Subependymal Giant-cell Astrocytoma Masquerading as Restrictive Eating Disorder and Depression in an Adolescent
by Alicia Barnes, DO, MPH; Maggie M. Wang, BS; Jordan Feltes, BS; Je Ko, MD, PhD; and Miguel A. Guzman, MD Drs. Barnes and Ko are with the Department of Psychiatry, Saint Louis University School of Medicine in St. Louis, Missouri. Ms. Wang and Feltes are with the Saint Louis University School of Medicine in […] The post Subependymal Giant-cell Astrocytoma Masquerading as Restrictive Eating Disorder and Depression in an Adolescent appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - February 19, 2020 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Depression Early Release Articles Eating Disorders Psychiatry adolescent astrocytoma brain neoplasms Feeding and eating disorders Source Type: research

November-December 2019 Digital Edition
Click the cover below to access the November-December 2019 digital edition! The post November-December 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 11–12, November-December 2019
Dear Colleagues: Welcome to the November–December 2019 edition of Innovations in Clinical Neuroscience (ICNS). The issue begins with a case report by Diaz et al titled, “Use of Noninvasive Ventilation with Volume-assured Pressure Support for Treatment-refractory Myasthenia Gravis.” The authors share that a stepwise approach to therapy and use of immunosuppressive agents have led to […] The post Editorial Message and Issue Highlights–Vol. 16, No. 11–12, November-December 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Use of Noninvasive Ventilation with Volume-assured Pressure Support for Treatment-refractory Myasthenia Gravis
by MONTSERRAT DIAZ-ABAD, MD; NEVINS TODD, MD; LINDSAY ZILLIOX, MD; ANA SANCHEZ, MD; and CHARLENE HAFER-MACHO, MD Dr. Diaz-Abad and Dr. Todd are with the Department of Medicine, University of Maryland School of Medicine in Baltimore, Maryland. Drs. Zilliox, Sanchez, and Hafer-Macko are with the Department of Neurology, University of Maryland School of Medicine in […] The post Use of Noninvasive Ventilation with Volume-assured Pressure Support for Treatment-refractory Myasthenia Gravis appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Sleep Disorders Myasthenia gravis noninvasive ventilation respiratory failure sleep hypoventilation treatment-refractory volume-assured pressure support Source Type: research

Dismantling Fears Associated with Intellectual Disability Psychotherapy: An Evidence-based Practice
by Jessica A. Porcelan, MD; Katherine E. Caujolle-Alls, MD; and Julie P. Gentile, MD Drs. Porcelan, Caujolle-Alls, and Gentile are with the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Department editor Allison […] The post Dismantling Fears Associated with Intellectual Disability Psychotherapy: An Evidence-based Practice appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Mental Disorders Psychotherapy Rounds cognitive behavioral therapy in intellectual disability developmental disability motivational interviewing in intellectual disability psychotherapy in intellectual disability supportive psy Source Type: research

Improving Depression Management in Patients with Medical Illness Using Collaborative Care: Linking Treatment from the Inpatient to the Outpatient Setting
by Gabriel Edwards, MD, MPH; Teryl Nuckols, MD, MSHS; Nathalie Herrera, MD; Itai Danovitch, MD, MBA; and Waguih William IsHak, MD, FAPA Drs. Edwards, Herrera, Danovitch, and IsHak are with the Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center in Los Angeles, California. Dr. Nuckols is with the Division of General Internal Medicine, Cedars-Sinai […] The post Improving Depression Management in Patients with Medical Illness Using Collaborative Care: Linking Treatment from the Inpatient to the Outpatient Setting appeared first on Innovations in Clinical Neuroscience. (Source: Innovations...
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review care management care transitions collaborative care comorbid physical consult psychiatry depression health care organization and financing mental illness telemedicine value-based purchasing Source Type: research

A Look at Genetic Linkage between Clozapine-induced Agranulocytosis, Malignant Hyperthermia, Neuroleptic Malignant Syndrome, and Statin-induced Myopathy
by Nitin Pothen, MD; Shveta Kansal, MD; Theodor Rais, MD; Stacy Doumas, MD; and Ramon Solhkhah, MD Dr. Pothen and Dr. Kansal are with Ocean Medical Center, Hackensack Meridian Health in Brick, New Jersey. Dr. Rias is with Firelands Regional Health System-Sandusky in Sandusky, Ohio, and Mercy Health-St. Vincent Medical Center in Toledo, Ohio. Dr. […] The post A Look at Genetic Linkage between Clozapine-induced Agranulocytosis, Malignant Hyperthermia, Neuroleptic Malignant Syndrome, and Statin-induced Myopathy appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Medical Issues Review clozapine-induced agranulocytosis drug reaction malignant hyperthermia neuroleptic malignant syndrome statin-induced myopathy Source Type: research

