Risk Management: Communicating with Family Members and Other Caregivers
by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […] The post Risk Management: Communicating with Family Members and Other Caregivers appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management caregivers communication Source Type: research

Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube
Dear Editor: Social media platforms are increasingly used to disseminate health promotion and patient education.1–5 Impressions click-through rate (CTR) is the number of clicks on a health promotion and/or patient education ad, divided by the times the ad was shown on a social media platform. A recent study explored the practicality of Facebook advertising to […] The post Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Dementia Letters to the Editor click-through rate youtube Source Type: research

ICNS July-August 2019 Digital Edition
Click the cover below to access the July-August 2019 digital edition of Innovations in Clinical Neuroscience! The post ICNS July-August 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

The Neuroscience Report —Vol. 54 (May 17, 2019): Migraines
Welcome to The Neuroscience Report, where we highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Migraines 5 Journal Articles Understanding the nature of psychiatric comorbidity in migraine: a systematic […] The post The Neuroscience Report—Vol. 54 (May 17, 2019): Migraines appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 17, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: The Neuroscience Report migraines Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 5–6, May-June 2019
Dear Colleagues: Welcome to the May-June 2019 edition of Innovations in Clinical Neuroscience (ICNS). In this issue, we revisit the topic of postpartum depression in men with a review article of the same name by Scarff. Here, the author describes the symptoms, risk factors, and treatment options for this disorder in men, and highlights the […] The post Editorial Message and Issue Highlights–Vol. 16, No. 5–6, May-June 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Source Type: research

Postpartum Depression in Men
by Jonathan R. Scarff, MD Dr. Scarff is a psychiatrist with the Behavioral Health Service Line at Kenner Army Health Clinic in Fort Lee, Virginia. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Abstract: Postpartum depression (PPD) is often defined as an episode […] The post Postpartum Depression in Men appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Psychiatry Review antidepressant fathers postpartum psychotherapy Source Type: research

Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study
by Leslie Citrome, MD, MPH; Stephanie S. O’Malley, PhD; David McDonnell, MD; Ying Jiang, PhD; Adam C. Simmons, MPH; Mark P. Berry; and Lauren E. DiPetrillo, PhD Dr. Citrome is with the Department of Psychiatry and Behavioral Sciences at New York Medical College in Valhalla, New York. Dr. O’Malley is with the Department of Psychiatry […] The post Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Drug Development Schizophrenia Study Protocol alcohol use disorder ALKS 3831 olanzapine samidorphan Source Type: research

Exploring the Effectiveness of Team-based Enablement Interventions to Improve Antibiotic Prescribing within a Psychiatric Hospital
by Emily E. Leppien, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Eileen Trigoboff, RN, PMHCNS-BC, DNS, DABFN Dr. Leppien is with the Binghamton University School of Pharmacy and Pharmaceutical Sciences and Lourdes Hospital Center for Pain and Wellness in Binghamton, New York. Drs. Demler and Trigoboff are with the Buffalo Psychiatric […] The post Exploring the Effectiveness of Team-based Enablement Interventions to Improve Antibiotic Prescribing within a Psychiatric Hospital appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Psychiatry antibiotic prescribing antimicrobial stewardship educational strategies prescribing practices provider education psychiatric inpatients Source Type: research

Adult Neurogenesis in Humans: A Review of Basic Concepts, History, Current Research, and Clinical Implications
by Ashutosh Kumar, MD; Vikas Pareek, PhD; Muneeb A. Faiq, PhD; Sanjib K. Ghosh, MD; and Chiman Kumari, MD Drs. Kumar and Ghosh are with the Department of Anatomy at the All India Institute of Medical Sciences (AIIMS) in Patna, India. Dr. Pareek is with the Computational Neuroscience and Neuroimaging Division at National Brain Research […] The post Adult Neurogenesis in Humans: A Review of Basic Concepts, History, Current Research, and Clinical Implications appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Neurology Review Adult human neurogenesis aging hippocampus neuropsychiatric disorders neurorestoration olfactory bulb Source Type: research

Play Therapy: An Illustrative Case
by Kimberly Senko, BS, and Bethany Harper, MD Ms. Senko is a fourth-year medical student at Wright State University Boonshoft School of Medicine, and Dr. Harper is Assistant Professor and Director of Medical Student Education in the Department of Psychiatry at Wright State University Boonshoft School of Medicine in Dayton, Ohio. Funding: No funding was […] The post Play Therapy: An Illustrative Case appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychotherapy Rounds child and adolescent therapy Child psychiatry child psychotherapy counseling play therapy Source Type: research

