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What are Common Causes of Anaphylaxis?
Discussion
Anaphylaxis is a potentially life-threatening hypersensitivity reaction of the body. Usually anaphylaxis is IgE mediated but complement-mediated immune complex reactions or IgG mediated reactions can cause anaphylaxis. Usually mucous membranes or skin are involved, but it is a systemic disease process with at least 2 systems involved (respiratory is second most common followed by gastrointestinal system). The epidemiology is difficult to discern but the estimated incidence is about 50-112 episodes per 100,000 person-years and estimated prevalence is 0.3-5.1%. There is data supporting an increased incidence. Over...
Source: PediatricEducation.org - May 17, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Johnson & Johnson Single-Shot COVID-19 Vaccine Phase 3 Data Published in New England Journal of Medicine
NEW BRUNSWICK, N.J., April 21, 2021 – Johnson & Johnson (the Company) today announced publication in the New England Journal of Medicine of primary data from the Phase 3 ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary and key secondary endpoints, and found that the Johnson & Johnson single-dose COVID-19 vaccine prevented hospitalization and death across all study participants ...
Source: Johnson and Johnson - April 21, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news
NIDCR's Spring 2021 E-Newsletter
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NIDCR's Spring 2021 E-Newsletter
In this issue:
NIDCR News
Funding Opportunities & Related Notices
NIH/HHS News
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Science Advances
Grantee News
NIDCR News
NIDCR & NIH Stand Against Structural Racism
NIDCR Director Rena D’Souza, DDS, MS, PhD, said in a statement that there is no place for structural racism in biomedical research, echoing remarks from NIH Director Francis Collins, MD, PhD, in his announcement of a new NIH initiative—called UNIT...
Source: NIDCR Science News - April 7, 2021 Category: Dentistry Source Type: news
Medical Malpractice Allegations in Nasal Turbinate Surgery
CONCLUSIONS: There are inherent litigation risks for surgeons when performing nasal turbinate surgery. Most claims against surgeons, are resolved in favor of the surgeon. Understanding the types of claims and legal arguments that are made by patients could help assessing the risks of a proposed litigation. Documenting clear indications for surgery and written informed consent may reduce litigations against surgeons.PMID:33722101 | DOI:10.1177/19458924211004052
Source: American Journal of Rhinology and Allergy - March 16, 2021 Category: ENT & OMF Authors: Steven M Coppess Sims G Weymuller Greg E Davis Source Type: research
Who Gets Pott ’ s Puffy Tumor?
Discussion
Pott’s puffy tumor (PPT) was first described by Sir Percivall Pott in 1775 and who also described other orthopaedic and oncological diseases subsequently named for him. “It is a subperiosteal abscess of the anterior wall of the frontal sinus associated with underlying frontal osteomyelitis.” The tender edema and swelling of the forehead is the sign of PPT. Associated fever, headache, and rhinorrhea along with similar problems such as postnasal drip or nasal congestion are common. Associated ophthalmological problems include peri-orbital or eyelid edema and/or preseptal cellulitis. Ptosis and di...
Source: PediatricEducation.org - March 1, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Reported drug allergies among patients with opioid use disorder
Patients with opioid use disorder (OUD) often experience infectious complications and challenges surrounding pain management, which contributes to high utilization of the health care system.1,2
Source: Annals of Allergy, Asthma and Immunology - December 30, 2020 Category: Allergy & Immunology Authors: Lily Li, Bianca Martin, Christin Price, Joji Suzuki, Tanya M. Laidlaw Tags: Letters Source Type: research
Reported drug allergies among patients with opioid use disorder: Role for allergy evaluation and intervention
Patients with opioid use disorder (OUD) commonly experience infectious complications and challenges surrounding pain management, which contribute to high utilization of the healthcare system.1,2
Source: Annals of Allergy, Asthma and Immunology - December 30, 2020 Category: Allergy & Immunology Authors: Lily Li, Bianca Martin, Christin Price, Joji Suzuki, Tanya M. Laidlaw Tags: Letters Source Type: research
Emergency Considerations in COVID-19 Vaccine Administration
Conclusion
The joint response of science and medicine to develop safe and effective COVID-19 vaccines has been brisk and productive. Distribution efforts will now be the next step in limiting the breadth of this pandemic. EMS agencies will play a key role in some areas in the administration of vaccinations for their communities.
The authors suggest that to better clarify the side effects of the COVID-19 vaccines, EMS systems must maintain a log of the type and incidence of adverse events following vaccine administration, EMS responses to the adverse events, as well as those patients’ outcomes from this management. ...
Source: JEMS Patient Care - December 16, 2020 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus Exclusives EMS EMT Paramedic Source Type: news
Comparison adductor canal block combined with local infiltration analgesia and adductor canal block alone for pain management after total knee arthroplasty: A randomized controlled trial protocol
Conclusion:
The study will provide more evidence on the combination use of adductor canal block and local infiltration analgesia in the treatment of pain after the total knee arthroplasty.
Trial registration:
This study protocol was registered in Research Registry (researchregistry5832).
Source: Medicine - August 28, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
