Behavioral Assessment of Unilateral Spatial Neglect with the Catherine Bergego Scale (CBS) Using the Kessler Foundation Neglect Assessment Process (KF-NAP) in Patients with Subacute Stroke during Rehabilitation in Japan
This study is aimed at determining the reliability and validity of the Japanese version of the KF-NAP (KF-NAP-J), evaluating the improvement of neglect assessment with KF-NAP-J, and comparing it with the original CBS for subacute stroke patients. We assessed subacute stroke patients admitted to our intensive rehabilitation hospital. Two KF-NAP-trained occupational therapists (OTs) assessed 22 patients. Before implementing the KF-NAP at the hospital, two other OTs assessed the other 23 patients using the CBS. We evaluated the interrater reliability of the KF-NAP and CBS using intraclass correlation coefficients (ICC) for th...
Source: Behavioural Neurology - February 25, 2021 Category: Neurology Authors: Daisuke Nishida Katsuhiro Mizuno Masatoshi Tahara Shiori Shindo Yuki Watanabe Hiroki Ebata Tetsuya Tsuji Source Type: research

Does the Personality of Patients with Parkinson's Disease Affect the Decision to Perform Deep Brain Stimulation Surgery? A Cross-Sectional Study in a Chinese Cohort.
Abstract We investigated whether the personality of patients with Parkinson's disease (PD) before subthalamic brain stimulation differed from patients receiving drug treatments and whether the personality of patients affected surgical decisions. We recruited 38 patients with advanced PD scheduled for deep brain stimulation (DBS), 40 patients with PD receiving the very best medical treatment, and 51 healthy control subjects. All participants were evaluated by the Minnesota multiphasic personality inventory-1 (MMPI-1). PD patients who were candidates for DBS did not exhibit any significant differences in personality...
Source: Behavioural Neurology - February 14, 2021 Category: Neurology Authors: Lin W, Wang D, Yang L, Zhu J, Ge J, Zuo C, Wang Y Tags: Behav Neurol Source Type: research

Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress.
Conclusion: We concluded that the antidepressant-like effects of limonene are probably mediated through inhibition of neuroinflammation and attenuation of nitrite levels in the hippocampus. PMID: 33564342 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - February 12, 2021 Category: Neurology Authors: Lorigooini Z, Boroujeni SN, Sayyadi-Shahraki M, Rahimi-Madiseh M, Bijad E, Amini-Khoei H Tags: Behav Neurol Source Type: research

Ultrarapid Endoscopic-Aided Hematoma Evacuation in Patients with Thalamic Hemorrhage.
In this study, we present our experience in the treatment of patients with thalamic hemorrhage by ultrarapid MIS evacuation. This retrospective analysis enrolled seven patients treated with ultrarapid MIS evacuation of thalamic hemorrhage. Seven patients treated with EVD with similar ICH score were included as match control. Primary endpoints included rebleeding, morbidity, and mortality. Hematoma evacuation rate was evaluated by comparing the pre- and postoperative computed tomography (CT) scans. Glasgow Outcome Scale Extended (GOSE) and modified Rankin Score (mRS) were noted at the 6-month and 1-year postoperative follow...
Source: Behavioural Neurology - February 7, 2021 Category: Neurology Authors: Chen KY, Kung WM, Kuo LT, Huang AP Tags: Behav Neurol Source Type: research

Efficacy of a Smart Antisnore Pillow in Patients with Obstructive Sleep Apnea Syndrome.
Conclusions: We concluded that the SAP is an effective positional therapy device for patients with OSAS of mild-to-moderate severity. PMID: 33510821 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - January 31, 2021 Category: Neurology Authors: Chung TT, Lee MT, Ku MC, Yang KC, Wei CY Tags: Behav Neurol Source Type: research

Normative and Equated Data of the Original and Basic Versions of the Montreal Cognitive Assessment among Community Dwelling Saudi Arabians.
Abstract Introduction: Currently, there are standard and basic versions of the MoCA, the latter designed for those with lower educational achievements. Community-based normative data on these versions of the MoCA from Arabic populations are deficient, and there is little data demonstrating how both scales perform in comparison. We aim to obtain normative performances from both versions and equate the measures of both scales. Methods: Community-based recruitment of healthy volunteers ≥ 18 years of age. Participants underwent testing with both versions. Demographic data was collected with regard to ag...
Source: Behavioural Neurology - January 29, 2021 Category: Neurology Authors: Muayqil TA, Alamri NK, Alqahtani AM, Julaidan SS, Alsuhaibani R, Nafisah I, Alkeridy WA, Aljafen BN, Alanazy MH Tags: Behav Neurol Source Type: research

