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Cancer: Gastric (Stomach) Cancer
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Total 1410 results found since Jan 2013.
SNHG16 lncRNAs are overexpressed and may be oncogenic in human gastric cancer by regulating cell cycle progression
Neoplasma. 2021 Dec 6:210518N680. doi: 10.4149/neo_2021_210518N680. Online ahead of print.ABSTRACTThe small nucleolar RNA host gene 16 (SNHG16) has recently been shown to be a putative oncogene in gastric cancer (GC) and other cancer types, but how its four lncRNA variants are expressed in any physiological and pathological situation remains unknown. To investigate the expression and function of the four lncRNA variants of SNHG16, mainly the variant 1, in GC, we performed quantitative PCR to determine the RNA levels of the four variants in 60 GC tissue samples and several cell lines. We also studied how knocking down of SN...
Source: Neoplasma - December 9, 2021 Category: Cancer & Oncology Authors: Juan-Juan Zhao Juan-Juan Liu Yun-Yuan Zhang Ying Xia Hong Du Zhi-Qiang Yan Chun-Huan Zhou Wan-Song Xia Lucas Zellmer De-Zhong Joshua Liao Si-Xi Wei Hai Huang Source Type: research
TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor- β Signaling Pathway
CONCLUSIONS: TRPV2 appeared to promote tumor migration and invasion via the TGF-β signaling pathway, and the strong expression of TRPV2 was associated with a worse prognosis in GC patients.PMID:34855064 | DOI:10.1245/s10434-021-11132-5
Source: Ann Oncol - December 2, 2021 Category: Cancer & Oncology Authors: Shunji Kato Atsushi Shiozaki Michihiro Kudou Hiroki Shimizu Toshiyuki Kosuga Takuma Ohashi Tomohiro Arita Hirotaka Konishi Shuhei Komatsu Takeshi Kubota Hitoshi Fujiwara Kazuma Okamoto Mitsuo Kishimoto Eiichi Konishi Eigo Otsuji Source Type: research
PCSK9 as a new player in cancer: New opportunity or red herring?
Curr Med Chem. 2021 Nov 15. doi: 10.2174/0929867328666211115122324. Online ahead of print.ABSTRACTInitially described as a factor involved in liver regeneration and neuronal differentiation, proprotein convertase subtilisin/kexin type 9 (PCSK9) has become one of the key regulators of low-density lipoprotein cholesterol. Besides that, a number of studies have suggested PCSK9 may play a role in cancer biology. This is particularly true for gastroenteric (gastric and liver cancers) and lung cancers, where higher PCSK9 levels were associated with the increased ability of the tumor to develop and give metastasis as well as with...
Source: Current Medicinal Chemistry - November 16, 2021 Category: Chemistry Authors: Aldo Bonaventura Alessandra Vecchi é Massimiliano Ruscica Francesco Grossi Francesco Dentali Source Type: research
Flotillin-1 promotes progression and dampens chemosensitivity to cisplatin in gastric cancer via ERK and AKT signaling pathways
CONCLUSION: Flotillin-1 might be used as a molecular marker for GC diagnosis and could be explored as a potential new target for the treatment of GC.PMID:34774850 | DOI:10.1016/j.ejphar.2021.174631
Source: European Journal of Pharmacology - November 14, 2021 Category: Drugs & Pharmacology Authors: Jiahui Wei Ruiqing Wang Yiran Lu Song He Bao Yuan Jiabao Zhang Yu Ding Source Type: research
HER2 promotes epithelial-mesenchymal transition through regulating osteopontin in gastric cancer
CONCLUSIONS: These findings indicate that HER2 may promote EMT via the regulation of OPN in GCs.PMID:34634565 | DOI:10.1016/j.prp.2021.153643
Source: Pathology, Research and Practice - October 11, 2021 Category: Pathology Authors: Yalan Liu Lingli Chen Dongxian Jiang Lijuan Luan Jie Huang Yingyong Hou Chen Xu Source Type: research
