Editorial Message and Issue Highlights –Vol. 15, No. 7–8, July-August 2018

Dear Colleagues: Welcome to the July–August 2018 issue of Innovations in Clinical Neuroscience (ICNS). We start this issue with a report by Brennan et al titled, “Implementation of the Electronic Columbia-Suicide Severity Rating Scale (eCSSRS) Across Four Phase IIIb Clinical Trials in HIV-infected Individuals (ARIA, STRIIVING, DAWNING and INSPIRING).” Here, researchers assessed site perspectives on implementation of the eC-SSRS, which was used in Phase IIIb studies of dolutegravir. Next, in a case report by Teo et al titled, “Atypical Neuroleptic Malignant Syndrome (NMS) Precipitated by Clozapine and Quetiapine Overdose: A Diagnostic Challenge,” the authors describe the case of a 43-year-old man with a history of treatment-resistant schizophrenia, diabetes mellitus, and hypertension who overdosed on his medications, including clozapine, quetiapine and venlafaxine. The patient met some but not all of the typical diagnostic criteria for NMS; however, his extremely high serum creatine kinase levels, among other factors, led to the diagnosis of an atypical form of NMS. The authors describe the patient’s treatment plan, discuss signs, symptoms, and causes of NMS, and review treatment options. Following this, Scotti-Muzzi and Saide present their case report titled, “Transition from Obsession to Delusion in Schizo-obsessive Disorder: A Case Report and Literature Overview.” Here, the authors describe the case of a young man who experienced intermittent symptoms of obs...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research