Effects of voluntary memberships and volunteering on alcohol and tobacco use across the life course: Findings from the German Socio-Economic Panel
Social participation and in particular social capital (i.e., at the collective level, social cohesion, trust, and reciprocity; at the individual level, embeddedness in social groups and access to group resources; Coleman, 1988; Putnam, 1993) can affect substance use both positively and negatively via various pathways, including social support, influence, and engagement (Berkman et al., 2000; Umberson et al., 2010) and social contagion (Skog, 1985; Villalonga-Olives and Kawachi, 2017). For instance, social networks that encourage a healthy lifestyle (social influence), create supportive environments that buffer against stre...
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Maria K. Pavlova, Matthias L ühr, Maike Luhmann Tags: Full length article Source Type: research
A content analysis of JUUL discussions on social media: Using Reddit to understand patterns and perceptions of JUUL use
Despite a decline in combustible cigarette use in recent years, use of electronic cigarettes (e-cigarettes) has increased or remained relatively stable, particularly among youth and young adults (Singh, 2016; Wang et al., 2018). E-cigarettes are now the most commonly used tobacco product among youth, with a prevalence of past 30-day use at 4.3% among middle school students and 11.3% among high school students (Jamal, 2017). While a number of adult smokers report using e-cigarettes as smoking cessation aids (Polosa et al., 2011; Dawkins et al., 2015), many youth begin using e-cigarettes without having tried other tobacco pr...
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Emma I. Brett, Elise M. Stevens, Theodore L. Wagener, Eleanor L.S. Leavens, Taylor L. Morgan, Whitney W. Cotton, Emily T. H ébert Tags: Full length article Source Type: research
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
The management of co-occurring opioid use disorder and chronic pain is challenging (Dhingra et al., 2013; Wachholtz et al., 2011). Unrelieved pain in patients with opioid use disorder is associated with medical and nonmedical use of opioids (often to self-medicate), sleep disturbance, trauma, anxiety, depression, personality disorders, and decreased dispositional optimism (Barry et al., 2009a; Barry et al., 2009b; Beitel et al., 2015; Beitel et al., 2012; Peles et al., 2009; Rosenblum et al., 2003). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Declan T. Barry, Mark Beitel, Christopher J. Cutter, David A. Fiellin, Robert D. Kerns, Brent A. Moore, Lindsay Oberleitner, Lynn M. Madden, Christopher Liong, Joel Ginn, Richard S. Schottenfeld Tags: Full length article Source Type: research
Lack of effect of transcranial direct current stimulation (tDCS) on short-term smoking cessation: Results of a randomized, sham-controlled clinical trial
Tobacco use is one of the leading causes of preventable death and illness worldwide (Global Burden of Disease Research Foundation Collaborators, 2016; WHO, 2017), yet the majority of smokers who want to quit are unable to maintain abstinence even for a few days (Babb et al., 2017; Hughes et al., 2004). Many factors contribute to relapse, and existing treatments offer support for the most prominent factors such as withdrawal symptoms and cravings (Aubin et al., 2014; Piper et al., 2011; Shiffman et al., 2006). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Mary Falcone, Leah Bernardo, E. Paul Wileyto, Cheyenne Allenby, Anne Marie Burke, Roy Hamilton, Mario Cristancho, Rebecca L. Ashare, James Loughead, Caryn Lerman Tags: Full length article Source Type: research
Nicotine pre-treatment reduces sensitivity to the interoceptive stimulus effects of commonly abused drugs as assessed with taste conditioning paradigms*
Many commonly abused drugs paradoxically increase the incentive salience of contextual stimuli (Berridge and Robinson, 1998; Flagel et al., 2009; Robinson et al., 2015; Uslaner et al., 2006) while simultaneously conditioning avoidance responses to paired orosensory stimuli (Imperio and Grigson, 2015; Jenney et al., 2016; Liu et al., 2009; Parker, 1995, 2003). This is in contrast to the effects of primarily emetic stimuli, such as lithium chloride (LiCl), which result in both conditioned place and taste avoidance (CPA and CTA, respectively; Parker, 2003; Tenk et al., 2005, 2006). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: G.C. Loney, P.J. Meyer Tags: Full length article Source Type: research
Stakeholder perspectives on implementing fentanyl drug checking: Results from a multi-site study
Fentanyl-related overdoses are an urgent public health concern in many communities in the U.S. (Ciccarone, 2017; Frank and Pollack, 2017). Fentanyl, a synthetic opioid 50-100 times more potent than morphine, is clinically used in anesthesia and for chronic pain management (Higashikawa and Suzuki, 2008; Volpe et al., 2011). In many cases, people who use drugs (PWUD) are unknowingly ingesting fentanyl. In a study among people who use drugs across British Columbia, Canada, 29% of respondents tested positive for fentanyl, 73% of whom reported not knowingly using fentanyl (Amlani et al., 2015). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Jennifer L. Glick, Tricia Christensen, Ju Nyeong Park, Michelle McKenzie, Traci C. Green, Susan G. Sherman Tags: Full length article Source Type: research
Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys
Drug addiction is a worldwide public health concern. Amphetamine-type stimulants are some of the most commonly used and abused drugs in the world (United Nations Office on Drugs and Crime, 2016). In particular, methamphetamine (METH) is a stimulant with a high potential for abuse, and its use has been increasing across the globe (United Nations Office on Drugs and Crime, 2016). METH blocks monoamine transporters and dopamine (DA) metabolism, also acting as a monoamine releaser, increasing DA concentration in the synapse of the nucleus accumbens (NAcc) (Ciccarone, 2011). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Melis Odabas-Geldiay, Hannah Shields, Lais F. Berro, Kenner C. Rice, Leonard L. Howell Tags: Short communication Source Type: research
You can ’t do this job when you are sober: Heroin use among female sex workers and the need for comprehensive drug treatment programming in Kenya
Globally, female sex workers experience disproportionate health and social harms including HIV, sexually transmitted infections (STIs), viral hepatitis, reproductive health concerns, stigma, and violence (Beyrer et al., 2015; Shannon et al., 2015). Sex workers often use alcohol and drugs for social, coping, and job-related reasons, exacerbating their vulnerabilities (Dixon et al., 2015; Li et al., 2010; Needle et al., 2008; Wechsberg et al., 2006). Unfortunately, programs often fail to acknowledge the situated logics of women ’s substance use, including that not all women are willing or even able to stop sex work or ...
Source: Drug and Alcohol Dependence - November 13, 2018 Category: Addiction Authors: Jennifer L. Syvertsen, Kawango Agot, Spala Ohaga, Angela Robertson Bazzi Tags: Full length article Source Type: research
Speed kills: Associations between methamphetamine use, HIV infection, tobacco use, and accelerated mortality among gay and bisexual men in Los Angeles, CA 20years after methamphetamine dependence treatment
The prevalence of recent methamphetamine use among gay and bisexual men (GBM) in the United States (U.S.) has been estimated as 25 –45 times higher than in the U.S. general population (Forrest et al., 2010; Mimiaga et al., 2008). While some recent studies have reported an exceptionally high mortality rate among people who use methamphetamine (Callaghan et al., 2012; Darke et al., 2017; Herbeck et al., 2015; Kuo et al., 2011; Liang et al., 2010; Stenbacka et al., 2010), only one focused explicitly on GBM, and it was limited to men with HIV infection (Carrico et al., 2014). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 11, 2018 Category: Addiction Authors: R. Colby Passaro, Keenan Ramsey, Eddy R. Segura, Jordan E. Lake, Cathy J. Reback, Jesse L. Clark, Steve Shoptaw Source Type: research
E-cigarette use and respiratory disorder in an adult sample
The use of electronic smoking devices (e-cigarettes) has increased in recent years and the prevalence of e-cigarette use is now substantial among both adolescents and adults (Jamal et al., 2017; Wilson& Wang, 2017; Zernike, 2018). Given this prevalence, it is desirable to have knowledge about the health consequences of e-cigarette use (Glantz& Bareham, 2018; Muthy, 2017). Laboratory research using animal models and cell cultures has indicated that e-cigarettes have biological effects that could lead to tissue injury (Chun et al., 2017; St. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Thomas A. Wills, Ian Pagano, Rebecca Williams, Elizabeth Tam Tags: Full length article Source Type: research
Greater Risk for Frequent Marijuana Use and Problems Among Young Adult Marijuana Users with a Medical Marijuana Card
As of 2018, more than half the states in the U.S. have legalized the use of marijuana for medical purposes. Whether passage of medical marijuana (MM) laws has caused an increase in marijuana use among young people has been challenging to discern (D ’Amico et al., 2017; Pacula et al., 2013; Pacula and Smart, 2017). Nonetheless, it is clear that both marijuana use and cannabis use disorder (CUD) has increased among young adults since the early 2000s (Caulkins et al., 2015; Grucza et al., 2016; Hasin et al., 2015; Schulenberg et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Joan S. Tucker, Anthony Rodriguez, Eric R. Pedersen, Rachana Seelam, Regina A. Shih, Elizabeth J. D ’Amico Tags: Full length article Source Type: research
Mental health functioning and severity of cannabis withdrawal among medical cannabis users with chronic pain
Cannabis withdrawal is now a codable disorder in the 5th edition of the Diagnostic and Statistical Manual (DSM-5, 2013). Considerable evidence has accumulated showing that abrupt cessation of prolonged and heavy cannabis use is associated with a variety of withdrawal symptoms, including (but not limited to) headaches, sleep disturbances, irritability, and anxiety (Bonnet and Preuss, 2017; Hesse and Thylstrup, 2013; Lee et al., 2014; Levin et al., 2010). Cannabis withdrawal symptoms can occur within 24 hours of cessation and lead to clinically meaningful distress and functional impairments (Allsop et al., 2012). (So...
