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Specialty: Endocrinology
Condition: Heart Disease

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Total 288 results found since Jan 2013.

Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases.
Abstract As nutrition-related chronic diseases have become more and more frequent, the importance of dietary prevention has also increased. Dietary fat plays a major role in human nutrition, and modification of fat and/or fatty acid intake could have a preventive potential. The aim of the guideline of the German Nutrition Society (DGE) was to systematically evaluate the evidence for the prevention of the widespread diseases obesity, type 2 diabetes mellitus, dyslipoproteinaemia, hypertension, metabolic syndrome, coronary heart disease (CHD), stroke, and cancer through the intake of fat or fatty acids. The main res...
Source: Diabetes Metab - October 1, 2015 Category: Endocrinology Authors: Wolfram G, Bechthold A, Boeing H, Ellinger S, Hauner H, Kroke A, Leschik-Bonnet E, Linseisen J, Lorkowski S, Schulze M, Stehle P, Dinter J Tags: Ann Nutr Metab Source Type: research

Evaluating the impact of type 2 diabetes mellitus on cardiovascular risk in persons with metabolic syndrome using the UKPDS risk engine.
CONCLUSION: MS was more common in subjects with T2DM compared with controls (irrespective of the diagnostic criteria used) and MS appears to increase the risk of a coronary event in subjects with T2DM by threefold. Also from this study, MS did not appear to cause an additional increase in the risk of stroke in subjects with T2DM. PMID: 26396537 [PubMed]
Source: Diabetes Metab - September 26, 2015 Category: Endocrinology Authors: Ogedengbe OS, Ezeani IU, Chukwuonye II, Anyabolu EN, Ozor II, Eregie A Tags: Diabetes Metab Syndr Obes Source Type: research

Social Determinants of Health in Adults with Type 2 Diabetes–Contribution of Mutable and Immutable Factors
Type 2 diabetes affects more than 29 million people in the US, with an estimated 8.1 million individuals having undiagnosed type 2 diabetes and an estimated 86 million Americans diagnosed with prediabetes [1]. In 2012, costs associated with type 2 diabetes totaled $245 billion, including direct and indirect costs [1]. The remarkable cost of type 2 diabetes can be attributed to various complications and comorbid conditions associated with this chronic illness, including hypo- and hyperglycemia, high blood pressure, high LDL cholesterol, heart disease, stroke, blindness, kidney disease, and amputations [1].
Source: Diabetes Research and Clinical Practice - September 17, 2015 Category: Endocrinology Authors: Rebekah J. Walker, Brittany L. Smalls, Leonard E. Egede Source Type: research

Social determinants of health in adults with type 2 diabetes—Contribution of mutable and immutable factors
Type 2 diabetes affects more than 29 million people in the US, with an estimated 8.1 million individuals having undiagnosed type 2 diabetes and an estimated 86 million Americans diagnosed with prediabetes [1]. In 2012, costs associated with type 2 diabetes totaled $245 billion, including direct and indirect costs [1]. The remarkable cost of type 2 diabetes can be attributed to various complications and comorbid conditions associated with this chronic illness, including hypo- and hyperglycemia, high blood pressure, high LDL cholesterol, heart disease, stroke, blindness, kidney disease, and amputations [1].
Source: Diabetes Research and Clinical Practice - September 17, 2015 Category: Endocrinology Authors: Rebekah J. Walker, Brittany L. Smalls, Leonard E. Egede Source Type: research

Evaluating the impact of type 2 diabetes mellitus on cardiovascular risk in persons with metabolic syndrome using the UKPDS risk engine
Conclusion: MS was more common in subjects with T2DM compared with controls (irrespective of the diagnostic criteria used) and MS appears to increase the risk of a coronary event in subjects with T2DM by threefold. Also from this study, MS did not appear to cause an additional increase in the risk of stroke in subjects with T2DM.Keywords: diabetes mellitus, metabolic syndrome, coronary heart disease, cardiovascular disease, UKPDS risk engine
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - September 15, 2015 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Sex-Specific Differential in Risk of Diabetes-Related Macrovascular Outcomes
In conclusion, diabetes is associated with a slightly higher risk of cardiovascular disease in women compared to men. Future studies should further explore the reasons underlying imperfect use of medications that lower cardiovascular risk in both women and men with diabetes.
Source: Current Diabetes Reports - September 14, 2015 Category: Endocrinology Source Type: research

Impact of Socioeconomic Status on Cardiovascular Disease and Mortality in 24,947 Individuals With Type 1 Diabetes
CONCLUSIONS Low SES increases the risk of CVD and death by a factor of 2–3 in type 1 diabetes.
Source: Diabetes Care - July 23, 2015 Category: Endocrinology Authors: Rawshani, A.; Svensson, A.-M.; Rosengren, A.; Eliasson, B.; Gudbjornsdottir, S. Tags: Cardiovascular and Metabolic Risk Source Type: research

