Filtered By:
Specialty: General Medicine
This page shows you your search results in order of date.
Order by Relevance | Date
Total 380 results found since Jan 2013.
Transcription Factor JunB Suppresses Hepatitis C Virus Replication
Kobe J Med Sci. 2023 Aug 31;69(3):E86-E95.ABSTRACTWe previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK is known to have numerous target genes, including JunB, a member of activator protein-1 transcription factor family. However, the roles of JunB in the HCV life cycle and HCV-associated pathogenesis remain unclear. To clarify a physiological role of JunB in HCV infe...
Source: Kobe J Med Sci - September 4, 2023 Category: General Medicine Authors: Adi Ariffianto Lin Deng Saki Harada Yujiao Liang Chieko Matsui Takayuki Abe Ikuo Shoji Source Type: research
SPTBN2 regulates endometroid ovarian cancer cell proliferation, invasion and migration via ITGB4 ‑mediated focal adhesion and ECM receptor signalling pathway
Exp Ther Med. 2023 Apr 24;25(6):277. doi: 10.3892/etm.2023.11977. eCollection 2023 Jun.ABSTRACTOvarian cancer is as a major contributor to gynaecologic death globally. The present study aimed to investigate the regulatory role of spectrin β non-erythrocytic 2 gene (SPTBN2) in endometroid ovarian cancer and its mechanism of action. According to the Gene Expression Profiling Interactive Analysis (GEPIA) database, SPTBN2 expression is elevated in ovarian cancer tissues and higher SPTBN2 expression indicated a worse prognosis. The present study assessed SPTBN2 mRNA and protein expression levels by reverse transcription-quanti...
Source: Experimental and Therapeutic Medicine - May 19, 2023 Category: General Medicine Authors: La Yang Yuanyuan Gu Source Type: research