A Case of Peripartum Obsessive-Compulsive Disorder: The Potential Role of Corticosteroids, Gonadal Steroids, and the Neuropeptide Oxytocin in its Pathogenesis
by David R. Spiegel, MD; Kathyrn Sommese, MD; Anastasia Turenkov, MD; and Niels Naimon, MD Drs. Spiegel, Sommese, Turenkov, and Naimon are with the Department of Psychiatry and Behavioral Sciences at Eastern Virginia Medical School in Norfolk, Virginia. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content […] The post A Case of Peripartum Obsessive-Compulsive Disorder: The Potential Role of Corticosteroids, Gonadal Steroids, and the Neuropeptide Oxytocin in its Pathogenesis appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Impulse Control Disorders Psychiatry gonadal steroids obsessive-compulsive disorder (OCD) oxytocin Peripartum Source Type: research

Russian Stimulation/Functional Electrical Stimulation in the Treatment of Foot Drop Resulting from Lumbar Radiculopathy: A Case Series
by Tina J. Wang, MD; Kyungje Sung; Marilyn Wilburn, MD; and Jace Allbright, DPT Dr. Wang is Attending Physician at Loma Linda Veterans Administration Hospital in the Department of Physical Medicine and Rehabilitation in Redlands, California. Ms. Sung is a Medical Student at Loma Linda University School of Medicine in Loma Linda, California. Dr. Wilburn […] The post Russian Stimulation/Functional Electrical Stimulation in the Treatment of Foot Drop Resulting from Lumbar Radiculopathy: A Case Series appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Series Current Issue Pain foot drop Functional electrical stimulation lumbar radiculopathy Russian stimulation Source Type: research

Risk Management: Establishing the Psychiatrist –Patient Relationship: When is a Duty of Care Owed?
by Ann McNary, JD Ms. McNary is a Senior Risk Manager at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […] The post Risk Management: Establishing the Psychiatrist–Patient Relationship: When is a Duty of Care Owed? appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management patient-psychiatrist relationship Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 3–4, March-April 2019
Dear Colleagues: Welcome to the March–April 2019 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a Psychotherapy Rounds submission titled, “Addiction Disorder Considerations in Patients Seeking Psychotherapy,” by Stubbs and Merrill. It is not uncommon for a patient with a psychiatric disorder to present with a comorbid substance use disorder, and […] The post Editorial Message and Issue Highlights–Vol. 16, No. 3–4, March-April 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Addiction Disorder Considerations for Patients Seeking Psychotherapy
by Kimberly Stubbs, MD, and Brian M. Merrill, MD, MBA Dr. Stubbs is Clinical Chief Resident, and Dr. Merrill is Assistant Professor and Director of Community Psychiatry at Wright State University Boonshoft School of Medicine in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content […] The post Addiction Disorder Considerations for Patients Seeking Psychotherapy appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychology Psychotherapy Rounds addiction addiction treatment counseling evidence based practices substance use disorders Source Type: research

The Pathophysiology of Marijuana-induced Encephalopathy and Possible Epilepsy after Ingestion in Children: A Case Series
by Alister Carvalho, MBBS, and Tracy Evans-Gilbert, DM, MPH, CTropMed® Drs. Carvalho and Evans-Gilbert are with the Department of Pediatrics at the Cornwall Regional Hospital in Montego Bay, Jamaica. Dr. Evans-Gilbert is also with the University of the West Indies, Western Campus, in Montego Bay, Jamaica. Funding: No funding was provided. Disclosures: The authors have […] The post The Pathophysiology of Marijuana-induced Encephalopathy and Possible Epilepsy after Ingestion in Children: A Case Series appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Series Current Issue Epilepsy Neurologic Systems and Symptoms Children marijuana seizures toxicology Source Type: research

Panic Attacks in Hyperaldosteronism
by Tiffany Y. Lin, MD; Rebecca M. Hedrick, MD; and Waguih William IsHak, MD, FAPA Drs. Lin and IsHak are with the David Geffen School of Medicine at University of California–Los Angeles in Los Angeles, California. Drs. Hedrick and IsHak are with Department of Psychiatry and Behavioral Neurosciences at Cedars-Sinai Medical Center in Los Angeles, […] The post Panic Attacks in Hyperaldosteronism appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms adrenal adenoma panic attack panic disorder Primary hyperaldosteronism Source Type: research