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Brian E. Perron, Katlyn R. Holt, Emily Yeagley, Mark Ilgen Tags: Full length article Source Type: research
Effects of time-varying changes in tobacco and alcohol use on depressive symptoms following pharmaco-behavioral treatment for smoking and heavy drinking
The extant literature provides evidence that both smoking cessation and abstinence from alcohol (independently) predict reduced depressive symptoms over time. However, many smokers are unsuccessful in achieving sustained abstinence or are unwilling to commit to complete abstinence in the foreseeable future, e.g. (Begh et al., 2015). Similarly, many heavy drinkers report willingness and motivation to reduce their alcohol consumption but do not intend to be abstinent from alcohol (Marlatt and Witkiewitz, 2002). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: William V. Lechner, Natasha K. Sidhu, Patricia A. Cioe, Christopher W. Kahler Tags: Full length article Source Type: research
Significance of reduced number of cigarettes smoked after release from smoke-free prisons
This study is the first to reveal reduced levels of daily cigarette consumption among ex-prisoners released from smoke-free prisons. We beli eve further discussion of this finding is important, in the interest of guiding future research in the area. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Eleanor Woodward, Robyn Richmond Tags: Letter to the Editor Source Type: research
Testing the biosocial cognitive model of substance use in cannabis users referred to treatment
Cannabis is the most commonly used illicit drug worldwide (Hall, 2015). The global number of cannabis users is estimated at approximately 125 – 203 million people, or 2.8% - 4.5% of the global population (Degenhardt and Hall, 2012). Of those who ever try cannabis, it is estimated that 10% will become daily users and 20 – 30% will become weekly users (Hall and Pacula, 2003). Engaging in frequent and persistent cannabis use is associate d with increased risk for adverse outcomes including cannabis dependence (Hall and Degenhardt, 2009), long-term cognitive impairments (Solowij et al., 2002) and psychosis (van Os ...
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Zo ë E. Papinczak, Jason P. Connor, Gerald F.X. Feeney, Paul Harnett, Ross McD. Young, Matthew J. Gullo Tags: Full length article Source Type: research
Use of the Fagerstr öm Test to assess differences in the degree of nicotine dependence in smokers from five ethnic groups: The HELIUS study
The prevalence of smoking varies greatly across countries. Western European countries, such as the Netherlands, have intermediate prevalence (Ng et al., 2014) while the estimated prevalence of daily smoking in men is relatively low in African countries. At a global level, women smoke consistently less than men (Ng et al., 2014). Similar differences across ethnic populations are observed within immigrant populations in high income countries. For example, one study performed in three immigrant populations in the Netherlands showed that the prevalence of smoking is higher in Turkish and Surinamese origin men (63% and 55%, res...
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Jan van Amsterdam, Florence Vorspan, Marieke B. Snijder, Wim van den Brink, Aart H. Schene, Karien Stronks, Henrike Galenkamp, Eske M. Derks Tags: Full length article Source Type: research
Comparison of age of first drink and age of first intoxication as predictors of substance use and mental health problems in adulthood
The age of first alcohol drinking (AFD) has traditionally been regarded as an important metric when considering alcohol-related harm in populations (Grant and Dawson, 1997; Schuckit and Russell, 1983). Delaying AFD has been put forward as a public health strategy both to help reduce the harms from alcohol exposure in adolescence and to lower the incidence of later alcohol use disorder (AUD) (Donaldson, 2009; Health and Council, 2009; U.S. Department of Health and Human Services Office of the Surgeon General, 2007). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 6, 2018 Category: Addiction Authors: Giles Newton-Howes, Susan Cook, Greg Martin, James A. Foulds, Joseph M. Boden Tags: Full length article Source Type: research
Conditional probabilities of substance use disorders and associated risk factors: Progression from first use to use disorder on alcohol, cannabis, stimulants, sedatives and opioids
Substance use is common around the world, but not everyone who uses will go on to develop a substance use disorder (SUD; i.e., DSM-IV criteria for abuse and/or dependence on alcohol or other drugs). Of the 250 million adults estimated to have used drugs at least once, in 2015, approximately 11.8% experienced a SUD (UNoDC, 2017). Findings from epidemiological research report considerable variability within and between substances in relation to the proportion of people who have used a substance that develop a SUD (i.e., conditional prevalence) and the speed of transition from use to use disorder. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 3, 2018 Category: Addiction Authors: Christina Marel, Matthew Sunderland, Katherine L Mills, Tim Slade, Maree Teesson, Cath Chapman Tags: Full length article Source Type: research
