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Specialty: Neurology
Condition: Encephalitis

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Total 277 results found since Jan 2013.

Are We Aware of the Neurological Manifestations of Cytomegalovirus Infection in Immunocompetent Individuals?
Conclusion: CMV infection should be considered in the differential diagnosis of patients presenting with neurological symptoms, even among immunocompetent individuals, because of the high possibility that patients can greatly benefit from antiviral treatment at the early stage.
Source: The Neurologist - November 1, 2022 Category: Neurology Tags: Original Articles Source Type: research

COVID-19 Continuous-EEG Case Series: A Descriptive Study
Conclusions: In this observational case series of 16 patients with COVID-19 who were monitored with continuous video-EEG, most patients experienced a nonspecific encephalopathy. Clinical seizures and electrographic status epilepticus were the second most commonly observed neurological problem.
Source: Journal of Clinical Neurophysiology - November 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Stroke-like presentation of autoimmune chorea with positive anti-Yo and anti-MOG antibodies: a case report
AbstractWith the in-depth study of autoimmune encephalitis, more and more antibody combinations and clinical manifestations appear in our sights, enriching the spectrum of autoimmune encephalitis. Here, we report a case of a 58-year-old male patient with sudden involuntary movement of the left limb. The brain MRI was normal. CSF analysis showed slightly elevated protein (548.38  mg/L) and normal cell count(1.00 10^6/L). No tumors were detected by the whole-body PET-CT. Positive anti-Yo and anti-MOG antibodies were found in the blood. So we considered the diagnosis of autoimmune chorea with positive anti-Yo and anti-MOG a...
Source: Neurological Sciences - October 25, 2022 Category: Neurology Source Type: research

Bilateral ballism as limb-shaking transient ischemic attacks treated with unilateral carotid artery stent placement
A man in his 80s with no medical history and a heavy smoking habit experienced a sudden involuntary movement of the bilateral limbs, trunk, and tongue. He had mild dysarthria, and could not eat (Video 1). Symptoms lasted for several hours and days, with frequent onset during the day. No consciousness impairments, paralysis, or sensory disturbances were observed. Physical examination and laboratory data did not indicate meningitis, encephalitis, post-infectious causes, or autoimmune disorders.The electroencephalogram showed no abnormalities.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2022 Category: Neurology Authors: Toshihiko Shimizu, Keiko Haro, Masahiko Tagawa, Masaaki Hirata, Sachiko Iwano, Hiroshi Kosaka, Yuji Yamamoto Tags: Case Report Source Type: research

Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19
Curr Alzheimer Res. 2022 Sep 8. doi: 10.2174/1567205019666220908084559. Online ahead of print.ABSTRACTThe COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), a respiratory pathogen with neuroinvasive potential. Neurological COVID-19 manifestations include loss of smell and taste, headache, dizziness, stroke, and potentially fatal encephalitis. Several studies found elevated proinflammatory cytokines such as TNF-α, IFN-γ, IL-6 IL-8, IL-10 IL-16, IL-17A, and IL-18 in severely and critically ill COVID-19 patients, which may persist even after apparent recovery from infection. Bioma...
Source: Current Alzheimer Research - September 12, 2022 Category: Neurology Authors: Christos Tsagkaris Muhammad Bilal Irem Aktar Youssef Aboufandi Ahmet Tas Abdullahi Tunde Aborode Tarun Kumar Suvvari Shoaib Ahmad Anastasiia Shkodina Rachana Phadke Marwa S Emhamed Atif Amin Baig Athanasios Alexiou Ghulam Md Ashraf Mohammad Amjad Kamal Source Type: research

Case report: Acute vestibular syndrome and cerebellitis in anti-Yo paraneoplastic syndrome
We report three patients evaluated over the past decade with an acute AVS along with subtle downbeat nystagmus (DBN), followed by dysarthria and progressive truncal and limb ataxia, as well as increasing DBN intensity.MethodsAll patients underwent neurologic examination, video-oculography, MRI, serum cancer markers, spinal fluid examination, paraneoplastic panel testing, and oncologic workup. With a consolidated diagnosis of cancer/paraneoplastic syndrome, we treated with plasma exchange (PLEX), high-dose steroids, surgery, and oncologic investigation. We additionally provided oncotherapy in one out of three patients.Resul...
Source: Frontiers in Neurology - August 26, 2022 Category: Neurology Source Type: research

