Age- and sex-stratified normal values for circulatory and ventilatory power during ramp exercise derived from a healthy Japanese population
AbstractCirculatory power (CP) and ventilatory power (VP), obtained by cardiopulmonary exercise testing (CPX), have been suggested to be excellent prognostic markers for heart failure. However, the normal values of these parameters in healthy Japanese populations remain unknown; thus, we aimed to investigate these values in such a population. A total of 391 healthy Japanese participants, 20 –78 years of age, underwent CPX with a cycle ergometer with ramp protocols. Systolic blood pressure (SBP), heart rate, oxygen uptake (\(\dot{{\text{V}}}\)O2) at peak exercise, and the slope of minute ventilation (\(\dot{{\text{V}}}\)...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Diuretic and renal effects of angiotensin receptor-neprilysin inhibitor in patients hospitalized for acute heart failure
AbstractIn patients hospitalized for acute decompensation of heart failure (HF), the impact of angiotensin receptor-neprilysin inhibitor (ARNI) on diuresis and renal function has not been fully investigated. Patients with HF and reduced ejection fraction who were hospitalized for acute decompensation and newly initiated ARNI after hemodynamic stabilization were enrolled. Changes in urine volume (UV), body weight, estimated glomerular filtration rate (eGFR), and urine N-acetyl-beta-d-glucosaminidase (uNAG) levels before and after ARNI initiation were investigated. Changes in the diuretic response [DR, calculated as urine vo...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Relationship between health literacy and physical function of patients participating in phase I cardiac rehabilitation: a multicenter clinical study
This study showed that HL was significantly associated with handgrip strength an d SPPB in cardiac rehabilitation patients and suggests the possibility of early screening for low HL to improve physical function in cardiac rehabilitation patients with low HL.Graphical Abstract (Source: Heart and Vessels)
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Left-atrial volume reduction reflects improvement of cardiac sympathetic nervous function in patients with severe aortic stenosis after transcatheter aortic valve replacement
In conclusion, LA volume reduction reflected CSN functional improvement after TAVR. In patients with TAVR, ∆LAVI% might be a valuable parameter for evaluating CSN functional recovery. (Source: Heart and Vessels)
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

H2ARDD score as a feasible predictor of heart failure events in patients with atrial fibrillation: a validation study
In conclusion, the H2ARDD score may be feasible for HF risk stratification in patients with AF. (Source: Heart and Vessels)
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Predictors of physical frailty improvement in older patients enrolled in a multidisciplinary cardiac rehabilitation program
AbstractCardiac rehabilitation (CR) improves clinical and functional recovery in older patients after acute cardiac syndromes, whose outcome is influenced by cardiac disease severity, but also by comorbidity and frailty. The aim of the study was to analyze the predictors of physical frailty improvement during the CR program. Data were collected in all patients aged  >  75 years consecutively admitted from 1 January to December 2017 to our CR, consisting of 5-day-per-week of 30-min session of biking or calisthenics on alternate days for 4 weeks. Physical frailty was measured with short physical performance battery ...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Clinical outcomes after coronary artery bypass grafting in patients with dialysis-dependent end-stage renal disease and an analysis of the related influencing factors
AbstractPerioperative and short/mid-term survival rates of dialysis-dependent patients with end-stage renal disease (ESRD), who undergo coronary artery bypass grafting (CABG), and the factors influencing mortality are not well evaluated In China. We retrospectively analyzed the perioperative and postoperative 1-, 3-, and 5-year survival rates of 53 dialysis-dependent ESRD patients who underwent CABG, and compared the factors related to perioperative mortality and all-cause mortality during the postoperative follow-up. Survival rates were expressed as Kaplan –Meier survival curves, and factors influencing the follow-up su...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

The association between C-peptide and atrial cardiomyopathy in nondiabetic adults: results from NHANES III
AbstractSerum C-peptide exhibits various biological activities. The relationship between C-peptide and atrial cardiomyopathy remains unknown. We aimed to investigate the association between C-peptide level and atrial cardiomyopathy in nondiabetic adults. Our study enrolled 4578 participants without diagnosed diabetes from the Third National Health and Nutrition Examination Survey (NHANES III). Atrial cardiomyopathy was defined as a deep terminal negative P wave in V1 below − 100 µV (more negative), according to the electrocardiogram. The participants were categorized into low C-peptide (≤ 1.46 nmol/L) and high C-...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Cardiovascular events in patients with deferred lesions and chronic kidney disease
AbstractNo study has reported the association between the worsening of chronic kidney disease (CKD) and cardiovascular events in patients with deferred coronary artery lesions. We included patients with deferred lesions, defined as a fractional flow reserve (FFR) value  >  0.80 treated with conservative medical therapy. Patients were divided into three groups: group 1, CKD stages 1–2; group 2, CKD stages 3–5; and group 3, CKD stage 5D (hemodialysis), with the clinical outcomes compared. The primary endpoint was the first occurrence of target vessel myocardial i nfarction, ischemia-driven target-vessel revascular...
Source: Heart and Vessels - July 10, 2023 Category: Cardiology Source Type: research

The estimation of coronary artery calcium thickness by computed tomography angiography based on optical coherence tomography measurements
In conclusion, this novel method provided the estimation of calcium thickness more accurately than conventional methods. (Source: Heart and Vessels)
Source: Heart and Vessels - July 9, 2023 Category: Cardiology Source Type: research

Left atrial conduction times and regional velocities in persistent atrial fibrillation patients with and without fibrotic atrial cardiomyopathy
This study evaluates left atrial conduction times and conduction velocities based on high-density voltage and activation maps in sinus rhythm (CARTO®3 V7) of 53 patients with persistent atrial fibrillation (LVEF 60% (55 –60 IQR), LAVI 39 ml/m2 (31 –47 IQR), LApa 24 ± 6 cm2). Measurements were made in low voltage areas (LVA  ≤ 0.5 mV) and normal voltage areas (NVA ≥ 1.5 mV) at the left atrial anterior and posterior walls. Maps of 28 FACM and 25 no FACM patients were analyzed (19 FACM I/II, 9 FACM III/IV, LVA 14 ± 11 cm2). Left atrial conduction time averaged to 110  ± 24 ms but was shown ...
Source: Heart and Vessels - July 7, 2023 Category: Cardiology Source Type: research

Influence of cardiac biomarkers on predicting significant coronary artery disease in hypertrophic cardiomyopathy patients
ConclusionTo sum up, we suggest that cardiac biomarkers were valuable and simple parameters in terms of significant CAD in HCM patients. (Source: Heart and Vessels)
Source: Heart and Vessels - July 7, 2023 Category: Cardiology Source Type: research

Left atrial conduction times and regional velocities in persistent atrial fibrillation patients with and without fibrotic atrial cardiomyopathy
This study evaluates left atrial conduction times and conduction velocities based on high-density voltage and activation maps in sinus rhythm (CARTO®3 V7) of 53 patients with persistent atrial fibrillation (LVEF 60% (55 –60 IQR), LAVI 39 ml/m2 (31 –47 IQR), LApa 24 ± 6 cm2). Measurements were made in low voltage areas (LVA  ≤ 0.5 mV) and normal voltage areas (NVA ≥ 1.5 mV) at the left atrial anterior and posterior walls. Maps of 28 FACM and 25 no FACM patients were analyzed (19 FACM I/II, 9 FACM III/IV, LVA 14 ± 11 cm2). Left atrial conduction time averaged to 110  ± 24 ms but was shown ...
Source: Heart and Vessels - July 7, 2023 Category: Cardiology Source Type: research