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis
by Laetitia Pouzol, MSc, PharmD; Luca Piali, PhD; Claude CA Bernard, PhD; Marianne M. Martinic, PhD; Beat Steiner, PhD; and Martine Clozel, MD Drs. Pouzol and Clozel were with Actelion Pharmaceuticals Ltd. in Allschwil, Switzerland, at the time of this research, and are presently with Idorsia Pharmaceuticals Ltd. in Allschwil, Switzerland. Dr. Piali was with […] The post Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Multiple Sclerosis Original Research combination therapy dimethyl fumarate (DMF) disease activity Experimental autoimmune encephalomyelitis (EAE) multiple sclerosis (MS) sphingosine-1-phosphate Source Type: research

The Top Three Things to Know about the Top Three Risk Management Issues
by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. Innov Clin Neurosci. 2019;16(3–4):31–32 This ongoing column is dedicated […] The post The Top Three Things to Know about the Top Three Risk Management Issues appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management Source Type: research

March-April 2019 Digital Edition
Click the cover below to access the March-April 2019 digital edition of Innovations in Clinical Neuroscience! The post March-April 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - March 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

January-February 2019 Digital Edition
Click the cover below to access the January-February 2019 digital edition of Innovations in Clinical Neuroscience! The post January-February 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 1–2, January-February 2019
Dear Colleagues: Welcome to the January–February 2019 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a review article by Yeo et al titled, “Virtual Reality Neurorehabilitation for Mobility in Spinal Cord Injury: A Structured Review.” Here, investigators conducted a literature review and reported that VR therapy has resulted in significant improvements […] The post Editorial Message and Issue Highlights–Vol. 16, No. 1–2, January-February 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Source Type: research

Virtual Reality Neurorehabilitation for Mobility in Spinal Cord Injury: A Structured Review
by Elizabeth Yeo, BS; Brian Chau, MD; Bradley Chi, BS; David E. Ruckle, BS; and Phillip Ta, MD Ms. Yeo, Dr. Chau, Mr. Chi, and Dr. Ta are with the Department of Physical Medicine & Rehabilitation at Loma Linda University Health Department in Loma Linda, California. Mr. Ruckle is with Loma Linda University School of […] The post Virtual Reality Neurorehabilitation for Mobility in Spinal Cord Injury: A Structured Review appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Movement Disorders Review Technology augmented reality mobility paraplegia quadriplegia spinal cord injury tetraplegia virtual reality Source Type: research

Exploring the Potential Psychiatric Implications of Astronomical Phenomena
by Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; Michaela Camille Lysogorski, PharmD; and Eileen Trigoboff, RN, RMHCNS-BC, DNS, DABFN Drs. Demler and Trigoboff are with the University of Buffalo, School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice, in Buffalo, New York, University of Buffalo, School of Medicine, Department of Psychiatry in Buffalo, […] The post Exploring the Potential Psychiatric Implications of Astronomical Phenomena appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Psychiatry behavior Eclipse lunar restraint Seclusion solar Source Type: research

Brain Imaging in New Onset Psychiatric Presentations
by Evelyne Baroud, MD; Roula Hourani, MD; and Farid Talih, MD Drs. Baroud and Talih are with the Department of Psychiatry, American University of Beirut Medical Center in Beirut, Lebanon. Dr. Hourani is with the Department of Diagnostic Radiology, American University of Beirut Medical Center in Beirut, Lebanon. FUNDING: No funding was provided. DISCLOSURES: The […] The post Brain Imaging in New Onset Psychiatric Presentations appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Series Current Issue Psychiatry neuroimaging neuropsychiatry psychiatric disorders psychosis Source Type: research

Synthetic Cannabinoids —”Spice” Can Induce a Psychosis: A Brief Review
by Rajashekar Reddy Yeruva, MD; Hema Madhuri Mekala, MD; Meesha Sidhu MD; and Steven Lippmann, MD Drs. Yeruva and Lippmann are with the University of Louisville School of Medicine in Louisville, Kentucky. Drs. Mekala and Sidhu are with Griffin Memorial Hospital in Norman, Oklahoma. Funding: No funding was provided. Disclosures: The authors have no conflicts […] The post Synthetic Cannabinoids—”Spice” Can Induce a Psychosis: A Brief Review appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychopharmacology Review adverse events K2 long-term outcomes psychosis schizophrenia Spice synthetic cannabinoids Source Type: research