A Review of the Pharmacological Management of Chronic Pain in Patients with Heart Failure
by Muhammad Hassan Majeed, MD; Ali Ahsan Ali, MD; Hafiza Ayesha Khalil, MD; Douglas Bacon, MD; and Hafiz Muhammad Imran, MD Dr. Majeed is with the Department of Anesthesiology and Critical Care Management, Johns Hopkins Hospital in Baltimore, Maryland. Dr. Ali is with the Department of Psychiatry, Icahn School of Medicine at Mount Sinai (Elmhurst) […] The post A Review of the Pharmacological Management of Chronic Pain in Patients with Heart Failure appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Pain Review chronic heart failure chronic pain nonsteroidal anti-inflammatory drugs (NSAIDs) pharmacology Source Type: research

Use of Brexanolone for Postpartum Depression
by Jonathan R. Scarff, MD Dr. Scarff is with the Behavioral Health Service Line, Kenner Army Health Clinic, in Fort Lee, Virginia. Funding: No funding was provided. Disclosures: Disclaimer: The views expressed in this article are those of the author and do not reflect official policy or position of the Kenner Army Health Clinic, the […] The post Use of Brexanolone for Postpartum Depression appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Review allopregnanolone brexanolone GABAA postpartum Source Type: research

Placental Barrier and Autism Spectrum Disorders: The Roles of Prolactin and Dopamine in the Developing Fetal Brain —Part II
by Atmaram Yarlagadda, MD; Ganesh Acharya, MD, PhD, FRCOG; Jayaprada Kasaraneni, MBBS; Christiane S. Hampe, PhD; and Anita H. Clayton, MD Dr. Yarlagadda is with the Department of Defense and the University of Virginia in Charlottesville, Virginia. Dr. Acharya is with the Karolinska Institutet in Solna, Sweden. Dr. Kasaraneni is with Texas Tech University in […] The post Placental Barrier and Autism Spectrum Disorders: The Roles of Prolactin and Dopamine in the Developing Fetal Brain—Part II appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Child Adol Mental Disorders Current Issue Study Protocol autism dopamine Placenta Prolactin Source Type: research

Navigating the ADA: What Clinicians Need to Know —Part One
by Donna Vanderpool, MBA, JD Ms. Vanderpool is the Vice President of Risk Management at Professional Risk Management Services in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk-management consulting company for healthcare providers. This ongoing column is dedicated to […] The post Navigating the ADA: What Clinicians Need to Know—Part One appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management ada Source Type: research

CNS Summit 2019 Abstract Supplement Digital Edition
Click the cover below to access the CNS Summit 2019 Abstract Supplement digital edition! The post CNS Summit 2019 Abstract Supplement Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

CNS Summit 2019 Abstract Supplement Digital Edition
Click the cover below to access the CNS Summit 2019 Abstract Supplement digital edition! (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 9–10, September-October 2019
Dear Colleagues: Welcome to the September–October 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a study titled, “Psychiatric Comorbidities in Adult Attention-deficit/Hyperactivity Disorder: Prevalence and Patterns in the Routine Clinical Setting.” In this surveillance study, Ohnishi et al assessed the prevalence of comorbid psychiatric disorders, evaluated relationships between comorbid psychiatric […] The post Editorial Message and Issue Highlights–Vol. 16, No. 9–10, September-October 2019 appeared first on Innovations in Clinical Neuroscience. (...
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 9–10, September-October 2019
Dear Colleagues: Welcome to the September–October 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a study titled, “Psychiatric Comorbidities in Adult Attention-deficit/Hyperactivity Disorder: Prevalence and Patterns in the Routine Clinical Setting.” In this surveillance study, Ohnishi et al assessed the prevalence of comorbid psychiatric disorders, evaluated relationships between comorbid psychiatric […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Psychiatric Comorbidities in Adult Attention-deficit/Hyperactivity Disorder: Prevalence and Patterns in the Routine Clinical Setting
by Takashi Ohnishi, MD, PhD; Hisanori Kobayashi, PhD; Tsutomu Yajima, MS; Takeshi Koyama, MS; and Kenichi Noguchi, PhD Drs. Ohnishi, Kobayashi, and Noguchi are with the Medical Affairs Division, Mr. Yajima is with the Quantitative Science Division, and Mr. Koyama is with the Drug Surveillance Department of the Research and Development Division of Janssen Pharmaceutical […] The post Psychiatric Comorbidities in Adult Attention-deficit/Hyperactivity Disorder: Prevalence and Patterns in the Routine Clinical Setting appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Adult attention deficit hyperactivity disorder comorbid disorders externalizing disorder internalizing disorder nosology Source Type: research

