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Optimization of care for patients with hereditary angioedema living in rural areas
CONCLUSION: For HAE patients living in rural areas, optimal care is complicated by health disparities. Given the scarcity with which these topics have been covered in the literature to date, it is intended that this article will serve as the impetus for a range of further initiatives focused on improving access to care.PMID:34628006 | DOI:10.1016/j.anai.2021.09.026
Source: Annals of Allergy, Asthma and Immunology - October 10, 2021 Category: Allergy & Immunology Authors: Marc A Riedl Douglas T Johnston John Anderson J Allen Meadows Daniel Soteres Stephen B LeBlanc H James Wedner David M Lang Source Type: research
New Analysis Presented by Janssen at United European Gastroenterology Week (UEGW) Demonstrates Long-Term Safety Profile for STELARA ® (ustekinumab) in Older Patients Across Approved Indications
SPRING HOUSE, PENNSYLVANIA, October 4, 2021 – Today, the Janssen Pharmaceutical Companies of Johnson & Johnson announced a new analysis of STELARA® (ustekinumab) pooled safety data from 13 clinical studies across approved indications, showing rates of key safety events among adults 60 years and older treated with STELARA for up to five yearsa were similar to rates observed with placebo during the control phase of these trials.1,b Approved indications included adults with moderately to severely active Crohn’s disease (CD), moderately to severely active ulcerative colitis (UC), moderate to severe plaque psoriasis (P...
Source: Johnson and Johnson - October 4, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
A Qualitative Analysis of Provider Notes of Atopic Dermatitis-Related Visits Using Natural Language Processing Methods
ConclusionThe topics documented in case notes by healthcare providers about their patients with AD focus largely on symptoms and, to a lesser extent, treatment, but do not reflect the burden of AD on patients ’ lives. This finding highlights a potential care gap that warrants further investigation.
Source: Dermatology and Therapy - August 1, 2021 Category: Dermatology Source Type: research
Opioid use after endoscopic skull base surgery: A descriptive, prospective, longitudinal cohort study
ConclusionAfter ESBS, greater total opioid use was significantly associated with history of headaches and previous opioid use within 60 days. Overall, opioid use declined among all patients in the postoperative period, but several factors may contribute to longer duration of use.
Source: International Forum of Allergy and Rhinology - July 26, 2021 Category: Allergy & Immunology Authors: Ryan A. Rimmer,
Brian Scott,
Jasmina Pailet,
Nyssa Fox Farrell,
Jess C. Mace,
Kara Y. Detwiller,
Timothy L. Smith,
Aclan Dogan,
Sachin Gupta,
Peter Andersen,
Justin Cetas,
Mathew Geltzeiler Tags: ORIGINAL ARTICLE Source Type: research
American Rhinologic Society expert practice statement: Postoperative pain management and opioid use after sinonasal surgery
SummaryThe goal of this American Rhinologic Society expert practice statement (EPS) is to provide clinically applicable, evidence-based recommendations regarding pain management in sinonasal surgery. This EPS was developed following the recommended methodology and approval process as previously outlined. The topics of interest included preoperative counseling, local anesthesia, use of opioids for postoperative pain, use of nonopioid medication for postoperative pain, nonsteroidal anti-inflammatory drugs and bleeding, and use of gabapentin for pain control. Following a modified Delphi approach, 6 statements were developed, ...
Source: International Forum of Allergy and Rhinology - July 12, 2021 Category: Allergy & Immunology Authors: Jivianne T. Lee,
Corinna G. Levine,
Jonathan B. Overdevest,
Thomas S. Higgins,
R. Peter Manes,
Jeffrey A. Myhill,
Zachary M. Soler Tags: VIEWPOINT Source Type: research
Lactose Intolerance in Pediatric Patients and Common Misunderstandings About Cow's Milk Allergy
Pediatr Ann. 2021 Apr;50(4):e178-e185. doi: 10.3928/19382359-20210312-01. Epub 2021 Apr 1.ABSTRACTLactose intolerance is a common gastrointestinal condition caused by the inability to digest and absorb dietary lactose. Primary lactose intolerance is the most common type of lactose intolerance. It is one of the most common forms of food intolerance and occurs when lactase activity is reduced in the brush border of the small bowel mucosa. People may be lactose intolerant to varying degrees, depending on the severity of these symptoms. When lactose is not digested, it is fermented by gut microbiota, leading to abdominal pain,...
Source: Pediatric Annals - May 27, 2021 Category: Pediatrics Authors: Margherita Di Costanzo Giacomo Biasucci Ylenia Maddalena Carmen Di Scala Carmen De Caro Antonio Calignano Roberto Berni Canani Source Type: research
The importance of recognizing and managing a rare form of angioedema: hereditary angioedema due to C1-inhibitor deficiency
Postgrad Med. 2021 May 17. doi: 10.1080/00325481.2021.1905364. Online ahead of print.ABSTRACTThe majority of angioedema cases encountered in clinical practice are histamine-mediated (allergic); however, some cases are bradykinin-related (non-allergic) and do not respond to standard anti-allergy medications. Among bradykinin-related angioedema, hereditary angioedema (hae) is a rare, but chronic and debilitating condition. The majority of hae is caused by deficiency (type 1) or abnormal function (type 2) of the naturally occurring protein, c1-inhibitor (c1-inh)-a major inhibitor of proteases in the contact (kallikrein-bradyk...
Source: Postgraduate Medicine - May 17, 2021 Category: Internal Medicine Authors: Joshua Jacobs Teresa Neeno Source Type: research
