Effect of the recording condition on the quality of a single-lead electrocardiogram
This study aimed to evaluate the quality of single-lead ECG in healthy subjects under various conditions (body positions and motions) and in patients with arrhythmias, to estimate requirements for automatic analysis, and to identify a way to improve ECG quality by changing the type and placement of electrodes. A single-lead ECG transmitter was placed on the sternum with a pair of electrodes, and ECG was simultaneously recorded with a conventional Holter ECG in 12 healthy subjects under various conditions and 35 patients with arrhythmias. Subjects with arrhythmias were divided into sinus rhythm (SR) and atrial fibrillation ...
Source: Heart and Vessels - December 2, 2021 Category: Cardiology Source Type: research

Association between testosterone and lipid profiles under statin therapy and its clinical impact on the cardiovascular event risk
AbstractStatin therapy may decrease the levels of serum steroid hormones, including testosterone and cortisol, accompanied by lowering low-density lipoprotein cholesterol (LDL-C) levels, which remains to be investigated. The aim of this study is to examine the association between steroid hormones and lipids under statin therapy and its clinical impact on the cardiovascular event risk from a viewpoint of steroid hormone metabolism. Using a population dataset extracted from the standard versus intEnsive statin therapy for hyper-cholesteroleMic Patients with diAbetic retinopaTHY (EMPATHY) study, we analyzed the correlation be...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Oxidative stress-responsive apoptosis-inducing protein in patients with heterozygous familial hypercholesterolemia
In this study, we investigated the role of ORAIP in patients with heterozygous familial hypercholesterolemia (HeFH), a leading cause of premature cardiovascular disease. We analyzed plasma ORAIP and oxidized low-density lipoprotei n (oxLDL) levels in 60 patients with HeFH (60% male, 57.0 ± 13.6 years of age) and 20 patients with LDL-C hypercholesterolemia (DL, 85% male, 64.1 ± 13.3 years of age). The coronary artery atherosclerosis from the patients with HeFH who had a coronary artery bypass graft was investigated b y double immunostaining. The plasma ORAIP levels in the pati...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Impact of heart failure severity on bone mineral density among older patients with heart failure
AbstractThe study aimed to identify factors related to bone mineral density (BMD) among older patients with heart failure (HF). A total of 70 consecutive patients with HF aged 65  years or older who were admitted to an acute hospital due to worsening condition were enrolled before discharge. BMD of the femoral neck was evaluated using the DEXA method. Physical function, as well as echocardiographic and laboratory findings including biomarker of HF severity were collected. B ivariate and multiple regression analyses were employed to determine the association between BMD and the clinical variables. Bivariate analysis de...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Impact of homocysteine levels on mortality risk in patients with chronic limb-threatening ischemia undergoing revascularization
AbstractThe current study aimed to reveal the clinical impact of plasma homocysteine levels in chronic limb-threatening ischemia (CLTI) patients undergoing revascularization. This was a sub-analysis of a prospective multicenter registry of CLTI patients, named the Surgical reconstruction versus Peripheral INtervention in pAtients with critical limb isCHemia (SPINACH) study. The current analysis included 192 non-dialysis-dependent CLTI patients who underwent revascularization for CLTI, and whose plasma homocysteine levels at baseline were available. The association of clinical characteristics with  homocysteine levels&...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Structural heart disease, not the right ventricular pacing site, determines the QRS duration during right ventricular pacing
AbstractRight ventricular (RV) pacing causes changes in the heart ’s electrical and mechanical activation patterns. The QRS duration is a useful surrogate marker of electrical dyssynchrony; a longer QRS duration during RV pacing indicates poor prognosis. However, the mechanisms underlying a longer QRS duration during RV pacing remain unclear; hence, we investiga ted factors predicting QRS prolongation during RV pacing. We enrolled 211 patients who underwent catheter ablation for supraventricular tachyarrhythmia and showed no bundle branch block. Three-dimensional mapping for the QRS duration during RV pacing from the...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Left atrial dimension and ischemic stroke in patients with and without atrial fibrillation
AbstractThe incidence of ischemic stroke (IS) increases in patients with enlarged left atrium (LA) irrespective of whether or not the existence of atrial fibrillation (AF). In such situation, it is unclear whether the impact of LA on incidence of IS still significant in young, non-AF patients with enlarged LA who are primarily unconcerned on anticoagulation therapy. The study population consisted of 18,511 consecutive patients not receiving oral anticoagulants and undergoing echocardiography with measurement of LAD at baseline. The incidence rate of ischemic stroke was calculated in 3 groups according to left atrial dimension (LAD;  
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Prognostic significance of the get with the guidelines-heart failure (GWTG-HF) risk score in patients undergoing trans-catheter tricuspid valve repair (TTVR)
AbstractThe Get-With-The-Guidelines-Heart-Failure (GWTG-HF) score is a risk assessment tool to predict mortality in patients with heart-failure (HF). We aimed to evaluate the GWTG-HF score for risk stratification in HF patients with tricuspid regurgitation undergoing trans-catheter tricuspid valve repair (TTVR). In total, 181 patients who underwent TTVR via edge-to-edge repair (86%) or annuloplasty (14%) were enrolled. Patients were categorized into a low- ( ≤ 43 points), intermediate- (44–53 points) and high-risk score groups (≥ 54 points). TTVR led to an improvement of TR (p 
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