Hot Topics in Neuroscience: Marijuana for Parkinson ’s Disease?
by Diksha Mohanty, MD, and Steven Lippmann, MD Dr. Mohanty is Research Scholar and Dr. Lippmann is Emeritus Professor at the University of Louisville School of Medicine in Louisville, Kentucky. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Abstract: Marijuana is popular in […] The post Hot Topics in Neuroscience: Marijuana for Parkinson’s Disease? appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Hot Topics in Neuroscience Neurology Parkinson's disease Psychopharmacology bradykinesia Cannabis marijuana medical marijuana motor symptoms parkinsonism parkinson’s disease rigidity stiffness tremor Source Type: research

Research to Practice: The Effect of Early Life Stress on Adult Psychiatric Disorders
by Steven D. Targum, MD, and Charles B. Nemeroff, MD, PhD Dr. Targum is Scientific Director with CRF-Bracket in Boston, Massachusetts. Dr. Nemeroff is Professor of Psychiatry and Director of the Institute of Early Life Adversity Research at Dell Medical School, The University of Texas at Austin in Austin, Texas. Funding: No funding was provided. […] The post Research to Practice: The Effect of Early Life Stress on Adult Psychiatric Disorders appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychiatry Research to Practice adult psychiatric disorder childhood abuse Early life stress major depressive disorder Source Type: research

Risk Management: HIPAA Compliance —A Common Sense Approach
by Donna Vanderpool, MBA, JD Ms. Vanderpool is Vice President at PRMS, Inc. in Arlington, Virginia. This ongoing column is dedicated to providing information to our readers on managing legal risks associated with medical practice. We invite questions from our readers. The answers are provided by PRMS, Inc. (www.prms.com), a manager of medical professional liability […] The post Risk Management: HIPAA Compliance—A Common Sense Approach appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management compliance HIPAA Source Type: research

Letter to the Editor: Rethinking the robotic rehabilitation pathway for people with amyotrophic lateral sclerosis: a need for clinical trials
By Rocco Salvatore Calabrò, MD, PhD; Simona Portaro, MD, PhD; Alfredo Manuli, MSc; Antonino Leo, MSc; Antonino Naro, MD, PhD; and Alessia Bramanti, PhD IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy Funding/financial disclosures. The author has no conflict of interest relevant to the content of this letter. No funding was received for the preparation of […] The post Letter to the Editor: Rethinking the robotic rehabilitation pathway for people with amyotrophic lateral sclerosis: a need for clinical trials appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - January 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Devices Letters to the Editor Neurology Technology Amyotrophic lateral sclerosis neurodegenerative disease Robotic neurorehabilitation Source Type: research

Editorial Message and Issue Highlights –Vol. 15, No. 11–12, November-December 2018
Dear Colleagues: Welcome to the November–December issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with an article by Aboraya et al titled “Measurement-based Care in Psychiatry—Past, Present, and Future.” Here the authors define and describe measurement-based care (MBC) in psychiatry as well discuss the research supporting its use in clinical practice. Barriers […] The post Editorial Message and Issue Highlights–Vol. 15, No. 11–12, November-December 2018 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Measurement-based Care in Psychiatry — Past, Present, and Future
by Ahmed Aboraya, MD, Dr.PH; Henry A. Nasrallah, MD; Daniel E. Elswick, MD; Ahmed Elshazly, MD; Nevine Estephan, MD; Dalia Aboraya, BA; Seher Berzingi; Josleen Chumbers; Aara Berzingi, BA; John Justice, MD; Jawad Zafar, DO; and Sheena Dohar, MD Dr. Aboraya is Chief of Psychiatry at William R. Sharpe, Jr. Hospital, Clinical Professor of Psychiatry […] The post Measurement-based Care in Psychiatry— Past, Present, and Future appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychiatry assessment assessment tool clinical trial Measurement-based care (MBC) outcomes measures psychopathology rating scale reliability Standard for Clinicians’ Interview in Psychiatry (SCIP) validity Source Type: research

Validation of an Equation Model to Predict Intracranial Pressure in Clinical Studies
by Niro Kasahara, MD; Mateus L. Matuoka, MD; Katia S. Santos, MD; Natasha F.S. Cruz, MD; Alvaro R. Martins, MD; and Stanley Nigro, MD Drs. Kasahara, Matuoka, Santos, and Cruz are with the Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo in Sao Paulo, Brazil. Dr. Kasahara is also with Santa […] The post Validation of an Equation Model to Predict Intracranial Pressure in Clinical Studies appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research Scales cerebrospinal fluid pressure clinical study clinical trial Glaucoma measurement tool translaminar pressure trial methodology Source Type: research

