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Specialty: Neurology
Condition: Encephalitis

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Total 277 results found since Jan 2013.

HSV-2 encephalitis presenting as multifocal ischemic stroke
Source: Neurological Sciences - August 31, 2017 Category: Neurology Source Type: research

Parvovirus B19 infection associated with hemolytic anemia and cranial polyneuropathy
AbstractParvovirus B19 (PB19) is a common, widespread, small, single-stranded DNA virus which has been linked with a broad spectrum of clinical illnesses, including a variety of neurological complications such as encephalitis, meningitis, myelitis, stroke, cerebellar ataxia, and neuropathy. The authors describe a case of PB19 infection associated with hemolytic anemia and cranial polyneuropathy involving the second and third cranial nerves in a 23-year-old immunocompetent woman. The diagnosis of acute PB19 infection was established with detection of positive DNA and anti-PB19 IgM antibodies in blood samples. Antigangliosid...
Source: Journal of NeuroVirology - August 22, 2017 Category: Neurology Source Type: research

Prevention of epilepsy: Should we be avoiding clinical trials?
Abstract Epilepsy prevention is one of the great unmet needs in epilepsy. Approximately 15% of all epilepsy is caused by an acute acquired CNS insult such as traumatic brain injury (TBI), stroke or encephalitis. There is a latent period between the insult and epilepsy onset that presents an opportunity to intervene with preventive treatment that is unique in neurology. Yet no phase 3 epilepsy prevention studies, and only 2 phase 2 studies have been initiated in the last 16years. Current prevailing opinion is that the research community is not ready for clinical preventive epilepsy studies, and that animal models s...
Source: Epilepsy and Behaviour - June 21, 2017 Category: Neurology Authors: Klein P, Tyrlikova I Tags: Epilepsy Behav Source Type: research

Dacrystic seizures--a cry for help
A 69-year-old man with a history of myocardial infarction presented with crying-like spells. MRI demonstrated abnormal signal in the left mesiotemporal lobe, and he was diagnosed with stroke. Over the following 1 year, he developed progressive cognitive decline, slow gait, masked facies, hypophonic voice, and brief facial and upper extremity spasms (8 per hour) often followed by brief crying spells lacking emotion. Spell semiology was consistent with faciobrachial dystonic seizures1 and dacrystic seizures2 (video at Neurology.org/nn). Leucine-rich glioma-inactivated-1 (LGI1) autoantibodies, detected in serum, led to a diag...
Source: Neurology Neuroimmunology and Neuroinflammation - June 16, 2017 Category: Neurology Authors: Gadoth, A., Singh, J., Britton, J. W., Flanagan, E. P., Pittock, S. J. Tags: All Epilepsy/Seizures Clinical/Scientific Notes Source Type: research

Dacrystic seizures: A cry for help
A 69-year-old man with a history of myocardial infarction presented with crying-like spells. MRI demonstrated abnormal signal in the left mesiotemporal lobe, and he was diagnosed with stroke. Over the following 1 year, he developed progressive cognitive decline, slow gait, masked facies, hypophonic voice, and brief facial and upper extremity spasms (8 per hour) often followed by brief crying spells lacking emotion. Spell semiology was consistent with faciobrachial dystonic seizures1 and dacrystic seizures2 (video at Neurology.org/nn). Leucine-rich glioma-inactivated-1 (LGI1) autoantibodies, detected in serum, led to a diag...
Source: Neurology Neuroimmunology and Neuroinflammation - June 16, 2017 Category: Neurology Authors: Gadoth, A., Singh, J., Britton, J. W., Flanagan, E. P., Pittock, S. J. Tags: All Epilepsy/Seizures Clinical/Scientific Notes Source Type: research

Burden of herpes simplex virus encephalitis in the United States
AbstractHerpes simplex virus encephalitis (HSVE) is a disease of public health concern, but its burden on the healthcare of United States has not been adequately assessed recently. We aimed to define the incidence, complications and outcomes of HSVE in the recent decade by analyzing data from a nationally representative database. Healthcare Cost and Utilization Project databases were utilized to identify patients with primary discharge diagnosis of HSVE. Annual hospitalization rate was estimated and several preselected inpatient complications were identified. Regression analyses were used to identify mortality predictors. ...
Source: Journal of Neurology - May 17, 2017 Category: Neurology Source Type: research

An Unusual Presentation of Varicella Zoster Virus with Acute Cerebellitis and SIADH without a rash. (P2.315)
Conclusions:This report illustrates an unusual presentation of acute VZV cerebellitis and encephalitis, without a rash. To our understanding, this shows for the first time, severe acute onset neurological sequelae due to VZV.Disclosure: Dr. Lubomski has nothing to disclose. Dr. Markus has nothing to disclose. Dr. Brown has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lubomski, M., Markus, R., Brown, L. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research