Effect of menstrual cycle on ethanol drinking in rhesus monkeys
Excessive alcohol drinking and alcohol use disorder (AUD) persist as major public health problems, resulting in ~80,000 deaths and costing>$223 billion per year in the US alone (Kanny et al. 2013). The development of effective medications requires an understanding of the how characteristics of individual patients affects their response to medication. For example, sex differences in the effects of alcohol are well-documented (see Becker and Koob 2016); understanding how both alcohol and putative medications differentially affect men and women will permit development of sex-specific pharmacotherapies. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 3, 2018 Category: Addiction Authors: Sydney G. Thomas, Paul W. Czoty Tags: Full length article Source Type: research
Longitudinal patterns of amphetamine use from adolescence to adulthood: A latent class analysis of a 20-year prospective study of Australians
After cannabis, amphetamines are some of the most widely used illicit substances globally. In recent years, their use and associated harms have risen in some countries including Australia, China, Indonesia and Myanmar (Degenhardt et al., 2016; Lai et al., 2016; UNODC, 2013). Regular use of amphetamines, especially by injection or smoking, is strongly associated with psychoses, depression, intentional self-harm and suicide attempts (Darke et al., 2008; Marshall and Werb, 2010; Park and Haning, 2016). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Gary C.K. Chan, Peter Butterworth, Denise Becker, Louisa Degenhardt, Emily Stockings, Wayne Hall, George Patton Tags: Full length article Source Type: research
The relationship between smoking cessation and binge drinking, depression, and anxiety symptoms among smokers with serious mental illness
The prevalence of smoking among those with mental health disorders is two to three times higher than that of the general US population, depending on clinical diagnosis (Gfroerer et al., 2013). Those with diagnoses consistent with serious mental illness (SMI) like major depressive disorder (Crum et al., 2013; Grant and Harford, 1995) and schizophrenia (Drake and Mueser, 2002) are also more likely to engage in alcohol abuse behaviors. Furthermore, evidence suggests that there is a high prevalence of concurrent smoking and alcohol dependence; nicotine-dependent smokers have nearly 3-times higher risk of becoming alcohol depen...
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Patrick J. Hammett, Harry A. Lando, Brent C. Taylor, Rachel Widome, Darin J. Erickson, Anne M. Joseph, Barbara Clothier, Steven S. Fu Tags: Full length article Source Type: research
Laws limiting the prescribing or dispensing of opioids for acute pain in the United States: A National Systematic Legal Review
Overdose is a continuing public health crisis. According to the Centers for Disease Control and Prevention, nearly 64,000 Americans died from drug overdose in 2016 – nearly 175 every day. (Hedegaard et al., 2017) Drug overdose deaths – the majority of which are caused by opioids, either alone or in combination with other substances – now kill more Americans than did HIV/AIDS at the peak of that epidemic. (Dowell et al., 2017) (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Corey S. Davis, Amy Judd Lieberman, Hector Hernandez-Delgado, Carli Suba Source Type: research
A randomized controlled trial and economic evaluation of the Parents under Pressure Program for parents in substance abuse treatment
An increasing body of research suggests that adverse outcomes for children raised in families with parental substance-misuse emerge early in the child ’s life and are related to the quality of the parent-child relationship that significantly impacts on the child’s developing neurological (Schore, 2010) and attachment (De Wolff and van Ijzendoorn, 1997) systems (see Hatzis et al., 2017 for a review). Importantly, the quality of the caregiving r elationship is itself impacted by numerous chronic and inter-related problems that include co-occurring psychiatric disorders (Suchman et al., 2005), particularly disorde...
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Jane Barlow, Sukhdev Sembi, Helen Parsons, Sungwook Kim, Stavros Petrou, Paul Harnett, Sharon Dawe Tags: Full length article Source Type: research
Interventions to address substance use and sexual risk among gay, bisexual and other men who have sex with men who use methamphetamine: A systematic review
Across global settings, including North America, Europe, East and South-East Asia, and Australia (United Nations Office on Drugs and Crime, 2017), methamphetamine (MA) use manifests within many gay, bisexual and other men who have sex with men ’s (gbMSM) sexual and social lives (Ciketic et al., 2012). A growing body of research also indicates that the use of MA, used alone or in combination with other substances, is among the primary contemporary drivers of high-risk sexual behavior among gbMSM (e.g., unprotected anal intercourse with m ultiple concurrent partners), significantly contributing to the elevated rates of...