TGF- β1 polymorphism increases the risk of bleeding complications in patients on oral anticoagulant after cardiac valve replacement
This study aimed to determine if there is an association between transforming growth factor beta-1 (TGF-β1) polymorphisms and bleeding complications in patients who maintain international normalized ratios (INRs) of 2.0–3.0 with warfarin therapy after cardiac valve replacement. Eleven single nucleotide polymorphis (SNPs) of TGF-β1 (rs1800469, rs2241718, rs4803455, rs2241717, r s2241716, rs2241715, rs2241714, rs11083616, rs2317130, rs747857, and rs1982073) were analyzed. Univariate and multivariable analyses were conducted to evaluate the associations between genetic polymorphisms and bleeding risk. Att...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Frequency, predictors, and effect of the slow-flow phenomenon after drug-coated balloon angioplasty for femoropopliteal lesions
This study aimed to investigate the frequency, predictors, and effect of the slow-flow phenomenon following DCB angioplasty for FP lesions. This single-center, retrospective, observational study analyzed 88 FP lesions treated by DCB angioplasty between April 2018 and July 2019. Patients were divided into the slow-flow group (n = 7) and non-slow-flow group (n = 81) and were analyzed. The primary endpoint was primary patency at 6 months. The slow-flow phenomenon was observed in seven cases (8.0%). The slow-flow group had higher incidence rates of critical limb ischemia (CLI) (71% vs. 25%,p 
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Body composition and mortality in patients undergoing endovascular treatment for peripheral artery disease
This study evaluated the relationships between the lean body mass index (LBMI), body fat % (BF%), and mortality and major amputation rate in patients with PAD. We evaluated 320 patients with PAD after endovascular treatment (EVT) enrolled from August 2015 to July 2016 and divided them into low and high LBMI and BF% groups based on their median values (17.47  kg/m2 and 22.07%, respectively). We assessed 3-year mortality and major amputation for the following patient groups: Low LBMI/Low BF%, Low LBMI/High BF%, High LBMI/Low BF%, and High LBMI/High BF%. During the median 3.1-year follow-up period, 70 (21.9%) patients di...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Heart failure with mid-range ejection fraction and the effect of β-blockers after acute myocardial infarction
AbstractThere is currently an ongoing debate about the ‘grey area’ of heart failure with mid-range ejection fraction (HFmrEF). We evaluated characteristics, prognosis, and the effect of β-blockers on clinical outcomes in patients with HFmrEF after acute myocardial infarction (AMI). We included a total of 10,785 patients and divided them into three groups: EF 40–49% (HFmrEF;n = 2717; reference); EF 
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Sex-specific relationship between abdominal obesity and new-onset atrial fibrillation in the general Japanese population
This study aimed to investigate the sex-specific relationship between abdominal obesity and new-onset AF. This retrospective study evaluated the annual health checkup data of 67,379 adults (33,562 males; age, 54  ± 10 years) without baseline AF from April 2008 to March 2016. Participants were grouped according to waist circumference (WC): large-WC group (males, ≥ 85 cm; females, ≥ 90 cm) and normal-WC group. Logistic regression analyses were performed to determine the strength of the ass ociation between abdominal obesity and new-onset AF, overall and se...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy
AbstractThe mortality of patients with non-ischemic dilated cardiomyopathy (NIDCM) remains substantial. We evaluated gene expression levels of myocardin, an early cardiac gene, in the peripheral blood cells of NIDCM patients as a prognostic biomarker in their long-term outcome and mortality from congestive HF (CHF). We retrospectively analyzed 101 consecutives optimally treated NIDCM patients of Cretan origin who were enrolled from the HF clinic of our hospital from November 2005 to December 2008. Our patient data were either taken from their medical files or recorded during visits to the HF unit or hospitalizations. Follo...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Coronary artery spasm-induced acute myocardial infarction in patients with myocardial infarction with non-obstructive coronary arteries
AbstractCoronary artery spasm-induced acute myocardial infarction (CASIAMI) is one of the etiologies of myocardial infarction with non-obstructive coronary arteries (MINOCA). We retrospectively analyzed the incidence and clinical characteristics of Japanese patients with CASIAMI and non-obstructive coronary arteries. We experienced 62 patients with MINOCA (10 thrombosis, 7 unknown causes, and 45 CASIAMI) among 991 patients with suspected AMI. Pharmacological spasm provocation testing was performed in 37 patients. CASIAMI without obstructive coronary arteries was found in 4.5% of patients with suspected AMI and was observed...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Comparison of long-term mortality in patients who underwent transcatheter aortic valve replacement with or without anti-atherosclerotic therapy
This study aimed to investigate whether anti-atherosclerotic therapy (AT), defined as the simultaneous use of antiplatelet agents, statins, and renin aldosterone system inhibitors, had long-term clinical benefits for patients who underwent transcatheter aortic valve replacement (TAVR). Between October 2013 and May 2017, 2518 patients  (31% men; median age, 85 years) who underwent TAVR in 14 Japanese centers were divided into two groups: patients who were prescribed anti-atherosclerotic therapy (AT,n = 567) and patients who were not (no AT,n = 1951). The median follow-up period for this...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

