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Condition: Abdominal Aortic Aneurysm

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Total 234 results found since Jan 2013.

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms Genetics
Conclusions Although there was no evidence for polygenic overlap between IAs, AAAs, and TAAs, we found nominally significant effects of two established risk loci for IAs and TAAs in AAAs. These two loci will require further replication.
Source: JAHA:Journal of the American Heart Association - July 13, 2016 Category: Cardiology Authors: van t Hof, F. N. G., Ruigrok, Y. M., Lee, C. H., Ripke, S., Anderson, G., de Andrade, M., Baas, A. F., Blankensteijn, J. D., Böttinger, E. P., Bown, M. J., Broderick, J., Bijlenga, P., Carrell, D. S., Crawford, D. C., Crosslin, D. R., Ebeling, C., Tags: Inflammation, Vascular Biology, Ischemic Stroke Genetics Source Type: research

Risk factors associated with increased prevalence of abdominal aortic aneurysm in women
ConclusionThis report should stimulate consideration of a targeted AAA screening programme for women aged over 65 years.
Source: British Journal of Surgery - June 23, 2016 Category: Surgery Authors: M. Chabok, A. Nicolaides, M. Aslam, M. Farahmandfar, K. Humphries, N. Z. Kermani, J. Coltart, N. Standfield Tags: Original article Source Type: research

Prevalence of Abdominal Aortic Aneurysm in Men Aged 65-74 Years in a Metropolitan Area in North-East Spain.
CONCLUSIONS: The current screening prevalence of AAA among men aged 65-74 years in a metropolitan area in north-east Spain is similar to that in northern Europe. Smoking, myocardial infarction, and height were associated with the presence of AAA. PMID: 27252078 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - May 28, 2016 Category: Surgery Authors: Salvador-González B, Martín-Baranera M, Borque-Ortega Á, Sáez-Sáez RM, de Albert-Delas Vigo M, Carreño-García E, Tarín-Masriera L, Badia-Millán P, Martínez-Gil M, Torrabadella-Fàbrega J Tags: Eur J Vasc Endovasc Surg Source Type: research

What Should the Optimal Systolic Blood Pressure Goal Be in Treating Older Persons with Hypertension?
Hypertension is a major risk factor for cardiovascular disease in the elderly.1 Hypertension occurs in 69% of persons with a first myocardial infarction,2 in 77% of those with a first stroke,2 in 74% of individuals with congestive heart failure,2 and in 60% of older adults with peripheral artery disease.3 Hypertension is also a major risk factor in older adults for dissecting aortic aneurysm, sudden cardiac death, angina pectoris, chronic kidney disease, left ventricular hypertrophy, thoracic and abdominal aortic aneurysms, atrial fibrillation, diabetes mellitus, the metabolic syndrome, vascular dementia, Alzheimer disease...
Source: Journal of the American Medical Directors Association - May 19, 2016 Category: Health Management Authors: Wilbert S. Aronow Tags: Editorial Source Type: research

Androgen receptor (AR) in cardiovascular diseases
Cardiovascular diseases (CVDs) are still the highest leading cause of death worldwide. Several risk factors have been linked to CVDs, including smoking, diabetes, hyperlipidemia, and gender among others. Sex hormones, especially the androgen and its receptor, androgen receptor (AR), have been linked to many diseases with a clear gender difference. Here, we summarize the effects of androgen/AR on CVDs, including hypertension, stroke, atherosclerosis, abdominal aortic aneurysm (AAA), myocardial hypertrophy, and heart failure, as well as the metabolic syndrome/diabetes and their impacts on CVDs. Androgen/AR signaling exacerba...
Source: Journal of Endocrinology - April 28, 2016 Category: Endocrinology Authors: Huang, C.-K., Lee, S. O., Chang, E., Pang, H., Chang, C. Tags: Review Source Type: research

Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: the EPIC-Norfolk prospective population study
Conclusion The heterogeneity in the risk factor–CVD associations supports the concept of pathophysiological differences between atherosclerotic CVD manifestations and could have implications for CVD prevention.
Source: European Heart Journal - March 14, 2016 Category: Cardiology Authors: Stoekenbroek, R. M., Boekholdt, S. M., Luben, R., Hovingh, G. K., Zwinderman, A. H., Wareham, N. J., Khaw, K.-T., Peters, R. J. G. Tags: Prevention and epidemiology Source Type: research

To intervene or not? A man with multidrug-resistant hypertension, endovascular abdominal aneurysm repair, bilateral renal artery stenosis and end-stage renal disease salvaged with renal artery stenting.
We report the case of a 69-year-old man with uncontrolled multidrug-resistant secondary hypertension following a 10 year history of endovascular abdominal aortic aneurysm repair, with suprarenal fixation and concurrent angioplasty with stenting of the left renal artery for atherosclerotic renal disease, and progressive chronic kidney disease. Renal scintigraphy revealed complete loss of the right kidney's and severe reduction of the left kidney's perfusion and function. Following recent evidence and consultation with vascular surgeons regarding the technical difficulties of any procedure, escalation of antihypertensive tre...
Source: Blood Pressure - February 14, 2016 Category: Hematology Tags: Blood Press Source Type: research

