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Condition: Intermittent Claudication

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Total 179 results found since Jan 2013.

Endovascular Versus Open Surgical Intervention in Patients with Takayasu's Arteritis: A Meta-analysis
Although medical treatment has advanced, surgical treatment is needed to control symptoms of Takayasu's arteritis (TA), such as angina, stroke, hypertension, or claudication. Endovascular or open surgical intervention is performed; however, there are few comparative studies on these methods. This meta-analysis and systematic review aimed to examine the outcome of surgical treatment of TA.
Source: European Journal of Vascular and Endovascular Surgery - April 2, 2018 Category: Surgery Authors: Jae Hyun Jung, Young Ho Lee, Gwan Gyu Song, Han Saem Jeong, Jae-Hoon Kim, Sung Jae Choi Tags: Review Source Type: research

Peripheral arterial disease: Treatment.
Abstract Medical management of peripheral arterial disease (PAD) patients is aimed at limb symptom relief and reducing systemic major adverse events risk. For the first purpose: exercise therapy is recommended in case of claudication; multidisciplinary evaluation for surgical options is mandatory in case of critical limb ischaemia. Reducing cardiac and stroke risk can be achieved through: statin prescription in most of the cases; antiplatelet agents in symptomatic PAD patients; cardio-vascular risk factors control. PMID: 29273182 [PubMed - as supplied by publisher]
Source: Presse Medicale - December 19, 2017 Category: General Medicine Authors: Desormais I, Aboyans V, Pesteil F, Lacroix P Tags: Presse Med Source Type: research

Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).
CONCLUSIONS : Patients with PAD are at high risk of cardiovascular events, and PCSK9 inhibition with evolocumab significantly reduced that risk with large absolute risk reductions. Moreover, lowering of low-density lipoprotein cholesterol with evolocumab reduced the risk of major adverse limb events. CLINICAL TRIAL REGISTRATION : URL: https://www.clinicaltrials.gov. Unique identifier: NCT01764633. PMID: 29133605 [PubMed - as supplied by publisher]
Source: Circulation - November 13, 2017 Category: Cardiology Authors: Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS Tags: Circulation Source Type: research

Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial
Publication date: Available online 10 November 2017 Source:The Lancet Author(s): Sonia S Anand, Jackie Bosch, John W Eikelboom, Stuart J Connolly, Rafael Diaz, Peter Widimsky, Victor Aboyans, Marco Alings, Ajay K Kakkar, Katalin Keltai, Aldo P Maggioni, Basil S Lewis, Stefan Störk, Jun Zhu, Patricio Lopez-Jaramillo, Martin O'Donnell, Patrick J Commerford, Dragos Vinereanu, Nana Pogosova, Lars Ryden, Keith A A Fox, Deepak L Bhatt, Frank Misselwitz, John D Varigos, Thomas Vanassche, Alvaro A Avezum, Edmond Chen, Kelley Branch, Darryl P Leong, Shrikant I Bangdiwala, Robert G Hart, Salim Yusuf Background Patients with periph...
Source: The Lancet - November 11, 2017 Category: General Medicine Source Type: research

Amputation Rates, Mortality, and Pre-operative Comorbidities in Patients Revascularised for Intermittent Claudication or Critical Limb Ischaemia: A Population Based Study.
CONCLUSION: The risk of amputation is particularly high during the first 6 months following revascularisation for CLI. IC patients have a benign course in terms of limb loss. Mortality in both IC and CLI patients is substantial. Revascularised CLI patients have different comorbidities from IC patients. PMID: 28797662 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 7, 2017 Category: Surgery Authors: Baubeta Fridh E, Andersson M, Thuresson M, Sigvant B, Kragsterman B, Johansson S, Hasvold P, Falkenberg M, Nordanstig J Tags: Eur J Vasc Endovasc Surg Source Type: research

Improvement of peripheral artery disease with Sildenafil and Bosentan combined therapy in a patient with limited cutaneous systemic sclerosis: A case report
We report a case of a 48-year-old Black woman, who developed severe left limb claudication and walking limitation following a left femoropopliteal bypass occlusion in 2014. She was a heavy smoker and had a history of right middle cerebral artery ischemic stroke and bilateral Raynaud phenomenon. Diagnoses: According to the American College of Rheumatology/European League Against Rheumatism-2013 criteria, diagnosis of limited cutaneous SSc was retained with macrovascular lesions. She was referred for investigation of left limb claudication on treadmill using transcutaneous oxygen pressure measurement during exercise to argu...
Source: Medicine - June 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion
Subclavian steal is a relatively common vascular phenomenon usually caused by atherosclerotic disease. While symptoms are rare, arm claudication of the ipsilateral limb is most common, with paroxysmal symptoms of vertebrobasilar insufficiency (often exercise induced) being relatively uncommon. Here we present a case of brachial artery embolism during mechanical thrombectomy for basilar artery thrombosis, secondary to subclavian steal phenomenon. This atypical and potentially irreversible complication should be considered in patients with acute ischemic stroke undergoing neurointerventional management when subclavian steal ...
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Randhawa, N., Squires, J. P., Heran, M. K. S., Mann, S. K. Tags: Electronic pages Source Type: research

