Chronic venous insufficiency and venous microangiopathy: management with compression and Pycnogenol ®.
Chronic venous insufficiency and venous microangiopathy: management with compression and Pycnogenol®. Minerva Cardioangiol. 2019 Aug;67(4):280-287 Authors: Cesarone MR, Belcaro G, Agus GB, Ippolito E, Dugall M, Hosoi M, Corsi M, Cotellese R, Feragalli B, Scipione C, Scipione V, Maione C Abstract BACKGROUND: The aim of this prospective supplement summer registry study was to evaluate the efficacy of Pycnogenol® in controlling symptoms of chronic venous insufficiency (CVI) and microcirculatory parameters: venous hypertension and microangiopathy. Pycnogenol® (Horphag Research) is the standardi...
Source: Minerva Cardioangiologica - July 28, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Early functional and structural changes of the left atrium in a patient with trastuzumab: related cardiotoxicity.
Authors: Cerrito LF, Bergamini C, Dolci G, Fiorio E, Ribichini FL Abstract PMID: 31347821 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - July 28, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Use of DOACs in real-world challenging settings: a Delphi Consensus from Italian cardiologists.
CONCLUSIONS: DOACs should represent the first-line anticoagulation therapy in non-valvular AF patients in the majority of challenging settings, underexplored by literature. Caution in their prescription is needed in case of severe renal impairment. Dose choice should follow the SmPC, although this is matter of debate in borderline patients. PMID: 31343145 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - July 27, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Helicobacter pylori and cardiovascular disease: update 2019.
Authors: Mladenova I Abstract Many studies have been performed concerning the potential role of Helicobacter pylori (H. pylori) in different extra-gastric diseases. Ischemic heart disease (IHD) remains the leading cause of mortality in developed countries. The traditional cardiovascular risk factors could not predict all cases of IHD. Hence, the scientists explore other potential etiologic factors, especially infections. H. pylori infection has been suspected to have a role in the pathogenesis of atherosclerosis. However, after 25 years from the first description, the role of the bacterium in the pathogenesis of IH...
Source: Minerva Cardioangiologica - July 27, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Exercise and atrial fibrillation: how health turns harm, and how to turn it back.
Authors: Tirapu L, San Antonio R, Tolosana JM, Roca-Luque I, Mont L, Guasch E Abstract Exercise is, together with diet, a powerful health-promoting habit. However, an association of intense physical activity with the onset of atrial and ventricular arrhythmias, and sudden death has been described. Although initially questioned, the atrial pro-arrhythmic role of endurance physical activity is now well accepted in the scientific community. Atrial fibrillation is common among endurance athletes, being a source of morbidity in otherwise healthy young and middle-aged individuals. The mechanisms for its development are s...
Source: Minerva Cardioangiologica - July 27, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Implications of the new 2017 American College of Cardiology/American Aeart Association Guidelines for Hypertension.
Authors: Aronow WS Abstract Automated validated devices should be used for measuring blood pressure (BP). The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) hypertension guidelines recommend that a systolic BP between 120-129 mm Hg with a diastolic BP less than 80 mm Hg should be treated with lifestyle measures. These guidelines recommend treatment with lifestyle measures plus BP lowering drugs for secondary prevention of cardiovascular events in persons with clinical cardiovascular disease and an average systolic BP of ≥130 mm Hg or an average diastolic BP ≥ 80 mm Hg. These guidel...
Source: Minerva Cardioangiologica - June 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Non vitamin K oral anticoagulants versus antiplatelets in embolic stroke of undetermined source: most updated evidence.
Authors: Chatterjee S, Dubey S, Lahiri D, Ray BK Abstract Recent trial data have expanded the horizons of newer indications of non vitamin K oral anticoagulants (NOAC). Most recently they are being evaluated for use in embolic stroke of undetermined source (ESUS). ESUS are particularly known for their recurrences. So, identifying the causes and treating those etiological factors are the keys to secondary prevention of ESUS. Although traditional experts still opine for the use of antiplatelets for secondary prevention of ESUS as for other causes of embolic stroke, there are still room for improvement in delivery of ...
Source: Minerva Cardioangiologica - June 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Relationships between left ventricular geometry (sphericity index) and remodeling in dilated cardiomyopathy.
