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Specialty: Endocrinology
Condition: Heart Disease

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Total 288 results found since Jan 2013.

Deep learning approach for diabetes prediction using PIMA Indian dataset
ConclusionThe outcome of the study confirms that DL provides the best results with the most promising extracted features. DL achieves the accuracy of 98.07% which can be used for further development of the automatic prognosis tool. The accuracy of the DL approach can further be enhanced by including the omics data for prediction of the onset of the disease.
Source: Journal of Diabetes and Metabolic Disorders - April 13, 2020 Category: Endocrinology Source Type: research

The association of thyroid stimulation hormone levels with incident ischemic heart disease, incident stroke, and all-cause mortality
ConclusionThe results do not provide evidence of a harmful effect of decreased or increased TSH on IHD or stroke in the general population. However, there is some indication of an elevated risk for all-cause mortality with TSH 2.5 –5 mU/l compared with 0.4–2.5 mU/l.
Source: Endocrine - February 9, 2020 Category: Endocrinology Source Type: research

Association Between Obesity Type and Common Vascular and Metabolic Diseases: A Cross-Sectional Study
Conclusions: Central obesity alone and compound obesity are associated with the risk of hypertension, hyperlipidemia, and diabetes mellitus. Compound obesity but not central obesity alone is associated with the risk of coronary heart disease, but further research is needed to confirm it. There are no significant relationship between stroke and central obesity alone or compound obesity.
Source: Frontiers in Endocrinology - January 8, 2020 Category: Endocrinology Source Type: research

Screening for non-alcoholic fatty liver disease using liver stiffness measurement and its association with chronic kidney disease and cardiovascular complications in patients with type 2 diabetes.
CONCLUSION: - These results suggest that NAFLD and significant LF (as assessed by FibroScan) are very commonly seen in T2DM outpatients with no known liver disease attending a secondary-care diabetes service, and that increased LF is associated with a greater proportion of chronic vascular complications, especially CKD. PMID: 31786361 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - November 27, 2019 Category: Endocrinology Authors: Mantovani A, Turino T, Lando MG, Gjini K, Byrne CD, Zusi C, Ravaioli F, Colecchia A, Maffeis C, Salvagno G, Lippi G, Bonora E, Targher G Tags: Diabetes Metab Source Type: research

Lowering Targeted Atherogenic Lipoprotein Cholesterol Goals for Patients at “Extreme” ASCVD Risk
AbstractPurpose of ReviewTo review randomized interventional clinical and imaging trials that support lower targeted atherogenic lipoprotein cholesterol goals in “extreme” and “very high” atherosclerotic cardiovascular disease (ASCVD) risk settings. Major atherosclerotic cardiovascular event (MACE) prevention among the highest risk patients with ASCVD requires aggressive management of global risks, including lowering of the fundamental atherogenic ap olipoprotein B-associated lipoprotein cholesterol particles [i.e., triglyceride-rich lipoprotein remnant cholesterol, low-density lipoprotein cholesterol (LDL-C), and ...
Source: Current Diabetes Reports - November 20, 2019 Category: Endocrinology Source Type: research

Prevalence of diabetic nephropathy among Chinese patients with type 2 diabetes mellitus and different categories of their estimated glomerular filtration rate based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation in primary care in Hong Kong: a cross-sectional study
ConclusionsDiabetic nephropathy was common among Chinese patients with type 2 diabetes in primary care in Hong Kong. Early identification and control of the modifiable risk factors are of upmost importance in preventing the complication.
Source: Journal of Diabetes and Metabolic Disorders - November 14, 2019 Category: Endocrinology Source Type: research

REVIEW: Obesity, neuroinflammation and reproductive function.
Abstract The increasing occurrence of obesity has become a significant public health concern. Obese individuals have higher prevalence of heart disease, stroke, osteoarthritis, diabetes, and reproductive disorders. Reproductive problems include menstrual irregularities, pregnancy complications, and infertility due to anovulation, in women, and lower testosterone and diminished sperm count, in men. In particular, obese women have reduced levels of both gonadotropin hormones and, in obese men, lower testosterone is accompanied by diminished luteinizing hormone. Together these findings indicate central dysregulation ...
Source: Endocrinology - September 11, 2019 Category: Endocrinology Authors: Lainez NM, Coss D Tags: Endocrinology Source Type: research