Feasibility of a cardiovascular cohort in a Sub-Saharan Africa community: preliminary report of the pilot project TAHES (Tanv è Health Study) in Benin.
CONCLUSION: These preliminary results support the feasibility of establishing a cohort in Benin. It would require technical and resource support. PMID: 28498739 [PubMed - in process]
Source: Global Health Action - May 14, 2017 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

Relationship of Leukoaraiosis to Vascular Risk Factors and Lesion Type in Stroke Patients
Nonspecific periventricular white matter lucencies on computed tomograms (leukoaraiosis) were found in 49 (55%) of 89 stroke patients. We compared the vascular risk factors and the types of stroke with and without leukoaraiosis. Patients with leukoaraiosis were significantly older than those without it. The duration of hypertension was longer than those without leukoaraiosis. Mean diastolic blood pressure was associated with leukoaraiosis. No association was found with systolic blood pressure, diabetes mellitus, angina pectoris, myocardial infarction, heart failure, valvular disease and intermittent claudication. Patients ...
Source: Annals of Saudi Medicine - May 4, 2017 Category: Journals (General) Tags: ISSUE 2 Source Type: research

Walking training at the heart rate of pain threshold improves cardiovascular function and autonomic regulation in intermittent claudication: A randomized controlled trial
Conclusions In addition to increasing walking capacity, WT improved cardiovascular function and autonomic regulation in patients with IC.
Source: Journal of Science and Medicine in Sport - March 23, 2017 Category: Sports Medicine Source Type: research

Home, automated office, and conventional office blood pressure as predictors of cardiovascular risk
This study aimed to compare conventional office BP (OBP), HBP, and AOBP in order to evaluate their value in predicting CV events and deaths in hypertensives. We assessed 236 initially treatment na ïve hypertensives, examined between 2009 and 2013. The end points were any CV and non-CV event including mortality, myocardial infarction, coronary heart disease, hospitalization for heart failure, severe arrhythmia, stroke, and intermittent claudication.
Source: Journal of the American Society of Hypertension - February 2, 2017 Category: Cardiology Authors: Emmanuel A. Andreadis, Vasilios Papademetriou, Charalampia V. Geladari, George N. Kolyvas, Epameinondas T. Angelopoulos, Konstantinos N. Aronis Tags: Research Article Source Type: research

The Association between Residence Floor Level and Cardiovascular Disease: The Health and Environment in Oslo Study.
Conclusion. Floor level is positively associated with CVD, in Oslo. The best-supported explanation may be residual confounding by building height and SES. Another explanation, about the impact of atmospheric electricity, is also presented. The results underline a need to better understand the associations between residence floor level and CVD and multistory housing and CVD. PMID: 28053608 [PubMed - in process]
Source: Journal of Environmental and Public Health - January 6, 2017 Category: Environmental Health Tags: J Environ Public Health Source Type: research

Peripheral Revascularization in Patients With Peripheral Artery Disease With Vorapaxar: Insights From the TRA 2{degrees}P-TIMI 50 Trial
Conclusions Vorapaxar reduces peripheral revascularization in patients with PAD. This benefit of vorapaxar is directionally consistent across type of procedure and indication. (Trial to Assess the Effects of Vorapaxar [SCH 530348; MK-5348] in Preventing Heart Attack and Stroke in Patients With Atherosclerosis [TRA 2°P - TIMI 50] [P04737]; NCT00526474)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 23, 2016 Category: Cardiology Authors: Bonaca, M. P., Creager, M. A., Olin, J., Scirica, B. M., Gilchrist, I. C., Murphy, S. A., Goodrich, E. L., Braunwald, E., Morrow, D. A. Tags: Peripheral Source Type: research

Short stature in men is associated with subclinical peripheral arterial disease.
CONCLUSIONS: Short stature in men is associated with subclinical PAD and lower ABI values. PMID: 27598046 [PubMed - as supplied by publisher]
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 5, 2016 Category: Surgery Authors: Heikkilä A, Venermo M, Kautiainen H, Arnio P, Korhonen P Tags: Vasa Source Type: research

Scallops, fenestrations, CHIMPS, and other monkey business
The coverage of branch vessels during thoracic endovascular aortic repair (TEVAR) with resultant end-organ ischemia is a limitation of endograft technology. Although coverage of the left subclavian artery (LSA) initially was thought to be safe (zone 2 TEVAR), experience has shown that LSA ischemia comes at the cost of permanent stroke and spinal cord injury and reversible complications of arm claudication and vertebrobasilar ischemia. Preserving flow to the LSA in the acute setting remains a clinical dilemma because the emergency nature of the procedure often precludes time-consuming efforts to preserve LSA flow.
Source: The Journal of Thoracic and Cardiovascular Surgery - July 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: S. Chris Malaisrie Tags: Editorial commentary Source Type: research