Filtered By:
Specialty: Endocrinology
Condition: Heart Disease

This page shows you your search results in order of date. This is page number 12.

Order by Relevance | Date

Total 288 results found since Jan 2013.

Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes
Conclusions/interpretationThere remains uncertainty about whether metformin reduces risk of cardiovascular disease among patients with type 2 diabetes, for whom it is the recommended first-line drug. Although this is mainly due to absence of evidence, it is unlikely that a definitive placebo-controlled cardiovascular endpoint trial among people with diabetes will be forthcoming. Alternative approaches to reduce the uncertainty include the use of electronic health records in long-term pragmatic evaluations, inclusion of metformin in factorial trials, publication of cardiovascular outcome data from adverse event reporting in...
Source: Diabetologia - August 2, 2017 Category: Endocrinology Source Type: research

Glycaemic control and the risk of hospitalisation for infection in patients with type 2 diabetes: Hong Kong Diabetes Registry
ConclusionsBurden of serious infection is high in diabetic population and a U‐shape relationship between glycaemia and infection‐related hospitalisation was detected in patients with type 2 diabetes.
Source: Diabetes/Metabolism Research and Reviews - July 21, 2017 Category: Endocrinology Authors: Andrea O.Y. Luk, Eric S.H. Lau, Kitty K.T. Cheung, Alice P. Kong, Ronald C.W. Ma, Risa Ozaki, Francis C.C. Chow, Wing ‐Yee So, Juliana C.N. Chan Tags: RESEARCH ARTICLE Source Type: research

Relationship between limited joint mobility of hand and carotid atherosclerosis in patients with type 2 diabetes
Cardiovascular disease (CVD) is the most prevalent cause of morbidity and mortality in patients with diabetes [1] and atherosclerosis is a major risk factor for CVD [2]. Type 2 diabetes is known risk for atherosclerosis, leading to non-embolic ischemic stroke [3] and peripheral arterial disease (PAD) [4]. To assess the risk for chronic heart disease (CHD) and CVD, traditional risk scores, such as Framingham Risk Score (FRS) and Framingham based risk score, have been widely used, however a previous report indicated that 175 of 1015 patients who classified low risk of FRS had subclinical atherosclerosis [5].
Source: Diabetes Research and Clinical Practice - July 20, 2017 Category: Endocrinology Authors: Yusuke Mineoka, Michiyo Ishii, Yoshitaka Hashimoto, Muhei Tanaka, Naoto Nakamura, Yasukazu Katsumi, Motohide Isono, Michiaki Fukui Source Type: research

Annual direct medical costs associated with diabetes ‐related complications in the event year and in subsequent years in Hong Kong
ConclusionsWide variations in direct medical cost in event year and subsequent years across different major complications were observed. Input of these data would be essential for economic evaluations of diabetes management programmes.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - June 21, 2017 Category: Endocrinology Authors: F. Jiao, C. K. H. Wong, S. C. W. Tang, C. S. C. Fung, K. C. B. Tan, S. McGhee, R. Gangwani, C. L. K. Lam Tags: Research Article Source Type: research

Usability and Clinical Efficacy of Diabetes Mobile Applications for Adults with Type 2 Diabetes: A Systematic Review
Type 2 diabetes (T2D) affects 382 million patients worldwide. This number is expected to increase by 35% globally in the coming years [1]. Poor glycemic control leads to complications, such as coronary heart disease or stroke (36.6%) [2]; visual impairment (19.1%) [3]; death related to hyperglycemic crisis (12.3% rate per 100,000 diabetic population) [4]; and limb amputation (3.3% rate per 1,000 diabetic population) [5]. Mobile health applications (apps) delivered through smartphones or tablets have the potential to help patients manage their diabetes.
Source: Diabetes Research and Clinical Practice - June 20, 2017 Category: Endocrinology Authors: Helen Fu, Siobhan K. McMahon, Cynthia R. Gross, Terrence J. Adam, Jean F. Wyman Source Type: research

Lower Extremity Peripheral Arterial Disease Is an Independent Predictor of Coronary Heart Disease and Stroke Risks in Patients with Type 2 Diabetes Mellitus in China.
In conclusion, lower extremity PAD increased coronary heart disease and stroke risks in T2DM. PMID: 28607554 [PubMed - in process]
Source: International Journal of Endocrinology - June 14, 2017 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Impact of glucose-lowering therapies on risk of stroke in type 2 diabetes.
Abstract Patients with type 2 diabetes (T2D) have an increased risk of stroke compared with people without diabetes. However, the effects of glucose-lowering drugs on risk of ischaemic stroke in T2D have been less extensively investigated than in coronary heart disease. Some evidence, including the UKPDS, has suggested a reduced risk of stroke with metformin, although the number of studies is limited. Inhibition of the KATP channels increases ischaemic brain lesions in animals. This is in agreement with a recent meta-analysis showing an increased risk of stroke with sulphonylureas vs. various comparators as both m...
Source: Diabetes and Metabolism - May 15, 2017 Category: Endocrinology Authors: Bonnet F, Scheen AJ Tags: Diabetes Metab Source Type: research