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Rod Knight, Mohammad Karamouzian, Anna Carson, Joshua Edward, Patrizia Carrieri, Jean Shoveller, Nadia Fairbairn, Evan Wood, Danya Fast Source Type: research
Alcohol consumption and S-Klotho plasma levels in sedentary healthy middle-aged adults: A cross sectional study
Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death (L ópez-otín et al., 2013). This deterioration is the primary risk factor for major human pathologies including cardiovascular diseases, osteoporosis, cancer and/or neurodegenerative disorders (López-otín et al., 2013). These diseases represent the major cause of morbidity and mortality in develope d countries, and implies a substantial increase in health costs (Kingsley, 2015; Wilmoth, 2000). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Lucas Jurado-Fasoli, Francisco J. Amaro-Gahete, Alejandro De-la-O, Ángel Gutiérrez, Manuel J. Castillo Tags: Full length article Source Type: research
Hepatitis C Virus genotype diversity and distribution among methadone maintenance treatment patients in Jiangsu, China
Hepatitis C virus (HCV) is the pathogen of Hepatitis C which causes chronic liver disease, cirrhosis, hepatocellular carcinoma, and liver-related mortality worldwide. Globally, the prevalence of viraemic HCV was estimated to be 1 –1.1% which meant 71.1–80 million by 2015 (2017b). In mainland China, the anti-HCV prevalence rate was 0.43–1.6% in the general population (Bennett et al., 2015; Cui and Jia, 2013), and the number would be much higher in high-risk groups, such as paid blood donors, patients on hemodialysis and heroin users. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Jing Lu, Li Zhang, Xiaoqin Xu, Yuanfang Chen, Ying Zhou, Zhi Zhang, Gengfeng Fu, Guohong Chen Tags: Full length article Source Type: research
Greater tolerance to losses in sensation seeking: Evidence from probability and delay discounting
The personality trait of sensation seeking is defined as “the tendency to take risks for varied, novel, complex and intense sensations and experiences” (Zuckerman, 1994). It has been in recent years regarded as a potential endophenotype of various risk-taking behaviors (Benjamin et al., 2001; Gottesman and Gould, 2003; Mann et al., 2017), including ri sky driving (Jonah, 1997), physical risk sports (Ruedl et al., 2012), promiscuous sexual activity (Hoyle et al., 2000), aggressive and unsocialized behaviors (Wilson and Scarpa, 2011), excessive gambling (Harris et al., 2015), and especially substance use (Bardo e...
Source: Drug and Alcohol Dependence - November 2, 2018 Category: Addiction Authors: Ya Zheng, Moqian Tian, Qi Li, Xun Liu Tags: Full length article Source Type: research
Application of Vested Interest Theory to prevention of non-medical prescription stimulant and marijuana use: Unforeseen benefits of attitude-behavior inconsistency
Attitude, an “evaluative integration of cognitions and affects experienced in relation to an object” (Crano and Prislin, 2006), was viewed by Allport (1954) as the “primary building stone in the edifice of social psychology.” Attitudes have played a central role in explaining and predicting a range of hu man actions (Bohner and Dickel, 2011; Crano and Prislin, 2006), but they are not infallible predictors of behavior (Crano, 1995; McGuire, 1985; Siegel et al., 2014). The current research acknowledges, and seeks to take advantage of this lack of perfect association between attitudes and behaviors. (S...
Source: Drug and Alcohol Dependence - October 30, 2018 Category: Addiction Authors: Jason T. Siegel, Candice D. Donaldson, William D. Crano Tags: Full length article Source Type: research
Influence of comorbid drug use disorder on receipt of evidence-based treatment for alcohol use disorder among VA patients with alcohol use disorder and Hepatitis C and/or HIV
Unhealthy alcohol use and alcohol use disorders are highly prevalent among people with hepatitis C virus (HCV) and among people with human immunodeficiency virus (HIV) (Armstrong et al., 2006; CDC, 2016; Galvan et al., 2002; Taylor et al., 2016; Tsui et al., 2016; Williams et al., 2016b), and alcohol use has unique harmful effects for persons with each of these infectious diseases. Alcohol and HCV have synergistic impacts on health. Among people with HCV, those who drink heavily are at increased risk for HCV-related liver diseases and mortality compared with those who do not (Donato et al., 2002; Fuster et al., 2014; Hutch...
Source: Drug and Alcohol Dependence - October 30, 2018 Category: Addiction Authors: Madeline C. Frost, Theresa E. Matson, Judith I. Tsui, Emily C. Williams Tags: Full length article Source Type: research
Relationship between childhood abuse and substance misuse problems is mediated by substance use coping motives, in school attending South African adolescents
Childhood abuse is typically associated with greater risk of alcohol and drug problems, in cross sectional and prospective designs, in adolescent and adults, although not all studies replicate this finding (Brady and Back, 2012; Butt et al., 2011; Konkol ÿ Thege et al., 2017; Simpson and Miller, 2002). Childhood abuse/trauma (assessed in adults) is also associated with stronger drug use coping motives, which statistically mediates the relationship between abuse/trauma and alcohol/drug problems (Goldstein et al., 2010; Grayson and Nolen-Hoeksema, 20 05; Schuck and Widom, 2001; Vilhena-Churchill and Goldstein, 2014). (S...
