Authors ’ reply: clinical implication of thyroid status in patients with atrial fibrillation
(Source: Heart and Vessels)
Source: Heart and Vessels - February 28, 2024 Category: Cardiology Source Type: research
Clinical features, future cardiac events, and prognostic factors following percutaneous coronary intervention in young female patients
ConclusionsRenal dysfunction was strongly associated with future cardiac events in young females who underwent PCI. (Source: Heart and Vessels)
Source: Heart and Vessels - February 27, 2024 Category: Cardiology Source Type: research
Procedural characteristics and cardiovascular outcomes in patients undergoing drug-coated balloon angioplasty for de novo lesions in large coronary arteries: an observational study
AbstractLimited data exist regarding drug-coated balloon (DCB) treatment in de novo large coronary arteries. We sought to demonstrate procedural characteristics, residual stenosis, and clinical outcomes following DCB angioplasty for de novo lesions in large versus small coronary arteries. The study included 184 consecutive patients with 223 de novo coronary lesions undergoing paclitaxel DCB angioplasty between January 2019 and August 2020, who were divided according to whether the DCB diameter was ≥ 3.0 mm (large group,n = 58) or < 3.0 mm (small group,n = 125). The large group had a higher proporti...
Source: Heart and Vessels - February 27, 2024 Category: Cardiology Source Type: research
Hemoglobin is an independent predictor of improvement exercise tolerance in male patients with non-ischemic cardiomyopathy
AbstractExercise intolerance is a symptom of chronic heart failure (CHF). The magnitude of exercise tolerance, as measured by peak oxygen uptake (peak VO2), is strongly associated with prognosis in patients with CHF. We aimed to evaluate the factors associated with improved exercise tolerance in patients with HF. In this prospective study, we recruited patients who were diagnosed with non-ischemic cardiomyopathy between September 2017 and September 2021. All patients underwent cardiopulmonary exercise testing at discharge and 6 months after enrollment. The patients were stratified according to whether peak VO2 was increa...
Source: Heart and Vessels - February 27, 2024 Category: Cardiology Source Type: research
Impact of pemafibrate on lipid profile and insulin resistance in hypertriglyceridemic patients with coronary artery disease and metabolic syndrome
In conclusion, pemafibrate can effectively decrease TG levels in patients with MetS, and it may be a more efficient drug for improving insulin resistance and liver function in such patients. (Source: Heart and Vessels)
Source: Heart and Vessels - February 23, 2024 Category: Cardiology Source Type: research
Thirty-year outcomes of low-intensity anticoagulation for mechanical aortic valve
This study aimed to evaluate the long-term outcomes of low-intensity anticoagulation therapy after aortic valve replacement (AVR) with a mechanical prosthesis. This retrospective cohort study consulted medical records and conducted a questionnaire to investigate 519 patients who underwent single AVR with the St. Jude Medical bileaflet valve and were in sinus rhythm. All patients were followed up with an international normalized ratio (INR) target of 1.6 –2.5, and their INR values were checked throughout the follow-up period. The survival rate, incidence of major adverse cardiac and cerebrovascular events (MACCE), and ris...
Source: Heart and Vessels - February 23, 2024 Category: Cardiology Source Type: research
Prognostic impact of polypharmacy and discharge medications in octogenarians and nonagenarian patients with acute heart failure
AbstractWith the increasing frequency of heart failure (HF) in elderly patients, polypharmacy has become a major concern owing to its adverse outcomes. However, reports on the clinical impact of polypharmacy and discharge medications in hospitalized super-aged patients with acute HF are rare. Data from 682 patients aged 80 years or older, hospitalized for treating acute HF, were analyzed. We recorded the number of medications at discharge and classified them into three groups: HF, non-HF cardiovascular, and non-cardiovascular medications. We investigated the correlation of polypharmacy, defined as daily administrati on o...
Source: Heart and Vessels - February 22, 2024 Category: Cardiology Source Type: research
Clinical implication of thyroid status in patients with atrial fibrillation
(Source: Heart and Vessels)
Source: Heart and Vessels - February 22, 2024 Category: Cardiology Source Type: research
Follistatin-like 1 (FSTL1) levels as potential early biomarker of cardiovascular disease in a Mexican population
AbstractCardiovascular diseases (CVD) are the leading cause of death globally. In recent years, follistatin-like protein 1 (FSTL1) has been proposed as an emerging potential clinical biomarker of CVD, since its concentration is upregulated in heart failure. The aim of the present study was to evaluate the association of FSTL1 levels and classic biomarkers with the risk of CVD in Mexican population. A case –control study was carried out in patients with cardiovascular diseases (CVD), arterial hypertension, but not CVD (cardiovascular risk factor—CRF), and healthy controls (control group) from the Mexican Institute of So...