N-terminal pro-brain natriuretic peptide and coronary collateral formation in patients undergoing primary percutaneous coronary intervention
AbstractThere is insufficient information on the relationship between the N-terminal pro-brain natriuretic peptide (NT-proBNP) level and collateral circulation (CC) formation after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction. We analyzed 857 patients who underwent primary PCI. The serum NT-proBNP levels were measured on the day of admission, and the CC was scored according to Rentrop ’s classification. Log-transformed NT-proBNP levels were significantly higher in patients with good CC compared to those with poor CC (6.13 ± 2.01 ...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Relationship of end-tidal oxygen partial pressure to the determinants of anaerobic threshold in post-myocardial infarction patients
AbstractThe anaerobic threshold (AT), obtained during cardiopulmonary exercise testing (CPET), is an important prognostic measure and can be used to develop an exercise prescription in patients after a myocardial infarction (post-MI). The purpose of this study was to examine the central and peripheral determinants of AT in post-MI patients end-tidal oxygen partial pressure (PETO2) measures. We performed cardiopulmonary exercise testing (CPET) on 148 consecutively enrolled post-MI patients to determine PETO2 measured at the AT (AT PETO2) and ΔPETO2 (difference between resting PETO2 and AT PETO2). We subsequently inves...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Incidental findings on computed tomography for preoperative assessment before transcatheter aortic valve implantation in Japanese patients
AbstractExtra-cardiovascular incidental findings (IFs) on preoperative computed tomography (CT) are frequently observed in transcatheter aortic valve implantation (TAVI) candidates. However, the backgrounds of TAVI candidates and comorbidities differ based on the race and/or country, and data on IFs in a specific population are not always applicable to another. The aim of this study was to assess the prevalence, type, and clinical impact of IFs in Japanese TAVI candidates. This was a retrospective, single-center, observational study. CT reports of 257 TAVI candidates were reviewed, and IFs were classified as (a) insignific...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Enhancement patterns detected by multidetector computed tomography are associated with the long-term prognosis of patients with acute myocardial infarction
AbstractThe present study investigated the clinical value of myocardial contrast-delayed enhancement (DE) with multidetector computed tomography (MDCT) without iodine re-injection immediately after primary percutaneous coronary intervention (PCI) for predicting future cardiovascular events after acute myocardial infarction (AMI). We performed a prospective study in which 263 consecutive patients with first AMI successfully treated with primary PCI were enrolled. Sixty-four-slice MDCT without the re-injection of contrast medium was performed immediately after PCI. Myocardial DE was considered to be transmural when involving...
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Acknowledgement to reviewers
(Source: Heart and Vessels)
Source: Heart and Vessels - November 3, 2021 Category: Cardiology Source Type: research

