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Condition: Intermittent Claudication

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Total 179 results found since Jan 2013.

11-dehydro thromboxane B2 levels after percutaneous transluminal angioplasty in patients with peripheral arterial occlusive disease during a one year follow-up period.
In this study, 175 patients diagnosed with peripheral arterial occlusive disease (PAOD) and demonstrating short-distance claudication or ischemic rest pain, requiring PTA in either the iliac, femoral, or popliteal arteries, were enrolled. The excretion of 11-dehydro thromboxane B2 (TXB2) was measured in urine samples by high-performance liquid chromatography-mass spectrometry and recalculated based on the creatinine concentration. The urine samples were collected the morning prior to PTA, immediately following PTA and the day after PTA. All of the study subjects were then observed for a period of 12 months. Urine samples w...
Source: J Physiol Pharmacol - May 31, 2016 Category: Drugs & Pharmacology Authors: Maga P, Sanak M, Jawien J, Rewerska B, Maga M, Wachsmann A, Koziej M, Gregorczyk-Maga I, Nizankowski R Tags: J Physiol Pharmacol Source Type: research

Extracranial giant cell arteritis: A narrative review.
Abstract A systematic literature search was performed to summarise current knowledge on extracranial giant cell arteritis (GCA), i.e. large-artery involvement in patients with or without clinically apparent temporal arteritis (cranial GCA). Extracranial GCA is increasingly recognised, both in patients with cranial GCA and with solitary extracranial GCA, due to increased awareness among physicians and development of modern imaging modalities. The literature on the pathogenesis and histopathology of extracranial GCA is scarce. It is considered to be similar to cranial GCA. Patients with solitary extracranial GCA oft...
Source: The Netherlands Journal of Medicine - May 31, 2016 Category: Journals (General) Authors: Lensen KD, Voskuyl AE, Comans EF, van der Laken CJ, Smulders YM Tags: Neth J Med Source Type: research

Revascularisation plus supervised exercise is superior to supervised exercise alone for the treatment of intermittent claudication
This study was a multicentre (10 sites), parallel-design randomised controlled trial of supervised exercise plus endovascular revascularisation versus supervised exercise alone for IC.4 Patients with IC and one or more stenotic lesions at the aortoiliac and/or femoropopliteal level amenable to endovascular therapy were eligible. Supervised exercise was provided 2–3 times per week for 30–45 min per session for 3 months and then continued...
Source: Evidence-Based Medicine - May 22, 2016 Category: Internal Medicine Authors: Vemulapalli, S. Tags: Clinical trials (epidemiology), Drugs: cardiovascular system, Stroke, Interventional cardiology, Radiology, Clinical diagnostic tests Therapeutics/Prevention Source Type: research

Efficacy and Safety of Transbrachial Access for Iliac Endovascular Interventions
Conclusion: Brachial artery access enables endovascular treatment of iliac artery disease in the majority of patients, although an adjunctive transfemoral access may be required. However, the high incidences of access site complications and cerebral events remain a significant limitation of the transbrachial approach.
Source: Journal of Endovascular Therapy - May 10, 2016 Category: Surgery Authors: Stavroulakis, K., Usai, M. V., Torsello, G., Schwindt, A., Stachmann, A., Beropoulis, E., Bisdas, T. Tags: Lower Limb Interventions Source Type: research

ACR Responds to MEDCAC on Peripheral Arterial Disease Care for Seniors
Reston, VA — The American College of Radiology (ACR) — as a member of a coalition of leading medical societies — provided peripheral arterial disease (PAD) treatment recommendations to the Medicare Evidence Development Coverage Advisory Committee (MEDCAC). In addition, the coalition called for continued research in how to provide the best care for U.S. seniors with lower extremity PAD. “Identifying quality health care and impacting the treatment of a disease that affects millions of Americans are critical,” said Anne C. Roberts, MD, FACR, ACR vice president and co-author of the multisociety r...
Source: American College of Radiology - April 10, 2016 Category: Radiology Source Type: news

Recurrent Spells of Unresponsiveness Secondary to Bilateral Carotid Stenosis Caused by Giant Cell Arteritis (P4.373)
Conclusions: The presence of bilateral carotid stenosis in patients with GCA is strongly associated with future risk of neurologic deficits. A vertebrobasilar steal syndrome may be a manifestation of bilateral, severe carotid stenosis. It may be difficult to separate atherosclerotic lesions from vasculitic lesions related to GCA, however, the presence of localized focal stenosis with relatively healthy arteries above and below the lesions may point to a vasculitic process. Rigorous attention should be given to modification of atherosclerotic risk factors as well as recognizing and treating the rare manifestation of GCA.Dis...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Wahba, M. Tags: Cerebrovascular Case Reports Source Type: research

