Editorial Message and Issue Highlights –Vol. 15, No. 7–8, July-August 2018
Dear Colleagues: Welcome to the July–August 2018 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a report by Brennan et al titled, “Implementation of the Electronic Columbia-Suicide Severity Rating Scale (eCSSRS) Across Four Phase IIIb Clinical Trials in HIV-infected Individuals (ARIA, STRIIVING, DAWNING and INSPIRING).” Here, researchers assessed site perspectives on implementation of the eC-SSRS, which was used in Phase IIIb studies of dolutegravir. Next, in a case report by Teo et al titled, “Atypical Neuroleptic Malignant Syndrome (NMS) Precipitated by Clozapine and Quetiapine Overdose: A Diagnostic Challenge,” the authors describe the case of a 43-year-old man with a history of treatment-resistant schizophrenia, diabetes mellitus, and hypertension who overdosed on his medications, including clozapine, quetiapine and venlafaxine. The patient met some but not all of the typical diagnostic criteria for NMS; however, his extremely high serum creatine kinase levels, among other factors, led to the diagnosis of an atypical form of NMS. The authors describe the patient’s treatment plan, discuss signs, symptoms, and causes of NMS, and review treatment options. Following this, Scotti-Muzzi and Saide present their case report titled, “Transition from Obsession to Delusion in Schizo-obsessive Disorder: A Case Report and Literature Overview.” Here, the authors describe the case of a young man who experien...
[This Day] Abuja -Over 5,000 persons have benefited from diabetes, hypertension, cervical and breast cancer free screening, which was facilitated by MITEDA Wellness Initiative, a nongovernmental organisation and in collaboration with the Lagos State government.
Case out of UK. Makes no sense. Media sensationalized. Woman in her 30s is left with PTSD after being able to FEEL her surgeon cutting her torso because blundering NHS staff kept her awake and operated on her with the wrong anaesthetic Woman in her 30s could FEEL surgeon cut her torso open in nightmare op Yeovil District Hospital (pictured) has accepted responsibility for the event and said a 'communication breakdown' led staff to use the wrong anaesthetic. The patient said medics couldn't hear her scream. ...
Authors: Robino C, Compagnone CA, Pozzi F, Curto F, Chieregato A PMID: 31820877 [PubMed - as supplied by publisher]
(Elsevier) High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs. A new study in The American Journal of Pathology, published by Elsevier, sheds light on the pathology underlying PAH and shows that dofetilide, an FDA-approved KV11.1 channel blocker for the treatment of cardiac arrhythmias (brand name: Tikosyn), may be used for treatment of PAH.
Conclusion: Specific OCD symptom subtypes may be associated with some psychological processes involved in sexual response. Sexual well-being should be carefully evaluated by practitioners and should be regarded as a treatment target. Future studies should investigate more comprehensively the processes involved in sexuality. PMID: 31819761 [PubMed]
Authors: Santos VA, Hoirisch-Clapauch S, Nardi AE, Freire RC Abstract Background: Acute administration of caffeine produces panic attacks in most Panic Disorder (PD) patients, but little is known about chronic caffeine use in these patients. Objective: To assess caffeine use in patients with PD and to ascertain if caffeine consumption is associated with sociodemographic or clinical features. Methods: 65 adults with PD and 66 healthy controls were included in the current study. Their caffeine intake within the previous week was quantified with a questionnaire and compared. Harmful caffeine use was defined as...
Conclusion: Our results confirm a significant relationship between AT and trauma-/stress-related symptoms, which seems to prevail on sex differences among high-risk subjects. PMID: 31819759 [PubMed]
Conclusion: Individuals in homologous MAR are a more distressed subgroup which requires a tailored supportive psychological intervention specifically on sexual and social concerns. PMID: 31819758 [PubMed]
Conclusion: Perceived Physical Health should be evaluated and addressed by clinicians during treatment, particularly with older, female and less severe patients. Lifestyle interventions might be implemented. PMID: 31819755 [PubMed]
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