Lithium Suicide Prevention: A Brief Review and Reminder
by Simrat Kaur Sarai, MD; Hema Madhuri Mekala, MD; and Steven Lippmann, MD Drs. Sarai and Mekala are research scholars and Dr. Lippmann is Emeritus Professor for the Department of Psychiatry and Behavioral Sciences at University of Louisville School of Medicine in Louisville, Kentucky. Funding: No funding was provided. Disclosures: The authors have no conflicts […] The post Lithium Suicide Prevention: A Brief Review and Reminder appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Psychiatry Review Lithium pharmacotherapy risk of suicide suicidal ideas suicide prevention Source Type: research

Extreme Ends of Pain Sensitivity in SCN9A Mutation Variants: Case Report and Literature Review
by Muhammad Hassan Majeed, MD; Muhammad Ubaidulhaq, MD; Anesh Rugnath, MD; and Ike Eriator, MD Dr. Majeed is Attending Psychiatrist with the Department of Psychiatry at Natchaug Hospital in Norwich, Connecticut. Dr. Ubaidulhaq is Pain Medicine Fellow with the Department of Anesthesiology at University of Mississippi Medical Center in Jackson, Mississippi. Dr. Rugnath is Attending […] The post Extreme Ends of Pain Sensitivity in SCN9A Mutation Variants: Case Report and Literature Review appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Review Current Issue Neurology CIP Congenital insensitivity to pain hereditary sensory and autonomic neuropathy Type IID HSAN IID SCN9A mutation Source Type: research

It ’s Nice to Be Nice, But … A Little Risk Management Can Go a Long Way in Reducing Your Liability Risk
by Donna Vanderpool, MBA, JD Ms. Vanderpool is Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. Innov Clin Neurosci. 2018;15(11–12):36–38 This ongoing column is dedicated to providing […] The post It’s Nice to Be Nice, But…A Little Risk Management Can Go a Long Way in Reducing Your Liability Risk appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management psychiatry Source Type: research

Letter to the Editor: When “ Cure ” becomes “ Care ” in Robotic Neurorehabilitation: The Critical Role of Nurses in a Novel Sicilian Multidisciplinary Approach
By Alfredo Manuli, MSc, and Rocco Salvatore Calabrò, MD, PhD Funding/financial disclosures. The authors have no conflicts of interest relevant to the content of this letter. No funding was received for the preparation of this letter. Innov Clin Neurosci. 2018;15(11–12):11–12 Dear Editor: The goal of rehabilitation is to assist individuals with disability and/or chronic illness in […] The post Letter to the Editor: When “Cure” becomes “Care” in Robotic Neurorehabilitation: The Critical Role of Nurses in a Novel Sicilian Multidisciplinary Approach appeared first on Innov...
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Letters to the Editor Technology Robotic neurorehabilitation Source Type: research

Letter to the Editor: The Ever-changing Landscape of the Opioid Crisis: Fentanyl and its Analogs
By Adegboyega Oyemade, MD, FAPA Funding/financial disclosures. The author has no conflict of interest relevant to the content of this letter. No funding was received for the preparation of this letter. Innov Clin Neurosci. 2018;15(11–12):11–12 Dear Editor: Fentanyl was created in 1960 as an intravenous surgical anesthetic (Sublimaze®, Janssen Pharmaceuticals Inc.), which is 50 to 100 […] The post Letter to the Editor: The Ever-changing Landscape of the Opioid Crisis: Fentanyl and its Analogs appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - November 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Letters to the Editor Pain fentanyl opioids Source Type: research

CNS Summit 2018 Abstract Supplement Digital Edition
Click the cover below to access the CNS Summit 2018 Abstract Supplement digital edition! The post CNS Summit 2018 Abstract Supplement Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 30, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

CNS Summit 2018 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2018. The supplement is also available online by visiting […] The post CNS Summit 2018 Abstracts of Poster Presentations appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 30, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Supplements clinical trials CNS Summit Source Type: research