Authors: Dziewięcka E, Wiśniowska-Śmiałek S, Khachatryan L, Karabinowska A, Szymonowicz M, Podolec P, Rubiś P Abstract BACKGROUND: Since left ventricular reverse remodeling (LVRR) and sphericity index (SI) are correlated with DCM patients' survival, we attempted to establish the relationship between LVRR, SI and left ventricle (LV) dimensions. METHODS: In 70 DCM patients, we measured EF, LV transverse (sLVd) and longitudinal (lLVd) diameters at hospital admission, then after 3 and 12 months. SI was assessed thus: SI=sLVd/lLVd. RESULTS: LVRR was present in 32 patients (52%). SI measurements were similar...
Source: Minerva Cardioangiologica - May 24, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Ablation, rate or rhythm control strategies for patients with atrial fibrillation: how do they affect mid-term clinical outcomes? A retrospective cohort study.
CONCLUSIONS: AF ablation is able to decrease the arrhythmic episodes but does not offer a statistically significant protection against the composite of death, disabling stroke, severe bleeding and cardiac arrest In the mid-term follow-up. PMID: 31115243 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - May 24, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Effectiveness of the ECG method in the correct positioning of PICC type central venous catheters in patients with atrial fibrillation.
Authors: Albertini F, Struglia M, Faraone V, Fioravanti R, Boursier Niutta S Abstract The peripherally inserted central catheters (PICCs) are third generation silicone or polyurethane catheters, used as venous accesses for long- and medium-term care, and recommended in therapies that require venous access for more than six days. Current implantation methods recommend the radiological method, using standard chest RX in antero-posterior projection, as a method of assessing the correct positioning of the catheter tip. The observational study evaluated the effectiveness in terms of reliability of the intracavitary tip ...
Source: Minerva Cardioangiologica - May 24, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Left ventricular dysfunction and short and long-term mortality in patient with st-elevation myocardial infarction who underwent primary percutaneous coronary intervention: a study from Thailand.
Authors: Kewcharoen J, Kittipibul V, Suttirut P, Lertsuwunseri V, Athisakul S, Chaipromprasit J, Buddhari W, Udayachalerm W, Srimahachota S, Ariyachaipanich A Abstract PMID: 30991793 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - April 18, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Recurrent retinal vein thrombosis: prevention with Aspirin, Pycnogenol ®, ticlopidine, or sulodexide.
Recurrent retinal vein thrombosis: prevention with Aspirin, Pycnogenol®, ticlopidine, or sulodexide. Minerva Cardioangiol. 2019 Apr;67(2):109-114 Authors: Belcaro G, Dugall M, Bradford HD, Cesarone MR, Feragalli B, Gizzi C, Cotellese R, Hu S, Rodriguez P, Hosoi M Abstract BACKGROUND: The aim of this study is to evaluate the use of Aspirin, Pycnogenol®, ticlopidine, and sulodexide to reduce the incidence of new RTV (retinal vein thrombosis) after a first episode. Pycnogenol® is an anti-inflammatory, anti-edema, mild antiplatelet-antithrombotic agent. METHODS: The registry study evaluated...
Source: Minerva Cardioangiologica - April 11, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Cardiogenic shock due to coronary fistula: a complex phenomenon.
Authors: Manfredonia L, Genuardi L, Marano R, Rebuzzi AG, Buffon A, Burzotta F Abstract PMID: 30964247 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - April 11, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Validation of a new score for outcome prediction in patients with heart failure with reduced ejection fraction.
Authors: Loiacono F, Fragasso G, Calori G, Alberti L, Marinosci G, Salerno A, Margonato A Abstract BACKGROUND: Most models for outcome prediction in heart failure are under-utilized because complex or including non-routine clinical use variables. We aimed to develop a prognostic score for patients with stable heart failure, including only easily obtainable parameters. METHODS: In 376 outpatients with heart failure (ejection fraction ≤40%), twelve variables were individually correlated with 5-year mortality. Those resulted significant predictors of cardiac and overall mortality were used to obtain a risk scor...
Source: Minerva Cardioangiologica - March 29, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Baseline indicators of coronary artery disease burden in patients with non-ST-segment elevation acute coronary syndrome.
Authors: Stepien K, Nowak K, Skorek P, Baravik V, Kozynacka A, Nessler J, Zalewski J Abstract BACKGROUND: We sought to investigate whether baseline characteristics of patients with non-ST-segment elevation acute coronary syndrome (NSTEACS) may predict their coronary artery disease (CAD) burden. METHODS: Baseline clinical, ECG and laboratory data were compared with angiographic findings of 693 consecutive NSTEACS patients. According to the angiography result all patients were assigned to one of the three groups with: significant stenosis of left main and/or three-vessel CAD (LM-3VD, n=114), single- or two-vessel...
