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Condition: Abdominal Aortic Aneurysm
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Total 234 results found since Jan 2013.
Role of DNA damage in the pathogenesis of atherosclerosis
J Cardiol. 2022 Sep 12:S0914-5087(22)00218-0. doi: 10.1016/j.jjcc.2022.08.010. Online ahead of print.ABSTRACTAtherosclerosis is a cause of coronary artery disease, abdominal aortic aneurysm, and stroke. The pathogenesis underlying atherosclerosis is complex but it is clear that inflammation plays a pivotal role. Inflammation in atherosclerosis is triggered by the recognition of intracellular contents released from damaged cells by pattern recognition receptors, and is therefore sterile and chronic. Because the DNA of these cells is damaged, cellular senescence is also involved in this inflammation. Here, we will discuss th...
Source: Journal of Cardiology - September 15, 2022 Category: Cardiology Authors: Mari Ishida Chiemi Sakai Takafumi Ishida Source Type: research
Systematic Review and Meta-analysis of Physician Modified Endografts for Treatment of Thoraco-Abdominal and Complex Abdominal Aortic Aneurysms
CONCLUSION: Physician modified fenestrated or branched grafts for endovascular aortic repair seems feasible and safe in the short-term follow-up. However, the quality of the available data is low which highlights the need for better and more accurate data regarding this technique.PMID:35483575 | DOI:10.1016/j.ejvs.2022.04.015
Source: PubMed: Eur J Vasc Endovasc ... - April 28, 2022 Category: Surgery Authors: Ryan Gouveia E Melo Carlota Fern ández Prendes Daniel Caldeira Jan Stana Barbara Rantner Anders Wanhainen Gustavo S Oderich Nikolaos Tsilimparis Source Type: research
Extent of mural thrombus is not associated with increased 5-year mortality following elective AAA repair
CONCLUSIONS: In our experience, the extent of mural thrombus in AAA does not influence long-term survival after elective repair. AAA repair may provide protection against circulating components of mural thrombus which have the potential to promote atherosclerotic-related adverse events. Patients with renal insufficiency and larger AAA have increased risk of mortality 5 years after elective repair.PMID:35331063 | DOI:10.1177/17085381211063282
Source: Vascular - March 25, 2022 Category: Surgery Authors: Bilal Siddiq Matthew Dejong Emily Decicco Tara Zielke Melissa D'Andrea Bernadette Aulivola Matthew Blecha Source Type: research
Athero-occlusive Disease Appears to be Associated with Slower Abdominal Aortic Aneurysm Growth: An Exploratory Analysis of the TEDY Trial
CONCLUSION: In an exploratory analysis of a selective cohort from the TEDY trial, AOD was associated with slower AAA growth. Validation of these findings in other cohorts is needed.PMID:35277322 | DOI:10.1016/j.ejvs.2021.12.038
Source: PubMed: Eur J Vasc Endovasc ... - March 12, 2022 Category: Surgery Authors: Evan O Matthews Joseph V Moxon Tejas P Singh Shivshankar Thanigaimani Rhondda E Jones Thomas C Gasser Robert Fitridge Jan H N Lindeman Ronald L Dalman Jonathan Golledge TEDY Investigators Source Type: research
Safety of Transcatheter Aortic Valve Replacement in Patients with Aortic Aneurysm: A Propensity-Matched Analysis
ConclusionsData from a large nationwide database demonstrated that patients with AA undergoing TAVR are associated with similar in-hospital outcomes compared with patients without AA.
Source: Cardiology and Therapy - March 6, 2022 Category: Cardiology Source Type: research
Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations RESEARCH
Functional consequences of genetic variation in the noncoding human genome are difficult to ascertain despite demonstrated associations to common, complex disease traits. To elucidate properties of functional noncoding SNPs with effects in human endothelial cells (ECs), we utilized our previous molecular quantitative trait locus (molQTL) analysis for transcription factor binding, chromatin accessibility, and H3K27 acetylation to nominate a set of likely functional noncoding SNPs. Together with information from genome-wide association studies (GWASs) for vascular disease traits, we tested the ability of 34,344 variants to p...
Source: Genome Research - March 3, 2022 Category: Genetics & Stem Cells Authors: Toropainen, A., Stolze, L. K., Örd, T., Whalen, M. B., Torrell, P. M., Link, V. M., Kaikkonen, M. U., Romanoski, C. E. Tags: RESEARCH Source Type: research
Fenestrated and branched endovascular repair for juxtarenal and thoracoabdominal aortic aneurysms: analysis of the first 100 cases
CONCLUSIONS: This study confirms that fenestrated and branched endovascular repair is a safe and feasible treatment for juxtarenal and thoracoabdominal aortic aneurysms with acceptable complication rates. The perioperative cardiac mortality highlights the importance of pre-operative risk assessment and patient selection.PMID:35142459 | DOI:10.23736/S0021-9509.22.11964-6
Source: The Journal of Cardiovascular Surgery - February 10, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Gilles Uijtterhaegen Karen VAN Langenhove Nathalie Moreels Isabelle VAN Herzeele Frank Vermassen Source Type: research