Source: Heart and Vessels - February 21, 2024 Category: Cardiology Source Type: research
The impact of statins treatments for plaque characteristics in stable angina pectoris patients with very low and high low-density lipoprotein cholesterol levels: an intracoronary optical coherence tomography study
AbstractLow-density lipoprotein cholesterol (LDL-C) levels are recommended according to the patient's risk factors based on guidelines. In patients achieving low LDL-C levels, the need for statins is uncertain, and the plaque characteristics of patients not treated with statins are unclear. In addition, the difference in plaque characteristics with and without statins is unclear in similarly high LDL levels. We evaluate the impact of statins on plaque characteristics on optical coherence tomography (OCT) in patients with very low LDL-C levels and high LDL-C levels. A total of 173 stable angina pectoris patients with 173 le...
Source: Heart and Vessels - February 21, 2024 Category: Cardiology Source Type: research
The effect of off-label use of reduced-dose direct oral anticoagulants therapy in the treatment of pulmonary embolism comparable to standard-dose therapy
In conclusion, while standard-dose DOACs demonstrated superior efficacy in early clot reduction, reduced doses of apixaban and edoxaban showed comparable efficacy and safety profiles in long-term treatment of acute pulmonary embolism in c ertain patients. (Source: Heart and Vessels)
Source: Heart and Vessels - February 21, 2024 Category: Cardiology Source Type: research
Flow pattern analysis of right ventricular outflow tract in repaired tetralogy of Fallot through 4D flow MRI
This study aimed to identify the conditions under which RVOT flow can be acutely evaluated using four-dimensional (4D) flow CMR. Twenty-seven consecutive patients with rTOF underwent both two-dimensional phase-contrast (2D PC) and 4D flow CMR between 2016 and 2018, excluding those with peripheral pulmonary artery stenosis, RVOT conduit replacement, unknown surgical method, and an aortic valve regurgitation greater than 20%. Seven healthy controls also underwent only 4D Flow CMR. All healthy controls and fifteen patients with rTOF showed laminar RVOT flow, while seven patients exhibited helical, and four patients exhibited ...
Source: Heart and Vessels - February 18, 2024 Category: Cardiology Source Type: research
Validation of resting full-cycle ratio and diastolic pressure ratio with [15O]H2O positron emission tomography myocardial perfusion
In conclusion, the novel non-hyperemic pressure ratios, RFR and dPR, have a diagnostic performance comparable to FFR in assessing regional myocardial ischemia. These findin gs suggest that RFR and dPR may be considered as an FFR alternative for invasively guiding revascularization treatment in symptomatic patients with CAD. (Source: Heart and Vessels)
Source: Heart and Vessels - February 17, 2024 Category: Cardiology Source Type: research
Difference in one-year late lumen loss between high- and low-dose paclitaxel-coated balloons for femoropopliteal disease
The objective of the study is to investigate the difference in 1-year late lumen loss (LLL) between the high- (IN.PACT Admiral) and low-dose (Lutonix) paclitaxel-coated balloon (PCB). Although a recent randomized clinical trial demonstrated no difference in efficacy endpoint between high- and low-dose PCB, it remains unclear whether high-dose PCB was superior to low-dose PCB in actual clinical practice. We enrolled 64 patients with 67 de novo femoropopliteal lesions who underwent PCB angioplasty at Kokura Memorial Hospital from May 2014 to March 2020 and subsequent follow-up angiography after 1 year. The primary endpoint...
Source: Heart and Vessels - February 16, 2024 Category: Cardiology Source Type: research
Predicting residual pressure gradients after balloon angioplasty in patients with femoropopliteal artery lesions
AbstractIn endovascular therapy (EVT) for femoropopliteal artery (FPA) lesions, studies examining the relationship between lesion morphology and hemodynamic status are limited. The purpose of this study was to investigate FPA lesion characteristics, including imaging findings and their cutoff values that can predict hemodynamic significance after balloon angioplasty. This single-center retrospective study enrolled 50 de novo FPA lesions from 43 patients treated under intravascular ultrasound (IVUS) usage between June 2022 and March 2023. As a physiological parameter, the pressure gradient was measured, and the cutoff value...
Source: Heart and Vessels - February 12, 2024 Category: Cardiology Source Type: research
