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Evaluation of epicardial and intra-myocardial fat in a patient with mitochondrial cardiomyopathy
Mitochondrial cardiomyopathy is one of the main manifestations in patients with primary mitochondrial respiratory chain disease characterized by mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) and carries a similar prognosis. The phenotype frequently includes hypertrophic cardiomyopathy; dilated cardiomyopathy and left ventricular (LV) non-compaction are rarely present . Cardiac magnetic resonance imaging (MRI) with gadolinium-based contrast agents has been widely used for evaluating the morphology and function of the left ventricle and injured myocardial tissue . Cine imaging with a stan...
Source: International Journal of Cardiology - April 15, 2013 Category: Cardiology Authors: Satoshi Okayama, Shiro Uemura, Yoshihiko Saito Tags: Online letters to the editor Source Type: research

Low-dose dobutamine induces left ventricular mechanical dyssynchrony in patients with dilated cardiomyopathy and a narrow QRS: a study using real-time three-dimensional echocardiography.
CONCLUSIONS: Dobutamine may induce LV mechanical dyssynchrony in a substantial proportion of patients with DCM and a narrow QRS. In such cases, regional LV contractile reserve does not fully contribute to an increase in global LVSV. PMID: 23473770 [PubMed - in process]
Source: Journal of Cardiology - April 1, 2013 Category: Cardiology Authors: Yagishita-Tagawa Y, Abe Y, Arai K, Yagishita D, Takagi A, Ashihara K, Shoda M, Naruko T, Itoh A, Haze K, Yoshikawa J, Hagiwara N Tags: J Cardiol Source Type: research

Cardiomyopathy in neurological disorders
Abstract: According to the American Heart Association, cardiomyopathies are classified as primary (solely or predominantly confined to heart muscle), secondary (those showing pathological myocardial involvement as part of a neuromuscular disorder) and those in which cardiomyopathy is the first/predominant manifestation of a neuromuscular disorder. Cardiomyopathies may be further classified as hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, or unclassified cardiomyopathy (noncompaction, Takotsubo-cardiomyopathy). This review focuses on seconda...
Source: Cardiovascular Pathology - February 25, 2013 Category: Cardiology Authors: Josef Finsterer, Claudia Stöllberger, Karim Wahbi Tags: Original Articles Source Type: research

Cerebral Infarction in Both Carotid and Vertebrobasilar Territories Associated with a Persistent Primitive Hypoglossal Artery with Severe Dilated Cardiomyopathy
A persistent primitive hypoglossal artery (PPHA) is a relatively rare vascular anomaly of a persistent carotid–basilar anastomosis. A 76-year-old man with severe dilated cardiomyopathy suddenly lost consciousness. A magnetic resonance imaging scan of his brain revealed extensive infarction in the carotid and vertebrobasilar territories. Magnetic resonance angiography revealed a PPHA and occlusion of the left internal carotid artery and vertebrobasilar artery. Cardioembolic infarction associated with a PPHA should be recognized as a possible cause of multiple infarctions in both the carotid and vertebrobasilar distributio...
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2012 Category: Neurology Authors: Hiroyuki Kawano, Yuichiro Inatomi, Teruyuki Hirano, Toshiro Yonehara Tags: Case Reports Source Type: research

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