Source: Minerva Cardioangiologica - March 29, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Prognostic role of Pro-BNP levels in left ventricular hypertrabeculation/noncompaction and neuromuscular disorders: results of a pilot study.
Authors: Malli N, Wilfinger-Lutz N, Krugluger W, Stöllberger C, Winkler-Dworak M, Finsterer J Abstract PMID: 30919605 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 29, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Hybrid ablation for atrial fibrillation: the importance of achieving transmurality and lesion validation.
Authors: Hassan SM, Hong K, Rosati F, Glover B, Redfearn D, Enriquez A, Bisleri G Abstract Therapeutic ablation for atrial fibrillation (AF) has evolved significantly with progressive advancements in technology and surgical instruments. With the goal of minimizing surgical morbidity while maintaining the benefits of the traditional Cox-Maze procedure, surgical ablation for AF has undergone significant modifications. Most recently, an increased understanding of substrate complexity, predominantly in patients with persistent or long-standing persistent AF, has led to the development of a synergistic hybrid approach. ...
Source: Minerva Cardioangiologica - March 29, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Management of aspirin intolerance in patients undergoing percutaneous coronary intervention: the role of mono-antiplatelet therapy. A retrospective, multicenter, study.
CONCLUSIONS: Our study evaluating patients with ACS or stable CAD undergoing PCI and treated with mono anti-platelet therapy with P2Y12 inhibitors due to aspirin intolerance shows a 25% incidence of POCE at one year. Further studies with adequate sample size are required to evaluate the efficacy and safety of mono anti-platelet therapy in this clinical scenario. PMID: 30895761 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Antihypertensive effect of sacubitril/valsartan: a meta-analysis.
Authors: De Vecchis R, Ariano C, Soreca S Abstract INTRODUCTION: Sacubitril/valsartan used as an antihypertensive agent has not yet been completely assessed as regards its efficacy and safety. Thus, to investigate them in elderly hypertensive patients, a meta-analysis has been performed. EVIDENCE ACQUISITION: The meta-analysis incorporated only randomized controlled trials(RCTs) in which sacubitril/valsartan was compared with a reference drug. The mean reductions in systolic blood pressure( msSBP) and diastolic blood pressure( msDBP) in the sitting position as well as the mean reductions in ambulatory systolic ...
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

ECG in noonan syndrome: beyond the "normal abnormalities".
ECG in noonan syndrome: beyond the "normal abnormalities". Minerva Cardioangiol. 2019 Mar 18;: Authors: Mazza GA, Banaudi E, Ferrero GB, Baldassarre G, Agnoletti G Abstract PMID: 30895763 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Everolimus-eluting bioresorbable vascular scaffolds: learning from the past to improve the future.
Authors: Mahtta D, Elgendy IY Abstract Bioresorbable vascular scaffolds (BVS) were developed to overcome the long-term limitations of metallic drug-eluting stents (DES). Shortcomings of DES include their permanent metallic cage which prevents normal coronary vasomotion, vascular remodeling, precludes future bypass grafting, and create a nidus for very late stent thrombosis. With its transient scaffold which provides early mechanical support and subsequently resorbs thereby restoring physiologic properties and architecture of the vasculature, BVS offers a promising development within the field of interventional card...
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Novel ultra-long (48 mm) everolimus-eluting stent for diffusely disease coronary vessels.
CONCLUSIONS: The present real-world experience shows promising clinical results with the use of ultra-long stents in order to limit the need of stents overlaps in patients with diffuse coronary disease undergoing PCI. PMID: 30895769 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Intravascular ultrasound-guided drug-eluting stent implantation.
Authors: Shlofmitz E, Kuku KO, Waksman R, Garcia-Garcia HM Abstract Intravascular ultrasound (IVUS) enhances diagnostic assessment with identification and characterization of plaque morphology. Determination of predominant plaque morphology prior to percutaneous coronary intervention can guide optimal treatment strategy. The transducers used with IVUS catheters include solid-state, phased array systems that have multiple stationary transducers, or rotational, mechanical IVUS systems that have a single transducer that rotates on a driveshaft. Real-time online analysis with IVUS allows determination of lumen and vess...
