Clinical characteristics of tetralogy of Fallot with left pulmonary artery acute angulation on computed tomography
AbstractLeft pulmonary artery (LPA) stenosis with acute angulation commonly necessitates surgical revision in the treatment of tetralogy of Fallot (TOF). We investigated the clinical characteristics of acute angulation of the LPA in patients with TOF via computed tomography (CT). Between 2011 and 2022, 160 patients were diagnosed with TOF using CT. After excluding 28 patients due to insufficient records or age, 132 patients were included in the present analysis. The patients were divided into two groups according to the presence or absence of acute angulation of the LPA: group I (TOF with an acute angle of the LPA, n  =...
Source: Heart and Vessels - September 26, 2023 Category: Cardiology Source Type: research

The efficacy and safety of sacubitril/valsartan in heart failure with reduced ejection fraction patients with hypotension
This study aimed to investigate the efficacy and safety of sacubitril/valsartan (S/V) in HFrEF patients with hypotension. We included 43 consecutive HFrEF patients with sBP  <  100 mmHg despite guideline-directed medical therapy for at least 3 months and who received S/V between September 2020 and July 2021. Patients admitted for acute heart failure were excluded and 29 patients were evaluated for safety endpoints. Furthermore, patients who performed non-pharmacologic al therapy or died within 1 month were excluded, finally, 25 patients were evaluated for efficacy endpoints. The mean initial S/V dose was 53.0 ...
Source: Heart and Vessels - September 26, 2023 Category: Cardiology Source Type: research

Dipeptidyl peptidase-4 inhibitors reduce the incidence of first cardiovascular events in Japanese diabetic patients
ConclusionsOur findings have demonstrated that the use of DPP-4 inhibitors may be associated with a reduced incidence of first cardiovascular events in Japanese diabetic patients. The results require confirmation in randomized controlled trials. (Source: Heart and Vessels)
Source: Heart and Vessels - September 26, 2023 Category: Cardiology Source Type: research

Relationship of maximum walking speed with peak oxygen uptake and anaerobic threshold in male patients with heart failure
AbstractThis retrospective observational study aimed to examine the relationships of maximum walking speed (MWS) with peak oxygen uptake (peak VO2) and anaerobic threshold (AT) obtained by cardiopulmonary exercise testing (CPX) in patients with heart failure. The study participants were 104 consecutive men aged  ≥ 20 years who had been hospitalized or had undergone outpatient care at our hospital for heart failure between February 2019 and January 2023. MWS was measured in a 5-m section with a 1-m run-up before and after the course. Multivariable analysis was used to examine the association between MWS and peak VO2 ...
Source: Heart and Vessels - September 26, 2023 Category: Cardiology Source Type: research

Impact of “black rock” on clinical outcomes after endovascular therapy for de novo calcified femoropopliteal lesions
AbstractThe relationship between severity of calcification and clinical outcomes after endovascular therapy (EVT) for femoropopliteal lesions is well known. We often encounter dense calcifications in our daily practice, which are darker than normal calcifications on angiography. Accordingly, we named it “black rock” (BR), and investigated its impact on clinical outcomes after EVT. We retrospectively analyzed 677 lesions in 495 patients who underwent EVT for de novo calcified femoropopliteal lesions at our hospital between April 2007 and June 2020. BR is defined as a calcification which is 1 cm or more in length, occup...
Source: Heart and Vessels - September 25, 2023 Category: Cardiology Source Type: research

The efficacy and safety of sacubitril/valsartan in heart failure with reduced ejection fraction patients with hypotension
This study aimed to investigate the efficacy and safety of sacubitril/valsartan (S/V) in HFrEF patients with hypotension. We included 43 consecutive HFrEF patients with sBP  <  100 mmHg despite guideline-directed medical therapy for at least 3 months and who received S/V between September 2020 and July 2021. Patients admitted for acute heart failure were excluded and 29 patients were evaluated for safety endpoints. Furthermore, patients who performed non-pharmacologic al therapy or died within 1 month were excluded, finally, 25 patients were evaluated for efficacy endpoints. The mean initial S/V dose was 53.0 ...
Source: Heart and Vessels - September 25, 2023 Category: Cardiology Source Type: research

