National survey of percutaneous coronary intervention during the COVID-19 pandemic in Japan: second report of the Japanese Association of Cardiovascular Intervention and Therapeutics
This study aimed to describe changes in PCI practices during the health emergency at the national level. The Japanese Association of Cardiovascular Intervention and Therapeutics performed provided serial surveys of institutions throughout Japan during the pandemic. The data obtained on December, 2020 and February 2021 (during the 2nd wave of pandemic) were compared with the data obtained on August 2020 (1st wave). Primary PCI for STEMI was performed as usual in 99.1%, 98.7%, and 97.5% of institutions in mid-August, mid-December, 2020 and mid-February, 2021, respectively. The COVID-19 screening tests rates in patients were ...
Source: Cardiovascular Intervention and Therapeutics - April 17, 2021 Category: Cardiology Source Type: research

Clinical implications of the invagination of an interwoven nitinol stent: a single-center retrospective analysis
AbstractStent invagination (SIV) sometimes occurs during interwoven nitinol stent (IWS) placement due to its complex deployment system. It may cause stent malapposition and reduce the minimum stent area. However, the clinical implications of SIV remain unclear. This retrospective single-center study sought to assess the clinical implications of IWS invagination in the femoropopliteal lesions in patients with peripheral arterial diseases. Thirty-two consecutive patients (23 men, mean age of 74  years, 34 limbs) with symptomatic femoropopliteal lesions who had received IWS implantation from January to July 2019 were enr...
Source: Cardiovascular Intervention and Therapeutics - April 15, 2021 Category: Cardiology Source Type: research

Prasugrel switching from clopidogrel after percutaneous coronary intervention for acute coronary syndrome in Taiwanese patients: an analysis of safety and efficacy
AbstractThe recommended maintenance dose of prasugrel for East Asian populations (i.e., Japanese and Taiwanese) is 3.75  mg as part of dual antiplatelet therapy (DAPT) for the prevention of recurrent ischemia and stent thrombosis in acute coronary syndrome (ACS). This modified dosage regimen has been established in studies conducted in Japan; however, the efficacy and safety of switching from clopidogrel to prasugre l DAPT among Taiwanese patients remain to be explored. In this phase IV, multicenter, single-arm, open-label study, we evaluated the 4-week pharmacodynamic response, and the 48-week safety outcomes of pras...
Source: Cardiovascular Intervention and Therapeutics - April 4, 2021 Category: Cardiology Source Type: research

Left ventricular apical pseudoaneurysm with shunt to the right ventricle following transapical aortic valve replacement
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - April 2, 2021 Category: Cardiology Source Type: research

Acute aortic regurgitation underestimated by transesophageal echocardiography after preparatory balloon aortic valvuloplasty during transcatheter aortic valve implantation for severe aortic stenosis
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - April 1, 2021 Category: Cardiology Source Type: research

Crossroads: advanced guidance through an aortic coarctation by fusion imaging in transfemoral TAVR after aorto-aortic bypass
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - March 29, 2021 Category: Cardiology Source Type: research

The Japanese Association of Cardiovascular Intervention and Therapeutics position statement on coronary invasive procedures during the COVID-19 pandemic in Japan
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - March 22, 2021 Category: Cardiology Source Type: research

Consensus document on the standard of coronary angioscopy examination and assessment from the Japanese Association of Cardiovascular Intervention and Therapeutics
AbstractCoronary angioscopy (CAS) is a unique diagnostic device that allows direct visualization of the vascular luminal surface in living patients. CAS contributes to elucidate the pathology of coronary artery disease. This consensus document provides a standard for CAS examination and assessment. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - March 20, 2021 Category: Cardiology Source Type: research

Possible risk factors for tip rupture of orbital atherectomy system
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - March 5, 2021 Category: Cardiology Source Type: research

A contemporary review of clinical significances of percutaneous coronary intervention for chronic total occlusions, with some Japanese insights
AbstractThe clinical “significance” of percutaneous coronary intervention for coronary chronic total occlusion (CTO-PCI) has been evaluated. In the beginning, the effects on clinical endpoints were investigated by comparisons between cases of success and failure of CTO-PCI, which mostly demonstrated better long-term outcomes in the successful cases. Similarly, improvement of cardiac function or wall motion was proven by serial observational studies. Accordingly, several prospective randomized trials (RCTs), which should confirm such accumulated potential benefits, were recently conducted by comparison with stu ...
Source: Cardiovascular Intervention and Therapeutics - March 3, 2021 Category: Cardiology Source Type: research

