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Condition: Abdominal Aortic Aneurysm

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Total 234 results found since Jan 2013.

Statins and subarachnoid hemorrhage in Medicare patients with unruptured cerebral aneurysms
ConclusionsStatin use by patients with unruptured cerebral aneurysms was not associated with subarachnoid hemorrhage risk. Given the prior animal experimental studies demonstrating a protective effect, further prospective studies are needed to investigate the potential relationship.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Kimon Bekelis, Jeremy Smith, Weiping Zhou, Todd A. MacKenzie, David W. Roberts, Jonathan Skinner, Nancy E. Morden Tags: Research Source Type: research

A randomized controlled trial on the effects of goal directed therapy on the inflammatory response open abdominal aortic aneurysm repair
IntroductionGoal directed therapy (GDT) has been shown in numerous studies to decrease perioperative morbidity and morality. The mechanism of benefit of GDT however, has not been clearly elucidated. Targeted resuscitation of the vascular endothelium with GDT might alter the postoperative inflammatory response and be responsible for the decreased complications with this therapy. Methods: This trial was registered at ClinicalTrials.gov as NCT01681251. Forty patients undergoing elective open repair of their abdominal aortic aneurysm (AAA), 18 years of age and older were randomized to an interventional arm with GDT targeting s...
Source: Critical Care - June 10, 2015 Category: Intensive Care Authors: Duane FunkKent HayGlassJoshua KoulackGreg HardingApril BoydRyan Brinkman Source Type: research

Systematic review of cardiovascular disease and cardiovascular death in patients with a small abdominal aortic aneurysm
ConclusionThe risk of cardiovascular death in patients with a small AAA is high and increases by approximately 3 per cent each year after diagnosis. Patients with a small AAA have a high prevalence of cardiovascular disease. Patients a small AAA should be considered for lifestyle modifications and secondary cardiovascular protection.
Source: British Journal of Surgery - May 14, 2015 Category: Surgery Authors: M. F. Bath, V. J. Gokani, D. A. Sidloff, L. R. Jones, E. Choke, R. D. Sayers, M. J. Bown Tags: Systematic review Source Type: research

Abstract 250: Real-world Rates and Costs of Heart Failure Events Among Patients with Hyperlipidemia Session Title: Poster Session II
Conclusions: The rate and recurrence of heart failure among hyperlipidemic patients is very high and the long term healthcare costs substantial in this real-world 2-year study.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Fox, K. M., Punekar, R. S., Richhariya, A., Fisher, M. D., Gandra, S. R., Cziraky, M. J., Toth, P. P. Tags: Session Title: Poster Session II Source Type: research

Abstract 263: Incidence of Recurrent Cardiovascular Events and Disease Burden Among High-Risk Patients with Hyperlipidemia Session Title: Poster Session II
Conclusions: CV event-related risk and long-term costs are significantly greater among high-risk patients with shorter time intervals between recurrent CV events. Underutilization of LLTs in these patients highlights the need for improving clinical management and treatment options for these patients.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Punekar, R. S., Fox, K. M., Richhariya, A., Fisher, M. D., Gandra, S. R., Cziraky, M. J., Toth, P. P. Tags: Session Title: Poster Session II Source Type: research

Recent thoraco-abdominal aortic repair outcomes using moderate-to-deep hypothermia combined with targeted reconstruction of the Adamkiewicz artery
CONCLUSIONS Moderate-to-deep hypothermia combined with targeted reconstruction of the AKA provided satisfactory outcomes with thoraco-abdominal aortic repair, particularly for spinal cord protection.
Source: Interactive CardioVascular and Thoracic Surgery - April 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tanaka, H., Minatoya, K., Sasaki, H., Seike, Y., Itonaga, T., Oda, T., Kobayashi, J. Tags: Pericardium Adult Cardiac Source Type: research

The importance of and current trends in the endovascular program – A single center experience
Conclusion In the AAA group, the percentage of EVAR stabilized during the last 5 years at about 32% of the total number of treated patients. Given the excellent results of open carotid surgery and the unconvincing results of stenting trials, we consider open carotid surgery to be better than carotid artery primary stenting.
Source: Cor et Vasa - April 13, 2015 Category: Cardiology Source Type: research

Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis
Publication date: Available online 26 February 2015 Source:The Lancet Diabetes & Endocrinology Background To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 (IL-1) inhibition, we studied genetic variants that produce inhibition of IL-1, a master regulator of inflammation. Methods We created a genetic score combining the effects of alleles of two common variants (rs6743376 and rs1542176) that are located upstream of IL1RN, the gene encoding the IL-1 receptor antagonist (IL-1Ra; an endogenous inhibitor of both IL-1α and IL-1β); both alleles increase soluble IL-1Ra ...
Source: The Lancet Diabetes and Endocrinology - February 26, 2015 Category: Endocrinology Source Type: research

Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1 937 360 people in England: lifetime risks and implications for risk prediction
Conclusions The heterogeneous associations of smoking with different CVD presentations suggests different underlying mechanisms and have important implications for research, clinical screening and risk prediction.
Source: International Journal of Epidemiology - February 22, 2015 Category: Epidemiology Authors: Pujades-Rodriguez, M., George, J., Shah, A. D., Rapsomaniki, E., Denaxas, S., West, R., Smeeth, L., Timmis, A., Hemingway, H. Tags: Cardiovascular Disease and Cardiovascular Risk Factors Source Type: research

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people
This study is registered at ClinicalTrials.gov (NCT01804439). Findings Our cohort consisted of 1 921 260 individuals, of whom 1 887 062 (98·2%) did not have diabetes and 34 198 (1·8%) had type 2 diabetes. We observed 113 638 first presentations of cardiovascular disease during a median follow-up of 5·5 years (IQR 2·1–10·1). Of people with type 2 diabetes, 6137 (17·9%) had a first cardiovascular presentation, the most common of which were peripheral arterial disease (reported in 992 [16·2%] of 6137 patients) and heart failure (866 [14·1%] of 6137 patients). Type 2 diabetes was positively associated wi...
Source: The Lancet Diabetes and Endocrinology - December 5, 2014 Category: Endocrinology Source Type: research

Report of the 2013 data of the Hungarian Vascular Registry.
CONCLUSIONS: Registers have been proved to be useful in countries where they are used regularly for decision making. Our best common interest is to maintain a well-established national database. PMID: 25500643 [PubMed - in process]
Source: Magyar Sebeszet - December 1, 2014 Category: Surgery Authors: Szeberin Z, Hidi L, Kováts T, Menyhei G Tags: Magy Seb Source Type: research

Medical management of abdominal aortic aneurysms.
Abstract Abdominal aortic aneurysms (AAA) are the most common arterial aneurysms. Endovascular or open surgical aneurysm repair is indicated in patients with large AAA ≥ 5.5 cm in diameter as this prevents aneurysm rupture. The presence even of small AAAs not in need of immediate repair is associated with a very high cardiovascular risk including myocardial infarction, stroke or cardiovascular death. This risk by far exceeds the risk of aneurysm rupture. These patients therefore should be considered as high-risk patients and receive optimal medical treatment and life-style modificiation of their cardiovascular r...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 27, 2014 Category: Surgery Authors: Weiss N, Rodionov RN, Mahlmann A Tags: Vasa Source Type: research

Embolic complications after endovascular repair of abdominal aortic aneurysms
Conclusions The presence of a shaggy aorta and a history of smoking are independent predictors of embolic complications associated with EVAR.
Source: Surgery Today - September 25, 2014 Category: Surgery Source Type: research

210 * contemporary approach of thoraco-abdominal aortic repair using moderate to deep hypothermia combined with target reconstruction of the adamkiewicz artery
Conclusion: Moderate to deep hypothermia combined with target reconstruction of the Adamkiewicz artery brings satisfactory outcomes in thoraco-abdominal aortic repair, especially for spinal cord protection.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Tanaka, H., Minatoya, K., Sasaki, H., Oda, T., Itonaga, T., Kobayashi, J. Tags: Thoraco-abdominal aortic repair reloaded Source Type: research

Open versus endovascular repair of abdominal aortic aneurysm: Incidence of cardiovascular events in 632 patients in a department of defense cohort over 6-year follow-up.
CONCLUSION: EVAR was associated with lower 30-day mortality rates; however, this benefit was not sustained in longer-term follow-up. There is no difference in the rates of stroke, myocardial infarction, or cardiac arrhythmia at 30 days or in long-term follow-up. PMID: 25134851 [PubMed - as supplied by publisher]
Source: Vascular - August 18, 2014 Category: Surgery Authors: Thomas D, Anderson D, Hulten E, McRae F, Ellis S, Malik JA, Villines TC, Slim AM Tags: Vascular Source Type: research