Prevalence of hypertension and prehypertension in adolescence in Ahvaz, Iran
Conclusions The prevalence of high blood pressure was found to be lower than other studies in our country. The prevalence of the high blood pressure in boys was significantly higher than girls. This study, like other studies showed high correlation between being overweight and an increase in systolic and diastolic blood pressure.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 10, 2017 Category: Endocrinology Source Type: research

Season of birth and the risk of type 2 diabetes in adulthood: a prospective cohort study of 0.5 million Chinese adults
Conclusions/interpretationIn this large prospective study, participants born in summer had a lower risk of adult type 2 diabetes compared with other seasons of birth, suggesting exposures in early life with some degree of seasonal variation might influence the risk of adult diabetes.
Source: Diabetologia - April 1, 2017 Category: Endocrinology Source Type: research

Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
CONCLUSIONS Adults with both high TG and low HDL-C, particularly those with diabetes, have increased risks of incident CHD and stroke. In particular, those with an LDL-C level ≥130 mg/dL may have an increased risk of incident stroke.
Source: Diabetes Care - March 20, 2017 Category: Endocrinology Authors: Lee, J. S.; Chang, P.-Y.; Zhang, Y.; Kizer, J. R.; Best, L. G.; Howard, B. V. Tags: Epidemiology/Health Services Research Source Type: research

Dietary factors associated with substantial proportion of deaths from cardiometabolic disease
Nearly half of all deaths due to heart disease, stroke and type 2 diabetes in the US in 2012 were associated with suboptimal consumption of certain dietary factors, according to a study published inJAMA.Medical Xpress
Source: Society for Endocrinology - March 8, 2017 Category: Endocrinology Source Type: news

Outcomes in patients with diabetes 10  years after liver transplantation
ConclusionsIn the present study diabetes was associated with a higher risk of liver graft rejection and cardiovascular events. There was also a trend for higher mortality, although the effect was not statistically significant. These findings suggest that patients with diabetes require a more rigorous pretransplant evaluation and closer monitoring after transplantation in order to try to reduce associated complications.
Source: Journal of Diabetes - February 27, 2017 Category: Endocrinology Authors: Agust ín Ramos‐Prol, David Hervás‐Marín, Alia García‐Castell, Juan F. Merino‐Torres Tags: Original Article Source Type: research

HbA1c in relation to incident diabetes and diabetes-related complications in non-diabetic adults at baseline
We compared the utility of glycated haemoglobin (HbA1c) and oral glucose tolerance (oGTT) in non-diabetic patients for identifying incident diabetes; all-cause mortality; cardiovascular disease (CVD) mortality; CVD, coronary heart disease (CHD), and ischaemic stroke events; and diabetes microvascular complications.Methods: Data from a New Zealand community setting were prospectively linked to hospitalization, mortality, pharmaceutical and laboratory test results data. After applying exclusion criteria (prior laboratory diagnosis or history of drug treatment for diabetes or hospitalisation for diabetes or CVD event), there ...
Source: Journal of Diabetes and Its Complications - February 19, 2017 Category: Endocrinology Authors: PA. Metcalf, C. Kyle, T. Kenealy, S. Wells, RT. Jackson Source Type: research

Influence of vitamin D levels on the treatment of premature ventricular complexes in patients with chronic kidney disease
Conclusions We suggest that the effectiveness of β-blocker treatment for PVCs in CKD patients was observed in all 25(OH)D levels. However, the responsiveness was higher in patients with a normal range of 25(OH)D in comparison to patients with deficiency or insufficiency in 25(OH)D levels. Whether vitamin D supplementation increases the efficacy of beta-blocker mediated suppression of PVCs requires further evaluation.
Source: IJC Metabolic and Endocrine - January 6, 2017 Category: Endocrinology Source Type: research

Gender Differences in Risks of Coronary Heart Disease and Stroke in Patients with Type 2 Diabetes Mellitus and Their Association with Metabolic Syndrome in China.
In conclusion, our findings indicated that Chinese women with T2DM are less susceptible to CHD and stroke than men. Further, MS increases the risk of both these events, highlighting the need for comprehensive metabolic control in T2DM. PMID: 28042294 [PubMed]
Source: International Journal of Endocrinology - January 4, 2017 Category: Endocrinology Tags: Int J Endocrinol Source Type: research