom-up and top-down approach, REHACOP includes neurocognition, social cognition, and daily living tasks hierarc...
Source: Behavioural Neurology - November 29, 2019 Category: Neurology Authors: Gómez-Gastiasoro A, Peña J, Ibarretxe-Bilbao N, Lucas-Jiménez O, Díez-Cirarda M, Rilo O, Montoya-Murillo G, Zubiaurre-Elorza L, Ojeda N Tags: Behav Neurol Source Type: research

Behavioral and Neural Changes Induced by a Blended Essential Oil on Human Selective Attention.
Abstract Selective attention refers to the selecting and preferential processing of specific information while simultaneously suppressing irrelevant distractors, activities linked to various cognitive skills and academic achievements. The influence of essential oils on the cognition of humans has been extensively explored. However, the effects of essential oils on human selective attention and the underlying neural mechanisms remain unclear. In the present study, participants were divided into a "blended essential oil" group and a "no essential oil" group and enrolled on a negative priming task...
Source: Behavioural Neurology - November 19, 2019 Category: Neurology Authors: Liu J, Cai S, Chen D, Wu K, Liu Y, Zhang R, Chen M, Li X Tags: Behav Neurol Source Type: research