Source: Minerva Cardioangiologica - March 9, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Cardiotrophin as a prognostic factor in heart failure.
Authors: Qawoq HD, Sobczak M, Szcześniak P, Pagórek P, Miśkowiec D, Wierzbowska Drabik K, Chrzanowski Ł, Kasprzak JD Abstract PMID: 30724267 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Incidence of infective endocarditis before and after the guideline modification regarding a more restrictive use of prophylactic antibiotics therapy in the United States of America and Europe.
Authors: Keller K, Hobohm L, Munzel T, Ostad MA Abstract Infective endocarditis (IE) is a potentially life-threatening disease. Regardless the improvements in IE management, it remains associated with high mortality and severe complications. Staphylococci and streptococci account for 80% of all IE cases. Prevention of IE by appropriate administration of antibiotics before procedures with potential bacteremia in selected patients is recommended according to recent and current guidelines. However, recent studies, have questioned the efficacy of antimicrobial prophylaxis in special situations and in some patient-group...
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Long-term rhythm monitoring with an implantable loop recorder in patients after the first clinical atrial fibrillation episode. Towards an individualized management.
Authors: Papakonstantinou PE, Simantirakis EN Abstract Although atrial fibrillation (AF) is an arrhythmia with a variable clinical profile (symptomatic and asymptomatic episodes), the first symptomatic episode leads to its initial diagnosis in most cases. Nowadays, continuous and remote long- term cardiac rhythm monitoring is feasible by the use of implantable loop recorders. The data concerning the AF recurrences and progression after the first ECG- documented clinical AF episode demonstrates that a high percentage of patients may not suffer any other AF recurrence, or may present a low recurrence rate of the arrh...
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

The prognostic value of mean platelet volume to platelet count ratio in older patients with non-ST elevation acute coronary syndrome receiving primary percutaneous coronary intervention: a retrospective study.
Authors: Sun X, Li H, Zhang Y, He F, Lu C Abstract BACKGROUND: To investigate the value of the mean platelet volume to platelet count (MPV/P) ratio for predicting in-hospital and long-term cardiac mortality in older non-ST elevation- Acute coronary syndrome (NSTE-ACS) patients after primary percutaneous coronary intervention (PCI). METHODS: We retrospectively reviewed 452 older NSTE-ACS patients who received primary PCI. The patients were divided into two groups based on MPV/P ratios: high MPV/P group (n = 150) defined as a value in the third tertile (> 0.056628) and low MPV/P group (n = 302) in the lower tw...
Source: Minerva Cardioangiologica - January 11, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Clinical relevance of myocardial bridging detected by coronary CT angiography in patients with atypical chest pain.
Authors: La Grutta L, Malagò R, Toia P, Tabacco G, Smeraldi T, Albano D, Finetto G, Poletti M, Tavella D, Grassedonio E, Galia M, Cademartiri F, Pozzi Mucelli R, Midiri M Abstract PMID: 30604949 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - January 4, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Novel transcatheter therapies for treating tricuspid regurgitation.
Authors: Miura M, Maisano F, Zuber M, Gavazzoni M, Cuevas O, Lin SI, Ho EC, Pozzoli A, Taramasso M Abstract Until recently, tricuspid valve (TV) disease has been relatively neglected for a long time, but recently tricuspid regurgitation (TR) has attracted attention. Although the prognosis of patients with these disorders is poor, the high mortality and morbidity associated with TV surgery have resulted in many patients not receiving surgical therapy. Current guidelines recommend that TV surgery should be considered in patients with severe TR who are symptomatic or have progressive right ventricle (RV) dilatation or...
Source: Minerva Cardioangiologica - December 1, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Tricuspid regurgitation: from physiopathology to transcatheter interventions.
Authors: Latib A, Colombo A, Regazzoli D Abstract PMID: 30468061 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Update on cardiac implantable electronic devices: from the injectable loop recorder to the leadless pacemaker, to the subcutaneous defibrillator.
Authors: Santini M, Santini L, Di Fusco SA Abstract A very fast-paced improvement of technology in the field of cardiac implantable devices has been observed in the last ten years. The aim of this review is to highlight the most important innovations which have been recently introduced in this field, such as the leadless pacemaker (a heart stimulator without intracardiac leads), the subcutaneous defibrillator (a completely extracardiac defibrillator device), the injectable loop recorder (a miniaturized subcutaneous continuous echocardiographic monitor provided by alarms and telephonic transmission) and many other n...