Endovascular repair or open repair for ruptured abdominal aortic aneurysm: a Cochrane systematic review
Conclusions Outcomes between eEVAR and open repair, specifically 30-day mortality, are similar. However, further high-quality trials are required, as the paucity of data currently limits the conclusions.
Source: BMJ Open - February 12, 2016 Category: Journals (General) Authors: Badger, S. A., Harkin, D. W., Blair, P. H., Ellis, P. K., Kee, F., Forster, R. Tags: Open access, Cardiovascular medicine, Evidence based practice, Surgery Research Source Type: research

Increasing Evidence for an Association Between Periodontitis and Cardiovascular Disease.
Abstract Periodontitis is a chronic inflammatory disease caused by bacterial colonisation, which results in destruction of the tissues between the tooth surface and gingiva, loss of connective tissue attachment, erosion of alveolar bone and tooth loss.(1) Periodontitis is common and increases with age. In a US survey about half of adults aged over 30 years have some periodontitis and almost 10% have severe disease.(2) Evidence for an association between periodontitis and atherosclerotic vascular disease, including stroke, myocardial infarction, peripheral vascular disease, abdominal aortic aneurysm, coronary heart...
Source: Circulation - January 13, 2016 Category: Cardiology Authors: Stewart R, West M Tags: Circulation Source Type: research

Cardiac risk stratification in patients undergoing endovascular aortic repair.
Authors: Biagi P, de Donato G, Setacci C Abstract Endovascular aortic repair (EVAR) for abdominal aortic aneurysms (AAA) is the preferred first treatment option in case of patients with advanced age and/or fit anatomy owing to shorter length of in hospital staying, less complications or laparotomy-related re- interventions, and lower initial costs. Although it is a less-invasive intervention, EVAR entails a risk similar to that of open aortic procedures for medical comorbidities, and a perioperative clinical evaluation is mandatory to minimize the early and late cardiovascular risk. In this brief review the determi...
Source: Minerva Cardioangiologica - November 18, 2015 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Intervention Associated Acute Kidney Injury and Long-Term Cardiovascular Outcomes
Background: Acute kidney injury (AKI) has been associated with all-cause short- and long-term mortality. However, its association with cardiovascular (CV) events remains unclear. We sought to investigate this in patients undergoing open (OAR) or endovascular (EVAR) abdominal aortic aneurysm repair, as they are likely to develop both AKI and CV morbidity. A meta-analysis was subsequently performed to confirm this in other CV-interventions. Methods: AKI-incidence was assessed in a multicentre-cohort of 1,068 patients undergoing EVAR (947 individuals) or OAR electively using the ‘Acute Kidney Injury Network' criteria. A com...
Source: American Journal of Nephrology - October 24, 2015 Category: Neurology Source Type: research

Intervention Associated Acute Kidney Injury and Long-Term Cardiovascular Outcomes.
CONCLUSION: AKI is associated with long-term CV events after surgery or endovascular intervention. PMID: 26495853 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - October 24, 2015 Category: Urology & Nephrology Authors: Saratzis A, Harrison S, Barratt J, Sayers RD, Sarafidis PA, Bown MJ Tags: Am J Nephrol Source Type: research

Fibrinolytic PLGA nanoparticles for slow clot lysis within abdominal aortic aneurysms attenuate proteolytic loss of vascular elastic matrix
Publication date: 1 February 2016 Source:Materials Science and Engineering: C, Volume 59 Author(s): Balakrishnan Sivaraman, Andrew Sylvester, Anand Ramamurthi Abdominal aortic aneurysms (AAAs) involve chronic overexpression of proteases in the aortic wall that result in disruption of elastic fibers and consequent loss of vessel elasticity. Nearly 75% of AAAs contain flow-obstructing, fibrin-rich intraluminal thrombi (ILT), which act as a) a bioinert shield, protecting the underlying AAA wall from high hemodynamic stresses, and b) a reservoir of inflammatory cells and proteases that cause matrix breakdown. For these re...
Source: Materials Science and Engineering: C - October 24, 2015 Category: Materials Science Source Type: research

The relation between the presence of cardiovascular disease and vascular risk factors in offspring and the occurrence of new vascular events in their parents already at high vascular risk
Conclusions Presence of cardiovascular disease, hypertension, hypercholesterolemia, and diabetes in offspring, with diabetes mellitus being the most contributing cardiovascular risk factor, is related to an increased risk of developing new or subsequent vascular events in patients already at high vascular risk.
Source: American Heart Journal - September 19, 2015 Category: Cardiology Source Type: research

How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People.
CONCLUSIONS: -The majority of initial presentations of CVD are neither MI nor ischemic stroke, yet most primary prevention studies focus on these presentations. Sex has differing associations with different CVDs, with implications for risk prediction and management strategies. Clinical Trial Registration Information-www.clinicaltrials.gov. Identifier: NCT01164371. PMID: 26330414 [PubMed - as supplied by publisher]
Source: Circulation - September 1, 2015 Category: Cardiology Authors: George J, Rapsomaniki E, Pujades-Rodriguez M, Shah AD, Denaxas S, Herrett E, Smeeth L, Timmis A, Hemingway H Tags: Circulation Source Type: research