CNS Summit 2019 Abstracts of Poster Presentations
A message from the editor: Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that is being presented during CNS Summit 2019. The supplement is also available online by visiting […] (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - September 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Supplements Trial Methodology clinical trials CNS Summit Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 7–8, July-August 2019
Dear Colleagues: Welcome to the July–August 2019 edition of Innovations in Clinical Neuroscience (ICNS). We start this issue with a meta-analysis by Whitlock, Woodward, and Alexander titled, “Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.” Here, the authors investigated the accuracy of the popular theory that placebo […] The post Editorial Message and Issue Highlights–Vol. 16, No. 7–8, July-August 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Editorial Message Source Type: research

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies
by Mark E. Whitlock, PhD; Philip W. Woodward, MPhil; and Robert C. Alexander, MD Dr. Whitlock is BioStatistics Head of Internal Medicine, Early Clinical Development, for Pfizer in Cambridge, United Kingdom. Mr. Woodward is an independent statistics consultant in Newmarket, United Kingdom. Dr. Alexander is with Takeda Pharmaceuticals International Company in Cambridge, Massachusetts. Funding: No […] The post Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Meta-analysis antidepressant effects clinical trials orthogonal regression placebo additivity placebo response Source Type: research

High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure
by Megan K. Skelly, PharmD, BCPS; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Claudia Lee, MD Drs. Skelly, Demler, and Lee are with the State University at Buffalo (SUNY) School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice in Buffalo, New York and Drs. Demler and Lee are also with New York […] The post High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms Psychopharmacology clozapine seizure withdrawal Source Type: research

Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child
by Catherine Butz, PhD; Cindy Iske, MS, OTR/L; Natalie Truba, PhD; and Kristen Trott, PhD Drs. Butz, Truba, and Trott are with the Psychology Department, and Ms. Iske is Program Manager for the Rehabilitation Unit, Physical Medicine and Rehabilitation Service, at Nationwide Children’s Hospital in Columbus, Ohio. Funding: No funding was provided. Disclosures: The authors […] The post Treatment of Functional Gait Abnormality in a Rehabilitation Setting: Emphasizing the Physical Interventions for Treating the Whole Child appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Movement Disorders Original Research conversion mobility rehabilitation short-term Source Type: research

The Very Important Patient
by Danielle Gainer, MD, and Allison E. Cowan, MD Dr. Gainer is Assistant Professor, and Dr. Cowan is Associate Professor, in the Department of Psychiatry at Wright State University in Dayton, Ohio. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Department editors: Julie […] The post The Very Important Patient appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Practice Management Psychotherapy Rounds countertransference difficult patient entitled patient influential patient physician patient VIP patient Source Type: research

Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy
by Masaru Nakamura, MD, PhD, and Takahiko Nagamine, MD, PhD Dr. Nakamura is with the Department of Psychiatric Internal Medicine at Kosekai-Kusatsu Hospital in Hiroshima, Japan. Dr. Nagamine is with the Department of Psychiatric Internal Medicine at Sunlight Brain Research Center in Yamaguchi, Japan. Funding: No funding was provided. Disclosures: The authors have no conflicts […] The post Severe Lamotrigine-induced Hyponatremia Associated with Takotsubo Cardiomyopathy appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue Psychiatry Apical ballooning syndrome hyponatremia lamotrigine syndrome of inappropriate secretion of antidiuretic hormone takotsubo cardiomyopathy Source Type: research

Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer ’s Disease Stage
by Yue Deng, MSc; Brianna M. Marsh, BSc student; and Jackob Moskovitz, PhD Mr. Deng, Ms. Marsh, and Dr. Moskovitz are with the Department of Pharmacology and Toxicology at the School of Pharmacy, University of Kansas in Lawrence, Kansas. Funding: Support for the studies were provided by the KU ADC P30 AG035982 and the Landon […] The post Increased Levels of Protein-methionine Sulfoxide in Plasma Correlate with a Shift from a Mild Cognitive Impairment to an Alzheimer’s Disease Stage appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Alzheimer's Disease Cognition Current Issue Original Research Antioxidants blood-plasma methionine oxidation Source Type: research

Risk Management: Communicating with Family Members and Other Caregivers
by Charles D. Cash, JD, LLM Mr. Cash is Assistant Vice President at PRMS, Inc. in Arlington, Virginia. Funding: No funding was provided for the preparation of this article. Disclosures: The author is an employee of PRMS Inc., a risk management consulting company for healthcare providers. This ongoing column is dedicated to providing information to our […] The post Risk Management: Communicating with Family Members and Other Caregivers appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Risk Management caregivers communication Source Type: research

Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube
Dear Editor: Social media platforms are increasingly used to disseminate health promotion and patient education.1–5 Impressions click-through rate (CTR) is the number of clicks on a health promotion and/or patient education ad, divided by the times the ad was shown on a social media platform. A recent study explored the practicality of Facebook advertising to […] The post Letter to the Editor: The Click-through Rate as a Measure of Dementia Health Promotion on YouTube appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Dementia Letters to the Editor click-through rate youtube Source Type: research

ICNS July-August 2019 Digital Edition
Click the cover below to access the July-August 2019 digital edition of Innovations in Clinical Neuroscience! The post ICNS July-August 2019 Digital Edition appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - July 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Digital Editions Source Type: research

The Neuroscience Report —Vol. 54 (May 17, 2019): Migraines
Welcome to The Neuroscience Report, where we highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: Migraines 5 Journal Articles Understanding the nature of psychiatric comorbidity in migraine: a systematic […] The post The Neuroscience Report—Vol. 54 (May 17, 2019): Migraines appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 17, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: The Neuroscience Report migraines Source Type: research

Editorial Message and Issue Highlights –Vol. 16, No. 5–6, May-June 2019
Dear Colleagues: Welcome to the May-June 2019 edition of Innovations in Clinical Neuroscience (ICNS). In this issue, we revisit the topic of postpartum depression in men with a review article of the same name by Scarff. Here, the author describes the symptoms, risk factors, and treatment options for this disorder in men, and highlights the […] The post Editorial Message and Issue Highlights–Vol. 16, No. 5–6, May-June 2019 appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Editor's Message: Issue Highlights Source Type: research

Postpartum Depression in Men
by Jonathan R. Scarff, MD Dr. Scarff is a psychiatrist with the Behavioral Health Service Line at Kenner Army Health Clinic in Fort Lee, Virginia. Funding: No funding was provided. Disclosures: The authors have no conflicts of interest relevant to the content of this article. Abstract: Postpartum depression (PPD) is often defined as an episode […] The post Postpartum Depression in Men appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Depression Psychiatry Review antidepressant fathers postpartum psychotherapy Source Type: research

Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study
by Leslie Citrome, MD, MPH; Stephanie S. O’Malley, PhD; David McDonnell, MD; Ying Jiang, PhD; Adam C. Simmons, MPH; Mark P. Berry; and Lauren E. DiPetrillo, PhD Dr. Citrome is with the Department of Psychiatry and Behavioral Sciences at New York Medical College in Valhalla, New York. Dr. O’Malley is with the Department of Psychiatry […] The post Olanzapine Plus Samidorphan in Subjects with Schizophrenia and Comorbid Alcohol Use Disorder: Rationale and Design for a Phase II, Double-blind, Randomized Study appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - May 1, 2019 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Drug Development Schizophrenia Study Protocol alcohol use disorder ALKS 3831 olanzapine samidorphan Source Type: research