Oxidative stress-responsive apoptosis-inducing protein in patients with heterozygous familial hypercholesterolemia
In this study, we investigated the role of ORAIP in patients with heterozygous familial hypercholesterolemia (HeFH), a leading cause of premature cardiovascular disease. We analyzed plasma ORAIP and oxidized low-density lipoprotei n (oxLDL) levels in 60 patients with HeFH (60% male, 57.0 ± 13.6 years of age) and 20 patients with LDL-C hypercholesterolemia (DL, 85% male, 64.1 ± 13.3 years of age). The coronary artery atherosclerosis from the patients with HeFH who had a coronary artery bypass graft was investigated b y double immunostaining. The plasma ORAIP levels in the pati...
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

Impact of heart failure severity on bone mineral density among older patients with heart failure
AbstractThe study aimed to identify factors related to bone mineral density (BMD) among older patients with heart failure (HF). A total of 70 consecutive patients with HF aged 65  years or older who were admitted to an acute hospital due to worsening condition were enrolled before discharge. BMD of the femoral neck was evaluated using the DEXA method. Physical function, as well as echocardiographic and laboratory findings including biomarker of HF severity were collected. B ivariate and multiple regression analyses were employed to determine the association between BMD and the clinical variables. Bivariate analysis de...
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

Impact of homocysteine levels on mortality risk in patients with chronic limb-threatening ischemia undergoing revascularization
AbstractThe current study aimed to reveal the clinical impact of plasma homocysteine levels in chronic limb-threatening ischemia (CLTI) patients undergoing revascularization. This was a sub-analysis of a prospective multicenter registry of CLTI patients, named the Surgical reconstruction versus Peripheral INtervention in pAtients with critical limb isCHemia (SPINACH) study. The current analysis included 192 non-dialysis-dependent CLTI patients who underwent revascularization for CLTI, and whose plasma homocysteine levels at baseline were available. The association of clinical characteristics with  homocysteine levels&...
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

TGF- β1 polymorphism increases the risk of bleeding complications in patients on oral anticoagulant after cardiac valve replacement
This study aimed to determine if there is an association between transforming growth factor beta-1 (TGF-β1) polymorphisms and bleeding complications in patients who maintain international normalized ratios (INRs) of 2.0–3.0 with warfarin therapy after cardiac valve replacement. Eleven single nucleotide polymorphis (SNPs) of TGF-β1 (rs1800469, rs2241718, rs4803455, rs2241717, r s2241716, rs2241715, rs2241714, rs11083616, rs2317130, rs747857, and rs1982073) were analyzed. Univariate and multivariable analyses were conducted to evaluate the associations between genetic polymorphisms and bleeding risk. Att...
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

