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Total 331 results found since Jan 2013.

Neuromyelitis optica in hiv: a case report and literature review
We present a case and review the literature. A 49 year old lady of African descent with known HIV diagnosed in 2004 – compliant with her antiretroviral medication, Atripla – was admitted with a 3 week history of thoracic back pain, spreading paraesthesia and weakness involving both legs, and constipation. Examination revealed a spastic paraparesis, a sensory level at T3/4 on the right and reduced vibration sense to the iliac crests bilaterally. MRI spine revealed increased signal within the cord from T3–7 in keeping with a longitudinally extensive transverse myelitis. CSF was acellular with normal protein...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Appleton, J. P., Kenton, A. Tags: Neurogastroenterology, Immunology (including allergy), HIV/AIDS, Cranial nerves, Multiple sclerosis, Pain (neurology), Spinal cord, Ophthalmology ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Management of Children With Hereditary Angioedema Due to C1 Inhibitor Deficiency
Hereditary angioedema (HAE) is a potentially life-threatening inherited disease characterized by attacks of skin swelling, severe abdominal pain, and upper airway swelling. Attacks typically begin in childhood, but the appropriate diagnosis is often missed. Attacks do not respond to epinephrine, antihistamines, or glucocorticoids. Recently, many effective drugs have been approved for treatment of adults with HAE, and the Medical Advisory Board of the HAE Patient’s Association has developed and reported treatment recommendations for adults. Only 1 medication is approved for treatment of children <12 years of age, a...
Source: PEDIATRICS - October 31, 2016 Category: Pediatrics Authors: Frank, M. M., Zuraw, B., Banerji, A., Bernstein, J. A., Craig, T., Busse, P., Christiansen, S., Davis-Lorton, M., Li, H. H., Lumry, W. R., Riedl, M., US Hereditary Angioedema Association Medical Advisory Board Tags: Allergy/Immunology, Immunologic Disorders Special Article Source Type: research

Oral Cavity and Allergy: Meeting the Diagnostic and Therapeutic Challenge
AbstractAllergic reactions of the oral mucosa are associated with diverse symptoms and can severely affect patients ’ quality of life. Oral mucosa changes such as stomatitis or lichenoid reactions can be the first evidence of a contact allergy, with oral lichenoid reactions after contact with dental restorations, especially amalgam fillings, being among the most common clinical reactions. Additives in foods and oral hygiene products may also cause allergic mucosal reactions. Subjective symptoms, such as pain, burning feeling, or dryness of the oral mucosa, as well as cheilitis or lip and facial swelling, may not only hav...
Source: Current Oral Health Reports - September 8, 2016 Category: Dentistry Source Type: research

Nasal and Sinus Symptoms and Chronic Rhinosinusitis in a Population ‐Based Sample
ConclusionsCRS is a highly prevalent and heterogeneous condition. Differences in risk factors and health outcomes across symptom subgroups may be indicative of differences in etiology that have implications for disease management.This article is protected by copyright. All rights reserved.
Source: Allergy - September 2, 2016 Category: Allergy & Immunology Authors: Annemarie G. Hirsch, Walter F. Stewart, Agnes S. Sundaresan, Amanda J. Young, Thomas L. Kennedy, J Scott Greene, Wen Feng, Bruce K. Tan, Robert P. Schleimer, Robert C. Kern, Alcina Lidder, Brian S. Schwartz Tags: Original Article: Epidemiology and Genetics Source Type: research

Erythema Multiforme Associated With Misoprostol: A Case Report
A 33-year-old healthy woman at 6 weeks of gestation without any underlying disease developed erythema multiforme (EM) after misoprostol. She had no history of herpes simplex virus infection and drug allergy to nonsteroidal anti-inflammatory drugs and antibiotic agents. Medical abortion was performed at 6 weeks' gestation. Later day, the patient developed oral lesions as several white bullae lesions in her buccal mucosa and hyperkeratotic lip plaques with mild pain. Then, lesions resolved within approximately 3 weeks. Microscopic finding of oral biopsy from beneath the tongue and lesions was performed. The result was consis...
Source: American Journal of Therapeutics - September 1, 2016 Category: Drugs & Pharmacology Tags: Case Reports Source Type: research

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 ‐Inhibitor deficiency
ConclusionsThe Pediatric‐focused International Consensus for the diagnosis and management of C1‐INH‐HAE patients was created.This article is protected by copyright. All rights reserved.
Source: Allergy - August 8, 2016 Category: Allergy & Immunology Authors: Henriette Farkas, Inmaculada Martinez ‐Saguer, Konrad Bork, Tom Bowen, Timothy Craig, Michael Frank, Anastasios E. Germenis, Anete S Grumach, Andrea Luczay, Varga Lilian, Andrea Zanichelli Tags: Original Article: Immunodeficiencies Source Type: research

Management of Functional Abdominal Pain in Children Management of Functional Abdominal Pain in Children
Find out what pediatric clinicians need to know regarding the management of functional abdominal pain.Archives of Disease in Childhood
Source: Medscape Allergy Headlines - August 4, 2016 Category: Allergy & Immunology Tags: Pediatrics Journal Article Source Type: news

