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Total 2642 results found since Jan 2013.

Midlife Orthostatic Hypotension May Increase Risk of Dementia, Stroke
People with orthostatic hypotension (an excessive drop in blood pressure when standing up that can lead to dizziness and fainting) in midlife may be more likely than those without the condition to develop stroke and dementia later in life, according to astudy inNeurology.“The presence of orthostasis, especially in midlife, might identify individuals in whom more careful monitoring or risk factor management might be warranted,” wrote lead author Andreea Rawlings, Ph.D., of the Johns Hopkins Bloomberg School of Public Health and colleagues.These findings come from an analysis of data from 11,709 participants without a hi...
Source: Psychiatr News - July 30, 2018 Category: Psychiatry Tags: Alzheimer's Alzheimer's risk factors dementia dizziness orthostatic hypotension stroke Source Type: research

Apolipoprotein E Genotypes Associated with Alzheimer Disease and Concomitant Stroke
Conclusions: The present study is the first to establish a relationship between APOE ε4 and concomitant AD and stroke in the Tunisian population.
Source: Journal of Stroke and Cerebrovascular Diseases - July 22, 2013 Category: Neurology Authors: Najiba Fekih-Mrissa, Sarra Klai, Meriem Mrad, Malek Mansour, Jamel Zaouali, Nasreddine Gritli, Ridha Mrissa Tags: Original Articles Source Type: research

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia Clinical Sciences
Conclusions— Adherence to the American Heart Association’s ideal CVH factors and behaviors, particularly in midlife, may protect against cerebrovascular disease and dementia.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Pase, M. P., Beiser, A., Enserro, D., Xanthakis, V., Aparicio, H., Satizabal, C. L., Himali, J. J., Kase, C. S., Vasan, R. S., DeCarli, C., Seshadri, S. Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Incidence of stroke in people with Alzheimer disease: A national register-based approach
Conclusions: Our findings suggest that persons with AD dementia, especially younger patients, have higher risk of hemorrhagic strokes.
Source: Neurology - January 21, 2013 Category: Neurology Authors: Tolppanen, A.-M., Lavikainen, P., Solomon, A., Kivipelto, M., Soininen, H., Hartikainen, S. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Vitamin B may reduce risk of stroke
Researchers have uncovered evidence that suggests vitamin B supplements could help to reduce the risk of stroke, according to a study published in the journal Neurology. Vitamin B supplements are said to be beneficial for many health issues, including stress, anxiety, depression, dementia, Alzheimer's disease and heart disease. However, according to Xu Yuming of Zhengzhou University in Zhengzhou, China, previous studies have conflicting findings regarding the use of vitamin B supplements and stroke or heart attack...
Source: Health News from Medical News Today - September 19, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Cerebral Amyloid Angiopathy Is Associated With Executive Dysfunction and Mild Cognitive Impairment Clinical Sciences
Conclusions— Mild cognitive impairment is very prevalent in CAA. The overall cognitive profile of CAA is more similar to that seen in vascular cognitive impairment rather than Alzheimer’s disease. White matter ischemic lesions may underlie some of the impaired processing speed in CAA.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Case, N. F., Charlton, A., Zwiers, A., Batool, S., McCreary, C. R., Hogan, D. B., Ismail, Z., Zerna, C., Coutts, S. B., Frayne, R., Goodyear, B., Haffenden, A., Smith, E. E. Tags: Cerebrovascular Disease/Stroke, Cognitive Impairment, Intracranial Hemorrhage Clinical Sciences Source Type: research

Cerebral Hypoperfusion and Other Shared Brain Pathologies in Ischemic Stroke and Alzheimer ’s Disease
AbstractNewly emerged evidence reveals that ischemic stroke and Alzheimer ’s disease (AD) share pathophysiological changes in brain tissue including hypoperfusion, oxidative stress, immune exhaustion, and inflammation. A mechanistic link between hypoperfusion and amyloid β accumulation can lead to cell damage as well as to motor and cognitive deficits. This review will discuss decreased cerebral perfusion and other related pathophysiological changes common to both ischemic stroke and AD, such as vascular damages, cerebral blood flow alteration, abnormal expression of amyloid β and tau proteins, as well as behavioral an...
Source: Translational Stroke Research - October 2, 2017 Category: Neurology Source Type: research