Psychiatric Comorbidities in Adult Attention-deficit/Hyperactivity Disorder: Prevalence and Patterns in the Routine Clinical Setting
by Takashi Ohnishi, MD, PhD; Hisanori Kobayashi, PhD; Tsutomu Yajima, MS; Takeshi Koyama, MS; and Kenichi Noguchi, PhD Drs. Ohnishi, Kobayashi, and Noguchi are with the Medical Affairs Division, Mr. Yajima is with the Quantitative Science Division, and Mr. Koyama is with the Drug Surveillance Department of the Research and Development Division of Janssen Pharmaceutical […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Adult attention deficit hyperactivity disorder comorbid disorders externalizing disorder internalizing disorder nosology Source Type: research

ACTing Like a Psychiatrist
by Nolan Carlile, DO; Jared S. Link, PsyD; Allison Cowan, MD; and Elizabeth G. Sarnoski, MD Drs. Carlile, Cowan, and Sarnoski are with Wright State University in Dayton, Ohio. Drs. Carlile, Sarnoski, and Link are with the U.S. Air Force at Wright-Patterson Air Force Base, Ohio. Funding: No funding was provided. Disclosures: The authors have […] The post ACTing Like a Psychiatrist appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Cognitive Behavioral Therapy Current Issue Psychiatry Psychotherapy Rounds acceptance ACT psychotherapy ACT therapy defusion values Source Type: research

ACTing Like a Psychiatrist
by Nolan Carlile, DO; Jared S. Link, PsyD; Allison Cowan, MD; and Elizabeth G. Sarnoski, MD Drs. Carlile, Cowan, and Sarnoski are with Wright State University in Dayton, Ohio. Drs. Carlile, Sarnoski, and Link are with the U.S. Air Force at Wright-Patterson Air Force Base, Ohio. Funding: No funding was provided. Disclosures: The authors have […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Cognitive Behavioral Therapy Current Issue Psychiatry Psychotherapy Rounds acceptance ACT psychotherapy ACT therapy defusion values Source Type: research

The Effect of Acutely Administered Propofol on Forced Swim Test Outcomes in Mice
by David G. Daniel, MD; Noah G. Daniel; Donald T. Daniel; Laura Copeland Flynn, MS; and Michael H. Allen, MD Dr. Daniel is with Bioniche Global Development, LLC in McLean, Virginia and the George Washington University in Washington DC. Mr. N. Daniel is with Dartmouth College in Hanover, New Hampshire. Mr. D. Daniel is with […] The post The Effect of Acutely Administered Propofol on Forced Swim Test Outcomes in Mice appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Drug Development Original Research Forced swim test mouse model propofol treatment-resistant depression Source Type: research

The Effect of Acutely Administered Propofol on Forced Swim Test Outcomes in Mice
by David G. Daniel, MD; Noah G. Daniel; Donald T. Daniel; Laura Copeland Flynn, MS; and Michael H. Allen, MD Dr. Daniel is with Bioniche Global Development, LLC in McLean, Virginia and the George Washington University in Washington DC. Mr. N. Daniel is with Dartmouth College in Hanover, New Hampshire. Mr. D. Daniel is with […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Drug Development Original Research Forced swim test mouse model propofol treatment-resistant depression Source Type: research

Correlation Between the Movement Disorder Society ’s Unified Parkinson’s Disease Rating Scale and Nonmotor Scales in Patients with Parkinson’s Disease
by Erika D. Driver-Dunckley, MD; Nan Zhang, MS; Holly A. Shill, MD; Shyamal H. Mehta, MD, PhD; Christine M. Belden, PsyD; Edward Y. Zamrini, MD; Kathryn Davis; Thomas G. Beach, MD, PhD; and Charles H. Adler, MD, PhD Drs. Driver-Dunckley, Mehta, and Adler are with the Department of Neurology of the Parkinson’s Disease and Movement […] The post Correlation Between the Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale and Nonmotor Scales in Patients with Parkinson’s Disease appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Neurology Original Research Parkinson's disease ESS MDS-UPDRS MSQ NPI-Q parkinson’s disease SCOPA-AUT Source Type: research