Source: Drug and Alcohol Dependence - October 30, 2018 Category: Addiction Authors: Lee Hogarth, Lindi Martin, Soraya Seedat Tags: Short communication Source Type: research
Randomized controlled trial of telephone monitoring with psychiatry inpatients with co-occurring substance use and mental health disorders
Substance use and mental health disorders frequently co-occur. Population-based surveys indicate that over 8.4 million adults in the US have co-occurring substance use and mental health disorders (SAMHSA, 2014). Specifically, over 30% of people with mental illness, and over 50% of people with severe mental illness, will experience a substance use disorder in their lifetime (SAMHSA, 2014). Co-occurring disorders are associated with greater symptom severity and poorer functioning than either disorder alone (Merikangas and Kalaydjian, 2007). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 29, 2018 Category: Addiction Authors: Christine Timko, Alex HS Harris, Mary Jannausch, Mark Ilgen Tags: Full length article Source Type: research
Externalizing and self-medicating: Heterogeneity among repeat DUI offenders
Driving under the influence of intoxicants (DUI) is a major public health problem facing the United States. According to 2016 data from the U.S. National Highway Traffic Safety Administration (NHTSA), 10,497 people were injured or killed in alcohol-related crashes, and 28% of all motor vehicle fatalities involved alcohol-impaired drivers that year (NHTSA, 2017). Furthermore, the estimated annual economic cost of alcohol-related accidents is roughly $49.8 billion (Blincoe et al., 2015). DUI has been dubbed one of the most publicly hazardous consequences of addiction (Nelson and Tao, 2012). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 26, 2018 Category: Addiction Authors: Sarah E. Nelson, Emily Shoov, Richard A. LaBrie, Howard J. Shaffer Tags: Full length article Source Type: research
Young adult dual combusted cigarette and e-cigarette users ’ anticipated responses to a nicotine reduction policy and menthol ban in combusted cigarettes
The Family Smoking Prevention Tobacco Control Act (FSPTCA) provided the United States (U.S.) Food and Drug Administration (FDA) with regulatory authority over the manufacture, marketing, and distribution of combusted cigarettes (CC) (U.S. Congress, 2009). The FDA is authorized to reduce the maximum allowable nicotine content in CC. Reducing nicotine in CC to a level below that which sustains dependence could help smokers to reduce smoking or quit, and decrease the likelihood of dependence in smokers (Benowitz and Henningfield, 1994; Donny et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 26, 2018 Category: Addiction Authors: Lauren R. Pacek, Jason A. Oliver, Maggie M. Sweitzer, F. Joseph McClernon Tags: Short communication Source Type: research
Electronic decision support for treatment of hospitalized smokers: A qualitative analysis of physicians ’ knowledge, attitudes, and practices
Hospitals are smoke-free environments and required to identify and offer treatment to smokers who are hospitalized. (Centers for Medicare and Medicaid Services, 2009; Fiore et al., 2012; Williams et al., 2009). Inpatients undergo a period of enforced tobacco abstinence, providing a “teachable moment” (Boudreaux et al., 2012; Buchbinder et al., 2014; Lawson and Flocke, 2009) to initiate treatment and promote long-term abstinence. Furthermore, because many admissions are for tobacco-related conditions, these acute health events may provide sufficient motivation for smokers t o quit (Boudreaux et al., 2007). (Sour...
Source: Drug and Alcohol Dependence - October 26, 2018 Category: Addiction Authors: Lauretta E. Grau, June Weiss, Teresa K. O ’Leary, Deepa Camenga, Steven L. Bernstein Tags: Full length article Source Type: research
Recreational marijuana legalization and prescription opioids received by Medicaid enrollees
The liberalization of marijuana laws has been a worldwide momentum in recent years. Following medical marijuana legalization in over half states in the US and a few countries in Europe and America, in 2012, Colorado and Washington in the US first passed laws to legalize marijuana use by adults aged 21 or older. Since then, recreational marijuana legalization has been adopted in eight states and DC where one fifth of US population live (Lawatlas, 2018). These state-wide laws emboldened other jurisdictions in the world to enable recreational marijuana market, with Uruguay and Canada passing country-level legalization in 2014...
Source: Drug and Alcohol Dependence - October 25, 2018 Category: Addiction Authors: Yuyan Shi, Di Liang, Yuhua Bao, Ruopeng An, Mark S. Wallace, Igor Grant Tags: Full length article Source Type: research
Sex, THC, and hormones: Effects on density and sensitivity of CB1 cannabinoid receptors in rats
Historically, most preclinical pharmacological research has been conducted in male animals without regard for potential sex-based variance in drug effects (Beery and Zucker, 2011). To address this sex imbalance in basic research, in 2016 the National Institutes of Health mandated consideration of sex as a biological variable in the review of grant proposals using animal models (Clayton and Collins, 2014). Consequently, research including animals of both sexes is increasing rapidly, highlighting the need to establish sex differences or the lack thereof between male and female rats in their basal, untreated state. (Source: D...