Misdiagnosis of CADASIL: A single Medical Center experience (P1.251)
Conclusions:CADASIL is the most prevalent monogenic cerebral small-vessel arteriopathy. Despite wide availability of genetic testing, misdiagnosis and delay diagnosis are common. We encourage for enhanced awareness of CADASIL among patients with migraines with aura, recurrent TIAs or subcortical ischemic strokes, and mood disorder, in order to provide appropriate multidisciplinary treatment, psychological support and genetic counselingStudy Supported by: n/aDisclosure: Dr. Ortiz-Garcia has nothing to disclose. Dr. Orjuela has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Biller has received personal compensat...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ortiz-Garcia, J., Orjuela, K., Sweis, R., Biller, J. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Rapidly Progressive atypical Posterior Reversible Encephalopathy Syndrome (PRES) associated with B-cell lymphoma (P4.065)
Conclusions:This case illustrates a rapidly progressive clinicoradiological syndrome with remarkable radiographical features of atypical PRS, and association with diffuse B-cell lymphomaDisclosure: Dr. Bronstein has nothing to disclose. Dr. Danesh has nothing to disclose. Dr. Petrovic has nothing to disclose. Dr. Ashikian has nothing to disclose. Dr. Arbuckle has nothing to disclose. Dr. Homafar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bronstein, Y., Danesh, M., Petrovic, M., Ashikian, N., Arbuckle, R., Homafar, H. Tags: General Neurology: Vascular Neurology Source Type: research

Neurotoxocariasis, a treatable infectious etiology of Stroke (P3.318)
Conclusions:Toxocara infection is an uncommon but treatable etiology of stroke, and should be particularly considered in patients with eosinophilia, positive serology, myocarditis and embolic strokes.Disclosure: Dr. Garcia Monco has nothing to disclose. Dr. Azkune Calle has nothing to disclose. Dr. Ruisanchez nieva has nothing to disclose. Dr. Anguizola Tamayo has nothing to disclose. Dr. Pardina Vilella has nothing to disclose. Dr. Bocos Portillo has nothing to disclose. Dr. Gomez-Beldarrain has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Monco, J. G., Calle, I. A., nieva, A. R., Tamayo, D. A., Vilella, L. P., Portillo, J. B., Gomez-Beldarrain, M. Tags: Fungal and Parasitic Disease of the Nervous System Source Type: research

Common etiologies of acute symptomatic seizures evolving from lateralized periodic discharges in patients monitored with continuous EEG (P2.233)
Conclusions:The most common high risk etiologies of acute symptomatic seizures evolving from lateralized periodic discharges in our cohort of patients were ischemic stroke, tumor, encephalitis, and subdural hematoma. Recognition of these etiologic factors may influence the duration of continuous EEG monitoring employed or the decision to institute seizure prophylaxis. A larger cohort of patients should be reviewed in a future study to confirm these findings.Disclosure: Dr. Mathew has nothing to disclose. Dr. Piran has nothing to disclose. Dr. Hantus has received personal compensation for activities with UCB Pharma as a con...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mathew, S., Piran, P., Hantus, S., Malpe, C. Tags: Epilepsy and Clinical Neurophysiology: EEG and Imaging Source Type: research

An investigation of the characteristics of outpatients with epilepsy and antiepileptic drug utilization in a multicenter cross-sectional study in China
Conclusion Findings from this study provide extensive information on clinical characteristics and utilization of AEDs in Chinese patients with epilepsy which may help physicians make well-informed clinical decisions.
Source: Epilepsy and Behavior - February 23, 2017 Category: Neurology Source Type: research

An investigation of the characteristics of outpatients with epilepsy and antiepileptic drug utilization in a multicenter cross-sectional study in China.
CONCLUSION: Findings from this study provide extensive information on clinical characteristics and utilization of AEDs in Chinese patients with epilepsy which may help physicians make well-informed clinical decisions. PMID: 28242476 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - February 23, 2017 Category: Neurology Authors: Yu P, Zhou D, Liao W, Wang X, Wang Y, Wang T, Wu Y, Lang S, Lin W, Song Y, Zhao H, Cai M, Hong Z Tags: Epilepsy Behav Source Type: research

Recurrent Hemorrhagic Venous Infarctions Caused by Thrombosis of a Pontine Developmental Venous Anomaly and Protein S Mutation
A 34-year-old man presented with an acute onset of upbeat nystagmus, slurred speech, and limb and truncal ataxias. The patient had a history of limb ataxia and gait disturbance previously treated as brainstem encephalitis with corticosteroids 3 years previously. Brain magnetic resonance imaging showed pontine developmental venous anomaly (DVA) and hemorrhagic infarction within the drainage territory of the DVA. Three months later, the patient exhibited recurrent limb ataxia, double vision, and numbness of the left side of the body.
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2016 Category: Neurology Authors: Yuri Nakamura, Kei-ichiro Takase, Takuya Matsushita, Satoshi Yoshimura, Ryo Yamasaki, Hiroyuki Murai, Kazufumi Kikuchi, Jun-ichi Kira Tags: Case Studies Source Type: research

Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome
Ramnath Santosh Ramanathan, Gayathri Sreedher, Konark Malhotra, Zain Guduru, Deeksha Agarwal, Mary Flaherty, Timothy Leichliter, Sandeep RanaAnnals of Indian Academy of Neurology 2016 19(3):399-401Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right te...
Source: Annals of Indian Academy of Neurology - July 24, 2016 Category: Neurology Authors: Ramnath Santosh Ramanathan Gayathri Sreedher Konark Malhotra Zain Guduru Deeksha Agarwal Mary Flaherty Timothy Leichliter Sandeep Rana Source Type: research