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Condition: Dilated Cardiomyopathy

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Total 155 results found since Jan 2013.

Patients Selection for Left Ventriculoplasty and Mitral Valve Surgery in Non-Ischemic Dilated Cardiomyopathy
The operative indication for dilated cardiomyopathy (DCM) is controversial. Subjects were 20 non-ischemic DCM patients. Left ventriculoplasty and mitral valve repair were conducted. Cardiac index derived from forward stroke volume significantly increased after surgery (from 1.8  ± 0.6 to 2.4 ± 0.6, P = .001). One-year survival rate was 58%. Slope in preload recruitable stroke work relationship (Mw) was an independent predictor for survival after surgery (HR, 0.936; 95%CI, 0.894–0.980; P = .005). Cut-off value of Mw for one-year survival was 42.
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Yasushige Shingu, Tomonori Ooka, Tsuyoshi Tachibana, Yoshiro Matsui Source Type: research

Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter‐Defibrillators Over Time in Ischemic and Dilated Cardiomyopathy Patients
Conclusions: These changes in clinical practice with a shift to primary prevention and rise in non‐ischemic cardiomyopathy implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real life cohort.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - May 15, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, STICHERLING CHRISTIAN, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: Original Source Type: research

The potential influence of atherogenic dyslipidemia on the severity of chronic Chagas heart disease
Conclusion: we observed that AI correlated with CCHD stages and contributed, in association with anti-B13 antibodies and age, to the prediction of systolic heart failure.RESUMO Introducción: la miocardiopatía chagásica (MCC) es la manifestación más común de la tripanosomiasis americana, causando cerca de 50.000 muertes al año. Varios factores se asocian con la gravedad de MCC. Sin embargo, la evaluación de la contribución de los principales factores de riesgo cardiovascular (FRC), como la hipertensión y la dislipidemia aterogénica (DA), a la gravedad de la MCC es escasa, a pesar de su papel bien establecido en l...
Source: Revista da Associacao Medica Brasileira - March 23, 2016 Category: Journals (General) Source Type: research

Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain
Conclusion In patients with severe secondary MR, speckle-tracking GLS shows more deteriorated LV systolic function than LVEF.
Source: European Heart Journal - March 7, 2016 Category: Cardiology Authors: Kamperidis, V., Marsan, N. A., Delgado, V., Bax, J. J. Tags: Valvular heart disease Source Type: research

MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis
Abstract Heart failure remains an important clinical burden, and mitochondrial dysfunction plays a key role in its pathogenesis. The heart has a high metabolic demand, and mitochondrial function is a key determinant of myocardial performance. In mitochondrial disorders, hypertrophic remodeling is the early pattern of cardiomyopathy with progression to dilated cardiomyopathy, conduction defects and ventricular pre-excitation occurring in a significant proportion of patients. Cardiac dysfunction occurs in approximately a third of patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like e...
Source: Heart Failure Reviews - December 28, 2015 Category: Cardiology Source Type: research

Direct epicardial assist device using artificial rubber muscle in a swine model of pediatric dilated cardiomyopathy.
CONCLUSIONS: Use of a circumferential direct epicardial assistant device resulted in improvement in hemodynamic data in a dilated cardiomyopathy model. Although there is still a need for improvements in device components, the direct cardiac assist device may be a good alternative to recent heart failure device therapies. PMID: 26659480 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - December 7, 2015 Category: Transplant Surgery Authors: Saito Y, Suzuki Y, Kondo N, Kowatari R, Daitoku K, Minakawa M, Fukuda I Tags: Int J Artif Organs Source Type: research

Dysferlin deficiency blunts β-adrenergic dependent lusitropic function of mouse heart.
This article is protected by copyright. All rights reserved. PMID: 26415898 [PubMed - as supplied by publisher]
Source: The Journal of Physiology - September 29, 2015 Category: Physiology Authors: Wei B, Wei H, Jin JP Tags: J Physiol Source Type: research

Stoke Work Index Predicts Left Ventricular Reverse Remodeling
To examine whether left ventricular stroke work index (LVSWI) predicts LV reverse remodeling after surgery for patients with ischemic dilated cardiomyopathy.
Source: Journal of Cardiac Failure - September 25, 2015 Category: Cardiology Authors: Yasushige Shingu, Satoru Wakasa, Tomonori Ooka, Tsuyoshi Tachibana, Yoshiro Matsui Source Type: research

Relationship between Myocardial Extracellular Space Expansion Estimated with Post-Contrast T1 Mapping MRI and Left Ventricular Remodeling and Neurohormonal Activation in Patients with Dilated Cardiomyopathy.
CONCLUSION: Post-contrast T1 is closely related to LV remodeling, diastolic function, and neurohormonal activation in patients with DCM. PMID: 26355278 [PubMed - in process]
Source: Korean Journal of Radiology - September 13, 2015 Category: Radiology Tags: Korean J Radiol Source Type: research

Major depressive disorder in chronic heart failure patients: Does silent cerebral infarction cause major depressive disorder in this patient population?
CONCLUSION: CHF patients have an increased prevalence of SCI and MDD. Patients with SCI have a higher prevalence of MDD compared to patients without SCI in CHF. PMID: 26363742 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - September 1, 2015 Category: Cardiology Authors: Kozdağ G, Yaluğ İ, İnan N, Ertaş G, Selekler M, Kutlu H, Kutlu A, Emre E, Çetin M, Ural D Tags: Turk Kardiyol Dern Ars Source Type: research

Adipose tissue-derived stem cells as a therapeutic tool for cardiovascular disease.
Abstract Adipose tissue-derived stem cells (ADSCs) are adult stem cells that can be easily harvested from subcutaneous adipose tissue. Many studies have demonstrated that ADSCs differentiate into vascular endothelial cells (VECs), vascular smooth muscle cells (VSMCs), and cardiomyocytes in vitro and in vivo. However, ADSCs may fuse with tissue-resident cells and obtain the corresponding characteristics of those cells. If fusion occurs, ADSCs may express markers of VECs, VSMCs, and cardiomyocytes without direct differentiation into these cell types. ADSCs also produce a variety of paracrine factors such as vascular...
Source: World Journal of Cardiology - August 26, 2015 Category: Cardiology Authors: Suzuki E, Fujita D, Takahashi M, Oba S, Nishimatsu H Tags: World J Cardiol Source Type: research

Associations of Lifetime Abstention and Past and Current Alcohol Use with Late-Life Mental Health: A Propensity Score Analysis
A recent review of studies that examined health effects of alcohol consumption concludes that habitual light-to-moderate alcohol intake (up to 1 drink per day for women and 1 or 2 drinks per day for men) is associated with lower rates of death, coronary artery disease, congestive heart failure, diabetes mellitus, and stroke (O’Keefe et al., 2014). The review also reports that excessive alcohol intake, in a dose-dependent fashion, commonly causes irreversible hypertension and atrial fibrillation, accounts for one third of all cases of nonischemic dilated cardiomyopathy, and markedly increases risks of both ischemic...
Source: Drug and Alcohol Dependence - February 16, 2015 Category: Addiction Authors: C. Nathan Marti, Namkee G. Choi, Diana M. DiNitto, Bryan Y. Choi Tags: Full length article Source Type: research