Comparison of quantitative measurements between two different intravascular ultrasound catheters and consoles: in vitro and in vivo studies
In conclusion, two IVUS catheters and consoles provide comparable IVUS measures both in vitro and in vivo. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 27, 2021 Category: Cardiology Source Type: research

Influence of dual antiplatelet therapy duration on neointimal condition after second-generation drug-eluting stent implantation
In conclusion, interrupting DAPT 9 months after second-generation DES implantation did not affect the development of in-stent thrombus, neointimal proliferation or stent strut coverage at 18-month follow-up compared with continuing DAPT. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 26, 2021 Category: Cardiology Source Type: research

Angiographic evaluation of radial artery injury after transradial approach for percutaneous coronary intervention
AbstractThe transradial approach for percutaneous coronary intervention (TRA-PCI) has been increasingly gaining popularity in clinical practice. However, its association with risk for long-term radial artery injury has not been yet thoroughly defined. We retrospectively examined the patients undergoing radial artery angiography (RAG) after TRA-PCI to determine the incidence and risk factors of radial artery injury. The study included 558 patients undergoing follow-up radial artery angiography at 12  month after TRA-PCI. Radial artery injury occurred in 140 patients (25%) with 3 distinct morphological patterns: focal r...
Source: Cardiovascular Intervention and Therapeutics - February 26, 2021 Category: Cardiology Source Type: research

Usefulness of tip detection method for side branches where guidewires are difficult to pass in coronary intervention
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 16, 2021 Category: Cardiology Source Type: research

Correction to: Influence of CYP2C19 genotypes for the effect of 1 ‑month dual antiplatelet therapy followed by clopidogrel monotherapy relative to 12‑month dual antiplatelet therapy on clinical outcomes after percutaneous coronary intervention: a genetic substudy from the STOPDAPT‑2
In the original publication of the article, Fig.  4(B) and 4(C) were published incorrectly. The correct figures are given in this correction. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 12, 2021 Category: Cardiology Source Type: research

Effective treatment of iatrogenic femoral pseudoaneurysms by combined endovascular balloon inflation and percutaneous thrombin injection
In conclusion, the combination of percutaneous thrombin injection and endovascular balloon inflation was feasible and safe for the treatment of IFAPs. This technique may contribute to the treatment of IFAPs. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 12, 2021 Category: Cardiology Source Type: research

Delayed re-bleeding after balloon-expandable stent-graft implantation for an iliac artery rupture during transcatheter aortic valve implantation
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 10, 2021 Category: Cardiology Source Type: research

Japanese multicenter registry evaluating the antegrade dissection reentry with cardiac computerized tomography for chronic coronary total occlusion
AbstractRecently, antegrade dissection re-entry (ADR) with re-entry device for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has evolved to become one of the pillar techniques of the hybrid algorithm. Although the success rate of the device is high, it could be improved. We sought to evaluate the current trends and issues associated with ADR in Japan and evaluate the potential of cardiac computed tomography angiography (CCTA) for ADR procedure. A total 48 patients with CTO suitable for ADR evaluated by baseline conventional angiography and CCTA were enrolled. Procedural success and technical succes...
Source: Cardiovascular Intervention and Therapeutics - February 7, 2021 Category: Cardiology Source Type: research

Comparative performance analysis of interventional devices for the treatment of ischemic disease in below-the-knee lesions: a systematic review and meta-analysis
AbstractThis meta-analysis aimed to evaluate the device performance of conventional balloon catheters (POBA), drug-coated balloons (DCB), bare-metal stents (BMS), and drug-eluting stents (DES) in below-the-knee (BTK) ischemic lesions with regard to lesion characteristics. Online searches of PubMed, Web of Science, and Cochrane databases (2010 –2019) were conducted for each of the test devices. Primary patency rates (pp) and major amputation rates 1 year after the use of each device were analyzed using a random-effects meta-analysis model. Meta-regression analysis was conducted to test associations between the ou...
Source: Cardiovascular Intervention and Therapeutics - February 6, 2021 Category: Cardiology Source Type: research

In-stent protruding bump with abnormal IVUS images causing acute coronary syndrome in a hemodialysis patient
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - February 1, 2021 Category: Cardiology Source Type: research