Correlation Between the Movement Disorder Society ’s Unified Parkinson’s Disease Rating Scale and Nonmotor Scales in Patients with Parkinson’s Disease
by Erika D. Driver-Dunckley, MD; Nan Zhang, MS; Holly A. Shill, MD; Shyamal H. Mehta, MD, PhD; Christine M. Belden, PsyD; Edward Y. Zamrini, MD; Kathryn Davis; Thomas G. Beach, MD, PhD; and Charles H. Adler, MD, PhD Drs. Driver-Dunckley, Mehta, and Adler are with the Department of Neurology of the Parkinson’s Disease and Movement […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Neurology Original Research Parkinson's disease ESS MDS-UPDRS MSQ NPI-Q parkinson’s disease SCOPA-AUT Source Type: research

Brexpiprazole as a New Serotonin –Dopamine Receptor Modulator: Considering the Clinical Relevance for Metabolic Parameters and Prolactin Levels
by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided for this study. Disclosures: The authors have no […] The post Brexpiprazole as a New Serotonin–Dopamine Receptor Modulator: Considering the Clinical Relevance for Metabolic Parameters and Prolactin Levels appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in C...
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Drug Development Original Research Schizophrenia antipsychotics aripiprazole brexpiprazole metabolism olanzapine paliperidone Prolactin Source Type: research

Brexpiprazole as a New Serotonin –Dopamine Receptor Modulator: Considering the Clinical Relevance for Metabolic Parameters and Prolactin Levels
by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine, Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine, Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided for this study. Disclosures: The authors have no […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Drug Development Original Research Schizophrenia antipsychotics aripiprazole brexpiprazole metabolism olanzapine paliperidone Prolactin Source Type: research

Is Transcranial Magnetic Stimulation Appropriate For Treating Adolescents with Depression?
by Puneet Narang, MD; Katelyn Madigan, BS; Simrat Sarai, MD; and Steven Lippmann, MD Dr. Narang is with the University of Minnesota and Regions Hospital, Minneapolis–St. Paul in Minneapolis, Minnesota. Ms. Madigan is with the University of Minnesota, Minneapolis–St. Paul in Minneapolis, Minnesota. Drs. Sarai and Lippmann are with the University of Louisville School of […] The post Is Transcranial Magnetic Stimulation Appropriate For Treating Adolescents with Depression? appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Child Adol Mental Disorders Current Issue Depression Review Suicidality Adolescent depression affective illness neurostimulation Transcranial magnetic stimulation Source Type: research

Is Transcranial Magnetic Stimulation Appropriate For Treating Adolescents with Depression?
by Puneet Narang, MD; Katelyn Madigan, BS; Simrat Sarai, MD; and Steven Lippmann, MD Dr. Narang is with the University of Minnesota and Regions Hospital, Minneapolis–St. Paul in Minneapolis, Minnesota. Ms. Madigan is with the University of Minnesota, Minneapolis–St. Paul in Minneapolis, Minnesota. Drs. Sarai and Lippmann are with the University of Louisville School of […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Child Adol Mental Disorders Current Issue Depression Review Suicidality Adolescent depression affective illness neurostimulation Transcranial magnetic stimulation Source Type: research

Psychopharmacology in Pediatric Mixed Anxiety Disorder: An Evidence-based Review
by Sadiq Naveed, MD; Afshan Naz Amray, MD; Nusrat Jahan, MD; Fatima Bilal Moti-wala, MD; and Muhammad Hassan Majeed, MD Dr. Naveed is with the University of Kansas Medical Center in Kansas City, Kansas. Dr. Amray is with Dow University of Health Sciences in Karachi, Pakistan. Dr. Jahan is with Rush University Medical Center in […] The post Psychopharmacology in Pediatric Mixed Anxiety Disorder: An Evidence-based Review appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Anxiety Disorders Child Adol Mental Disorders Current Issue Psychopharmacology Review pediatric pharmacotherapy psychotherapeutic treatment Source Type: research

Psychopharmacology in Pediatric Mixed Anxiety Disorder: An Evidence-based Review
by Sadiq Naveed, MD; Afshan Naz Amray, MD; Nusrat Jahan, MD; Fatima Bilal Moti-wala, MD; and Muhammad Hassan Majeed, MD Dr. Naveed is with the University of Kansas Medical Center in Kansas City, Kansas. Dr. Amray is with Dow University of Health Sciences in Karachi, Pakistan. Dr. Jahan is with Rush University Medical Center in […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Anxiety Disorders Child Adol Mental Disorders Current Issue Psychopharmacology Review pediatric pharmacotherapy psychotherapeutic treatment Source Type: research

