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Condition: Intermittent Claudication
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Total 179 results found since Jan 2013.
Peripheral Vascular Disease and Carotid Artery Disease Are Associated with Decreased Bile Acid Excretion
This study investigated BAE in patients with peripheral vascular disease (PVD) and carotid artery disease (CA) and those without these diseases, compared to patients with CAD, stroke, or no evidence of atherosclerosis. Patients with complaints of chest pain-suspected CAD, syncope, stroke/TIA, severe headache, intermittent claudication, or falls were enrolled. All received a 4-day standard diet with 490 mg of cholesterol and internal standard copper thiocyanate. Fecal BAE was measured using gas-liquid chromatography. One hundred and three patients, sixty-eight (66%) men and thirty-five women (34%), mean age range 60.9 ± 8....
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Lior Charach Gideon Charach Eli Karniel Leonid Galin Dorin Bar Ziv Lior Grossman Irit Kaye Itamar Grosskopf Source Type: research
Inflammation and immunomodulatory therapies influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis
CONCLUSION: ABCA1-CEC associated with decreased atherosclerosis in patients with below-median baseline and time-averaged CRP and bDMARD use. Conversely, ABCA1-CEC associated with increased plaque in those with higher CRP, corticosteroid users, methotrexate nonusers, and bDMARD nonusers. While in well-treated and controlled disease ABCA1-CEC appears atheroprotective, in uncontrolled RA its action may be masked or fail to counteract the inflammation-driven proatherogenic state.PMID:37520890 | PMC:PMC10371792 | DOI:10.1016/j.jtauto.2023.100209
Source: Atherosclerosis - July 31, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Peripheral artery disease: Update on etiology, pathophysiology, diagnosis and treatment
Med Clin (Barc). 2023 Jul 28:S0025-7753(23)00361-5. doi: 10.1016/j.medcli.2023.06.005. Online ahead of print.ABSTRACTPeripheral artery disease (PAD) is a condition related to atherosclerosis affecting >200 million people worldwide, and it increases cardiovascular morbidity (mainly from myocardial infarction and stroke) and mortality. Indeed, PAD patients are classified as patients at very high cardiovascular risk. The most common manifestation of PAD is intermittent claudication, which is associated with reduced mobility and leg pain. Nevertheless, asymptomatic PAD is the most frequent form of PAD worldwide; therefore, ...
Source: Medicina Clinica - July 30, 2023 Category: General Medicine Authors: Dar ío Mandaglio-Collados Francisco Mar ín Jos é Miguel Rivera-Caravaca Source Type: research
Statins influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis
CONCLUSION: In patients with RA, higher ABCA1-CEC may reflect a proatherogenic state, associated with enhanced cardiovascular risk. Statin use may unmask the protective impact of ABCA1-mediated cholesterol efflux on plaque formation, progression and cardiovascular risk.PMID:37484708 | PMC:PMC10362327 | DOI:10.1016/j.jtauto.2023.100206
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Probabilistic graphical modelling using Bayesian networks for predicting clinical outcome after posterior decompression in patients with degenerative cervical myelopathy
CONCLUSIONS: The causal predictors of surgical outcome for DCM were sex, dementia and PreJOA score. Therefore, PGM may be a useful personalized medicine tool for predicting the outcome of patients with DCM.PMID:37435966 | DOI:10.1080/07853890.2023.2232999
Source: Annals of Medicine - July 12, 2023 Category: Internal Medicine Authors: Dong Ah Shin Sun-Ho Lee Sohee Oh Changwon Yoo Hee-Jin Yang Ikchan Jeon Sung Bae Park Source Type: research
A rare case of positional vertebrobasilar ischemia with the retrograde flow of the vertebral artery
J Surg Case Rep. 2023 May 12;2023(5):rjad222. doi: 10.1093/jscr/rjad222. eCollection 2023 May.ABSTRACTPositional vertebrobasilar ischemia, also known as Bow hunter stroke, is typically caused by mechanical compression of the vertebral artery (VA). On the other hand, subclavian steal syndrome is incidentally detected by vertigo, syncope or loss of consciousness due to the steal phenomenon. A 61-year-old man suffered from near syncope when he turned his head to the left side. Although asymmetric arm blood pressure of the right dominant was observed, arm claudication was not detected. Computed tomographic angiography and magn...
Source: Hand Surgery - May 16, 2023 Category: Surgery Authors: Toshihiro Kawahira Hiroki Morimoto Source Type: research
The association of calcium channel blocker with risk of adverse limb events in patients with chronic limb-threatening ischemia after endovascular treatment
This study highlights the necessity of future studies regarding CCB.Clinical Trial Registration: URL:https://www.umin.ac.jp; Unique identifiers: UMIN000015100.
Source: Cardiovascular Intervention and Therapeutics - April 3, 2023 Category: Cardiology Source Type: research
Differences in major limb outcomes by indication for lower extremity endovascular revascularization in patients receiving hemodialysis
This study is to determine whether indication of PAD has a distinct impact on major adverse cardiovascular and cerebrovascular events (MACCE) and limb events in patients receiving hemodialysis. The current study included 2321 prospectively enrolled patients from the Tokyo taMA peripheral vascular intervention research ComraDE registry (UMIN-CTR no. UMIN000015100) between September 2014 and December 2016. Out of the enrolled patients, 1644 were not receiving hemodialysis (non-HD patients) and 603 were receiving hemodialysis (HD patients). A composite of all-cause death, myocardial infarction, and stroke events defined as MA...
Source: Heart and Vessels - April 1, 2023 Category: Cardiology Source Type: research
ATP-binding cassette G1 membrane transporter-mediated cholesterol efflux capacity influences coronary atherosclerosis and cardiovascular risk in Rheumatoid Arthritis
CONCLUSION: ABCG1-CEC inversely associated with plaque burden and vulnerability, and plaque progression conditionally on cumulative inflammation and corticosteroid dose. ABCG1-CEC inversely associated with events specifically in patients with noncalcified plaques, lower inflammation and in prednisone users.PMID:36996698 | DOI:10.1016/j.jaut.2023.103029
Source: Atherosclerosis - March 30, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Differences in major limb outcomes by indication for lower extremity endovascular revascularization in patients receiving hemodialysis
This study is to determine whether indication of PAD has a distinct impact on major adverse cardiovascular and cerebrovascular events (MACCE) and limb events in patients receiving hemodialysis. The current study included 2321 prospectively enrolled patients from the Tokyo taMA peripheral vascular intervention research ComraDE registry (UMIN-CTR no. UMIN000015100) between September 2014 and December 2016. Out of the enrolled patients, 1644 were not receiving hemodialysis (non-HD patients) and 603 were receiving hemodialysis (HD patients). A composite of all-cause death, myocardial infarction, and stroke events defined as MA...
Source: Heart and Vessels - March 6, 2023 Category: Cardiology Source Type: research
Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
CONCLUSION: Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.PMID:36819979 | PMC:PMC9938786 | DOI:10.1155/2023/7989712
Source: Case Reports in Psychiatry - February 23, 2023 Category: Psychiatry Authors: Heidi Madeleine Latvala Solveig Kl æbo Reitan Arne Einar Vaaler Source Type: research