Dipeptidyl peptidase-4 inhibitors reduce the incidence of first cardiovascular events in Japanese diabetic patients
ConclusionsOur findings have demonstrated that the use of DPP-4 inhibitors may be associated with a reduced incidence of first cardiovascular events in Japanese diabetic patients. The results require confirmation in randomized controlled trials. (Source: Heart and Vessels)
Source: Heart and Vessels - September 25, 2023 Category: Cardiology Source Type: research

Relationship of maximum walking speed with peak oxygen uptake and anaerobic threshold in male patients with heart failure
AbstractThis retrospective observational study aimed to examine the relationships of maximum walking speed (MWS) with peak oxygen uptake (peak VO2) and anaerobic threshold (AT) obtained by cardiopulmonary exercise testing (CPX) in patients with heart failure. The study participants were 104 consecutive men aged  ≥ 20 years who had been hospitalized or had undergone outpatient care at our hospital for heart failure between February 2019 and January 2023. MWS was measured in a 5-m section with a 1-m run-up before and after the course. Multivariable analysis was used to examine the association between MWS and peak VO2 ...
Source: Heart and Vessels - September 25, 2023 Category: Cardiology Source Type: research

The efficacy and safety of adaptive servo-ventilation therapy for heart failure with preserved ejection fraction
AbstractIt is unclear whether adaptive servo-ventilation (ASV) therapy for heart failure with preserved ejection fraction (HFpEF) is effective. The aim of this study was to investigate the details of ASV use, and to evaluate the effectiveness and safety of ASV in real-world HFpEF patients. We retrospectively enrolled 36 HFpEF patients at nine cardiovascular centers who initiated ASV therapy during hospitalization or on outpatient basis and were able to continue using it at home from 2012 to 2017 and survived for at least one year thereafter. The number of hospitalizations for heart failure (HF) during the 12  months befor...
Source: Heart and Vessels - September 24, 2023 Category: Cardiology Source Type: research

Postoperative evaluation of left atrial stiffness in patients with congenital heart diseases
This study aimed to evaluate LA stiffness in CHD patients postoperatively. Seventy-five patients (CHDs, 67; controls, 8; age range, 10 –41 years) who underwent cardiac catheterization at our institution were included in this study. From the pulmonary artery wedge pressure waveform obtained during cardiac catheterization, the pressure range between the v wave and x trough was determined, and this value was divided by the LA reser voir strain obtained by echocardiography to calculate LA stiffness, as previously reported. LA stiffness was significantly higher in postoperative CHD patients than in controls (0.28 ± 0.17...
Source: Heart and Vessels - September 22, 2023 Category: Cardiology Source Type: research

Left ventricular reverse remodeling following initiation of sacubitril/valsartan for heart failure with reduced ejection fraction and low blood pressure
In conclusion, significant LV reverse remodeling occurred after initiation of sacubitril/valsartan, even in HF patients with LVEF <  50% and systolic blood pressure ≤ 100 mmHg. (Source: Heart and Vessels)
Source: Heart and Vessels - September 21, 2023 Category: Cardiology Source Type: research

Effect of in-patient cardiac rehabilitation at rehabilitation hospital for cardiology patients: two-center trial
In conclusion, in rehabilitation hospitals, patients with cardiovascular disease were older, had lower preadmission ADL, and had lower a physical function at transfer than those who underwent cardiovascular surgery, but CR improved physical function and QOL to the same extent. The results suggest that the recovery of patients with cardiovascular disease may be similar to those who undergo cardiovascular surgery. (Source: Heart and Vessels)
Source: Heart and Vessels - September 13, 2023 Category: Cardiology Source Type: research