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey).
Conclusions. We confirmed the association of known variants within the 9p21 interval with T2D and CHD. Our results further suggest that additional CHD susceptibility variants exist in this region. PMID: 26089876 [PubMed]
Source: International Journal of Endocrinology - June 21, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Potential peptides in atherosclerosis therapy.
Authors: Marleau S, Mellal K, Huynh DN, Ong H Abstract Atherosclerosis is the main underlying cause of ischemic heart disease and related acute cardiovascular complications, including myocardial infarction and stroke. In view of the failure of statins to demonstrate a beneficial effect in all patients, exhaustive research efforts have unfold into different research avenues, in close relation to the increase in basic knowledge regarding lipoprotein metabolism, macrophage function and inflammatory conditions associated with atherosclerosis. This review focuses specifically on potential therapeutic peptides targeting ...
Source: Frontiers of Hormone Research - June 4, 2015 Category: Endocrinology Tags: Front Horm Res Source Type: research

Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data
Publication date: Available online 28 May 2015 Source:The Lancet Diabetes & Endocrinology Author(s): Kunihiro Matsushita , Josef Coresh , Yingying Sang , John Chalmers , Caroline Fox , Eliseo Guallar , Tazeen Jafar , Simerjot K Jassal , Gijs W D Landman , Paul Muntner , Paul Roderick , Toshimi Sairenchi , Ben Schöttker , Anoop Shankar , Michael Shlipak , Marcello Tonelli , Jonathan Townend , Arjan van Zuilen , Kazumasa Yamagishi , Kentaro Yamashita , Ron Gansevoort , Mark Sarnak , David G Warnock , Mark Woodward , Johan Ärnlöv Background The usefulness of estimated glomerular filtration rate (eGFR) and albumin...
Source: The Lancet Diabetes and Endocrinology - May 30, 2015 Category: Endocrinology Source Type: research

Early specialist care for diabetes: who benefits most? A propensity score‐matched cohort study
ConclusionsEarly endocrinologist care is associated with a lower incidence of cardiovascular events and death among newly diagnosed patients with diabetes who have comorbid medical conditions.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - May 16, 2015 Category: Endocrinology Authors: G. L. Booth, B. R. Shah, P. C. Austin, J. E. Hux, J. Luo, C. E. Lok Tags: Research Article Source Type: research

Prevalence of type 2 diabetes–associated complications in Pakistan
This study indicates high prevalence of macro-vascular complications along with high triglyceride level and hypertension among T2DM patients. A study with larger sample set is suggested to explore the relation of genetic and environmental factors on disease progression and sub-population variations.
Source: International Journal of Diabetes in Developing Countries - April 17, 2015 Category: Endocrinology Source Type: research

Infertility etiologies are genetically and clinically linked with other diseases in single meta-diseases
The present review aims to ascertain whether different infertility etiologies share particular genes and/or molecular pathways with other pathologies and are associated with distinct and particular risks of later-life morbidity and mortality. In order to reach this aim, we use two different sources of information: (1) a public web server named DiseaseConnect (http://disease-connect.org) focused on the analysis of common genes and molecular mechanisms shared by diseases by integrating comprehensive omics and literature data; and (2) a literature search directed to find clinical comorbid relationships of infertility etiologi...
Source: Reproductive Biology and Endocrinology - April 15, 2015 Category: Endocrinology Authors: Juan TarínMiguel García-PérezToshio HamataniAntonio Cano Source Type: research

Emerging cardiovascular indications of mineralocorticoid receptor antagonists
Publication date: April 2015 Source:Trends in Endocrinology & Metabolism, Volume 26, Issue 4 Author(s): Yasir Parviz , Javaid Iqbal , Bertram Pitt , David Adlam , Abdallah Al-Mohammad , Faiez Zannad Mineralocorticoid receptor (MR) antagonism is a well-established treatment modality for patients with hypertension, heart failure, and left ventricular systolic dysfunction (LVSD) post-myocardial infarction (MI). There are emerging data showing potential benefits of MR antagonists in other cardiovascular conditions. Studies have shown association between MR activation and the development of myocardial fibrosis, corona...
Source: Trends in Endocrinology and Metabolism - March 31, 2015 Category: Endocrinology Source Type: research

A novel risk score to predict cardiovascular disease risk in national populations (Globorisk): a pooled analysis of prospective cohorts and health examination surveys
Publication date: Available online 26 March 2015 Source:The Lancet Diabetes & Endocrinology Author(s): Kaveh Hajifathalian , Peter Ueda , Yuan Lu , Mark Woodward , Alireza Ahmadvand , Carlos A Aguilar-Salinas , Fereidoun Azizi , Renata Cifkova , Mariachiara Di Cesare , Louise Eriksen , Farshad Farzadfar , Nayu Ikeda , Davood Khalili , Young-Ho Khang , Vera Lanska , Luz León-Muñoz , Dianna Magliano , Kelias P Msyamboza , Kyungwon Oh , Fernando Rodríguez-Artalejo , Rosalba Rojas-Martinez , Jonathan E Shaw , Gretchen A Stevens , Janne Tolstrup , Bin Zhou , Joshua A Salomon , Majid Ezzati , Goodarz Danaei Backgrou...
Source: The Lancet Diabetes and Endocrinology - March 27, 2015 Category: Endocrinology Source Type: research