Acquired coronary aneurysm after stent implantation at a bifurcation excluded with a Papyrus covered stent subsequently fenestrated
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 29, 2021 Category: Cardiology Source Type: research

Direct puncture technique efficacy for the treatment of cystic adventitial degeneration of the popliteal artery
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 29, 2021 Category: Cardiology Source Type: research

Ventricular septal rupture with ventricular septal dissection and coronary artery fistula after acute myocardial infarction
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 26, 2021 Category: Cardiology Source Type: research

Directional coronary atherectomy via Amplatz left guiding catheter
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 25, 2021 Category: Cardiology Source Type: research

Peri-stent contrast staining after ultrathin, biodegradable polymer sirolimus-eluting stent implantation: findings from optical coherence tomography and coronary angioscopy
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 23, 2021 Category: Cardiology Source Type: research

Mortality risk after use of a paclitaxel-coated stent in femoropopliteal peripheral artery disease
AbstractAlthough paclitaxel-based devices which demonstrated improved outcomes in the treatment of lower-extremity peripheral artery disease (PAD) have been used worldwide, Katsanos et al. reported a systematic review and summary-level meta-analysis of RCTs in which application of paclitaxel-based devices in the femoropopliteal artery was associated with an increased mortality risk. The purpose of this study was to describe the safety of endovascular therapy (EVT) using paclitaxel-coated stents for femoropopliteal disease by evaluating the mortality risk compared with patients treated with paclitaxel-free devices. A retros...
Source: Cardiovascular Intervention and Therapeutics - January 22, 2021 Category: Cardiology Source Type: research

Impact of stent platform on strut deformation after kissing balloon inflation in bifurcation lesion
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 22, 2021 Category: Cardiology Source Type: research

Optical coherence tomography-guided percutaneous coronary intervention: a review of current clinical applications
AbstractOptical coherence tomography (OCT) is an emerging high-resolution intravascular imaging modality that can provide physicians with critical information, thereby enabling precise characterization of plaque morphology and luminal geometry and facilitating pre-intervention lesion assessment. As OCT has a higher sensitivity for lipid-rich plaque characterization than intravascular ultrasound, vulnerable plaque detection by OCT has thus been investigated. By evaluating both the calcium thickness and arc, OCT can be the ideal method for determining both the indication and endpoint of rotational atherectomy for calcified l...
Source: Cardiovascular Intervention and Therapeutics - January 17, 2021 Category: Cardiology Source Type: research

Difference in basic concept of coronary bifurcation intervention between Korea and Japan. Insight from questionnaire in experts of Korean and Japanese bifurcation clubs
AbstractThe coronary bifurcation intervention varies among countries due to the differences in assessment of lesion severity and treatment devices. We sought to clarify the difference in basic strategy between South Korea and Japan. A total of 19 and 32 experts from Korean (KBC) and Japanese Bifurcation Clubs (JBC), respectively, answered a survey questionnaire concerning their usual procedure of coronary bifurcation intervention. JBC experts performed less two-stent deployment in the left main (LM) bifurcation compared to KBC experts (JBC vs. KBC: median, 1 –10% vs. 21–30%,p 
Source: Cardiovascular Intervention and Therapeutics - January 16, 2021 Category: Cardiology Source Type: research

A systematic review and meta-analysis of delayed coronary artery access for coronary angiography with or without percutaneous coronary intervention (PCI) in patients who underwent transcatheter aortic valve replacement (TAVR)
AbstractCoronary artery disease (CAD) and severe aortic valve stenosis frequently coexist. Given the progressive nature of CAD, silent or non-significant CAD may become symptomatic or functionally relevant years after TAVR. However, there is a paucity of data documenting the feasibility of either coronary angiography and/or PCI after TAVR. We systematically searched Medline, Pubmed, Embase, Cochrane database, Google Scholar, Science Direct, Web of Science, and conference abstracts from conception to March 2020 using OvidSP in TAVR patients undergoing coronary angiography with or without PCI at least 6  months after TA...
Source: Cardiovascular Intervention and Therapeutics - January 16, 2021 Category: Cardiology Source Type: research

