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Condition: Dilated Cardiomyopathy

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Total 155 results found since Jan 2013.

Systemic tPA Treatment for Thrombosis in a Patient with Dilated Cardiomyopathy on Berlin Heart
We present a case of thrombosis in a patient on Berlin Heart LVAD that was successfully treated with systemic alteplase.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: L.D. Glass, R. Murthy, P. Pastuszko Tags: (1357) Source Type: research

Modification of ventriculo –arterial coupling by spironolactone in nonischemic dilated cardiomyopathy
ConclusionsIn NIDCM, adding MRA to conventional anti ‐failure therapy markedly improved LV ejection fraction and reduced peripheral vascular resistance, due to both improved LV contractility and especially to enhanced V–A coupling, as Ea decreased to normal. Total circulatory performance was a sensitive indicator of both LV pump performance and th e arterial loading conditions.
Source: ESC Heart Failure - January 5, 2021 Category: Cardiology Authors: Mark A. Lawson, David E. Hansen, Deepak K. Gupta, Susan P. Bell, Douglas W. Adkisson, Ravinder R. Mallugari, Douglas B. Sawyer, Henry Ooi, Marvin W. Kronenberg Tags: Original Research Article Source Type: research

Selective hand motor cortex lesions masquerading as & #8220;Pseudoperipheral Nerve Palsy & #8221;
Bhaskara P Shelley, Prakash Harishchandra, Acharya K DevadasAnnals of Indian Academy of Neurology 2020 23(5):688-693 Strategic cortical lesions involving the hand motor cortex (HMC) presenting acutely as distal upper limb pure motor weakness certainly do need to be differentiated on clinical grounds from “pseudoperipheral palsy.” This rare phenotype can imitate peripheral motor nerve deficits and should not be easily overlooked. The? isolated “central hand and finger weakness” presenting as an acute onset of varying combinations such as pseudomedian, pseudoradial,...
Source: Annals of Indian Academy of Neurology - December 8, 2020 Category: Neurology Authors: Bhaskara P Shelley Prakash Harishchandra Acharya K Devadas Source Type: research

Outcome of CentriMag ™ extracorporeal mechanical circulatory support use in critical cardiogenic shock (INTERMACS 1) patients
ConclusionOur results demonstrate an excellent outcome with the use of the CentriMag ™ device in this seriously ill population. Despite requiring multiple procedures, over 58% of patients were discharged from hospital with 5-year survival of 46%.
Source: Indian Journal of Thoracic and Cardiovascular Surgery - September 29, 2020 Category: Cardiovascular & Thoracic Surgery Source Type: research

Clinical outcomes in patients with left ventricle trabeculation or noncompaction
AbstractTrabeculation exhibits highly varied presentations, whereas noncompaction (NC) is a specific disease entity based arithmetically on wall thickness. We aimed to evaluate the clinical implications of trabeculation and its relevance to outcomes. A total of 296 patients (age 63  ± 12 years; 64% men) with trabeculation who underwent echocardiography were retrospectively identified between January 2011 and December 2012. Analyses were conducted on distinguished trabeculation which was divided into NC (maximum noncompacted/compacted ratio ≥ 2.0) or hypertrabeculat ion (HT) (ratio <  2.0). We evaluated f...
Source: The International Journal of Cardiovascular Imaging - September 7, 2020 Category: Radiology Source Type: research

Mortality risk in dilated cardiomyopathy: the accuracy of heart failure prognostic models and dilated cardiomyopathy ‐tailored prognostic model
ConclusionsAn analysis of various HF prognostic models found them to be suboptimal for DCM patients. A self ‐developed DCM prognostic model showed improved performance over the nine other models studied. However, further validation of the prognostic model in different DCM populations is required.
Source: ESC Heart Failure - August 26, 2020 Category: Cardiology Authors: Ewa Dziewi ęcka, Matylda Gliniak, Mateusz Winiarczyk, Arman Karapetyan, Sylwia Wiśniowska‐Śmiałek, Aleksandra Karabinowska, Marcin Dziewięcki, Piotr Podolec, Paweł Rubiś Tags: Original Research Article Source Type: research

Left Atrial Myxoma Presenting as Cerebral Infarct
ACUTE embolic cerebral stroke is a major health setback for any individual, with increased mortality and morbidity. Embolus arising from cardiac chambers constitutes about 20% of ischemic strokes. Atrial fibrillation is the root cause of more than 50% of cardiogenic emboli, whereas congenital heart diseases, such as atrial septal defect, patent foramen ovale, prosthetic heart valves, rheumatic heart valvular disease, dilated cardiomyopathy, and endocarditis are predisposing factors for cardiogenic emboli.
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 5, 2020 Category: Anesthesiology Authors: Hemant Digambar Waikar, Aylliath Gosalakkal Jayakrishnan, Bodiabaduge Senaka Nimalakeerthi Bandusena, Prakash Priyadarshan, Peter Parthepan Kamalaneson, Abhaya Ileperuma, Praveen Kumar Neema, Richa Dhawan, Mark A. Chaney Tags: Case Conference Source Type: research

