Filtered By:
Cancer: Gastric (Stomach) Cancer
This page shows you your search results in order of date. This is page number 3.
Order by Relevance | Date
Total 1410 results found since Jan 2013.
Inhibition of EP2 receptor suppresses tumor growth and chemoresistance of gastric cancer
In this study, we found that expression of EP2 receptor was significantly upregulated in gastric cancer. Inhibition of EP2 receptor reduced gastric cancer cell proliferation, induced cell cycle arrest proteins, and enhanced cell apoptosis. Moreover, knockdown of EP2 receptor by siRNA or antagonist sensitized gastric cancer cells to ECF. Silence of EP2 receptor also significantly abrogated gastric cancer growth in a mice model. Analysis revealed that CAV1 was a downstream target of EP2 receptor in gastric cancer. Our findings illustrated that blocking EP2 receptor reduced tumor growth and induced apoptosis in gastric cancer...
Source: Cell Research - November 16, 2022 Category: Cytology Authors: Vivian Yvonne Shin Michelle Xin Liu Jennifer Man-Ting Siu Ava Kwong Kent-Man Chu Source Type: research
High Expression of Pregnancy Specific Beta-1-glycoprotein 1 Is Associated With Poor Gastric Cancer Prognosis
CONCLUSION: PSG1 is up-regulated in gastric cancer and may serve as an oncogene that promotes cell proliferation, migration, and invasion. PSG1 is an independent prognostic factor for the progression of gastric cancer and may be a potential biomarker and therapeutic target for gastric cancer.PMID:36309385 | DOI:10.21873/invivo.13005
Source: Cancer Control - October 29, 2022 Category: Cancer & Oncology Authors: Hyeon-Gu Kang Seok-Jun Kim Source Type: research
Nur77 promotes invasion and migration of gastric cancer cells through the NF- κB/IL-6 pathway
CONCLUSION: A high Nur77 expression is strongly correlated with a poor prognosis of gastric cancer patients. Nur77 promotes the invasion and migration of gastric cancer cells possibly by regulating the NF-κB/IL-6 signaling pathway.PMID:36210716 | PMC:PMC9550556 | DOI:10.12122/j.issn.1673-4254.2022.09.19
Source: Journal of Southern Medical University - October 10, 2022 Category: Universities & Medical Training Authors: W Li Y Shi Y Guo S Tian Source Type: research