Prevalence and Associated Factors of Visual Hallucinations in Patients with Vascular Cognitive Impairment.
Abstract Visual hallucinations (VHs) are striking features for dementia, especially dementia with Lewy bodies (DLB). We aimed to study the frequency and associated factors of VH in vascular cognitive impairment (VCI) and investigate the feasibility of clinically diagnosing the mixed pathology of VCI with DLB. This is a multicentre registration study. A consecutive series of VCI patients with and without dementia were enrolled. Frequency of VH and associated factors, including age, gender, education, disease severity, DLB clinical features, vascular risk factors, cognitive function, and neuropsychiatric symptoms, w...
Source: Behavioural Neurology - January 29, 2021 Category: Neurology Authors: Chen CL, Hsu MH, Hung CH, Chiu PY, Liu CH Tags: Behav Neurol Source Type: research

Basolateral Amygdala but Not Medial Prefrontal Cortex Contributes to Chronic Fluoxetine Treatments for PTSD Symptoms in Mice.
Abstract Do chronic fluoxetine treatments reduced footshock-induced posttraumatic stress disorder (PTSD) symptoms, including fear and comorbid depression, in the situational reminder phase? Moreover, are the subareas of the medial prefrontal cortex (mPFC), including the cingulate cortex 1 (Cg1), prelimbic cortex (PrL), infralimbic cortex (IL), and basolateral amygdala (BLA), involved in the fluoxetine amelioration of PTSD symptoms? These two crucial issues were addressed in the present study. All mice were injected with chronic fluoxetine or normal saline treatments for the adaptation (14 days), footshock fear con...
Source: Behavioural Neurology - December 12, 2020 Category: Neurology Authors: Yu YH, Ou CY, Shyu BC, Huang ACW Tags: Behav Neurol Source Type: research

Relationship between Depression Symptoms and Different Types of Measures of Obesity (BMI, SAD) in US Women.
Conclusions: SAD had a better correlation with clinical depression symptoms than BMI, especially regarding severe depression symptoms. PMID: 33299495 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 12, 2020 Category: Neurology Authors: Zhou Y, Yang G, Peng W, Zhang H, Peng Z, Ding N, Guo T, Cai Y, Deng Q, Chai X Tags: Behav Neurol Source Type: research

The Effect of Differential Attentional Focus Strategies on the Performance of Military Elite Shooters.
Conclusion: The results of the study support the hypothesis that external-relevant attentional focus produced better scores, better accumulation, more stability at the target center, and less average fluctuation. Therefore, this attentional focus strategy improves performance precision of military elite shooters. PMID: 33294054 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 10, 2020 Category: Neurology Authors: Amini A, Vaezmousavi M Tags: Behav Neurol Source Type: research

Hypomania, Depression, Euthymia: New Evidence in Parkinson's Disease.
Abstract The field related to mood disorders in Parkinson's disease (PD) is fragmented. The aim of this cohort observational study was to evaluate whether the episodes of mood alteration could appear in different disease stages and to verify how nonmotor symptoms were led off into different stages. We enrolled 93 PD outpatients (three groups: drug naive-DN; not exhibiting motor fluctuations-n-MF; and exhibiting motor fluctuations-MF) and 50 healthy controls. Mood state was assessed through the Internal State Scale (ISS) while depressive symptoms were evaluated through the Beck Depression Inventory-II (BDI-II), non...
Source: Behavioural Neurology - December 10, 2020 Category: Neurology Authors: Canesi M, Lavolpe S, Cereda V, Ranghetti A, Maestri R, Pezzoli G, Rusconi ML Tags: Behav Neurol Source Type: research

Milestones and Timescale of Poststroke Recovery: A Cohort Study.
Conclusion: Systematic recording of the timescale of poststroke recovery showed that motor milestone reacquisition happens, on average and when attainable, in less than 30 days in our sample of patients. The present study underscores the importance of the Fugl-Meyer score as a possible predictor for better improvement in reacquisition times of milestone functional recovery. PMID: 33282006 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 9, 2020 Category: Neurology Authors: Loi M, Zaliani A, Abbamonte M, Ferrari EP, Maestri R, Trojano L, Balbi P Tags: Behav Neurol Source Type: research

Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior.
Conclusions: Thus, combined housing of immature mice of different age groups affects mouse behavior after maturation. Appropriate prematuration housing conditions are crucial to eliminate the uncontrollable bias caused by age-related social stratification. PMID: 33273986 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - December 6, 2020 Category: Neurology Authors: Ueno H, Suemitsu S, Murakami S, Kitamura N, Wani K, Takahashi Y, Matsumoto Y, Okamoto M, Ishihara T Tags: Behav Neurol Source Type: research

AEBP1 Promotes Glioblastoma Progression and Activates the Classical NF- κB Pathway.
Conclusion: Upregulated AEBP1 in GBM promotes GBM cell proliferation, migration, and invasion and facilitates tumor growth in vivo by activating the classical NF-κB pathway. PMID: 33224311 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - November 24, 2020 Category: Neurology Authors: Guo K, Song L, Chang J, Cao P, Liu Q Tags: Behav Neurol Source Type: research

Facial Emotion Recognition and Polymorphisms of Dopaminergic Pathway Genes in Children with ASD.
Conclusions: Children with ASD experience a deficit in facial emotion recognition. Certain SNPs in the dopaminergic pathway genes are associated with accuracy in recognizing selective facial emotions in children with ASD. PMID: 33204361 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - November 20, 2020 Category: Neurology Authors: Liu Z, Liu J, Zhang Z, Yu H, Hu F Tags: Behav Neurol Source Type: research

Protective Factors Modulate the Risk of Beta Amyloid in Alzheimer's Disease.
Conclusion: Higher average CGM based on FDG modified the progression to AD, indicating a protective function. The results suggest that the inclusion of this CGM measured by FDG would enrich clinical trial design and that increasing CGM along with the use of anti-Abeta agents might be a potential prevention strategy for AD. PMID: 33178360 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - November 13, 2020 Category: Neurology Authors: Zhou B, Tanabe K, Kojima S, Teramukai S, Fukushima M, Neuroimaging Initiative TAD Tags: Behav Neurol Source Type: research

Machine Learning Based on a Multiparametric and Multiregional Radiomics Signature Predicts Radiotherapeutic Response in Patients with Glioblastoma.
Abstract Methods: The MRI images, genetic data, and clinical data of 152 patients with GBM were analyzed. 122 patients from the TCIA dataset (training set: n = 82; validation set: n = 40) and 30 patients from local hospitals were used as an independent test dataset. Radiomics features were extracted from multiple regions of multiparameter MRI. Kaplan-Meier survival analysis was used to verify the ability of the imaging signature to predict the response of GBM patients to radiotherapy before an operation. Multivariate Cox regression including radiomics signature and preoperative clinical risk factors was used to fu...
Source: Behavioural Neurology - November 12, 2020 Category: Neurology Authors: Pan ZQ, Zhang SJ, Wang XL, Jiao YX, Qiu JJ Tags: Behav Neurol Source Type: research

Burnout among Nurses Working in Ethiopia.
Conclusions: Burnout affects two out of five nurses in Ethiopia. Therefore, effective interventions and strategies are required to reduce burnout among nurses. PMID: 33123299 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 31, 2020 Category: Neurology Authors: Hailay A, Aberhe W, Mebrahtom G, Zereabruk K, Gebreayezgi G, Haile T Tags: Behav Neurol Source Type: research

Association between Neuron-Specific Enolase Gene Polymorphism and Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
Conclusions: The results show that rs2071419 and rs3213434 are susceptible sites of DEACMP. The NSE C allele of rs2071419 and T allele of rs3213434 and the haplotypes GGTTTC and CCTTTC may be risk factors for DEACMP. PMID: 33123300 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 31, 2020 Category: Neurology Authors: Xu L, Liu X, Zhao J, Zeng J, Gu J, Zhang X, Zhang F, Han Y, Li W, Zhang P, Gu R Tags: Behav Neurol Source Type: research