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Left ventricular rotational abnormalities in chloroquine-induced cardiomyopathy (from the MAGYAR-Path Study).
Authors: Nemes A, Nagy V, Domsik P, Kalapos A, Kormányos Á, Havasi K, Forster T Abstract PMID: 30468063 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

All-in-One procedure: simultaneous percutaneous treatment of aortic and mitral valve disease in inoperable patient.
Authors: Červinka P, Cihlář F, Vojtíšek P, Červinková M Abstract PMID: 30468362 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Efficacy of Pycnogenol ® supplementation in remission phases of Sjögren syndrome.
Efficacy of Pycnogenol® supplementation in remission phases of Sjögren syndrome. Minerva Cardioangiol. 2018 Oct;66(5):543-546 Authors: Luzzi R, Belcaro G, Hu S, Feragalli B, Hosoi M, Dugall M, Ledda A Abstract BACKGROUND: The aim of this study was to evaluate the effects of Pycnogenol® supplementation in otherwise healthy subjects with Sjögren syndrome (SS) in a remission phase, who experienced persisting symptoms impairing their quality of life. METHODS: The control group receiving only standard treatment was composed of 14 subjects, the supplement group included 16 subjects who ...
Source: Minerva Cardioangiologica - October 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Effects of dronedarone on all-cause mortality and on cardiovascular events in patients treated for atrial fibrillation. A meta analysis of RCTs.
CONCLUSIONS: In our meta-analysis, dronedarone did not provide any significant benefit with regard to all-cause mortality and major cardiovascular events, as well as regarding the risk of worsening heart failure. Sensitivity analyses then showed that the exclusion of a study ,namely ATHENA study, caused a shift in the overall odds ratio, so as to convert the dronedarone use to the ominous role of predictor of higher mortality, worse cardiovascular morbidity and increased risk of worsening heart failure. Thus, dronedarone should be used with caution as second- line medication and exclusively for the secondary prevention of ...
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Comparative analysis of cardiac cycle length during exercise in healthy people and cardiac patients.
Authors: Galindo-Canales M, Rojo-González JJ, Barriopedro MI, Ramos-Álvarez JJ, Calderón-Montero FJ PMID: 30260142 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Electrocardiographic conduction and repolarization markers associated with sudden cardiac death: moving along the ECG waveform.
Authors: Reynard JT, Oshodi OM, Lai J, Lai R, Bazoukis G, Fragakis N, Letsas KP, Korantzopoulos P, Liu FZ, Liu T, Xia Y, Tse G, Li KH Abstract The QT interval along with its heart rate corrected form (QTc) are well- established ECG markers that have been found to be associated with malignant ventricular arrhythmogenesis. However, extensive pre-clinical and clinical investigations over the years have allowed for novel clinical ECG markers to be generated as predictors of arrhythmogenesis and sudden cardiac death. Repolarization markers include the older QTc, QT dispersion and newer Tpeak - Tend intervals, (Tpeak - T...
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Transcatheter aortic valve replacement in low risk patients.
Authors: Junquera L, Ferreira-Neto A, Guimaraes L, Asmarats L, Del Val D, Wintzer-Wehekind J, Muntané-Carol G, Freitas-Ferraz A, Rodés-Cabau J Abstract Transcatheter aortic valve replacement (TAVR) is a relatively new technology that has grown exponentially over the past decade. Although it was initially restricted to elderly patients at very high or prohibitive surgical risk, it is currently being evaluated as a treatment option in younger and lower risk patients. The increasing experience of the Heart Teams, along with the continued refinement of transcatheter valve technology has resulted in TAVR a...
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Cell therapy and left ventricular restoration for ischemic cardiomyopathy: long-term results of a perspective, randomized study.
CONCLUSIONS: Patients affected by ischemic cardiomyopathy have a favourable outcome after SVR.A higher reduction of LVEDV and LVESV assessed by CT-Scan evaluation in patients receiving cell therapy, when compared to control group, encourages the evolution and refinement of myocardial regenerative therapy added to SVR. PMID: 30260145 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

A glimpse into upcoming TAVI era: new is coming.
Authors: Kleczynski P PMID: 30260146 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 29, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Deferred stenting for acute myocardial infarction of late admission.
Authors: Chen H, Zhu J, Zhuang Y PMID: 30226029 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

A novel approach to quantification of aortic valve calcifications in patients undergoing transcatheter aortic valve implantation.
