[Overexpression of histone deacetylase 11 suppresses basal-like breast cancer cell invasion and metastasis].
CONCLUSIONS: Our data suggest that HDAC11 acts as a negative modulator of invasion and metastasis of BLBC cells. PMID: 31340905 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Yi Z, Wenwen L, Kun W, Jian S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Matrine inhibits proliferation and promotes autophagy and apoptosis in non-small cell lung cancer cells by deactivating PI3K/AKT/mTOR pathway].
CONCLUSIONS: We demonstrate that matrine inhibits the proliferation and induces autophagy and apoptosis of A549 cells by deactivating AKT pathway, suggesting the potential of matrine as an anti-cancer agent for lung cancer. PMID: 31340906 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Hao Y, Yin H, Zhu C, Li F, Zhang Y, Li Y, Wang X, Li D Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Causes of oocyte vitrification and its value in assisted reproductive technology].
CONCLUSIONS: Oocytes vitrification can be used as a remedy for infertile couples who fail to provide sperms due to male factors on the day of oocyte retrieval. Vitrification of the oocytes does not significantly affect the fertilization rate or the clinical pregnancy rate. The survival rate of the thawed oocytes is related to the age of the wife, and an age younger than 35 years can be optimal for achieving favorable clinical pregnancy outcomes after oocyte vitrification. PMID: 31340907 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Zhe J, Zhang J, Chen S, Zhang W, Luo C, Zhou X, Chen X, Qiu Z, Li H, Wu X Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Dynamic imaging of melanoma development in nude mice using high-frequency ultrasound and optical coherence tomography].
CONCLUSIONS: HFUS and OCT can monitor the dynamic development of cutaneous melanoma in nude mice, and their imaging performance differs in different stages of tumor development. PMID: 31340908 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Huang Y, Liu Y, Xin X Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Protective effect of procyanidin B2 on intestinal barrier and against enteritis in a mouse model of trinitrobenzene sulphonic acid-induced colitis].
CONCLUSIONS: PCB2 suppresses intestinal inflammation and protects intestinal mucosal functions and structural integrity by inhibiting intestinal PI3K/AKT signaling pathway, suggesting the potential of PCB2 as a new drug for Crohn's disease. PMID: 31340909 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Jiang C, Zhu P, Shi Y, Xiang W, Ge S, Zhang Z, Zuo L Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Role of miRNA-340 in modulating gastric cancer cell proliferation and bioinformatic analysis].
CONCLUSIONS: miRNA-340 may play the role of a tumor suppressor in tumorigenesis and progression. Overexpression of miRNA-340 suppress the proliferation of GC cells, suggesting its involvement in the development of GC along with multiple circRNAs. PMID: 31340910 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Wang J, Chen W, Lin H, Zhang J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Hyaluronate acid for treatment of chondromalacia patellae: a 52-week follow-up study].
CONCLUSIONS: HA injection through the subpatellar route is effective for treatment of CP. HA injection produces better long-term efficacy for treatment of early CP than for advanced CP where patellofemoral arthritis occurs. PMID: 31340911 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Zhang S, Jia M, Luo Y, Wang X, Shi Z, Xiao J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[SRC kinase inhibitor PP2 inhibits invasion and metastasis of lung cancer A549 cells by upregulating connexin43 expression].
CONCLUSIONS: PP2 treatment can suppress the invasion and metastasis of A549 cells in vitro possibly by modulating the expression of Cx43. PMID: 31340912 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Wang D, Liu Y, Zhao W, Wang R, Tong X, Jiang G Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Role of TGF- β1/ILK/FSP1 signaling pathway in cyclosporin A-induced epithelialmesenchymal transition in cultured renal tubular epithelial cells].
CONCLUSIONS: The activation of TGF-β1/ILK/FSP-1 signaling pathway is an important mechanism for CsA-induced transdifferentiation in rat renal tubular epithelial cells. ILK participates in CsA-induced epithelialmesenchymal transition of renal tubular epithelial cells. PMID: 31340913 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Bai Z, Lu J, Yang Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Angiotensin Ⅱ induces apoptosis of HEK293T cells by up-regulating Cyr61 expression].
CONCLUSIONS: The up-regulation of Cyr61 expression is related with AngⅡ-induced injury in HEK293T cells, and down-regulating Cyr61 expression can effectively protect HEK293T cells against AngⅡ-induced injury. PMID: 31340914 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Wang J, Jiang Y, Soulixay S, Fu D, You Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Protective effect of vitamin D against hyperoxia-induced bronchopulmonary dysplasia in newborn mice].