Sexual Satisfaction in Fully Ambulatory People with Multiple Sclerosis: Does Disability Matter?
Abstract Primary sexual dysfunctions (SD) are a direct result of neurological changes that affect the sexual response. Secondary SD result from the symptoms that do not directly involve nervous pathways to the genital system, such as bladder and bowel problems, fatigue, spasticity, or muscle weakness. Tertiary SD are the result of disability-related psychosocial and cultural issues that can interfere with sexual feelings and experiences. The aim of this study was to assess the sexual satisfaction (SS) in people with multiple sclerosis (PwMS) without significant mobility impairment and to estimate the influence of ...
Source: Behavioural Neurology - October 28, 2020 Category: Neurology Authors: Dobrakowski P, Machowska-Majchrzak A, Labuz-Roszak B, Niewiadomska E, Pierzchala K Tags: Behav Neurol Source Type: research

Atypical EEG Responses to Nonverbal Emotionally Charged Stimuli in Children with ASD.
This study focused on auditory emotional perception in children with low-functioning autism and investigated the children's response to emotionally charged nonverbal sounds which regularly induced emotional response in typically developing (TD) peers. An EEG was conducted, and emotional reactions were assessed using analog scales and images of presented sounds with additional images during the presentation of emotional stimuli. The results showed that EEG and emotional responses to the fearful sounds were similar in TD children and children with autism spectrum disorders (ASD). Both groups of children showed an increase in...
Source: Behavioural Neurology - October 23, 2020 Category: Neurology Authors: Portnova GV, Maslennikova AV Tags: Behav Neurol Source Type: research

Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury.
Conclusion: To the best of our knowledge, this is the first study to report that CISD2 is an upstream modulator of the PPAR-β/NF-κB proinflammatory signaling pathway in neural cells, and that WBM can mitigate the injury-induced downregulation of CISD2 in SCI mice and LPS-stimulated ALT astrocytes. PMID: 33062068 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 20, 2020 Category: Neurology Authors: Kung WM, Lin CC, Kuo CY, Juin YC, Wu PC, Lin MS Tags: Behav Neurol Source Type: research

Corrigendum to "A Longitudinal Examination of the Hopelessness Theory of Depression in People Who Have Multiple Sclerosis".
Corrigendum to "A Longitudinal Examination of the Hopelessness Theory of Depression in People Who Have Multiple Sclerosis". Behav Neurol. 2020;2020:1805958 Authors: Kneebone II, Guerrier S, Dunmore E, Jones E, Fife-Schaw C Abstract [This corrects the article DOI: 10.1155/2015/190405.]. PMID: 33062069 [PubMed] (Source: Behavioural Neurology)
Source: Behavioural Neurology - October 20, 2020 Category: Neurology Authors: Kneebone II, Guerrier S, Dunmore E, Jones E, Fife-Schaw C Tags: Behav Neurol Source Type: research

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease.
Abstract Objectives: Retina abnormalities are related to cognitive disorders in patients with Alzheimer's disease (AD). Retinal amyloid beta (Aβ) can be labeled by curcumin. We measured Aβ content in the cerebrum and retina of APPswe/PS1dE9 (APP) transgenic mice with early age to investigate the correlation between cerebrum and retina. Methods: APP mice and age-matched wild-type mice were investigated every month from age 2 months to 6 months to assess changes in Aβ content in the retina and cerebrum. At the beginning of each month, mice were fed a curcumin diet (50 mg/kg/day) for 7 cons...
Source: Behavioural Neurology - October 10, 2020 Category: Neurology Authors: Mei X, Yang M, Zhu L, Zhou Q, Li X, Chen Z, Zou C Tags: Behav Neurol Source Type: research

Comparison of Performance on the Clock Drawing Test Using Three Different Scales in Dialysis Patients.
Abstract Background: The clock drawing test (CDT) is frequently used to detect changes in cognition. Multiple scales of varying length have been published to assess performance. The aim of this study is to compare the CDT performance measured by three scales among a sample of nondemented patients on renal dialysis and identify the variables that affect performance. Methodology. This is a cross-sectional study performed at the dialysis unit at King Saud University Medical City. Eighty-nine dialysis patients performed the CDT. The CDT was scored by the methods of Rouleau et al. (RCS 10-point), Babins et al. (BCS 18-...
Source: Behavioural Neurology - October 10, 2020 Category: Neurology Authors: Muayqil TA, Tarakji AR, Khattab AM, Balbaid NT, Al-Dawalibi AM, Alqarni SA, Hazazi RA, Alanazy MH Tags: Behav Neurol Source Type: research