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Development of parallel graft for arch lesions.
CONCLUSION: The results of parallel graft in the aortic arch are promising, but of major concern is still the high rate of Type I endoleaks as well as the neurological complication rate, most probably due to catheter manipulation in patients with severe atherosclerotic arch lesions. PMID: 27029672 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - March 30, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kolvenbach R, Rabin A, Karmeli R, Alpaslan A, Schwierz E Tags: J Cardiovasc Surg (Torino) Source Type: research

Surgical versus non-surgical treatment for lumbar spinal stenosis.
CONCLUSIONS: We have very little confidence to conclude whether surgical treatment or a conservative approach is better for lumbar spinal stenosis, and we can provide no new recommendations to guide clinical practice. However, it should be noted that the rate of side effects ranged from 10% to 24% in surgical cases, and no side effects were reported for any conservative treatment. No clear benefits were observed with surgery versus non-surgical treatment. These findings suggest that clinicians should be very careful in informing patients about possible treatment options, especially given that conservative treatment options...
Source: Cochrane Database of Systematic Reviews - January 29, 2016 Category: Journals (General) Authors: Zaina F, Tomkins-Lane C, Carragee E, Negrini S Tags: Cochrane Database Syst Rev Source Type: research

Stroke from an External Carotid: Lesion Pattern and Mechanisms
Traditionally, patients with symptomatic external carotid stenosis present with neck or face pain, retinal ischaemic symptoms or jaw claudication. and rarely as ipsilateral cerebrovascular events. In this present case, our patient suffered a stroke from a paradoxical embolism from the external carotid, without involvement of the internal carotid artery. A plaque ulceration of the external carotid’s origin was the cause of this cerebral emboli. Duplex ultrasound showed a pathological left external carotid, with a floating thrombus in the internal carotid.
Source: Annals of Vascular Surgery - January 20, 2016 Category: Surgery Authors: Kagan Nicolas, Lathelyse Hubert, Leclere Franck Marie, Marchand Etienne, Martinez Robert Source Type: research

Stroke in young adults and incidence rate in 280 patients according to their aetiological subtype.
CONCLUSIONS: Stroke in young adults is infrequent (6.1% of the total), but represents the highest frequency of cerebral infarcts of unusual aetiology (36%). We conclude that stroke in younger patients presents its own and differentiated clinical profile. PMID: 26726109 [PubMed - as supplied by publisher]
Source: Medicina Clinica - January 12, 2016 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

Endovascular repair of pseudoaneurysms after open surgery for aortic coarctation
CONCLUSIONS Endovascular treatment of post-coarctation pseudoaneurysms is feasible in elective and emergency cases, yielding durable results in the long term. Due to anatomical specifics, implantation may be challenging and requires careful procedural planning. On-site cardiothoracic surgery backup is essential in case open conversion is required.
Source: Interactive CardioVascular and Thoracic Surgery - December 26, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Kotelis, D., Bischoff, M. S., Rengier, F., Ruhparwar, A., Gorenflo, M., Böckler, D. Tags: Pericardium Adult Cardiac Source Type: research

Alternative management of the left subclavian artery in thoracic endovascular aortic repair for aortic dissection: a single-center experience
Conclusions The results of this study suggest that due to occurrence of complications, LSA should be preserved or revascularized to reduce complications and to improve patients’ quality of life.
Source: European Journal of Medical Research - May 31, 2015 Category: Research Source Type: research

Respiratory and otolaryngologic manifestations of giant cell arteritis.
CONCLUSIONS: It is important to recognize these atypical presentations because they may be the sole initial manifestation of the disease. Early suspicion and confirmation of the diagnosis of GCA can help to prevent more catastrophic consequences of unrecognized disease, including stroke and blindness. PMID: 26016768 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - May 30, 2015 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Alternative management of the left subclavian artery in thoracic endovascular aortic repair for aortic dissection: a single-center experience
The objective of this study was to present the follow-up results of covered or revascularized LSA during TEVAR. Methods: From January 2010 to August 2012, 109 consecutive patients were treated with TEVAR at the Department of Vascular Surgery, Changhai Hospital, for aortic dissection extending near the LSA. After evaluating the bilateral vertebral arteries, fifty-two LSAs were covered and not revascularized (covered group), while 57 LSAs were preserved (revascularized group). Complications were stratified according to the time of occurrence after surgery. Results: Emergency operations were more common (17.3 vs. 3.5 %, P = ...
Source: BioMed Central - May 30, 2015 Category: Journals (General) Authors: Lei ZhangQingsheng LuJian ZhouZaiping JingZhiqing ZhaoJunmin Bao Source Type: research