Drug-eluting stent thrombosis: current and future perspectives
AbstractOver the past 40  years, the safety and efficacy of percutaneous coronary intervention has dramatically improved by overcoming several challenges. The introduction of drug-eluting stent (DES) in particular was a major breakthrough in interventional cardiology. Compared to bare-metal stents, first-generation DES (G1 -DES) has dramatically reduced the rates of in-stent restenosis and subsequent target lesion revascularization. However, major safety concerns surrounding stent thrombosis (ST) emerged with G1-DES in clinical practice as a result of the high incidences of death, myocardial infarction, and repeat rev...
Source: Cardiovascular Intervention and Therapeutics - January 13, 2021 Category: Cardiology Source Type: research

Practical utilization of cardiac computed tomography for the success in complex coronary intervention
AbstractPercutaneous coronary intervention (PCI) for complex lesions is still technically demanding and is associated with less favorable procedural parameters such as lower success rate, longer procedural time, higher contrast volume and unexpected complications. Because the conventional angiographic analysis is limited by the inability to visualize the plaque information and the occluded segment, cardiac computed tomography has evolved as an adjunct to invasive angiography to better characterize coronary lesions to improve success rates of PCI. Adding to routine image reconstructions by coronary computed tomography angio...
Source: Cardiovascular Intervention and Therapeutics - January 11, 2021 Category: Cardiology Source Type: research

Clinical outcomes in nonagenarians undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis
AbstractTo compare the risk of procedural complications and mortality after transcatheter aortic valve implantation (TAVI) in nonagenarians (age  ≥ 90 years) compared to younger patients (
Source: Cardiovascular Intervention and Therapeutics - January 11, 2021 Category: Cardiology Source Type: research

Temporal trends in coronary intervention strategies and the impact on one-year clinical events: data from a Japanese multi-center real-world cohort study
AbstractPercutaneous coronary intervention (PCI) has significantly advanced over the last 40  years, but it is not clear whether there have been any changes in prognosis in recent years. The Kumamoto Intervention Conference Study Real-World Registry is a multi-center registry that enrolls consecutive patients undergoing PCI in 17 centers in Kyushu, Japan. To elucidate the clinical impact o f recent changes in treatment strategies, 8841 consecutive participants (historical PCI:n = 4038, enrolled between January 2013 and December 2014, and current PCI:n = 4803, between January 2015 and March ...
Source: Cardiovascular Intervention and Therapeutics - January 9, 2021 Category: Cardiology Source Type: research

Correction to: Role of acetylcholine spasm provocation test as a pathophysiological assessment in nonobstructive coronary artery disease
Correct Fig.  3 and (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 5, 2021 Category: Cardiology Source Type: research

Efficacy of the Wolverine cutting balloon on a circumferential calcified coronary lesion: Bench test using a three-dimensional printer and computer simulation with the finite element method
This study aimed to explore the optimal method of dilation of highly calcified lesions using a cutting balloon. Calcification models were developed from patient computed tomography and intravascular ultrasound data, and were constructed using three-dimensional printers. The lesions were dilated using a Wolverine ™ cutting balloon and NC Emerge™ noncompliant balloon catheter, and the success rate of dilation and maximum dilation pressure were compared. The maximum first principal stresses in calcified lesions were also evaluated by computer simulation using the finite element method. In the bench test, t he dila...
Source: Cardiovascular Intervention and Therapeutics - January 3, 2021 Category: Cardiology Source Type: research

Correction to: Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics
The article Clinical expert consensus document on rotational atherectomy (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 3, 2021 Category: Cardiology Source Type: research

Successful exclusion of coronary artery aneurysm by utilizing shortening of covered stent to avoid side-branch occlusion
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - January 2, 2021 Category: Cardiology Source Type: research

Factors associated with long-term major adverse cardiac events of coronary bioresorbable vascular scaffold
AbstractThe long-term clinical outcomes after implantation of bioresorbable vascular scaffolds (BVS) in a real-world cohort were not well described. To identify factors associated with major adverse cardiovascular events (MACE) on long-term follow-up after implantation of BVS in patients undergoing elective percutaneous coronary intervention (PCI). This was an observational study based on a hospital registry of percutaneous coronary intervention. Participants were consecutive patients who underwent PCI and implanted with at least one everolimus-eluting BVS (Absorb®) in a single center between 2014 and 2017. Among the 1...
Source: Cardiovascular Intervention and Therapeutics - January 2, 2021 Category: Cardiology Source Type: research