Online Marketing: Risk Management Reminders
by Donna Vanderpool, MBA JD Ms. Vanderpool is the Vice President of Risk Management at Professional Risk Management Services in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for health care providers. This ongoing column is […] The post Online Marketing: Risk Management Reminders appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management online marketing Source Type: research

Online Marketing: Risk Management Reminders
by Donna Vanderpool, MBA JD Ms. Vanderpool is the Vice President of Risk Management at Professional Risk Management Services in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for health care providers. This ongoing column is […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management online marketing Source Type: research

CNS Summit 2019 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2019. The supplement is also available online by visiting […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Supplements Trial Methodology clinical trials CNS Summit Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 7–8, July-August 2019
Dear Colleagues: Welcome to the July–August 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a meta-analysis by Whitlock, Woodward, and Alexander titled, “Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.” Here, the authors investigated the accuracy of the popular theory that placebo […] The post Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies
by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United Kingdom. Mr. Woodward is an independent statistics consultant in Newmarket, United Kingdom. Dr. Alexander is with Takeda Pharmaceuticals International Company in Cambridge, Massachusetts. Funding: No […] The post Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Meta-analysis antidepressant effects clinical trials orthogonal regression placebo additivity placebo response Source Type: research

High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure
by Megan K. Skelly, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Claudia Lee, MD Drs. Skelly, Demler, and Lee are with the State University at Buffalo (SUNY) School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice in Buffalo, New York and Drs. Demler and Lee are also with New York […] The post High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms Psychopharmacology clozapine seizure withdrawal Source Type: research

Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child
by Catherine Butz, PhD; Cindy Iske, MS, OTR/L; Natalie Truba, PhD; and Kristen Trott, PhD Drs. Butz, Truba, and Trott are with the Psychology Department, and Ms. Iske is Program Manager for the Rehabilitation Unit, Physical Medicine and Rehabilitation Service, at Nationwide Children’s Hospital in Columbus, Ohio. Funding: No funding was provided. Disclosures: The authors […] The post Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Movement Disorders Original Research conversion mobility rehabilitation short-term Source Type: research

The Very Important Patient
by Danielle Gainer, MD, and Allison E. Cowan, MD Dr. Gainer is Assistant Professor, and Dr. Cowan is Associate Professor, in the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Department editors: Julie […] The post The Very Important Patient appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Practice Management Psychotherapy Rounds countertransference difficult patient entitled patient influential patient physician patient VIP patient Source Type: research

Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy
by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine at Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine at Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided. Disclosures: The authors have no conflicts […] The post Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Psychiatry Apical ballooning syndrome hyponatremia lamotrigine syndrome of inappropriate secretion of antidiuretic hormone takotsubo cardiomyopathy Source Type: research

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer ’s Disease Stage
by Yue Deng, MSc; Brianna M. Marsh, BSc student; and Jackob Moskovitz, PhD Mr. Deng, Ms. Marsh, and Dr. Moskovitz are with the Department of Pharmacology and Toxicology at the School of Pharmacy, University of Kansas in Lawrence, Kansas. Funding: Support for the studies were provided by the KU ADC P30 AG035982 and the Landon […] The post Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Alzheimer's Disease Cognition Current Issue Original Research Antioxidants blood-plasma methionine oxidation Source Type: research

Risk Management: Communicating with Family Members and Other Caregivers
by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […] The post Risk Management: Communicating with Family Members and Other Caregivers appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management caregivers communication Source Type: research

Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube
Dear Editor: Social media platforms are increasingly used to disseminate health promotion and patient education.1–5 Impressions click-through rate (CTR) is the number of clicks on a health promotion and/or patient education ad, divided by the times the ad was shown on a social media platform. A recent study explored the practicality of Facebook advertising to […] The post Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Dementia Letters to the Editor click-through rate youtube Source Type: research

ICNS July-August 2019 Digital Edition
Click the cover below to access the July-August 2019 digital edition of Innovations in Clinical Neuroscience! The post ICNS July-August 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