Mobile Technology
A model for researchers to engage in suicide prevention Presenters: Hendry P,1 Armstrong K,2 Barag J,2 Fowler C,3 Gutierrez N,4, Harkavy-Friedman J,5 Perez E,3 Saillard J,6 Vanover K,6 and Kramer L7 Affiliations: 1Mental Health America, Alexandria, Virginia; 2Premier Research, Durham, North Carolina; 3Otsuka, Princeton, New Jersey; 4Woodland Research Northwest, Rogers, Arkansas; 5American Foundation for Suicide […] The post Mobile Technology appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 27, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Investigative Drug Compounds/Therapies
*Differential treatment effects of TNX- 102 SL, a sublingual formulation of cyclobenzaprine, on dissociative symptoms of derealization and depersonalization in a military-related PTSD population: retrospective analysis of a double-blind randomized study** Presenters: Sullivan GM Affiliations: Tonix Pharmaceuticals, Inc Objective: Dissociative symptoms are associated with trauma disorders including posttraumatic stress disorder (PTSD). This is retrospective analysis […] The post Investigative Drug Compounds/Therapies appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Trial Protocol
Evaluation of collecting human emotions and if it could provide valuable evidence in clinical trials Presenters: Yamamoto R Affiliation: ERT Objective: The goal is to present a pilot project evaluating passively collected emotional data during clinical trials to determine its usefulness in supplementing traditional endpoint data. Design: The 11-person study combined the Columbia Suicide Severity […] The post Trial Protocol appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Rater Assessment And Training
Interrater reliability of the Protokinetics Movement Analysis Software and the Zeno Walkway during Four Step Square Test in individuals with Parkinson’s disease Presenters: Boddy A, Andrea C, Lomaglio M, Murphy J, and Perry L Affiliations: University of St. Augustine and S.T.A.R.S Rehab Objective: There is a growing interest in understanding postural instability in individuals with […] The post Rater Assessment And Training appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Placebo Response
Classical and quantum machine learning applied to predicting placebo response For clinical trials in bipolar disorder: recent results Presenters: Geraci J,1,2Wong B,1 Ziauddin J,1 Jain S,1,3 Leonczyk P,1 and Bishop KI4 Affiliations: 1NetraMark Corp, Toronto, Ontario, Canada; 2Department of Molecular Medicine, Queen’s University, Kingston, Ontario, Canada; 3University of Toronto, Toronto, Ontario, Canada; 4Global Pharma Consultancy, […] The post Placebo Response appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Early Indentification, Predictive Tools, And Imaging
Computerized gait analysis of dual tasks to improve eligibility and outcomes for Alzheimer’s disease clinical trials Presenters: Rosenfeld A, Tolea MI, and Galvin JE Affiliations: Comprehensive Center for Brain Health, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida Objective: Clinical trials in Alzheimer’s disease are expanding to test compounds in the […] The post Early Indentification, Predictive Tools, And Imaging appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Patient Recruitment
Impact and return on investment of patient recruitment campaign in a clinical trial of patients with opioid use disorder Presenters: Ramos J,1 Carter D,1 Romanello S,2 Miller M,3 and Martin W1 Affiliations: 1Alkermes, Inc.; 2PriMedia; 3StudyKIK Background: ALK6428-A302 was a Phase III clinical trial that evaluated the efficacy, safety, and tolerability of low doses of […] The post Patient Recruitment appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Patient Assessment
Do the symptoms that drive the CGI vary by geography? Presenter: Daniel DG and Kott A Affiliation: CRF Bracket Background/Objective: We have previously demonstrated regional differences in measurement of psychiatric symptoms. Global clinical trials in schizophrenia pool data using the Clinical Global Impression (CGI) to assess overall severity of illness. We hypothesized that the symptom […] The post Patient Assessment appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Digital Tools And Technology
Agile development of a prescription digital therapeutic for patients with schizophrenia Presenters: Campellone TR, Smayda KE, and Maricich YA Affiliations: Pear Therapeutics, Boston, Massachusetts Objective: With software-based “digital” therapeutic interventions, product development is agile and data-driven, allowing for continuous product refinement. Compared to existing models of therapeutic development, this approach allows for more rapid clinical […] The post Digital Tools And Technology appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 26, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

Editorial Message and Issue Highlights –Vol. 15, No. 9–10, September-October 2018
Dear Colleagues: Welcome to the September–October 2018 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a systematic review by Bart et al titled, “The Assessment and Measurement of Wellness in the Clinical Medical Setting: A Systematic Review.” Here, investigators reviewed the published literature in an attempt to answer the following: 1) […] The post Editorial Message and Issue Highlights–Vol. 15, No. 9–10, September-October 2018 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - October 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research