Late-onset seizures and epilepsy: Electroclinical features suggestive of autoimmune etiology
ConclusionOur study shows that high-frequency focal seizures with autonomic manifestations should raise the suspicion of AE in the elderly with new-onset seizures. It also highlights the relevant contribution of AEEG, which might reduce the diagnostic delay and provide useful clues to recognize AE.
Source: Frontiers in Neurology - August 12, 2022 Category: Neurology Source Type: research

Arterial Spin Labeling Imaging Characteristics of Anti-leucine-rich Glioma-Inactivated 1 Encephalitis: A Qualitative and Quantitative Analysis
DiscussionIn this preliminary study of six patients, we demonstrate an ASL hyperperfusion pattern, with a possible predilection for the right mesial temporal lobe on both qualitative and quantitative assessments in patients with seropositive LGI1. Larger scale studies are necessary to further characterize the strength of these associations.
Source: Frontiers in Neurology - July 28, 2022 Category: Neurology Source Type: research

Therapeutic Approaches to the Neurologic Manifestations of COVID-19
AbstractAs of May 2022, there have been more than 527 million infections with severe acute respiratory disease coronavirus type 2 (SARS-CoV-2) and over 6.2 million deaths from Coronavirus Disease 2019 (COVID-19) worldwide. COVID-19 is a multisystem illness with important neurologic consequences that impact long-term morbidity and mortality. In the acutely ill, the neurologic manifestations of COVID-19 can include distressing but relatively benign symptoms such as headache, myalgias, and anosmia; however, entities such as encephalopathy, stroke, seizures, encephalitis, and Guillain –Barre Syndrome can cause neurologic inj...
Source: Neurotherapeutics - July 21, 2022 Category: Neurology Source Type: research

Drug-resistant epilepsy at the age extremes: Disentangling the underlying etiology
Epilepsy Behav. 2022 May 25;132:108739. doi: 10.1016/j.yebeh.2022.108739. Online ahead of print.ABSTRACTThe incidence of epilepsy is highest at the extreme age ranges: childhood and elderly age. The most common syndromes in these demographics - self-limited epilepsies of childhood and idiopathic generalized epilepsies in pediatric age, focal epilepsy with structural etiology in older people - are expected to be drug responsive. In this work, we focus on such epilepsy types, overviewing the complex clinical background of unexpected drug-resistance. For self-limited epilepsies of childhood and idiopathic generalized epilepsi...
Source: Epilepsy and Behaviour - May 31, 2022 Category: Neurology Authors: Emanuele Bartolini Anna Rita Ferrari Simona Lattanzi Silvia Pradella Gaetano Zaccara Source Type: research

Recent Synergy of Nanodiamonds: Role in Brain-Targeted Drug Delivery for the Management of Neurological Disorders
AbstractThe aim of the present review article is to summarize the role of nanodiamonds in various neurological diseases. We have taken related literature of making this review article from ScienceDirect, springer, Research gate, PubMed, Sci-finder, etc. The current approaches for treating neurological conditions such as glioblastoma includes chemotherapy or combination anti-retro viral therapy for HIV (human immunodeficiency virus) or use of anti-Alzheimer drugs during cognitive impairment. These approaches can provide only symptomatic relief as they do not target the cause of the disease due to their inability to penetrat...
Source: Molecular Neurobiology - May 27, 2022 Category: Neurology Source Type: research

The spectrum of Neuro-COVID: A study of a comprehensively investigated large cohort from India
Conclusion: Stroke and encephalopathy constitute the most common neurological manifestations. The absence of preceding COVID-19 symptoms in nearly half the cases is striking. Poor outcome was seen in nearly 50% despite early recognition and management.
Source: Annals of Indian Academy of Neurology - May 25, 2022 Category: Neurology Authors: Seena Vengalil Rohan Mahale N Chakradhar Swathi Alluri PR Sagar Navanith VH Ganaraja KR Haripriya Holla Venkappayya Vikram Ajay Asranna Pooja Mailankody Doniparthi V Seshagiri H Manoj Cheerla VN Maturu CR Vaddepally Raghavendra Kenchaiah PR Srijithesh Jay Source Type: research