CONCLUSIONS: In newborn mice with BPD, VD supplement can increase the weight of the lungs and promote lung maturation, and a higher concentration of VD can better protect the lungs and promote the growth of pulmonary blood vessels. PMID: 31340915 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Chen H, Chen X, Chen J, Zhao H, Wang B, Zheng W, Lü J, Du J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Design, screening and antimicrobial activity of novel peptides against Streptococcus mutans].
CONCLUSIONS: Hydrophobicity and imperfect amphipathic structure are two key parameters that define the antimicrobial potency of the antimicrobial peptides. The imperfectly amphipathic peptide AT-7 shows the potential for clinical application in dental caries treatment. PMID: 31340916 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Liang D, Li H, Xu X, Liang J, Dai X, Zhao W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Efficacy of local infiltration of ropivacaine combined with multimodal analgesia with parecoxib for perioperative analgesia in patients undergoing pancreaticoduodenectomy].
CONCLUSIONS: In patients undergoing pancreaticoduodenectomy, local infiltration of ropivacaine combined with multimodal analgesia with ropivacaine can effectively relieve perioperative pain, reduce the use of relief analgesics, lower the incidence of adverse reactions, and promote the recovery after the surgery. PMID: 31340917 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Feng J, Li K, Feng H, Han Q, Gao M, Xu R Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Effects of low-intensity pulsed ultrasound on hematopoietic function in rats after combined chemotherapy with doxorubicin and cyclophosphamide].
CONCLUSIONS: LIPUS can alleviate the hematopoietic damage after combined chemotherapy with doxorubicin with cyclophosphamide probably by increasing the expressions of ICAM- 1, VCAM-1, IL- 3, and GM-CSF. PMID: 31340918 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Luo D, Wang W, Chen J, Liu B, Chen J, Wang Y, Chen W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Application of femtosecond laser technology in the management of subluxated lens].
CONCLUSIONS: The application of femtosecond laser assisted technology enhances the surgical safety and effectiveness for subluxated lens, facilitates the choice of individualized surgical options, and promotes maximum recovery of the patients' visual function. PMID: 31340919 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Ju R, Chen Y, Yang W, He M, Pan Y, Wu Z Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Effect of ulinastatin on isoflurane-induced neuronal apoptosis in the hippocampus of rats].
CONCLUSIONS: Ulinastatin pretreatment provides neuroprotection against isoflurane-induced apoptosis of the hippocampal neurons in rats possibly by inhibiting mitochondria-dependent apoptosis pathway. PMID: 31340920 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Guo Y, Wang Y, Zhang D, Cui C, Li T, Wang S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Effect of traditional Chinese medicine for replenishing qi, nourishing yin and activating blood on renal Notch/Hes1 signaling in rats with diabetic nephropathy].
CONCLUSIONS: The Traditional Chinese medicine (TCM) capsule for replenishing qi, nourishing yin and activating blood can reduce Hes1, CD34 and CD144 in kidney tissue of model rats, play a protective role on kidney function and delay the development of DN. PMID: 31340921 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Zhou X, Xu C, Wang K, Chu Q, Dong C, Wu C, Zhao J, Li L, Wang L Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Association of metabolic syndrome with chronic kidney disease in premenopausal and postmenopausal women].
CONCLUSIONS: MS is correlated with CKD in both premenopausal and postmenopausal women, and the association is dependent on diabetes, hypertension, and hyperuricemia in premenopausal women but not in postmenopausal women. PMID: 31340922 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Xu W, Li C, Qian G, Huang Y, Zhao L Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Role of lipophagy in the regulation of lipid metabolism and the molecular mechanism].
Abstract Recent studies have discovered a selective autophagy-lipophagy, which can selectively identify and degrade lipids and plays an important role in regulating cellular lipid metabolism and maintaining intracellular lipid homeostasis. The process of lipophagy can be directly or indirectly regulated by genes, enzymes, transcriptional regulators and other factors. This review examines the role of lipophagy in reducing liver lipid content, regulating pancreatic lipid metabolism, and regulating adipose tissue differentiation, and summarizes the findings of the molecules (Rab GTPase, enzymes, ion channels, transcr...
Source: Journal of Southern Medical University - July 27, 2019 Category: Universities & Medical Training Authors: Shi L, Wang K, Deng Y, Wang Y, Zhu S, Yang X, Liao W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[rhPDCD5 suppresses pro-inflammatory cytokine secretion and proliferation and induces apoptosis of activated lymphocytes from rats with collagen-induced arthritis].