Heart failure with mid-range ejection fraction and the effect of β-blockers after acute myocardial infarction
AbstractThere is currently an ongoing debate about the ‘grey area’ of heart failure with mid-range ejection fraction (HFmrEF). We evaluated characteristics, prognosis, and the effect of β-blockers on clinical outcomes in patients with HFmrEF after acute myocardial infarction (AMI). We included a total of 10,785 patients and divided them into three groups: EF 40–49% (HFmrEF;n = 2717; reference); EF 
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

Acknowledgement to reviewers
(Source: Heart and Vessels)
Source: Heart and Vessels - October 30, 2021 Category: Cardiology Source Type: research

Modified ablation index: a novel determinant of a successful first-pass left atrial posterior wall isolation
This study aimed to evaluate the performance of a modified ablation index (AI) (AI/bipolar voltage along the ablation line) for predicting a durable LAPWI. The study included 55 consecutive patients, aged 65  ± 11 years, who underwent an electroanatomic mapping-guided LAPWI of AF. The association between the gaps (first-pass LAPWI failure and/or acute LAPW reconnections), voltage amplitude along the roof and floor lines, and thickness of the LAPW was investigated. Gaps occurred in 22 patients (40% ) and in 26 (8%) of the 330 line segments. Gaps were associated with a relatively high bipolar voltag...
Source: Heart and Vessels - October 28, 2021 Category: Cardiology Source Type: research

Identification of high priority focal activations in persistent atrial fibrillation using a novel mapping strategy
In conclusion, DFAs may play an important role in AF maintenance and could be an attractive therapeutic target for AF. (Source: Heart and Vessels)
Source: Heart and Vessels - October 27, 2021 Category: Cardiology Source Type: research

Dabigatran plasma concentration indicated the risk of patients with non-valvular atrial fibrillation
This study aimed to evaluate the variability of dabigatran plasma concentration and the association with clinical events in Chinese patients treated with dabigatran etexilate (DE) for non-valvular atrial fibrillation (NVAF). The steady-state concentration of dabigatran (the active metabolite of DE) was determined at trough and peak. The effect of dabigatran concentration variability and related factors on clinical outcomes were explored. Data from 86 patients receiving a fixed dose of 110  mg showed that dabigatran trough concentration varied remarkably. Age, BMI and history of heart failure were identified as importa...
Source: Heart and Vessels - October 25, 2021 Category: Cardiology Source Type: research

Early diastolic mitral regurgitation in left ventricular aneurysm
This study aimed to explore the mechanism underlying early diastolic mitral regurgitation (EDMR) in patients with left ventricular (LV) aneurysms after anterior myocardial infarction (AMI) by assessing the intraventricular pressure difference using vector flow mapping. We enrolled 23 consecutive patients with LV aneurysms (with and without EDMR) and 15 healthy men as controls. In the control group, LV suction began from the apex during early diastole. In contrast, the blood that pooled in the apical aneurysm during systole generated a relatively higher pressure at the apex than at the basal LV during early diastole; conseq...
Source: Heart and Vessels - October 24, 2021 Category: Cardiology Source Type: research

Characteristics of patients with atrial flutter and spontaneous 1:1 atrioventricular conduction with and without anti-arrhythmic drug treatment
AbstractAtrial flutter (AFL) is a large reentrant circuit located in the right atrium. Anti-arrhythmic drugs (AADs) can provoke AFL with 1:1 atrioventricular conduction (AVC) to cause hemodynamic collapse. We elucidated the characteristics of patients with AFL exhibiting spontaneous 1:1 AVC. Fifteen patients (1:1 AFL group; 11 males, 52.4  ± 13.7 years old) who documented AFL with 1:1 AVC were enrolled and compared to 153 patients without 1:1 AVC (Control group; 137 males, 68.9 ± 11.2 years old). AFL cycle length during maximum AVC was significantly longer in the 1:1 AFL ...
Source: Heart and Vessels - October 22, 2021 Category: Cardiology Source Type: research