Abnormal Homocysteine Metabolism: An Insight of Alzheimer's Disease from DNA Methylation.
Abstract Alzheimer's disease (AD) is a chronic neurodegenerative disease in the central nervous system that has complex pathogenesis in the elderly. The current review focuses on the epigenetic mechanisms of AD, according to the latest findings. One of the best-characterized chromatin modifications in epigenetic mechanisms is DNA methylation. Highly replicable data shows that AD occurrence is often accompanied by methylation level changes of the AD-related gene. Homocysteine (Hcy) is not only an intermediate product of one-carbon metabolism but also an important independent risk factor of AD; it can affect the cog...
Source: Behavioural Neurology - September 25, 2020 Category: Neurology Authors: Pi T, Liu B, Shi J Tags: Behav Neurol Source Type: research

Evaluating Executive Functions in Patients with Juvenile Myoclonic Epilepsy Using Frontal Assessment Battery.
Conclusions: In summary, JME patients had deficits in different aspects of executive functions. FAB is a useful clinical tool for evaluation of executive functions in JME patients. PMID: 32963634 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 25, 2020 Category: Neurology Authors: Sanjari Moghaddam H, Doost Hoseini M, Khaleghi MR, Tafakhori A, Dolatshahi M, Pourmirbabaei S, Agah E, Meshkat S, Aghamollaii V Tags: Behav Neurol Source Type: research

A Novel Metabolic Connectome Method to Predict Progression to Mild Cognitive Impairment.
Conclusion: Overall, the results suggest that our proposed individual metabolic connectome method has great potential to predict whether MCI patients will progress to AD. The metabolic connectome may help to identify brain metabolic dysfunction and build a clinically applicable biomarker to predict the MCI progression. PMID: 32908613 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 12, 2020 Category: Neurology Authors: Wang M, Yan Z, Xiao SY, Zuo C, Jiang J Tags: Behav Neurol Source Type: research

Conversational Therapy through Semi-Immersive Virtual Reality Environments for Language Recovery and Psychological Well-Being in Post Stroke Aphasia.
Abstract Aphasia is a highly disabling acquired language disorder generally caused by a left-lateralized brain damage. Even if traditional therapies have been shown to induce an adequate clinical improvement, a large percentage of patients are left with some degree of language impairments. Therefore, new approaches to common speech therapies are urgently needed in order to maximize the recovery from aphasia. The recent application of virtual reality (VR) to aphasia rehabilitation has already evidenced its usefulness in promoting a more pragmatically oriented treatment than conventional therapies (CT). In the prese...
Source: Behavioural Neurology - August 26, 2020 Category: Neurology Authors: Giachero A, Calati M, Pia L, La Vista L, Molo M, Rugiero C, Fornaro C, Marangolo P Tags: Behav Neurol Source Type: research

Neuropsychological and Emotional Functioning in Patients with Cushing's Syndrome.
Abstract Patients with Cushing's syndrome (CS) frequently report impairments in cognitive and emotional functioning. Given neuroimaging research that implicates alterations in structure and function in the brain in this population, goals of this study were to investigate neuropsychological and emotional functioning, with particular emphasis on complex attention and memory. In a clinical sample of 18 adults with CS referred for neuropsychological evaluation (age 41.6 ± 10.6, 72% Caucasian), patients' most common subjective complaints were in attention and increased irritability. On objective testing, patient...
Source: Behavioural Neurology - August 26, 2020 Category: Neurology Authors: Na S, Fernandes MA, Ioachimescu AG, Penna S Tags: Behav Neurol Source Type: research

Effects of Subthalamic Nucleus Deep Brain Stimulation on Facial Emotion Recognition in Parkinson's Disease: A Critical Literature Review.
Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for Parkinson's disease (PD). Nevertheless, DBS has been associated with certain nonmotor, neuropsychiatric effects such as worsening of emotion recognition from facial expressions. In order to investigate facial emotion recognition (FER) after STN DBS, we conducted a literature search of the electronic databases MEDLINE and Web of science. In this review, we analyze studies assessing FER after STN DBS in PD patients and summarize the current knowledge of the effects of STN DBS on FER. The majority of studies, which had ...
Source: Behavioural Neurology - July 30, 2020 Category: Neurology Authors: Kalampokini S, Lyros E, Lochner P, Fassbender K, Unger MM Tags: Behav Neurol Source Type: research