Left Atrial Myxoma Presenting as Cerebral Embolism
ACUTE embolic cerebral stroke is a major health setback for any individual, with increased mortality and morbidity. Embolus arising from cardiac chambers constitutes about 20% of ischemic strokes. Atrial fibrillation is the root cause of more than 50% of cardiogenic emboli, whereas congenital heart diseases, such as atrial septal defect, patent foramen ovale, prosthetic heart valves, rheumatic heart valvular disease, dilated cardiomyopathy, and endocarditis are predisposing factors for cardiogenic emboli.
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 5, 2020 Category: Anesthesiology Authors: Hemant Digambar Waikar, Aylliath Gosalakkal Jayakrishnan, Bodiabaduge Senaka Nimalakeerthi Bandusena, Prakash Priyadarshan, Peter Parthepan Kamalaneson, Abhaya Ileperuma, Praveen Kumar Neema, Richa Dhawan, Mark A. Chaney Tags: Case Conference Source Type: research

Huge thrombus formation in the left ventricle during bilateral CentriMag ventricular assist device with successful bridging to heart transplantation: a case report and review of the literature
AbstractOwing to shortage of donor hearts, the ventricular assist device is used as a bridging therapy to heart transplantation. However, thrombus formation is a critical complication during ventricular assist device circulatory support that might result in ischemic infarction of end organs. Here, we report a patient diagnosed with decompensated dilated cardiomyopathy and cardiogenic shock who underwent emergent extracorporeal life support, and subsequent temporary bilateral ventricular assistance with the CentriMag device (Levitronix LLC, Waltham, MA). Daily transthoracic echocardiography did not detect any thrombus forma...
Source: Journal of Artificial Organs - July 13, 2020 Category: Transplant Surgery Source Type: research

A Novel Extracorporeal Continuous-Flow Ventricular Assist System for Patients With Advanced Heart Failure 　- Initial Clinical Experience.
CONCLUSIONS: This novel extracorporeal VAD system with a hydrodynamically levitated centrifugal pump can safely and successfully bridge patients with advanced heart failure to subsequent therapeutic stages. PMID: 32461539 [PubMed - as supplied by publisher]
Source: Circulation Journal - May 27, 2020 Category: Cardiology Authors: Seguchi O, Fujita T, Kitahata N, Iwasaki K, Kuroda K, Nakajima S, Watanabe T, Yanase M, Fukushima S, Tsukiya T, Katagiri N, Mizuno T, Takewa Y, Hamasaki T, Onda K, Hayashi T, Yamamoto H, Tatsumi E, Kobayashi J, Fukushima N Tags: Circ J Source Type: research

Serum Chemerin Predicts the Prognosis of Patients With Dilated Cardiomyopathy.
CONCLUSION: Serum chemerin should be a potential prognostic indicator in patients with DCM. PMID: 32524978 [PubMed - in process]
Source: The Heart Surgery Forum - May 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chen D, Wang J, Fu J Tags: Heart Surg Forum Source Type: research

Cuba's Role in International Atomic Energy Agency Regional Cooperation in Cardiology.
Authors: Peix A, García B Abstract Cardiovascular diseases are the leading cause of death worldwide, and a health problem in low- and middle-income as well as high-income countries. They also constitute the main cause of death in Latin America, with ischemic heart disease as the principal cause in most countries of the region. In Cuba, heart disease is the first cause of death, followed by cancer and stroke. In its 2030 Agenda for Sustainable Development, the UN recognizes the importance of chronic non-communicable diseases, including cardiovascular diseases. Cuba has participated actively as lead partner in desig...
Source: MEDICC Review - April 28, 2020 Category: International Medicine & Public Health Tags: MEDICC Rev Source Type: research

Epidemiology and Clinical Characteristics of Atrial Fibrillation in Patients with Inherited Heart Diseases
ConclusionUp to one third of inherited heart disease patients will develop AF. While common general population risk factors are key in patients with HCM, genotype is independently associated with AF. Amongst inherited arrhythmia syndromes, AF is less common, though often occurs below the age of 50 years.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - January 11, 2020 Category: Cardiology Authors: Alexandra Butters, Julia C. Isbister, Caroline Medi, Hariharan Raju, Christian Turner, Raymond W. Sy, Christopher Semsarian, Jodie Ingles Tags: ORIGINAL ARTICLE Source Type: research

Management of patients with newly-diagnosed atrial fibrillation: Insights from the BALKAN-AF survey
ConclusionsIn BALKAN-AF survey, patients with newly-diagnosed AF were more often hospitalized, less often received OAC and were more likely to receive SAPT alone. The use of OAC for stroke prevention has not been driven by the individual patient stroke risk.
Source: IJC Heart and Vasculature - December 29, 2019 Category: Cardiology Source Type: research

Dilated cardiomyopathy mutation in the converter domain of human cardiac myosin alters motor activity and response to omecamtiv mecarbil Molecular Biophysics
We investigated a dilated cardiomyopathy (DCM) mutation (F764L) in human β-cardiac myosin by determining its motor properties in the presence and absence of the heart failure drug omecamtive mecarbil (OM). The mutation is located in the converter domain, a key region of communication between the catalytic motor and lever arm in myosins, and is nearby but not directly in the OM-binding site. We expressed and purified human β-cardiac myosin subfragment 1 (M2β-S1) containing the F764L mutation, and compared it to WT with in vitro motility as well as steady-state and transient kinetics measurements. In the absence of OM we ...
Source: Journal of Biological Chemistry - November 14, 2019 Category: Chemistry Authors: Wanjian Tang, William C. Unrath, Rohini Desetty, Christopher M. Yengo Tags: Enzymology Source Type: research