Delayed stenosis regression after drug-coated balloon angioplasty for femoropopliteal artery lesions
This study was carried out to determine the possibility of and the relevant factors of delayed stenosis regression after drug-coated balloon (DCB) angioplasty for femoropopliteal (FP) artery lesions. A total 105 de novo FP lesions were finalized with DCB angioplasty in our institute between May 2018 and June 2020. Among them, cases in which residual stenosis was detected by duplex ultrasonography (DUS) after the procedure were included in this study. Significant stenosis was defined as peak systolic velocity ratio  ≥ 2.4 by DUS. Follow-up DUS was routinely performed 6 months after the procedure, and w...
Source: Heart and Vessels - October 21, 2021 Category: Cardiology Source Type: research

Publisher Correction to: Safety, effectiveness and mid-term follow-up in 136 consecutive patients with moderate to severely calcified lesions undergoing phoenix atherectomy
(Source: Heart and Vessels)
Source: Heart and Vessels - October 20, 2021 Category: Cardiology Source Type: research

Prognostic value of an echocardiographic index reflecting right ventricular operating stiffness in patients with heart failure
ConclusionA completely noninvasive index of RV operating stiffness, PRPGDAC/TAPMAC, was useful for predicting prognoses in patients with HF, and it showed an incremental prognostic value over RV systolic function. (Source: Heart and Vessels)
Source: Heart and Vessels - October 16, 2021 Category: Cardiology Source Type: research

Clinical features and long-term prognosis of patients with congestive heart failure taking tolvaptan: a comparison of patients with preserved and reduced left ventricular ejection fraction
This study evaluated the long-term prognosis of patients administered TLV for  >  1 year among patients who had HF with preserved ejection fraction (HFpEF) and those who had HF with reduced ejection fraction (HFrEF). Overall, 591 consecutive patients were admitted to our hospital and administered TLV for HF between 2011 and 2018. We retrospectively enrolled 147 patients who w ere administered TLV for >  1 year. We divided them into the HFpEF group (n = 77, 52.4%) and the HFrEF group (n = 70; 47.6%). Their clinical backgrounds and long-term prognosis we...
Source: Heart and Vessels - October 14, 2021 Category: Cardiology Source Type: research

Disparate effects of ankle-brachial index on mortality in the ‘very old’ and ‘younger old’ populations-the PolSenior survey
AbstractTo assess the relationship between ankle-brachial index (ABI) and up to 10-year mortality in older individuals below and above the age of 80  years. In a multicenter survey of health status in the community dwelling subjects aged 55–59 and 65 + years in Poland, we assessed baseline medical history including risk-factors. We measured ABI, and serum creatinine, cholesterol, NT-proBNP, and interleukin-6 (IL-6) concentrations. We asse ssed mortality based on public registry. Between 2009 and 2019, 27.3% of 561 participants 
Source: Heart and Vessels - October 13, 2021 Category: Cardiology Source Type: research

Comparing pharmacotherapy in MINOCA versus medically managed obstructive acute coronary syndrome
This study uniquely compares the management and outcomes of MINOCA patients with a medically managed obstructive ACS (M-ACS) population. We retrospectively analysed registry data for consecutive patients admitted to the Gold Coast University Hospital with ACS requiring coronary angiography and identified patients with MINOCA and M-ACS. Baseline characteristics, pharmacological therapy and in-hospital outcomes were compared. In hospital outcomes were composite NACE, heart failure, stroke and major bleeding. Multivariate regression analysis was also performed to identify independent predictors of MINOCA. Multivariate regress...
Source: Heart and Vessels - October 10, 2021 Category: Cardiology Source Type: research

Catheter-related thrombosis after cardiac surgery in patients with both central venous and pulmonary artery catheters inserted into the right internal jugular vein: a single-center, prospective, observational study
In conclusion, patients who underwent cardiovascular surgery and using both CVC and PAC h ad a high incidence of CRT. Avoiding unnecessary PAC placement and early removal of catheters in patients at high risk of developing CRT may prevent the development of CRT. (Source: Heart and Vessels)
Source: Heart and Vessels - October 7, 2021 Category: Cardiology Source Type: research

