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Total 331 results found since Jan 2013.

Management of Eosinophilic Esophagitis: Dietary and Nondietary Approaches.
Abstract Eosinophilic esophagitis (EoE) is an allergen-driven chronic inflammatory condition, characterized by symptoms related to esophageal dysfunction and confirmed histologically by esophageal mucosal eosinophilia. Since its first description in the 1990s, the incidence and prevalence of EoE have been on the rise. It is known to affect all ages of various ethnic backgrounds and both sexes; however, it is most seen in White males. Children with EoE often present with abdominal pain, nausea, vomiting, and failure to thrive, whereas adults with EoE typically present with dysphagia and food impaction. Diagnosis of...
Source: Nutrition in Clinical Practice - August 20, 2020 Category: Nutrition Authors: Chen JW Tags: Nutr Clin Pract Source Type: research

Human Ascariasis: An Updated Review.
CONCLUSION: The average cure rate with anthelminthic treatment is over 95%. Unfortunately, most treated patients in endemic areas become re-infected within months. Health education, personal hygiene, improved sanitary conditions, proper disposal of human excreta, and discontinuing the use of human fecal matter as a fertilizer are effective long-term preventive measures. Targeting deworming treatment and mass anthelminthic treatment should be considered in regions where A. lumbricoides is prevalent. PMID: 32628606 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - July 7, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Effect of Dextrose Prolotherapy, Platelet Rich Plasma and Autologous Conditioned Serum on Knee Osteoarthritis: A Randomized Clinical Trial.
In this study, the clinical efficiency of Dextrose prolotherapy, platelet-rich plasma (PRP) and autologous conditioned serum (ACS) injection on the level of pain and function in Knee OA were compared. A randomized clinical trial was directed on 92 knee OA patients. Patients were randomly divided into three groups: 30 were received dextrose prolotherapy once in a week for three weeks, 30 received autologous PRP for two times with seven days interval, and in the remaining 32 patients 2ml of ACS were injected two times every seven days. Study participants were measured through the Western Ontario and McMaster Universities (WO...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 22, 2020 Category: Allergy & Immunology Authors: Pishgahi A, Abolhasan R, Shakouri SK, Soltani-Zangbar MS, Dareshiri S, Ranjbar Kiyakalayeh S, Khoeilar A, Zamani M, Motavalli Khiavi F, Pourabbas Kheiraddin B, Mehdizadeh A, Yousefi M Tags: Iran J Allergy Asthma Immunol Source Type: research

Effectiveness Comparison of Dexmedetomidine and Remifentanil for Perioperative Management in Patients Undergoing Endoscopic Sinus Surgery.
CONCLUSION: Dexmedetomidine had better postoperative sedative and analgesic effects than remifentanil for patients undergoing endoscopic sinus surgery in this study. Remifentanil and dexmedetomidine attenuated acute hemodynamic responses to be within normal ranges after intranasal injection of epinephrine, and no significant differences in terms of hemodynamic variables. Remifentanil was superior to dexmedetomidine in inducing hypotension during endotracheal intubation. PMID: 32438817 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - May 20, 2020 Category: ENT & OMF Authors: Huh H, Park JJ, Seong HY, Lee SH, Yoon SZ, Cho JE Tags: Am J Rhinol Allergy Source Type: research

Long-term Safety and Efficacy of Subcutaneous C1-Inhibitor in Older Patients With Hereditary Angioedema.
CONCLUSION: C1-INH (SC) was well tolerated and effective in the management of HAE in these subjects ≥65 years old with multiple comorbid conditions and polypharmacy. PMID: 32445670 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 19, 2020 Category: Allergy & Immunology Authors: Bernstein JA, Schwartz L, Yang W, Baker J, Anderson J, Farkas H, Aygören-Pürsün E, Bygum A, Jacobs I, Feuersenger H, Pragst I, Riedl MA Tags: Ann Allergy Asthma Immunol Source Type: research

Anti ‐plexin D1 antibody–mediated neuropathic pain
AbstractNeuropathic pain (NeP) is an intractable pain caused by a lesion or disease of the somatosensory nervous system. NeP is often challenging to manage because most of the mechanisms remain to be elucidated. Recent investigations in the field of autoimmune neurology have demonstrated that specific autoantibodies against antigens in the somatosensory pathway can cause NeP. Detection of pathogenic autoantibodies in NeP adds to the understanding of the mechanism of pain, which might aid in the development of novel immunotherapies. Therefore, it is necessary to explore novel NeP ‐related autoantibodies to improve the man...
Source: Clinical and Experimental Neuroimmunology - March 31, 2020 Category: Neurology Authors: Takayuki Fujii, Ryo Yamasaki, Yukino Miyachi, Kyoko Iinuma, Jun ‐ichi Kira Tags: REVIEW ARTICLE Source Type: research