CONCLUSIONS: rhPDCD5 reduces pro-inflammatory cytokine secretion, inhibits the proliferation and promotes activation-induced cell death of activated CD4 + lymphocytes to produce immunosuppression in rat models of CIA. PMID: 31270039 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Wanlin W, Chun M, Juan X Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Antiviral and antifibrotic therapies reduce occurrence of hepatocellular carcinoma in patients with chronic hepatitis B and liver fibrosis: a 144-week prospective cohort study].
CONCLUSIONS: Antiviral therapy combined with antifibrotic therapy can effectively reverse hepatic fibrosis and reduce the incidence of HCC in patients with CHB; among the 3 antiviral drugs, tenofovir dipivoxil can be a better option for reducing the incidence of HCC in these patients. PMID: 31270040 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Zhou Y, Hu C, Yuan G, Liu J, Ren Y, Tang C, Yang S, Dai L, Li Y, Yang D Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Identification of differentially expressed genes between lung adenocarcinoma and squamous cell carcinoma using transcriber signature analysis].
CONCLUSIONS: Through transcriptome analysis, we identified candidate genes, paired microRNAs and pathways for differentiating LUAD and LUSC, and they can provide novel differential diagnosis and therapeutic strategies for LUAD and LUSC. PMID: 31270041 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Peng S, Li X, Liu Q, Zhang Y, Zou L, Gong X, Wang M, Ma X Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Medium-chain acyl-CoA dehydrogenase enhances invasion and metastasis ability of breast cancer cells].
CONCLUSIONS: ACADM can promote the EMT process of breast cancer cells and improve the migration and invasion ability. ACADM is an oncogene in breast cancer. PMID: 31270042 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Yu Y, Zhao L, Li R Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Effect of dietary sodium intake on residual renal function in patients undergoing peritoneal dialysis: a prospective study of 33 cases].
CONCLUSIONS: Sodium excretion by PD in patients with continuous ambulatory PD is positively correlated with their dietary sodium intake, which contribute to the decrease of residual renal function. A high dietary sodium intake may accelerate the reduction of residual renal function in these patients. PMID: 31270043 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Hu J, Hu L, Gong N, Zhang L, Tian J, Jiang J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Predictive value of inflammatory indicators for post-stroke depression in patients with ischemic stroke].
CONCLUSIONS: Elevated NLR and PLR at admission and levels of IL-17 and IL-6 at 2 weeks after admission are all independent predictors of the occurrence of PSD at 3 months after stroke. PMID: 31270044 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Hu J, Zhou W, Zhou Z, Yang Q, Han J, Yan Y, Dong W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Simvastatin promotes murine osteoclasts apoptosis in vitro through NFATc1 pathway].
CONCLUSIONS: SIM promotes osteoclast apoptosis through NFATc1 signaling pathway. PMID: 31270045 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Yu D, Zhao D, Yang D, Yang G Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Long noncoding RNA UFC1 promotes metastasis and invasion of hepatocellular carcinoma cells in vitro via GSK-3 β/β-catenin axis].
CONCLUSIONS: lincRNA-UFC1 overexpresison promotes cell invasion and migration through the GSK-3β/β-catenin axis in HCC cells in vitro. PMID: 31270046 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Wang J, Cao C, Zeng Q, Dong Z Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Formation of gap junctions between adipose stem cells-derived Schwann cells in a rat model of dyskinesia induced by brain injury].
CONCLUSIONS: In the rat model of dyskinesia induced by brain injury, transplantations of adipose stem cells and adipose stem cells-derived Schwann cells both promote the functional recovery of brain damage, in which gap junction protein Cx43 plays an important role to promote functional gap junction formation possibly by enhancing NGF expression. PMID: 31270047 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Yang Y, Yang L, Wang Z Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[The improvewment of DNA library construction in non-crosslinked chromatin immunoprecipitation coupled with next-generation sequencing].
CONCLUSIONS: Tn5 transposase method improves the efficiency of DNA library construction and the results of subsequent sequence analysis, and is especially suitable for detecting histone modification in the DNA to provide a better technical option for epigenetic studies. PMID: 31270048 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Peng A, Li Z, Zhang Y, Feng D, Hao B Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[A non-coated enzyme-linked immunosorbent assay for screening zika virus envelope protein].
CONCLUSIONS: A non- coated ELISA method based on zika virus E protein was established, which can be used for screening antiviral agents against zika virus. PMID: 31270049 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Liu H, Zhou W, Liao H, Hu Z, Zou M, Liu S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Plasma miRNA-23a and miRNA-451 as candidate biomarkers for early diagnosis of nonsmall cell lung cancer: a case-control study].