Early hemodynamic changes after transcatheter aortic valve implantation in patients with severe aortic stenosis measured by invasive pressure volume loop analysis
AbstractReplacement of a stenotic aortic valve reduces immediately the ventricular to aortic gradient and is expected to improve diastolic and systolic left ventricular function over the long term. However, the hemodynamic changes immediately after valve implantation are so far poorly understood. Within this pilot study, we performed an invasive pressure volume loop analysis to describe the early hemodynamic changes after transcatheter aortic valve implantation (TAVI) with self-expandable prostheses. Invasive left ventricular pressure volume loop analysis was performed in 8 patients with aortic stenosis (mean 81.3  ye...
Source: Cardiovascular Intervention and Therapeutics - December 12, 2020 Category: Cardiology Source Type: research

Transfemoral transcatheter aortic valve implantation for bicuspid aortic stenosis with tortuous aorta after total arch replacement
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - December 7, 2020 Category: Cardiology Source Type: research

Displaced urinary bladder: a sign of iliac rupture
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 27, 2020 Category: Cardiology Source Type: research

Mechanisms of drug-eluting stent restenosis
AbstractDrug-eluting stents (DES) were developed to overcome in-stent restenosis (ISR), which has long been considered the main complication limiting the long-term efficacy of coronary stenting. New-generation DES which composed of advanced stent design with and without specific biocompatible polymer contributes a reduction of the incidence of ISR to rate ranging from 5 to 10%. The precise reasons of DES restenosis are still controversial and not fully understood. Angiographic and coronary images at the index procedure, systemic status of patients, medications, and intracoronary imaging at ISR site are all considered to fi...
Source: Cardiovascular Intervention and Therapeutics - November 21, 2020 Category: Cardiology Source Type: research

Distal radial approach: a review on achieving a high success rate
ConclusionThe dRA is a new approach site for PCI. Further research is warranted for the selection of suitable patients to undergo PCI through the dRA. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 21, 2020 Category: Cardiology Source Type: research

Clinical outcomes of transcatheter aortic valve implantation in failed bioprosthetic surgical valves vs. native aortic stenosis: insights from a meta-analysis
AbstractThere is no meta-analysis comparing clinical outcomes between valve-in-valve transcatheter aortic valve implantation for failed surgical bioprosthetic valves (ViV-TAVI) and native valve TAVI for aortic stenosis (NV-TAVI). We aimed to investigate clinical outcomes between ViV-TAVI and NV-TAVI using a meta-analysis. EMBASE and MEDLINE were searched through April 2020 to investigate the comparative outcomes between ViV-TAVI and NV-TAVI. The main outcomes were short-term (30-day/in-hospital) mortality, pacemaker implantation (PMI), life threatening and/or major bleeding, stroke, and coronary obstruction, and long-term ...
Source: Cardiovascular Intervention and Therapeutics - November 18, 2020 Category: Cardiology Source Type: research

Simultaneous procedure of MitraClip and WATCHMAN implantation in a patient with atrial fibrillation and severe mitral regurgitation: the first case in Japan
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 18, 2020 Category: Cardiology Source Type: research

Tip detection method adapted for identification of plaque localization during directional coronary atherectomy procedure
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 13, 2020 Category: Cardiology Source Type: research

Influence of CYP2C19 genotypes for the effect of 1-month dual antiplatelet therapy followed by clopidogrel monotherapy relative to 12-month dual antiplatelet therapy on clinical outcomes after percutaneous coronary intervention: a genetic substudy from the STOPDAPT-2
In conclusion, for the selected patients in STOPDAPT-2 trial, CYP2C19 LOF alleles had no significant, consistent interaction with the effect of 1-month DAPT relative to 12-month DAPT for clinical outcomes, although the study was overtly underpowered.Trial registrySTOPDAPT-2 ClinicalTrials.gov number, NCT02619760. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 12, 2020 Category: Cardiology Source Type: research

Contemporary coronary drug-eluting and coated stents: a mini-review
AbstractPercutaneous coronary intervention has become a standard-of-care procedure in patients with acute and chronic coronary syndromes, in which coronary stent technology is commonly used. In this mini-review article, we summarize the characteristics of contemporary coronary drug-eluting and coated stents. (Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 10, 2020 Category: Cardiology Source Type: research

Bailout technique for the guide extension catheter entrapment by a coronary stent
(Source: Cardiovascular Intervention and Therapeutics)
Source: Cardiovascular Intervention and Therapeutics - November 10, 2020 Category: Cardiology Source Type: research