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Condition: Dilated Cardiomyopathy
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Total 155 results found since Jan 2013.
Acute myocardial infarction in a patient with MELAS syndrome: a possible link?
CONCLUSIONS: In light of the recent evidence suggesting a possible link between mitochondrial disorders and atherosclerosis, we speculate that MELAS syndrome may have played a role in the pathogenesis of coronary artery disease in our patient. Further investigations are needed to confirm a pathogenetic link.PMID:35767235 | DOI:10.23736/S2724-5683.22.06021-5
Source: Atherosclerosis - June 29, 2022 Category: Cardiology Authors: Joseph Cosma Alessandro Russo Sofia Schino Martina Belli Ruggiero Mango Gaetano Chiricolo Eugenio Martuscelli Enrica G Mariano Source Type: research
Stroke in Chagas disease: from pathophysiology to clinical practice
Rev Soc Bras Med Trop. 2022 Jun 6;55:e0575. doi: 10.1590/0037-8682-0575-2021. eCollection 2022.ABSTRACTDespite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern. The disease affects approximately 6 million people, of whom 20-40% will develop cardiomyopathy over the years after the initial Trypanosoma cruzi infection. Chagas cardiomyopathy is the most serious and frequent manifestation of Chagas disease. Clinical manifestations vary widely according to the severity of myocardial dysfunction, ranging from asymptomatic ...
Source: Atherosclerosis - June 8, 2022 Category: Cardiology Authors: Tha ís Aparecida Reis Lage Julia Teixeira Tupinamb ás Lucas Bretas de P ádua Matheus de Oliveira Ferreira Amanda Cambraia Ferreira Antonio Lucio Teixeira Maria Carmo Pereira Nunes Source Type: research
En-571-02 screening for putative pathogenic variants in dilated cardiomyopathy genes identifies early disease and predicts mortality
Dilated cardiomyopathy (DCM) can present with the sentinel event of sudden cardiac death, as well as heart failure, ECG abnormalities, atrial fibrillation or stroke. Data are limited regarding genetic screening and the mortality associated with DCM in a general population.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Ravi Shah, Babken Asatryan, Ghaith Sharaf Dabbagh, Mohammed Khanji, Stefan van Duijvenboden, Daniele Muser, Andrew Paul Landstrom, Christopher Semsarian, Virend Somers, Patricia B. Munroe, Anwar A. Chahal Source Type: research
Mechanical Thrombectomy for M1 Subocclusive Thrombus With Lateral Lenticulostriate Artery Occlusion: A Case Report and Literature Review
This article describes a treatment strategy for M1 subocclusive thrombus, focusing on the indications for mechanical thrombectomy. A 58-year-old male on admission for pneumonia had a sudden onset of dysarthria and motor deficits. He has a history of dilated cardiomyopathy and underwent left ventricular assist device implantation 3 years ago. At onset, his National Institutes of Health Stroke Scale (NIHSS) score was nine. Computed tomography angiography demonstrated a filling defect in the distal right M1 segment of the middle cerebral artery. Angiography confirmed the presence of a subocclusive thrombus within the distal r...
Source: Frontiers in Neurology - February 7, 2022 Category: Neurology Source Type: research
GSE195617 Neuronal and cardiac toxicity of pharmacological compounds identified through transcriptomic analysis of human pluripotent stem cell-derived embryoid bodies
In this study, we used human induced pluripotent stem cell (hiPSC)-derived embryoid bodies (EB) as an in vitro model to investigate the embryotoxic effects of a carefully selected set of pharmacological compounds. Morphology, viability, and differentiation potential were investigated after exposing EBs to folic acid, all-trans-retinoic acid, dexamethasone, and valproic acid for 15 days. The results showed that the compounds differentially repressed cell growth, compromised morphology, and triggered apoptosis in the EBs. Further, transcriptomics was employed to compare subtle temporal changes between treated and untreated c...
Source: GEO: Gene Expression Omnibus - January 31, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Non-invasive right ventriculo-arterial coupling as a rehospitalization predictor in dilated cardiomyopathy: A comparison of five different methods
CONCLUSION: RVFW-LS/PASP and RVEF/PASP as non-invasive estimates of RVPAC are independent predictors of HF rehospitalization in patients with DCM.PMID:34939658 | DOI:10.33963/KP.a2021.0190
Source: Polish Heart Journal - December 23, 2021 Category: Cardiology Authors: Aura V îjîiac Vlad B ătăilă Sebastian Onciul Violeta Verinceanu Claudia Guzu Silvia Deaconu Ioana Petre Alina Sc ărlătescu Diana Zamfir Maria Doroban ţu Source Type: research