Identifying the Symptom Severity in Obsessive-Compulsive Disorder for Classification and Prediction: An Artificial Neural Network Approach.
Abstract The present study is aimed at identifying the most prominent determinants of OCD along with their strength to classify the OCD patients from healthy controls. The data for this cross-sectional study were collected from 200 diagnosed OCD patients and 400 healthy controls. The respondents were selected through purposive sampling and interviewed by using the Y-BOCS scale with the addition of a factor, worth of an individual in his family. The validity and reliability of data were assessed through Cronbach's alpha and confirmatory factor analysis. Artificial Neural Network (ANN) modeling was adopted to determ...
Source: Behavioural Neurology - July 19, 2020 Category: Neurology Authors: Shahzad MN, Suleman M, Ahmed MA, Riaz A, Fatima K Tags: Behav Neurol Source Type: research

Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors.
Conclusion: Rutin, partially, through a neuroprotective effect on the hippocampus exerted antidepressant-like effect. We concluded that NMDA receptors, at least in part, mediated the beneficial effect of rutin. PMID: 32587637 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - June 27, 2020 Category: Neurology Authors: Anjomshoa M, Boroujeni SN, Ghasemi S, Lorigooini Z, Amiri A, Balali-Dehkordi S, Amini-Khoei H Tags: Behav Neurol Source Type: research

A Novel PRRT2 Variant in Chinese Patients Suffering from Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsion.
Abstract PRRT2 mutations are the major causative agent of paroxysmal kinesigenic dyskinesia with infantile convulsion (PKD/IC). The study is aimed at screening PRRT2 gene mutations in patients who suffered from PKD/IC in Chinese population. Thirteen Chinese patients with PKD/IC were screened randomly for coding exons of the PRRT2 gene mutation along with 50 ethnically coordinated control people. Nine (2 unaffected) and 4 of the patients showed familial PKD/IC and apparently sporadic cases, respectively. We identified 5 different PRRT2 mutations in 10 individuals, including 8 familial and 2 apparently sporadic case...
Source: Behavioural Neurology - June 10, 2020 Category: Neurology Authors: Baldi S, Zhu JL, Hu QY, Wang JL, Zhang JB, Zhang SH Tags: Behav Neurol Source Type: research

Factors Associated with Anxiety and Depression among Diabetes, Hypertension, and Heart Failure Patients at Dessie Referral Hospital, Northeast Ethiopia.
This study is aimed at assessing factors associated with anxiety and depression among diabetes, hypertension, and heart failure patients at Dessie Referral Hospital, Northeast Ethiopia. Methods: An institutional-based cross-sectional study was conducted in Dessie Referral Hospital from February 22, 2019 to April 6, 2019. A total of 404 diabetic, hypertension, and heart failure patients were included through systematic sampling technique. The data were collected by face-to-face interview. After data collection, the data were cleaned and presented with text, graphs, and tables. Multivariable binary logistic regression w...
Source: Behavioural Neurology - June 10, 2020 Category: Neurology Authors: Edmealem A, Olis CS Tags: Behav Neurol Source Type: research

The Main Determinants for Suicidal Ideation in a Romanian Cohort of Multiple Sclerosis Patients.
Conclusions: The prevalence of SC is higher in patients with MS compared to the general population. Their occurrence is mostly influenced by the disease itself (duration, relapses, acquired disability) and also by depression and lack of education. PMID: 32399081 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Romaniuc A, Bălaşa R, Ştirbu N, Maier S, Andone S, Bajko Z, Bărcuţean L, Voidăzan S, Moţăţăianu A Tags: Behav Neurol Source Type: research

Neuropsychological Changes in Complex Regional Pain Syndrome (CRPS).
de JH Abstract Complex Regional Pain Syndrome (CRPS) is a poorly understood chronic pain condition of multifactorial origin. CRPS involves sensory, motor, and autonomic symptoms primarily affecting one extremity. Patients can also present with neuropsychological changes such as reduced attention to the CRPS-affected extremity, reminiscent of hemispatial neglect, yet in the absence of any brain lesions. However, this "neglect-like" framework is not sufficient to characterise the range of higher cognitive functions that can be altered in CRPS. This comprehensive literature review synthesises evidence of ne...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Halicka M, Vittersø AD, Proulx MJ, Bultitude JH Tags: Behav Neurol Source Type: research