Source: Drug and Alcohol Dependence - October 25, 2018 Category: Addiction Authors: Charlotte E. Farquhar, Christopher S. Breivogel, Thomas F. Gamage, Elaine A. Gay, Brian F. Thomas, Rebecca M. Craft, Jenny L. Wiley Tags: Full length article Source Type: research
Patterns and history of prescription drug use among opioid-related drug overdose cases in British Columbia, Canada, 2015-2016
Drug overdoses involving opioids have been dramatically increasing in North America since 2000, with a more rapid rise in the last several years (Fischer et al., 2018; Rudd et al., 2016a, b; Rudd et al., 2016a, b). Opioid overdoses have been described as occurring in the context of an intertwined epidemic driven by increasing availability of prescribed and diverted opioids since the 1990s (Slavova et al., 2017; Unick et al., 2013). More recently, statistics show an unprecedented increase in drug overdose deaths that have been linked to the replacement of heroin and diverted pharmaceutical opioids with fentanyl and its anal...
Source: Drug and Alcohol Dependence - October 25, 2018 Category: Addiction Authors: Kate Smolina, Alexis Crabtree, Mei Chong, Bin Zhao, Mina Park, Christopher Mill, Christian G. Sch ütz Source Type: research
Non-fatal opioid-related overdoses among adolescents in Massachusetts 2012 –2014
The opioid epidemic in the United States has not spared adolescents. Between 1993 and 2010, emergency department visits for opioid-related overdose increased 1188% for those younger than 20 (Hasegawa et al., 2014), and annual opioid-related overdose deaths among 15-19 year-olds increased 2.3-fold from 1999 to 2015 (Curtin et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 25, 2018 Category: Addiction Authors: Avik Chatterjee, Marc R. Larochelle, Ziming Xuan, Na Wang, Dana Bernson, Michael Silverstein, Scott E. Hadland, Thomas Land, Jeffrey H. Samet, Alexander Y. Walley, Sarah M. Bagley Tags: Short communication Source Type: research
An intervention trial targeting methadone maintenance treatment providers to improve clients ’ treatment retention in China
Methadone has been widely used as an effective opioid substitution to combat both drug addiction and HIV infection (Karki et al., 2016; Wu and Clark, 2013; MacArthur et al., 2012; Mathers et al., 2009; WHO, 2009). Satisfactory outcomes of methadone maintenance treatment (MMT) are highly dependent upon treatment compliance (Caplehorn et al., 1994; Ward et al., 1999). However, client dropout is common and presents a significant challenge to MMT programs worldwide (Feelemyer et al., 2014; Lambdin et al., 2014; Proctor et al., 2015; Soyka et al., 2008), including in China (Cao et al., 2013; Sun et al., 2015; Yin et al., 2010; ...
Source: Drug and Alcohol Dependence - October 25, 2018 Category: Addiction Authors: Li Li, Zunyou Wu, Li-Jung Liang, Chunqing Lin, Sitong Luo, Xiaobin Cao, Julie Hsieh, Keming Rou Tags: Full length article Source Type: research
Methamphetamine use and cognitive function: A systematic review of neuroimaging research
Amphetamines, a group of stimulants that includes amphetamine and methamphetamine (MA), are the second most abused worldwide after cannabis (United Nations Office on Drugs and Crime, 2017a). Global prevalence for amphetamines in 2015 was estimated to be 0.8%. In some parts of the world, the numbers are higher; prevalence in North America was 2.0% and in Oceania was 1.9%. The global market for amphetamines was dominated by MA, which accounted for 72% of the global seizures of amphetamines (United Nations Office on Drugs and Crime, 2017b). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Sabrini Sabrini, Y. Wang Grace, C. Lin Joanne, Kirk Ian, E. Curley Louise Source Type: research
Differences in protective factors among U.S. Veterans with posttraumatic stress disorder, alcohol use disorder, and their comorbidity: Results from the National Health and Resilience in Veterans Study
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) frequently co-occur in the Veteran population. In a nationally representative sample of Veterans, one of every five Veterans with AUD also screened positive for PTSD (Norman et al., 2018). This rate is even higher among Veterans seeking VA care, with up to two-thirds of Veterans with AUD also having a diagnosis of PTSD (Seal et al., 2011). Comorbid PTSD/AUD is associated with more severe clinical and functional problems relative to PTSD or AUD alone, including increased risk of suicide and reduced functioning and quality of life (Blanco et al., 2013; Norma...
