Transition from Obsession to Delusion in Schizo-obsessive Disorder: A Case Report and Literature Overview

Conclusion We believe our diagnosis of schizo-obsessive disorder in the described patient is appropriate due to his symptoms of schizophrenia and OCD. The OCS at first seemed to have retarded the psychotic manifestation; however, the negative and cognitive symptoms of schizophrenia associated with OCS were prominent, and we believe this greatly contributed to the poor prognosis of our patient. The improvement of his OCS occurred with the emergence of an over-valued idea, corroborating the existence of a schizo-obsessive spectrum modulated by the presence and extent of phenomenological features related to insight. Therefore, although the transition of an obsessive into a psychotic symptom seems to be a rare event, it is possibly a sign of poor prognosis in the schizo-obsessive spectrum. Acknowledgments We are deeply indebted to the staff and colleagues from the Psychiatric Unit of the State University of Rio de Janeiro, in particular to Professor Max de Carvalho, for his helpful comments on the dissertation written by ESM and supervised by OLS. References Berrios GE. Obsessive-compulsive disorder: its conceptual history in France during the 19th century. Compr Psychiatry. 1989;30(4): 283–295 Schirmbeck F, Zink M. Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors. Front Pharmacol. 2013;4:99. Poyurovsky M, Koran LM. Obsessive–compulsive disorder (OCD) with schizotypy vs. schizophrenia with OCD: diagnostic dilemmas ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue Neurodegenerative Disease Schizophrenia comorbidity insight obsessive compulsive disorder Source Type: research