Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms [Genetics]

Conclusions
Although there was no evidence for polygenic overlap between IAs, AAAs, and TAAs, we found nominally significant effects of two established risk loci for IAs and TAAs in AAAs. These two loci will require further replication.

Source: JAHA:Journal of the American Heart Association - July 13, 2016 Category: Cardiology Authors: van t Hof, F. N. G., Ruigrok, Y. M., Lee, C. H., Ripke, S., Anderson, G., de Andrade, M., Baas, A. F., Blankensteijn, J. D., Böttinger, E. P., Bown, M. J., Broderick, J., Bijlenga, P., Carrell, D. S., Crawford, D. C., Crosslin, D. R., Ebeling, C., Tags: Inflammation, Vascular Biology, Ischemic Stroke Genetics Source Type: research