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Author Guidelines
Submission requirements for Innovations in Clinical Neuroscience (Online ISSN 2158-8341, Print ISSN 2158-8333) are in accordance with the International Committee of Medical Journal Editors (ICMJE).See Uniform Requirements for Manuscripts Submitted to Biomedical Journals. EDITORIAL PURPOSE … Read the original article. The post Author Guidelines appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 2, 2018 Category: Neuroscience Tags: Adverse Events in Psychiatry Brief Report Source Type: research

July-August 2018 Digital Edition
Click the cover below to access the July-August 2018 digital edition of Innovations in Clinical Neuroscience! The post July-August 2018 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

Editorial Message and Issue Highlights –Vol. 15, No. 7–8, July-August 2018
Dear Colleagues: Welcome to the July–August 2018 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a report by Brennan et al titled, “Implementation of the Electronic Columbia-Suicide Severity Rating Scale (eCSSRS) Across Four Phase IIIb Clinical Trials in HIV-infected Individuals (ARIA, STRIIVING, DAWNING and INSPIRING).” Here, researchers assessed site perspectives on implementation of the eC-SSRS, which was used in Phase IIIb studies of dolutegravir. Next, in a case report by Teo et al titled, “Atypical Neuroleptic Malignant Syndrome (NMS) Precipitated by Clozapine and Quetiapine Ove...
Source: Innovations in Clinical Neuroscience - July 1, 2018 Category: Neuroscience Authors: Chris Moccia Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Worsening Choreoathetosis in Huntington ’s Disease with Fluoxetine, Lisdexamfetamine, and Melatonin: A Case Report
Conclusion Our case is the second to describe worsened choreoathetoid movements with fluoxetine and psychostimulants in HD, and the first with melatonin. These observations are objectified by our patient’s marked improvements in movement and handwriting assessments (Figure 1).   We calculated Naranjo adverse event scores of 5, 5, and 2 for fluoxetine, lisdexamfetamine, and melatonin, respectively, based on several years of this individual’s outpatient medical records and current available literature (Table 1). Due to physiological and biochemical changes associated with HD progression, these medications could have...
Source: Innovations in Clinical Neuroscience - July 1, 2018 Category: Neuroscience Authors: Chris Moccia Tags: Case Report Current Issue Neurodegenerative Disease amphetamine antidepressant chorea dopamine Fluoxetine Huntington’s disease melatonin psychostimulant Source Type: research

Transition from Obsession to Delusion in Schizo-obsessive Disorder: A Case Report and Literature Overview
Conclusion We believe our diagnosis of schizo-obsessive disorder in the described patient is appropriate due to his symptoms of schizophrenia and OCD. The OCS at first seemed to have retarded the psychotic manifestation; however, the negative and cognitive symptoms of schizophrenia associated with OCS were prominent, and we believe this greatly contributed to the poor prognosis of our patient. The improvement of his OCS occurred with the emergence of an over-valued idea, corroborating the existence of a schizo-obsessive spectrum modulated by the presence and extent of phenomenological features related to insight. Therefore...
Source: Innovations in Clinical Neuroscience - July 1, 2018 Category: Neuroscience Authors: Chris Moccia Tags: Case Report Current Issue Neurodegenerative Disease Schizophrenia comorbidity insight obsessive compulsive disorder Source Type: research