Social Cognition in Rehabilitation Context: Different Evolution of Affective and Cognitive Theory of Mind in Mild Cognitive Impairment.
Abstract Maintaining social skills such as Theory of Mind (ToM) competences is important to counteract the conversion into dementia in Mild Cognitive Impairment (MCI). Multidimensional nonpharmacological interventions demonstrated their potential in improving cognitive and behavioral abilities; however, little is known about the long-term effect of such interventions on social skills in people with MCI. The aim of this longitudinal study was to monitor ToM competences considering both cognitive and affective domains in an amnestic MCI (aMCI) sample involved in a home-based multistimulation treatment (MST@H). 30 aM...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Rossetto F, Baglio F, Massaro D, Alberoni M, Nemni R, Marchetti A, Castelli I Tags: Behav Neurol Source Type: research

Small Fiber Neuropathy: Clinicopathological Correlations.
Janszky J, Komoly S Abstract Small fiber neuropathy develops due to the selective damage of the thin fibers of peripheral nerves. Many common diseases can cause this condition, including diabetes, infections, autoimmune and endocrine disorders, but it can occur due to genetic alterations, as well. Eighty-five skin biopsy-proven small-fiber neuropathy cases were analyzed. Forty-one (48%) cases were idiopathic; among secondary types, hypothyreosis (9.4%), diabetes mellitus (7%), cryoglobulinemia (7%), monoclonal gammopathy with unproved significance (4.7%), Sjögren's disease (3%), and paraneoplastic neuropathy ...
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Pál E, Fülöp K, Tóth P, Deli G, Pfund Z, Janszky J, Komoly S Tags: Behav Neurol Source Type: research

Word Processing Is Faster than Picture Processing in Alzheimer's Disease.
Conclusions: Our results suggested that the processing speed in AD patients may have reduced, even if the semantic memory were preserved. These data indicated that the difference in the processing speeds by the type of stimuli (pictures, words, and nonsense syllables) may be a character of AD patients. PMID: 32399085 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2020 Category: Neurology Authors: Meguro K, Takahashi Y, Nakatsuka M, Oonuma J, Kumai K, Kasai M, Yamaguchi S Tags: Behav Neurol Source Type: research

"Olfactory Three-Needle" Enhances Spatial Learning and Memory Ability in SAMP8 Mice.
"Olfactory Three-Needle" Enhances Spatial Learning and Memory Ability in SAMP8 Mice. Behav Neurol. 2020;2020:2893289 Authors: Wang Y, Wang Q, Ren B, Guo T, Qiang J, Cao H, Gao Y, Liu Z, Gao X, Zhu B Abstract As one of the most important therapies in complementary and alternative medicine, acupuncture has been used in the treatment of Alzheimer's disease (AD). Acupuncture of "olfactory three-needle" manipulation can improve the cognitive ability of AD patients. However, the mechanism of "olfactory three-needle" in AD remains largely unknown. Here, we identified that the &q...
Source: Behavioural Neurology - May 8, 2020 Category: Neurology Authors: Wang Y, Wang Q, Ren B, Guo T, Qiang J, Cao H, Gao Y, Liu Z, Gao X, Zhu B Tags: Behav Neurol Source Type: research

Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study.
Conclusion: The preliminary results found that the patients in the action observation therapy and active control intervention groups had comparable benefits, suggesting that the 2 treatments might be used as an alternative to each other. A further large-scale study with at least 20 patients in each group to validate the study findings is needed. This trial is registered with NCT02871700. PMID: 32377266 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 8, 2020 Category: Neurology Authors: Hsieh YW, Lin YH, Zhu JD, Wu CY, Lin YP, Chen CC Tags: Behav Neurol Source Type: research

Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia.
This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer's disease are also present during the disorder's preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating b...
Source: Behavioural Neurology - May 1, 2020 Category: Neurology Authors: Meilán JJG, Martínez-Sánchez F, Martínez-Nicolás I, Llorente TE, Carro J Tags: Behav Neurol Source Type: research

Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review.
Abstract In recent years, neuroendoscopic treatment of hydrocephalus and various ventricular pathologies has become increasingly popular. It is considered by many as the first-choice treatment for the majority of these cases. However, neurocognitive complications following ventricular neuroendoscopic procedures may occur leading mostly to amnesia, which might have a grave effect on the patient's quality of life. Studies assessing neurocognitive complications after ventricular neuroendoscopic procedures are sparse. Therefore, we conducted a systematic review assessing the available literature of neurocognitive comp...
Source: Behavioural Neurology - April 18, 2020 Category: Neurology Authors: Soleman J, Guzman R Tags: Behav Neurol Source Type: research