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Elizabeth Straus, Sonya B. Norman, Moira Haller, Steven M. Southwick, Jessica L. Hamblen, Robert H. Pietrzak Tags: Full length article Source Type: research
Prevalence, incidence, recovery, and recurrence of alcohol use disorders from childhood to age 30
Little is known about the course of alcohol use disorders (AUDs) in representative samples during high-risk periods of adolescence and early adulthood. The primary objective of this research is to describe the prevalence and course of initial AUD episodes experienced between childhood and age 30 in a regionally representative cohort sample. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: John R. Seeley, Richard F. Farmer, Derek B. Kosty, Jeff M. Gau Tags: Full length article Source Type: research
Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users
Addiction is characterized by impulsive decision making that can lead to harmful long-term consequences (Verdejo-Garcia et al., 2018). The progression from controlled, voluntary drug use to compulsive drug taking has been described as a shift from flexible prefrontal cortical control to automatic responding driven by corticostriatal circuitry (Everitt et al., 2008). The brain circuits that are implicated in addiction comprise several intrinsic functional neural networks that coordinate decision-making and learning (Laird et al., 2011; Ma et al., 2015). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Andr éa L. Hobkirk, Ryan P. Bell, Amanda V. Utevsky, Scott Huettel, Christina S. Meade Tags: Full length article Source Type: research
Perceived social status and unhealthy habits in Korea
There is a well-documented association between socioeconomic status (SES) and unhealthy behaviors such as tobacco and alcohol consumption. Lower SES individuals in Chile and Finland were found more likely to abstain from alcohol but also more likely to engage in heavy episodic drinking (Pena et al., 2017). Lower SES was also found to be associated with tobacco, cannabis, and alcohol consumption among French young adults (Redonnet et al., 2012) and with alcohol consumption in India (Kumar et al., 2018). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Younoh Kim Tags: Full length article Source Type: research
Historical trends in the grade of onset and sequence of cigarette, alcohol, and marijuana use among adolescents from 1976-2016: implications for “Gateway” patterns in adolescence
Psychoactive substance use tends to begin in adolescence and early adulthood in a predictable sequence. Adolescents who use substances most often begin with those that are licit for adults and more readily available, such as alcohol and tobacco, and then a proportion of those will experiment with marijuana and other drugs (Kandel and Kandel, 2015; Ramo et al., 2012; Wall et al., 2018). Indeed, historically, few adolescents who use marijuana have not experimented with alcohol and cigarettes beforehand. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Katherine M. Keyes, Caroline Rutherford, Richard Miech Tags: Full length article Source Type: research
Approaches for Creating Comparable Measures of Alcohol Use Symptoms: Harmonization with Eight Studies of Criminal Justice Populations
The National Institute on Drug Abuse (NIDA) and other National Institutes of Health partners initiated the STTR (Seek-Test-Treat-Retain, referencing the HIV treatment cascade) Research Harmonization Initiative to create the largest prospective data collection and harmonization effort (Chandler et al., 2015). The initiative serves as an example for creating partnerships between government agencies and study investigators at the point of project inception with the goal of eventual data harmonization (i.e., creating comparable measures in different data sets for pooled analyses across studies). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 22, 2018 Category: Addiction Authors: Andrea M. Hussong, Nisha C. Gottfredson, Dan J. Bauer, Patrick J. Curran, Maleeha Haroon, Redonna Chandler, Shoshana Y. Kahana, Joseph A.C. Delaney, Frederick L. Altice, Curt G. Beckwith, Daniel J. Feaster, Patrick M. Flynn, Michael S. Gordon, Kevin Knigh Tags: Full length article Source Type: research
PrEP awareness, eligibility, and interest among people who inject drugs in Baltimore, Maryland
People who inject drugs (PWID) have been central to the HIV/AIDS epidemic for over 30 years, with the World Health Organization estimating that about 19% are living with HIV globally (Mathers et al., 2008). In 2015, the Centers for Disease Control and Prevention (CDC) determined that 6% of HIV diagnoses in the U.S. were attributable to injection drug use (IDU) and another 3% to male-to-male sexual contact and IDU (CDC, 2016). The most successful, evidence-based HIV prevention effort targeting PWID is syringe service programs (SSPs), which have significantly reduced the incidence of HIV and HCV infections among PWID over th...
Source: Drug and Alcohol Dependence - October 22, 2018 Category: Addiction Authors: Susan G. Sherman, Kristin E. Schneider, Ju Nyeong Park, Sean T. Allen, Derrick Hunt, C. Patrick Chaulk, Brian W. Weir Tags: Full length article Source Type: research
DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults
In U.S. adults, cannabis use and cannabis use disorders (CUD) are increasing (Carliner et al., 2017; Charilaou et al., 2017; Compton et al., 2004; Gubatan et al., 2016; Hasin et al., 2015b, 2017) as is cannabis potency (ElSohly et al., 2016). Cannabis use is associated with mental and physical health problems (Hall et al., 2001; Hasin et al., 2016). Abrupt reduction or termination of long-term, frequent cannabis use is associated with a withdrawal syndrome, which includes behavioral, emotional, and physical symptoms (Budney et al., 2004). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 22, 2018 Category: Addiction Authors: Ofir Livne, Dvora Shmulewitz, Shaul Lev-Ran, Deborah S. Hasin Source Type: research