BIOBRAD Study: The Search for Biomarkers of Bradykinin-Mediated Angio-Oedema Attacks
Conclusions: Exploration of changes in fibrinolysis-related markers (particularly D-dimers) is thus promising for the diagnosis of AE attacks in difficult-to-diagnose abdominal forms, although it was not able to differentiate between bradykinin and mast cell-mediated AE. Int Arch Allergy Immunol 2016;170:108-114
Source: International Archives of Allergy and Immunology - July 29, 2016 Category: Allergy & Immunology Source Type: research

Chronic Rhinosinusitis with Nasal Polyps
Publication date: July–August 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 4 Author(s): Whitney W. Stevens, Robert P. Schleimer, Robert C. Kern Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed by the presence of both subjective and objective evidence of chronic sinonasal inflammation. Symptoms include anterior or posterior rhinorrhea, nasal congestion, hyposmia, and/or facial pressure or pain that last for a duration of more than 12 weeks. Nasal polyps are inflammatory lesions that project into the nasal airway, are typically bila...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 6, 2016 Category: Allergy & Immunology Source Type: research

H1-Antihistamine Premedication in NSAID-Associated Urticaria
Conclusions and Clinical Relevance In the majority of patients with NSAID-induced or NSAID-exacerbated urticaria concurrently suffering from intermittent pain, a premedication regimen with 5 mg desloratadine 30 minutes before intake of a strong COX-I inhibitor seems to be effective, safe, and practicable.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 5, 2016 Category: Allergy & Immunology Source Type: research

Efficacy and safety of bupivacaine versus lidocaine in local anaesthesia of the nasopharynx: A meta-analysis.
CONCLUSION: Bupivacaine was found to have better promotion to pain control than did lidocaine for the patients after nasal surgery. Lidocaine had a significantly increased inhibition of bleeding in these postoperative patients; however, the efficacy between bupivacaine and lidocaine was unclear for the patients who had transnasal endoscopic examinations. PMID: 27368150 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - June 29, 2016 Category: ENT & OMF Authors: Yu X, Wang J, Huang L, Yu X, He Z Tags: Am J Rhinol Allergy Source Type: research

Immunoglobulin E‐Mediated Hypersensitivity Reaction to Ketamine
DiscussionThis case represents a likely immunoglobulin E‐mediated type I hypersensitivity reaction to ketamine, supported by elevated tryptase levels and positive intradermal skin testing. The interpretation of these results and likely mechanism of the hypersensitivity reaction are described. The patient and treating team were advised against subsequent use of ketamine, due to the risk of serious adverse systemic reaction with repeat exposure.
Source: Pain Practice - June 22, 2016 Category: Anesthesiology Authors: John Ozcan, Katherine Nicholls, Karin Jones Tags: Clinical Report Source Type: research

Immunoglobulin E ‐Mediated Hypersensitivity Reaction to Ketamine
DiscussionThis case represents a likely immunoglobulin E‐mediated type I hypersensitivity reaction to ketamine, supported by elevated tryptase levels and positive intradermal skin testing. The interpretation of these results and likely mechanism of the hypersensitivity reaction are described. The patient and treating team were advised against subsequent use of ketamine, due to the risk of serious adverse systemic reaction with repeat exposure.
Source: Pain Practice - June 22, 2016 Category: Anesthesiology Authors: John Ozcan, Katherine Nicholls, Karin Jones Tags: Clinical Report Source Type: research

Using the Literature to Understand Achilles' Fate.
Authors: Rakic VS Abstract According to Greek mythology, Achilles was fatally wounded in his heel, bled out, and died. Several unproven hypotheses mention poisoning, infection, allergy, hemophilia, thyrotoxic storm (ie, pain and stress), and suicide. The author, a plastic surgeon who often treats chronic wounds, proposes an additional scenario: Although not mortally wounded, Achilles was considered dead, because in his time a wounded hero was as good as a dead hero, so he lived out the remainder of his life as former hero with a chronic wound far away from everyone. To determine whether his injury was enough to cau...
Source: Ostomy Wound Management - May 19, 2016 Category: Surgery Tags: Ostomy Wound Manage Source Type: research

Flare in axial spondyloarthritis. The dark side of the outcome
Spondyloarthritis (SpA) is a chronic inflammatory rheumatic disease with many phenotypes,1 but the frame of the disease is still a matter of debate, particularly regarding the non-radiographic forms of axial SpA.2 3 The disease evolution may have several profiles, mainly related to the treatment strategy, balancing from periods of remission or low disease activity to flares of the disease. The recommended treatment strategies are supposed to be tailored to the disease activity, aiming to reach remission or low disease activity in a T2T strategy,4 with management of remission (reduction of dosage or increase in interval of ...
Source: Annals of the Rheumatic Diseases - May 9, 2016 Category: Rheumatology Authors: Wendling, D., Prati, C. Tags: Inflammatory bowel disease, Immunology (including allergy), Pain (neurology), Ophthalmology, Ankylosing spondylitis, Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis, Calcium and bone Editorials Source Type: research