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Condition: Alzheimer's
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Total 2642 results found since Jan 2013.
UCLA brain-imaging tool and stroke risk test help identify cognitive decline early
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.
The connection between stroke risk and cognitive decline has been well established by previous research. Individuals with higher stroke risk, as measured by factors like high blood pressure, have traditionally performed worse on tests of memory, attention and abstract reasoning.
The current small study demonstrated that not only stroke risk, but also the burden of plaques and tangles, as measured by a UCLA brain scan, may influence c...
Source: UCLA Newsroom: Health Sciences - April 3, 2013 Category: Universities & Medical Training Source Type: news
Peripheral biomarkers of stroke: Focus on circulatory microRNAs
This article also reviews research investigating circulatory miRNAs as peripheral biomarkers of stroke.
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - August 9, 2016 Category: Molecular Biology Source Type: research
Increased risk for dementia both before and after stroke: A population-based study in women followed over 44 years.
DISCUSSION: There is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke.
PMID: 29936145 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 25, 2018 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Prediction of post-stroke cognitive impairment using brain FDG PET: deep learning-based approach
CONCLUSION: The DL-based cognitive signature using FDG PET was successfully transferred to an independent stroke cohort. It is suggested that DL-based cognitive evaluation using FDG PET could be utilized as an objective biomarker for cognitive dysfunction in patients with cerebrovascular diseases.PMID:34599654 | DOI:10.1007/s00259-021-05556-0
Source: Molecular Medicine - October 2, 2021 Category: Molecular Biology Authors: Reeree Lee Hongyoon Choi Kwang-Yeol Park Jeong-Min Kim Ju Won Seok Source Type: research
Prevention of poststroke cognitive decline: ASPIS – a multicenter, randomized, observer‐blind, parallel group clinical trial to evaluate multiple lifestyle interventions – study design and baseline characteristics
ConclusionThe recruitment was successful and the groups are balanced regarding potential confounding variables. The study will provide essential data about the feasibility and efficacy of lifestyle intervention after stroke in order to develop a new approach to prevent cognitive decline in patients with mild ischemic stroke.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Michael Brainin, Karl Matz, Matthias Nemec, Yvonne Teuschl, Alexandra Dachenhausen, Susanne Asenbaum‐Nan, Christian Bancher, Berthold Kepplinger, Stefan Oberndorfer, Michaela Pinter, Peter Schnider, Jaakko Tuomilehto, Tags: Protocols Source Type: research
Newly Diagnosed Dementia and Increased Risk of Hemorrhagic Stroke: A Nationwide Population-based Study.
Conclusion: Individuals with dementia, especially Alzheimer's disease, are at greater risk of developing stroke, especially in intracerebral and subarachnoid hemorrhage than patients without dementia. Early mental screening programs and health education should be initiated for dementia patients.
PMID: 24484279 [PubMed - as supplied by publisher]
Source: Current Alzheimer Research - January 31, 2014 Category: Neurology Authors: Wang HK, Tsai KJ, Huang CY, Wang LC, Lu K, Chen HJ, Lin CW, Lee YJ, Fang PH, Chang LC, Li YC Tags: Curr Alzheimer Res Source Type: research
Microbleeds, Mortality, and Stroke in Alzheimer Disease The MISTRAL Study
Conclusions and RelevanceIn patients with AD, the presence of nonlobar microbleeds was associated with an increased risk for cardiovascular events and cardiovascular mortality. Patients with lobar microbleeds had an increased risk for stroke and stroke-related mortality, indicating that these patients should be treated with the utmost care.
Source: JAMA Neurology - March 23, 2015 Category: Neurology Source Type: research
Increased risk for dementia both before and after stroke: A population-based study in women followed over 44 years
Discussion There is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - June 22, 2018 Category: Geriatrics Source Type: research
Increased risk for dementia both before and after stroke: A population-based study in women followed over 44 years
DiscussionThere is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 5, 2018 Category: Geriatrics Source Type: research
Stroke and dementia risk: A systematic review and meta-analysis.
DISCUSSION: Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia.
PMID: 30177276 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - September 6, 2018 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants
Publication date: Available online 22 October 2018Source: NeuroImage: ClinicalAuthor(s): Mohamed Salah Khlif, Natalia Egorova, Emilio Werden, Alberto Redolfi, Marina Bocardi, Charles S. DeCarli, Even Fletcher, Baljeet Singh, Qi Li, Laura Bird, Amy BordtmannAbstractManual quantification of the hippocampal atrophy state and rate is time consuming and prone to poor reproducibility, even when performed by neuroanatomical experts. The automation of hippocampal segmentation has been investigated in normal aging, epilepsy, and in Alzheimer's disease. Our first goal was to compare manual and automated hippocampal segmentation in i...
Source: NeuroImage: Clinical - October 22, 2018 Category: Radiology Source Type: research
Preventing dementia by preventing stroke: The Berlin Manifesto.
This article summarizes the evidence for translation into action.
PMID: 31327392 [PubMed - in process]
Source: The Journal of Alzheimers Association - July 24, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Neuroprotective Mechanisms of Glucagon-Like Peptide-1-Based Therapies in Ischemic Stroke: An Update Based on Preclinical Research
The public and social health burdens of ischemic stroke have been increasing worldwide. Hyperglycemia leads to a greater risk of stroke. This increased risk is commonly seen among patients with diabetes and is in connection with worsened clinical conditions and higher mortality in patients with acute ischemic stroke (AIS). Therapy for stroke focuses mainly on restoring cerebral blood flow (CBF) and ameliorating neurological impairment caused by stroke. Although choices of stroke treatment remain limited, much advance have been achieved in assisting patients in recovering from ischemic stroke, along with progress of recanal...
Source: Frontiers in Neurology - March 15, 2022 Category: Neurology Source Type: research
Genetically Predicted Frailty Index and Risk of Stroke and Alzheimer's Disease
CONCLUSIONS: The MR study suggested that genetically predicted FI may be associated with an increased risk of any stroke. Subgroup analysis indicated a suggestive association between genetically predicated FI and the risk of LAS. The underlying mechanisms need further warranted.PMID:35318774 | DOI:10.1111/ene.15332
Source: Atherosclerosis - March 23, 2022 Category: Cardiology Authors: Weishi Liu Luyang Zhang Hui Fang Yuan Gao Kai Liu Shen Li Hongbing Liu Xin Wang Chen Liu Bo Song Zongping Xia Yuming Xu Source Type: research