CONCLUSIONS: miRNA-23a and miRNA-451 can be used as potential biomarkers for early diagnosis of NSCLC, and their combined detection can be more effective for the diagnosis. PMID: 31270050 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Cui S, Cao Z, Guo W, Yu H, Huang R, Wu Y, Zhou Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Long-pulsed 1064 nm Nd: YAG laser combined with terbinafine against chromoblastomycosis caused by Fonsecaea nubica and the effect of laser therapy in a Wistar rat model].
We report a case of chromoblastomycosis caused by Fonsecaea nubica, which was successfully treated by long-pulsed 1064 nm Nd: YAG laser combined with terbinafine. A 60-year-old man was admitted for the presence of a 30 mm×40 mm erythematous plaque on the dorsum of his right hand for about 10 months without any subjective symptoms. Both microscopic examination and tissue biopsy of the lesion showed characteristic sclerotic bodies of chromoblastomycosis. Lesion tissue culture on SDA at 26 ℃ for 2 weeks resulted in a black colony, and slide culture identified the isolate as Fonsecaea species. ITS sequence analysis of ...
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Luo J, Feng P, Hu Y, Yang Y, Zhou S, Huang S, Jadad A, Zhong Z, Zheng Y, Liu K, Lu Y, Hu Y, Zhou X Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Improvement of a mouse model of valproic acid-induced autism].
CONCLUSIONS: The mouse model of autism established using the modified method better mimics human autism with reduced mortality and abortion rates of the pregnant mice and also decreased mortality rate of the newborn mice. PMID: 31270052 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Zheng W, Hu Y, Chen D, Li Y, Wang S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Correlation between methylation level of CDKN2A and CDKN2B genes and aging in healthy individuals].
CONCLUSIONS: The methylation levels of CDKN2A and CDKN2B are closely related to age and the levels of multiple proteins in healthy subjects. PMID: 31270053 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Zheng Z, Ji H, Chen C, Li Y, Duan S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Two-stage closed sinus lift for severe bone deficiency in the posterior maxilla imrpoves long-term clinical outcomes].
CONCLUSIONS: Compared with lateral wall lifting, two-stage close lifting of the maxillary sinus floor is associated with less trauma and less discomfort, and effectively solves the problem of severe alveolar bone height deficiency in the maxillary posterior region to achieve favorable long-term clinical outcomes. PMID: 31270054 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Zhou Z, Wang Y, Meng W, Yang X, Dao J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Efficacy of erector spinae block versus retrolaminar block for postoperative analgesia following posterior lumbar surgery].
CONCLUSIONS: Ultrasound-guided RLB has better analgesic effect than ESPB for management of perioperative pain following posterior lumbar surgery. PMID: 31270055 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Tao T, Zhou Q Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Conjugated linoleic acid improves glucose and lipid metabolism in diabetic mice].
CONCLUSIONS: The mixture of two conjugated linoleic acid isomers can reduce fasting blood glucose, increase glucose tolerance and improve glycolipid metabolism in db/db mice by enhancing the expression of PPARα, increasing P-ACC and inhibiting CD36 expression. PMID: 31270056 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Xia J, Zheng M, Li L, Hou X, Zeng W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Pannus does not occur only in rheumatoid arthritis: a pathological observation of pannus of knee osteoarthritis].
CONCLUSIONS: Pannus formation occurs also in the synovium of OA patients but with milder FLS hyperplasia, fibrosis and lymphocyte infiltration and a lower rate of plasma cell infiltration compared with the pannus in RA patients. These differences in the pannus between OA and RA can be of potential value in the diagnosis and treatment of the patients. PMID: 31270057 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - June 30, 2019 Category: Universities & Medical Training Authors: Chen Y, Qiu F, Zhu X, Mo H, Wu Z, Xiao C Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Psychoanalytic therapy for a child with somnambulism: a case report].
Abstract Somnambulism is defined as a state of dissociated consciousness triggered by impaired arousal, which results in partial wakefulness and partial sleep. No effective therapy or medication has been available for treating children with somnambulism. Herein we present a case in a 4.5-year-old girl, who presented with somnambulism associated with separation anxiety disorder every night in a week. The girl received formal assessment and appropriate interventions, and the symptoms disappeared within a week. The treatment was carried out in 5 stages: diagnosis of the disease, establishment of trust, information co...
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Xixi J, Yuncheng Z, Weidong JI Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Blocking pannexin-1 alleviates cisplatin-induced acute kidney injury in mice by reducing renal inflammatory cell infiltration].