CONCLUSIONS: Multiplane AVC quantitative evaluation provided details on total calcium amount, pattern and distribution in aortic valve. Established AVC parameters allowed better visualization of an operating area and prediction of PVL after TAVI. PMID: 30226030 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Degeneration of prosthesis after transcatheter aortic valve implantation.
This article review will go through the current evidence of TAV durability, describing the types of failure and strategies of treatment. PMID: 30226031 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Interaction study between antiplatelet agents, anticoagulants, diabetic therapy and a novel delivery form of quercetin.
CONCLUSIONS: Quercetin Phytosome® does not alter the antiplatelet activity of the most common antiplatelet agents, has no impact on the INR values in stable patients treated with warfarin or dabigatran, and does not influence the metabolic control of diabetic patient treated with metformin. PMID: 30226032 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - September 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Prospective registry on cerebral oximetry-guided transcarotid TAVI in patients with moderate-high risk aortic stenosis.
Authors: Hudziak D, Nowak AM, Gocoł R, Parma R, Ciosek J, Ochała A, Deja M, Wojakowski W Abstract AIM OF STUDY: The aim of the study was to assess safety TAVI procedure through the common carotid artery in high-vascular-risk patients. METHODS: The approach was selected by a multidisciplinary (cardiologists and cardiac surgeons) heart team after analyzing preoperative coronary angiography, TTE and MSCT of the peripheral arteries. Patients with the following conditions were qualified to the transcarotid access: severe PAD (stenotic, heavily calcified), tortuous or small diameter
Source: Minerva Cardioangiologica - September 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Could mechanical thrombectomy replace thrombolysis in the treatment of acute and subacute limb ischemia?
Authors: Stanek F, Ouhrabkova R, Prochazka D Abstract Acute limb ischemia is a vascular emergency defined as a sudden decrease in limb perfusion associated with a risk of loss of viability of the affected extremity. Surgical treatment (Fogarty thromboembolectomy) is indicated only in suprainguinal occlusions. Other cases of acute and subacute limb ischemia should be managed percutaneously. Catheter-based treatment involves local thrombolysis and percutaneous mechanical thrombectomy (PMT). There are several devices in use for PMT; of them, the Rotarex system appears to be the most useful. There are no randomized stu...
Source: Minerva Cardioangiologica - September 1, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Neuroprotective measures throughout the TAVI pathway.
Authors: Shiyoich A, Kornowski R Abstract Aortic stenosis (AS) is the most common clinical valvular heart disorder that warrants active treatment. Symptomatic and severe AS is associated with increased morbidity and mortality if left untouched. Transcatheter aortic valve implantation (TAVI) is an innovative therapeutic modality approved initially for patients with prohibitive surgical risk and subsequently became a mainstream practice and the preferred treatment modality for many patients with severe AS at high and moderate surgical risk. Consistently global TAVI volumes have increased and indications continue to w...
Source: Minerva Cardioangiologica - July 19, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Beh çet syndrome: effects of Pycnogenol® supplementation during regression phases.
Behçet syndrome: effects of Pycnogenol® supplementation during regression phases. Minerva Cardioangiol. 2018 Aug;66(4):386-390 Authors: Hu S, Belcaro G, Ledda A, Corsi M, Cotellese R, Feragalli B, Hosoi M, Dugall M, Torino-Rodriguez P, Cesarone MR Abstract BACKGROUND: The aim of this comparative registry study was to evaluate the supplementation with Pycnogenol® in subjects with Behçet syndrome (BS) with symptoms impairing their quality of life despite being in a remitting phase of the disease. METHODS: Thirty-four patients with a confirmed diagnosis of BS were divided into th...
Source: Minerva Cardioangiologica - July 7, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

An overview on STEMI.
Authors: Menozzi A PMID: 29975021 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - July 7, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Percutaneous tricuspid annuloplasty.
Authors: Donatelle M, Lim DS Abstract Severe tricuspid regurgitation (TR) is a common problem, affecting approximately 1.6 million Americans, with the majority (85%) of TR being functional in nature. When left untreated, TR is associated with progressive right-sided heart failure, with a poor prognosis entailing high morbidity and mortality. Surgical repair is still the gold standard for TR, but only a small proportion of patients undergo surgical repair leaving a high clinical demand for alternatives to conventional surgery. Percutaneous repair and replacement of cardiac valves have exponentially advanced in the p...
Source: Minerva Cardioangiologica - July 4, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research