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Condition: Abdominal Aortic Aneurysm

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Total 234 results found since Jan 2013.

The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
Curr Opin Lipidol. 2023 Jul 28. doi: 10.1097/MOL.0000000000000890. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: To explore the multiple roles that lysophosphatidic acid (LPA) plays in vascular disease and atherosclerosis.RECENT FINDINGS: A high-fat high-cholesterol diet decreases antimicrobial activity in the small intestine, which leads to increased levels of bacterial lipopolysaccharide in the mucus of the small intestine and in plasma that increase systemic inflammation, and enhance dyslipidemia and aortic atherosclerosis. Decreasing LPA production in enterocytes reduces the impact of the diet. LPA signaling inhibit...
Source: Atherosclerosis - July 27, 2023 Category: Cardiology Authors: Arnab Chattopadhyay Srinivasa T Reddy Alan M Fogelman Source Type: research

Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm
Conclusions In AAA, sLOX-1 was differently affected by age, cardiometabolic diseases, and corresponding medical therapies. Comparison with nonatherosclerotic disease would be beneficial to further elucidate the diagnostic potential of sLOX-1, although it was not useful for risk stratification. Aneurysmal LOX-1 mRNA expression was increased and positively associated with smooth muscle cells and collagen content, suggesting that LOX-1 is eventually not deleterious in human AAA and could counteract AAA rupture.PMID:37421287 | DOI:10.1161/JAHA.122.027537
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Anja Hofmann Yazan Khorzom Anna Klimova Steffen Wolk Albert Busch Pamela Sabarstinski Margarete M üglich Dmitry Egorov Irakli Kopaliani David M Poitz Marvin Kapalla Bianca Hamann Frieda Frank Christian J änichen Coy Brunssen Henning Morawietz Christian Source Type: research

Procedural and long-term outcomes of elective endovascular abdominal aortic aneurysm repair in octogenarians
CONCLUSION: In octogenarian patients with AAA, EVAR represents a safe procedure both during the index hospitalization and during long-term follow-up.PMID:37355984 | DOI:10.24875/ACM.22000289
Source: Archivos de Cardiologia de Mexico - June 25, 2023 Category: Cardiology Authors: Fernando Garagoli Juan Guido-Chiabrando Jos é Gaspar-Chas Mart ín Rabellino Ignacio Mart ín Bluro Source Type: research

Surgical implementation gap: an interrupted time series analysis with interviews examining the impact of surgical trials on surgical practice in England
Conclusion While practice does not always change in the direction indicated by clinical trials, our results suggest that individuals, official committees and professional societies do assimilate trial evidence. Decision-makers seem to respond to the totality of evidence such that there are often plausible reasons for not adopting the evidence of any one trial in isolation.
Source: BMJ Quality and Safety - May 18, 2023 Category: General Medicine Authors: Schmidtke, K. A., Evison, F., Grove, A., Kudrna, L., Tucker, O., Metcalfe, A., Bradbury, A. W., Bhangu, A., Lilford, R. Tags: Open access, Editor's choice Original research Source Type: research

High prevalence of abdominal aortic aneurysm in older men with cerebrovascular disease: Evaluation of a local screening program
This report evaluates the results of a decade's operation of a local screening program for AAA in this selected neurologic population.MethodsMen aged ≥60 years and admitted to the neurology ward of a community-based hospital in the Netherlands from 2006 to 2017 with a diagnosis of TIA or stroke were selected for screening. The diameter of the abdominal aorta was assessed by abdominal ultrasonography. Patients with detected AAA were referred for evaluation by a vascular surgeon.ResultsAAA was detected in 72 of 1,035 screened patients (6.9%). AAAs with a diameter of 3.0–3.9 cm accounted for 61.1% of the total aneurysms f...
Source: Frontiers in Neurology - April 11, 2023 Category: Neurology Source Type: research

Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 7, 2023 Category: Surgery Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research

Effect of socioeconomic status on patients undergoing elective abdominal aortic aneurysm repair in a publicly funded health care system
CONCLUSION: Socioeconomic status does not appear to affect short- or long-term mortality after AAA repair in a publicly funded health care system. Further research is needed to address any existing gaps in screening and referral before repair.PMID:36882205 | DOI:10.1503/cjs.015321
Source: Canadian Journal of Surgery - March 7, 2023 Category: Surgery Authors: Garrett McDougall Samuel Jessula Claudia L Cote Matthew Cooper Min Lee Matthew Smith Patrick Casey Christine Herman Source Type: research

Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 7, 2023 Category: Surgery Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research

Effect of socioeconomic status on patients undergoing elective abdominal aortic aneurysm repair in a publicly funded health care system
CONCLUSION: Socioeconomic status does not appear to affect short- or long-term mortality after AAA repair in a publicly funded health care system. Further research is needed to address any existing gaps in screening and referral before repair.PMID:36882205 | PMC:PMC9998101 | DOI:10.1503/cjs.015321
Source: Canadian Journal of Surgery - March 7, 2023 Category: Surgery Authors: Garrett McDougall Samuel Jessula Claudia L Cote Matthew Cooper Min Lee Matthew Smith Patrick Casey Christine Herman Source Type: research

Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research