Dual-energy CT plaque characteristics of post mortem thin-cap fibroatheroma in comparison to infarct-related culprit lesions
AbstractImprovement of non-invasive identification of high-risk plaque may increase the preventive options of acute coronary syndrome. To describe the characteristics of thin-cap fibroatheroma (TCFA) in a post mortem model in comparison to characteristics of culprit lesions in patients with non-ST-elevation-myocardial-infarction (NSTEMI) using the dual energy computed tomography (DECT). Three post mortem hearts were prepared with iodine-contrast, inserted in a Kyoto phantom and scanned by DECT. Six TCFA were identified using histopathological analysis (cap thickness    10% of the plaque area). In the NSTEMI g...
Source: Heart and Vessels - October 4, 2021 Category: Cardiology Source Type: research

Prognostic value of infarct-related-lead Tpeak –Tend/QT ratio in patients with ST-segment elevation myocardial infarction
AbstractTpeak –Tend/QT ratio (Tp–e/QT) in patients with ST-segment elevation myocardial infarction (STEMI) is reportedly associated with major adverse cardiac events (MACEs). However, Tp–e/QT measurement methods are controversial, and few studies have clarified the effect of different Tp–e/QT measures on prognosis. Our study is the first to investigate the advantages of the Tp–e/QT measured by infarct-related-lead method in predicting MACEs during hospitalization and long-term mortality in patients with STEMI. A total of 427 STEMI patients undergoing primary percutaneous coronary intervention ...
Source: Heart and Vessels - October 2, 2021 Category: Cardiology Source Type: research

Pulmonary vein stenosis after HotBalloon pulmonary vein isolation of paroxysmal atrial fibrillation
AbstractHotBalloon-based pulmonary vein isolation (HBPVI) has yielded encouraging clinical results in the treatment of paroxysmal atrial fibrillation (PAF). However, pulmonary vein (PV) stenosis remains a concern. The influence of longer application duration on PV stenosis has not yet been systematically evaluated. All patients who underwent first HBPVI of PAF with pre- and post-ablation computed tomography (CT) were included. We used single-shot technique with application duration of 180  s in the RSPV, 180–240 s in the LSPV, and 120 s in the lower PV procedures. PV stenosis was analyzed using CT and ...
Source: Heart and Vessels - September 30, 2021 Category: Cardiology Source Type: research

Impact of optimal heart rate on left ventricular reverse remodeling and functional improvement in patients with systolic heart failure
AbstractHeart rate modulation therapy using ivabradine reduces mortality and morbidity in patients with systolic heart failure, whereas too reduced heart rate seems to worsen the clinical outcome. The optimal heart rate during heart rate modulation therapy remains unknown. Consecutive patients with left ventricular ejection fraction  
Source: Heart and Vessels - September 30, 2021 Category: Cardiology Source Type: research

Clinical evaluation of retrievable inferior vena cava filters for the prevention of pulmonary thromboembolism
This study retrospectively investigated the acute PTE relapse prevention rate, IVCF retrieval attempt rate, retrieval success rate, and long-term prognosis of 197 patients who underwent r-IVCF insertion at our hospital between 2010 and 2018.ResultsSubjects had a mean age of 68  years and a male-to-female ratio of 1:1. After r-IVCF insertion, the acute PTE prevention rate was 99.5%. The r-IVCF retrieval rate was 55% (108 patients), with a success rate of 99% (107 patients). r-IVCF retrieval was not attempted in 89 cases due to advanced cancer or poor prognosis (41%), loss to follow-up (32%), and long-term indwelling IV...
Source: Heart and Vessels - September 30, 2021 Category: Cardiology Source Type: research