Comorbid depression and risk of cardiac events and cardiac mortality in people with diabetes: A systematic review and meta-analysis
To examine the association of comorbid occurrence of diabetes and depression with risk of cardiovascular endpoints including cardiovascular mortality, coronary heart disease and stroke.
Source: Diabetes Research and Clinical Practice - August 13, 2019 Category: Endocrinology Authors: A. Farooqi, K. Khunti, S. Abner, C. Gillies, R. Morriss, S. Seidu Source Type: research

Cancer has overtaken cardiovascular disease as the commonest cause of death in Scottish type  2 diabetes patients: A population‐based study (The Ayrshire Diabetes Follow‐up Cohort study)
ConclusionsThis study confirmed increased mortality risk in type  2 diabetes patients, and suggests that where cardiovascular risk factors are being treated aggressively, cancer takes on a greater importance in the cause of death. Should greater consideration now be given for cancer as a complication of diabetes?
Source: Journal of Diabetes Investigation - July 24, 2019 Category: Endocrinology Authors: Andrew Collier, Carron Meney, Mario Hair, Lyall Cameron, James G Boyle Tags: Original Article Source Type: research

Extreme Atherosclerotic Cardiovascular Disease (ASCVD) Risk Recognition
AbstractPurpose of ReviewTo distinguish extreme and very high atherosclerotic cardiovascular disease (ASCVD) event risk based on prospective epidemiological studies and clinical trial results.Recent FindingsClinical practice guidelines have categorized patients with either a history of one or more “clinical ASCVD” events or “coronary heart disease (CHD) risk equivalency” to be at “very high risk” for a recurrence or a first event, respectively. A 20% or greater 10-year ASCVD risk for a composite 3-point “major” atherosclerotic cardiovascular event (MACE) of non-fatal myocardia l infarction (MI), non-fatal s...
Source: Current Diabetes Reports - July 21, 2019 Category: Endocrinology Source Type: research

A case control study of clinical and biochemical parameters of metabolic syndrome with special attention among young and middle aged population
Conclusion: The risk factors like high TG, low HDL, high BP, and high fasting glucose were found higher particularly in younger population which may lead to diagnosis & complications of diabetes, hypertension and lipid abnormality. Due to changing physiology in young and middle age population these individuals are moving towards metabolic syndrome easily and needs frequent monitoring, preventive checkups, and lifestyle changes to prevent complications.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - July 14, 2019 Category: Endocrinology Source Type: research

The relationship between mean platelet volume and albuminuria in patients with type 2 diabetes mellitus
ConclusionsThe mean MPV was statistically significantly higher in the uncontrolled DM group and there was a statistically significant positive correlation between MPV and albuminuria.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - July 14, 2019 Category: Endocrinology Source Type: research

Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial
Publication date: Available online 1 July 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Kausik K Ray, Helen M Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L Bhatt, Vera A Bittner, Andrzej J Budaj, Rafael Diaz, Shaun G Goodman, Corinne Hanotin, Robert A Harrington, J Wouter Jukema, Virginie Loizeau, Renato D Lopes, Angèle Moryusef, Jan Murin, Robert Pordy, Arsen D Ristic, Matthew T Roe, José TuñónSummaryBackgroundAfter acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1·4–1·8 mmol/L with ezetimibe or statins reduces...
Source: The Lancet Diabetes and Endocrinology - July 2, 2019 Category: Endocrinology Source Type: research

Cancer has overtaken cardiovascular disease as the commonest cause of death in Scottish type 2 diabetes: a population based study (The Ayrshire Diabetes fOllow ‐up Cohort study)
ConclusionsThis study confirmed increased mortality risk in type 2 diabetes and suggests that where cardiovascular risk factors are being treated aggressively, cancer takes on a greater importance in the cause of death. Should greater consideration now be given for cancer as a complication of diabetes?This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - July 1, 2019 Category: Endocrinology Authors: Andrew Collier, Carron Meney, Mario Hair, Lyall Cameron, James G Boyle Tags: Original Article Source Type: research