Primary Cognitive Factors Impaired after Glioma Surgery and Associated Brain Regions.
The objective of this study was to investigate primary cognitive factors affecting not only simple cognitive tasks but also several other cognitive tasks and associated brain regions. Patients with glioma in the left (n = 33) and the right (n = 21) hemisphere participated in the study. Seven neuropsychological tasks from five cognitive domains were conducted pre- and 6 months postoperation. Factor analyses were conducted to identify "primary" common cognitive functions affecting the task performance in left and right glioma groups. Next, lesion analyses were performed using voxel-based lesion-symptom mapping (VLS...
Source: Behavioural Neurology - April 18, 2020 Category: Neurology Authors: Niki C, Kumada T, Maruyama T, Tamura M, Kawamata T, Muragaki Y Tags: Behav Neurol Source Type: research

Chronic Pain Hurts the Brain: The Pain Physician's Perspective.
a J, Nagy F PMID: 32273914 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - April 11, 2020 Category: Neurology Authors: Feher G, Szok D, Rodríguez-Saldaña J, Nagy F Tags: Behav Neurol Source Type: research

Too Real to Be Virtual: Autonomic and EEG Responses to Extreme Stress Scenarios in Virtual Reality.
In this study, 3 female participants were experiencing VR scenarios with stressful content and their activity of the autonomic nervous system and EEG were recorded. It has been discovered that virtual reality can evoke acute stress reactions accompanied by activation of the sympathetic nervous system and a decrease in the activity of the parasympathetic nervous system. The high-stress response is accompanied by a decrease in the power of the EEG, and, on the contrary, the activation of the avoidance reaction is accompanied by an increase in the power of the EEG alpha waves. Therefore, the use of stressful VR content can ca...
Source: Behavioural Neurology - April 8, 2020 Category: Neurology Authors: Fadeev KA, Smirnov AS, Zhigalova OP, Bazhina PS, Tumialis AV, Golokhvast KS Tags: Behav Neurol Source Type: research

Changes in Physiological and Pathological Behaviours Produced by Deep Microelectrode Implantation Surgery in Rats: A Temporal Analysis.
In conclusion, microelectrode implantation surgeries modified some physiological and pathological behaviours; therefore, it is important to consider this fact when it is working with animal models. PMID: 32211080 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - March 28, 2020 Category: Neurology Authors: Chiprés-Tinajero GA, Núñez-Ochoa MA, Medina-Ceja L Tags: Behav Neurol Source Type: research

Maternal Separation Early in Life Alters the Expression of Genes Npas4 and Nr1d1 in Adult Female Mice: Correlation with Social Behavior.
Abstract Early-life stress affects neuronal plasticity of the brain regions participating in the implementation of social behavior. Our previous studies have shown that brief and prolonged separation of pups from their mothers leads to enhanced social behavior in adult female mice. The goal of the present study was to characterize the expression of genes (which are engaged in synaptic plasticity) Egr1, Npas4, Arc, and Homer1 in the prefrontal cortex and dorsal hippocampus of adult female mice with a history of early-life stress. In addition, we evaluated the expression of stress-related genes: glucocorticoid and m...
Source: Behavioural Neurology - March 21, 2020 Category: Neurology Authors: Ryabushkina YA, Reshetnikov VV, Bondar NP Tags: Behav Neurol Source Type: research

Personality Factors and Subjective Cognitive Decline: The FACEHBI Cohort.
L, Boada M, Alegret M, On Behalf Of The Facehbi Study Abstract Individuals with subjective cognitive decline (SCD) have the perception of memory problems without showing impairment on standardized cognitive tests. SCD has been associated with an increased risk of developing Alzheimer's disease (AD). Neuroticism and openness personality dimensions have also been associated with SCD and AD. From the aforementioned, we aimed to ascertain whether the dimensions and traits defined by the Zuckerman-Kuhlman Personality Questionnaire (ZKPQ) differentiate between individuals with SCD and the general population (GP). A tota...
Source: Behavioural Neurology - March 11, 2020 Category: Neurology Authors: Muñoz N, Gomà-I-Freixanet M, Valero S, Rodríguez-Gómez O, Sanabria A, Pérez-Cordón A, Hernández I, Marquié M, Mir I, Martín E, Benaque A, Ruiz A, Tarraga L, Boada M, Alegret M, On Behalf Of The Facehbi Study Tags: Behav Neurol Source Type: research