Circulating TNFrII levels predict incidence of ischemic heart disease and total mortality, independently of intima media thickness and pulse wave velocity in male with type 2 diabetes
AbstractNew and clinically useful markers of cardiovascular risk are of great importance in patients with type 2 diabetes since cardiovascular disease is a major cause of death in these patients. We analyzed inflammatory markers and other risk factors for heart disease in 761 patients who participated in the CARDIPP-study, Cardiovascular Risk factors in Patients with Diabetes —a Prospective study in Primary care. All participants had type 2 diabetes and were 55–66 years old at recruitment during the years 2005–2008. Patients were followed for incidence of stroke, myocardial infarction, or death from ...
Source: Heart and Vessels - August 21, 2021 Category: Cardiology Source Type: research

Impact of left ventricular ejection fraction and preoperative hemoglobin level on perioperative adverse cardiovascular events in noncardiac surgery
AbstractThe prediction of a perioperative adverse cardiovascular event (PACE) is an important clinical issue in the medical management of patients undergoing noncardiac surgery. Although several predictors have been reported, simpler and more practical predictors of PACE have been needed. The aim of this study was to investigate the predictors of PACE in noncardiac surgery. We retrospectively analyzed 723 patients who were scheduled for elective noncardiac surgery and underwent preoperative examinations including 12-lead electrocardiography, transthoracic echocardiography, and blood test. PACE was defined as cardiac death,...
Source: Heart and Vessels - August 9, 2021 Category: Cardiology Source Type: research

Post-ablation left atrial function impacts long-term recurrence of atrial fibrillation after ablation
AbstractLeft atrial (LA) function can help predict various cardiovascular events. Catheter ablation for atrial fibrillation (AF) modifies baseline LA function through the maintenance of sinus rhythm and myocardial injury. We investigated the impact of post-ablation LA function on recurrence of AF after ablation and identified the predictors of reduced post-ablation LA function. A total of 616 patients who underwent AF ablation (paroxysmal,N = 310; non-paroxysmal,N = 306) were retrospectively examined with cardiac computed tomography at baseline and 3 months after the final ablation procedur...
Source: Heart and Vessels - August 3, 2021 Category: Cardiology Source Type: research

Ability of soluble ST2 to predict left ventricular remodeling in patients with acute coronary syndrome
AbstractThe association of the soluble suppression of tumorigenicity 2 (sST2) and the prognosis of heart failure have been well evaluated. However, little is known about the prediction of sST2 for left ventricular (LV) remodeling in acute coronary syndrome (ACS). We investigated the ability of sST2 to predict LV remodeling following the revascularization of ACS. From May 2019 to December 2020, 95 patients with LV ejection fraction (EF)  
Source: Heart and Vessels - August 3, 2021 Category: Cardiology Source Type: research

Progression from normal vessel wall to atherosclerotic plaque: lessons from an optical coherence tomography study with follow-up of over 5  years
This study aimed to observe atherosclerotic progression from normal vessel wall (NVW) to atherosclerotic plaque and examine local factors associated with such progression using  >  5-year long-term follow-up data obtained by serial optical coherence tomography (OCT). A total of 49 patients who underwent serial OCT for lesions with NVW over 5 years (average: 6.9 years) were enrolled. NVW was defined as a vessel wall with an OCT-detectable three-layer structure and intimal thickness ≤ 300 μm. Baseline and follow-up OCT images were matched, and OCT cross sections with NVW&th...
Source: Heart and Vessels - August 2, 2021 Category: Cardiology Source Type: research

Comparison of the catheter ablation outcome in patients between targeting the entrance and exit of the reentry circuit in verapamil-sensitive atrial tachycardia originating from the atrioventricular-node vicinity
AbstractVerapamil-sensitive atrial tachycardia originating from the atrioventricular node vicinity (AVN-AT) can be eliminated with radiofrequency energy (RF) deliveries targeting either the entrance or exit of its reentry circuit. However, the outcome of these different approaches has not been clarified well. Thus, we compared the catheter ablation outcome targeting the entrance of reentry circuit, identified by the entrainment method (Ent-Group; 21 patients) with that targeting the earliest atrial activation site (EAAS) during AT (Exit-Group; 16 patients). There was no significant difference in the tachycardia cycle lengt...
Source: Heart and Vessels - July 6, 2021 Category: Cardiology Source Type: research