CONCLUSIONS: In cisplatin induced acute kidney injury mice model, Pannexin-1 expression is up-regulated in the kidneys tissue, and blocking pannexin-1 alleviates the acute kidney injury via reducing renal inflammatory cell infiltration. PMID: 31140412 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Liu C, Huang L, Li C, Shen Y, Wang J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Transient expression of bioactive recombinant human plasminogen activator in tobacco leaf].
CONCLUSIONS: Enzymatically active recombinant rhPA can be rapidly expressed in tobacco plants using the plant viral ampliconbased system, which offers a promising alternative for cost-effective production of recombinant rhPA. PMID: 31140413 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Ma J, Wu L, Ding X, Li Z, Wang S Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Effects of mitochondrial aldehyde dehydrogenase 2 on autophagy-associated proteins in neonatal rat myocardial fibroblasts cultured in high glucose].
CONCLUSIONS: Mitochondrial ALDH2 inhibits the proliferation of neonatal rat cardiac fibroblasts induced by high glucose, and the effect is possibly mediated by the up-regulation of autophagy-related proteins Beclin-1 and LC3B. PMID: 31140414 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Tang B, Kang P, Guo J, Zhu L, Xu Q, Gao Q, Zhang H, Wang H Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Evaluation of renal oxygenation in rats with acute aristolochic acid nephropathy using blood oxygenation level-dependent magnetic resonance imaging].
CONCLUSIONS: BOLD MRI allows non-invasive measurement of renal oxygenation levels in rats with AAN. The increase of renal cortical and medullary R2* values, and particularly the latter, indicates a lowered renal oxygenation level, which provides potentially useful information for clinical decisions. PMID: 31140415 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Yang G, Mei Y, Lü J, Tao Q, Feng Y, Xu Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[MicroRNA-152 and microRNA-448 inhibit proliferation of colorectal cancer cells in vitro by targeting Rictor].
CONCLUSIONS: miR-152 and miR-448 can down-regulate the protein expression of Rictor by targeting Rictor mRNA to negatively regulate the growth and colony formation of colorectal cancer cells. PMID: 31140416 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Zhang J, Han Z, Dong L, Li Z, Li K, Shi M, Liu Z, Li J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Bioinformatics analysis of COL1A1 regulated by miR-129-5p as a potential therapeutic target for gastric cancer].
CONCLUSIONS: COL1A1 under regulation by MiR-129-5p is a potential therapeutic target for gastric cancer. PMID: 31140417 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Yang W, Pan Y, Guan P, Li X, You C Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[A radiomic approach to differential diagnosis of renal cell carcinoma in patients with hydronephrosis and renal calculi].
ConclusionThe computer-aided classification model based on supervised machine learning can effectively extract the diagnostic information and improve the diagnostic rate of renal cell carcinoma associated with hydronephrosis and renal calculi. PMID: 31140418 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Zhang H, Li Q, Li S, Ma J, Huang J Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Cbl-b gene silencing enhances H9 T lymphocyte-mediated killing of human laryngeal squamous cancer Hep-2 cells].
CONCLUSIONS: Cbl-b gene silencing effectively enhances the killing effect of H9 T lymphocytes against Hep-2 cells in vitro probably as the result of enhanced IL-2 secretion and T lymphocyte activation. PMID: 31140419 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Chen S, Li Z, Zhou L, Zhang Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Role of PPAR- γ-regulated autophagy in genistein-induced inhibition of hepatic stellate cell activation].
CONCLUSIONS: PPAR-γ- regulated autophagy plays an important role in mediating genistein-induced inhibition of HSC activation in vitro. PMID: 31140420 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Liu X, Zhang M, Zhang H, Zhao A, Sun J, Tang W Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Mig-7 gene silencing inhibits vasculogenic mimicry formation and invasion of glioma U251 cells in vitro by suppressing MEK/ERK signaling].
CONCLUSIONS: Silencing of Mig-7 gene inhibits vasculogenic mimicry formation and invasion of U251 cells possibly by suppressing MEK/ERK signaling, suggesting the important role of Mig-7 gene in vasculogenic mimicry formation and invasion of human glioma cells. PMID: 31140421 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Wang F, Chen F, Hu W, Zhang Y Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Risk factors analysis of gestational diabetes mellitus based on International Association of Diabetes Pregnancy Study Groups criteria].
CONCLUSIONS: The onset of GDM was affected by multiple factors. Age, history of GDM, family history of diabetes, and a large arm circumference are all independent risk factors of GDM and should be controlled to reduce the incidence of GDM. PMID: 31140422 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - May 30, 2019 Category: Universities & Medical Training Authors: Wang Y, Luo B Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research