The Neuroscience Report —Vol. 54 (May 17, 2019): Migraines
Welcome to The Neuroscience Report, where we highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Migraines 5 Journal Articles Understanding the nature of psychiatric comorbidity in migraine: a systematic […] The post The Neuroscience Report—Vol. 54 (May 17, 2019): Migraines appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 17, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: The Neuroscience Report migraines Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 5–6, May-June 2019
Dear Colleagues: Welcome to the May-June 2019 edition of Innovations in Clinical Neuroscience (ICNS). In this issue, we revisit the topic of postpartum depression in men with a review article of the same name by Scarff. Here, the author describes the symptoms, risk factors, and treatment options for this disorder in men, and highlights the […] The post Editorial Message and Issue Highlights–Vol. 16, No. 5–6, May-June 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Source Type: research

Postpartum Depression in Men
by Jonathan R. Scarff, MD Dr. Scarff is a psychiatrist with the Behavioral Health Service Line at Kenner Army Health Clinic in Fort Lee, Virginia. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Abstract: Postpartum depression (PPD) is often defined as an episode […] The post Postpartum Depression in Men appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Psychiatry Review antidepressant fathers postpartum psychotherapy Source Type: research

Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study
by Leslie Citrome, MD, MPH; Stephanie S. O’Malley, PhD; David McDonnell, MD; Ying Jiang, PhD; Adam C. Simmons, MPH; Mark P. Berry; and Lauren E. DiPetrillo, PhD Dr. Citrome is with the Department of Psychiatry and Behavioral Sciences at New York Medical College in Valhalla, New York. Dr. O’Malley is with the Department of Psychiatry […] The post Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Drug Development Schizophrenia Study Protocol alcohol use disorder ALKS 3831 olanzapine samidorphan Source Type: research

Exploring the Effectiveness of Team-based Enablement Interventions to Improve Antibiotic Prescribing within a Psychiatric Hospital
by Emily E. Leppien, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Eileen Trigoboff, RN, PMHCNS-BC, DNS, DABFN Dr. Leppien is with the Binghamton University School of Pharmacy and Pharmaceutical Sciences and Lourdes Hospital Center for Pain and Wellness in Binghamton, New York. Drs. Demler and Trigoboff are with the Buffalo Psychiatric […] The post Exploring the Effectiveness of Team-based Enablement Interventions to Improve Antibiotic Prescribing within a Psychiatric Hospital appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Psychiatry antibiotic prescribing antimicrobial stewardship educational strategies prescribing practices provider education psychiatric inpatients Source Type: research

Adult Neurogenesis in Humans: A Review of Basic Concepts, History, Current Research, and Clinical Implications
by Ashutosh Kumar, MD; Vikas Pareek, PhD; Muneeb A. Faiq, PhD; Sanjib K. Ghosh, MD; and Chiman Kumari, MD Drs. Kumar and Ghosh are with the Department of Anatomy at the All India Institute of Medical Sciences (AIIMS) in Patna, India. Dr. Pareek is with the Computational Neuroscience and Neuroimaging Division at National Brain Research […] The post Adult Neurogenesis in Humans: A Review of Basic Concepts, History, Current Research, and Clinical Implications appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Neurology Review Adult human neurogenesis aging hippocampus neuropsychiatric disorders neurorestoration olfactory bulb Source Type: research

Play Therapy: An Illustrative Case
by Kimberly Senko, BS, and Bethany Harper, MD Ms. Senko is a fourth-year medical student at Wright State University Boonshoft School of Medicine, and Dr. Harper is Assistant Professor and Director of Medical Student Education in the Department of Psychiatry at Wright State University Boonshoft School of Medicine in Dayton, Ohio. Funding: No funding was […] The post Play Therapy: An Illustrative Case appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychotherapy Rounds child and adolescent therapy Child psychiatry child psychotherapy counseling play therapy Source Type: research

A Case of Peripartum Obsessive-Compulsive Disorder: The Potential Role of Corticosteroids, Gonadal Steroids, and the Neuropeptide Oxytocin in its Pathogenesis
by David R. Spiegel, MD; Kathyrn Sommese, MD; Anastasia Turenkov, MD; and Niels Naimon, MD Drs. Spiegel, Sommese, Turenkov, and Naimon are with the Department of Psychiatry and Behavioral Sciences at Eastern Virginia Medical School in Norfolk, Virginia. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content […] The post A Case of Peripartum Obsessive-Compulsive Disorder: The Potential Role of Corticosteroids, Gonadal Steroids, and the Neuropeptide Oxytocin in its Pathogenesis appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Impulse Control Disorders Psychiatry gonadal steroids obsessive-compulsive disorder (OCD) oxytocin Peripartum Source Type: research