NIDCR's Spring 2020 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News CDC’s COVID-19 Guidance for Dental Settings  Dental health care personnel can find COVID-19-related information on the CDC’s Division of Oral Health website, which offers guidance and resources for clinics and health care facilities and recommendations for respondi...
Source: NIDCR Science News - March 27, 2020 Category: Dentistry Source Type: news

Acute Myocarditis in Children: An Overview of Treatment and Recent Patents.
CONCLUSIONS: This article reviews the current literature regarding etiology, clinical manifestations, diagnosis, and management of acute myocarditis in children. PMID: 32013855 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - February 6, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Reported drug allergies among patients with opioid use disorder
Patients with opioid use disorder (OUD) are high utilizers of the health care system, in part due to challenges of pain management and frequent infectious complications. Characteristics of reported drug allergies in this population are unknown.
Source: Journal of Allergy and Clinical Immunology - January 31, 2020 Category: Allergy & Immunology Authors: Lily Li, Christin Price, Joji Suzuki, Tanya Laidlaw Source Type: research

Development of the Hereditary Angioedema Rapid Triage Tool
ConclusionsExpert consensus led to the identification and prioritization of variables that when incorporated into an HAE-RT tool were associated with a high level of sensitivity and specificity when applied to known patients.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 16, 2020 Category: Allergy & Immunology Source Type: research

Localized carbon dioxide laser treatment of a recalcitrant oral ulceration in pemphigus vulgaris
ConclusionsAdjunctive procedures that can facilitate a decrease in the cumulative dosages of corticosteroids and immunosuppressants have great value in the management of PV. CO2 laser vaporization is a safe procedure with minimal morbidity and no long-term side effects and should be considered as an adjunctive treatment option for management of recalcitrant lesions in patients with oral PV.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - December 15, 2019 Category: ENT & OMF Source Type: research

Chronic rhinosinusitis in eosinophilic granulomatosis with polyangiitis: clinical presentation and antineutrophil cytoplasmic antibodies
ConclusionCRS in patients with EGPA is often refractory to medical and surgical management. Treatment of these patients should occur in a multidisciplinary setting.
Source: International Forum of Allergy and Rhinology - December 1, 2019 Category: Allergy & Immunology Authors: Christopher M. Low, Karina A. Keogh, Elias S. Saba, Nelson R. Gruszczynski, Alvise Berti, Ulrich Specks, Misbah Baqir, Byron M Smith, Garret Choby, Janalee K. Stokken, Erin K. O'Brien Tags: ORIGINAL ARTICLE Source Type: research

Clinical Manifestations and Diagnostic Evaluation of Opioid Allergy Labels - A Review.
Authors: Kalangara J, Potru S, Kuruvilla M Abstract While opioids represent one of the most common medication allergy labels, these labels are often unsubstantiated in clinical practice. The removal of erroneous opioid allergy labels has a unique importance in the population with acute or chronic pain. The current approach to patients with pseudo-allergy to opioids is switching to an alternative opioid with less histamine release. Thus, allergy labels to relatively lower potency opioids such as codeine may be feasibly result in the prescription of stronger medications like fentanyl that would otherwise not be indic...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 24, 2019 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Impact of palliative treatment on survival in sinonasal malignancies
ConclusionIn this study we identify the impact of palliative treatment modalities on survival in sinonasal cancer. Palliative surgery was shown to have the highest 1Y ‐OS and M‐OS compared with other palliative treatment modalities.
Source: International Forum of Allergy and Rhinology - September 19, 2019 Category: Allergy & Immunology Authors: Nicole I. Farber, Roman Povolotskiy, Richard D. Bavier, Julia Riccardi, Jean Anderson Eloy, Wayne D. Hsueh Tags: ORIGINAL ARTICLE Source Type: research

Otitis Media: Rapid Evidence Review.
Abstract Acute otitis media (AOM) is the most common diagnosis in childhood acute sick visits. By three years of age, 50% to 85% of children will have at least one episode of AOM. Symptoms may include ear pain (rubbing, tugging, or holding the ear may be a sign of pain), fever, irritability, otorrhea, anorexia, and sometimes vomiting or lethargy. AOM is diagnosed in symptomatic children with moderate to severe bulging of the tympanic membrane or new-onset otorrhea not caused by acute otitis externa, and in children with mild bulging and either recent-onset ear pain (less than 48 hours) or intense erythema of the t...
Source: American Family Physician - September 14, 2019 Category: Primary Care Authors: Gaddey HL, Wright MT, Nelson TN Tags: Am Fam Physician Source Type: research