C-Reactive Protein Can Be an Early Predictor of Poststroke Apathy in Acute Ischemic Stroke Patients
Apathy is a multidimensional syndrome referring to a primary lack of motivation that occurs frequently in survivors of stroke. Higher C-reactive protein (CRP) level was associated with higher apathy scores among Alzheimer disease cases. However, data on the relationship between CRP levels and apathy in patients with stroke are lacking. So, we hypothesized an association between CRP and poststroke apathy (PSA).
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2018 Category: Neurology Authors: Liping Chen, Siqing Xiong, Yi Liu, Meiqing Lin, Jirui Wang, Renjia Zhong, Jiuhan Zhao, Wenjing Liu, Lu Zhu, Xiuli Shang Source Type: research

Association Between Small Vessel Disease Markers, Medial Temporal Lobe Atrophy and Cognitive Impairment After Stroke: A Systematic Review and Meta-Analysis
Two-thirds of stroke survivors suffer from cognitive impairment, and up to one-third of them progress to dementia. However, the underlying pathogenesis is complex and controversial. Recent evidence has found that cerebral small vessel disease (SVD) markers and the Alzheimer's disease (AD) neuroimaging marker medial temporal lobe atrophy (MTLA), alone or in combination, contribute to the pathogenesis of poststroke cognitive impairment (PSCI). In the present systematic review and meta-analysis, we synthesized proof for these neuroimaging risk factors among stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - November 20, 2020 Category: Neurology Authors: Furu Wang, Sunyu Hua, Yue Zhang, Hongchang Yu, Zhongshuai Zhang, Jiangtao Zhu, Rong Liu, Zhen Jiang Source Type: research

In Stroke And Other Neurological Disorders, Nitric Oxide Damages Neurons And Blocks The Brain's Ability To Repair Itself
Nitric oxide, a gaseous molecule produced in the brain, can damage neurons. When the brain produces too much nitric oxide, it contributes to the severity and progression of stroke and neurodegenerative diseases such as Alzheimer's. Researchers at Sanford-Burnham Medical Research Institute recently discovered that nitric oxide not only damages neurons, it also shuts down the brain's repair mechanisms. Their study was published by the Proceedings of the National Academy of Sciences the week of February 4...
Source: Health News from Medical News Today - February 7, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Bryostatin Improves Survival and Reduces Ischemic Brain Injury in Aged Rats After Acute Ischemic Stroke Basic Sciences
Conclusions— Repeated bryostatin administration post-MCAO protected the brain from severe neurological injury post-MCAO. Bryostatin treatment improved survival rate, reduced lesion volume, salvaged tissue in infarcted hemisphere by reducing necrosis and peri-infarct astrogliosis, and improved functional outcome after MCAO.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Tan, Z., Turner, R. C., Leon, R. L., Li, X., Hongpaisan, J., Zheng, W., Logsdon, A. F., Naser, Z. J., Alkon, D. L., Rosen, C. L., Huber, J. D. Tags: Basic Sciences Source Type: research

Strong Reduction of Low-Density Lipoprotein Receptor/Apolipoprotein E Expressions by Telmisartan in Cerebral Cortex and Hippocampus of Stroke Resistant Spontaneously Hypertensive Rats
Conclusions: These findings suggest that a long-term treatment with telmisartan directly improved neuronal lipid metabolism in the cerebral cortex and hippocampus of SHR-SR, mainly improving LDL-R and ApoE metabolism (SHR/Low) with a small additive benefit by BP lowering (SHR/High), which could provide a preventative approach in patients with hypertension at risk of Alzheimer disease.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2014 Category: Neurology Authors: Yun Zhai, Toru Yamashita, Tomoko Kurata, Yusuke Fukui, Kota Sato, Syoichiro Kono, Wentao Liu, Yoshio Omote, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research

Medical News Today: Could Alzheimer's drugs or antidepressants help stroke patients?
Researchers reviewing drugs to help in rehabilitation after stroke propose antidepressants or drugs used in Alzheimer's as possibilities.
Source: Health News from Medical News Today - October 23, 2015 Category: Consumer Health News Tags: Stroke Source Type: news

Role of Vascular Disease in Alzheimer-Like Progressive Cognitive Impairment Controversies in Stroke
Source: Stroke - January 25, 2016 Category: Neurology Authors: Viswanathan, A., Greenberg, S. M., Scheltens, P. Tags: Cognitive Impairment Controversies in Stroke Source Type: research