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Condition: Asthma
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Total 47890 results found since Jan 2013.
Chronic Diarrhea with Villous Blunting of the Small Intestine Under Capsule Endoscopy in Common Variable Immunodeficiency and X-Linked Agammaglobulinemia: A Case Series
Source: Journal of Asthma and Allergy - September 22, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Community and neighborhood level disparities in extreme climate exposure: implications for asthma and atopic disease outcomes
Source: Journal of Allergy and Clinical Immunology - September 22, 2023 Category: Allergy & Immunology Authors: Allison J. Burbank, Andre E. Espaillat, Michelle L. Hernandez Source Type: research
Nasal epithelial gene expression and total IgE in children and adolescents with asthma
Little is known about nasal epithelial gene expression and total IgE in youth.
Source: Journal of Allergy and Clinical Immunology - September 22, 2023 Category: Allergy & Immunology Authors: Zhongli Xu, Erick Forno, Yidan Sun, Michelle Manni, Yueh Ying Han, Soyeon Kim, Molin Yue, Judith M. Vonk, Elin T.M. Kersten, Edna Acosta-Perez, Glorisa Canino, Gerard H. Koppelman, Wei Chen, Juan C. Celed ón Source Type: research
Reply
We would like to express our gratitude to Chen and Yong1 for their interest in our article entitled “Human genetics influence microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment”.2 We read with enthusiasm their suggestions to increase the robustness of the genetic associations with microbiome composition that we reported in individuals from the Geno mics and Metagenomics of Asthma Severity (GEMAS) study.3
Source: Journal of Allergy and Clinical Immunology - September 22, 2023 Category: Allergy & Immunology Authors: Javier Perez-Garcia, Maria Pino-Yanes, Fabian Lorenzo-Diaz Tags: Correspondence Source Type: research
Inhaled corticosteroid treatment's impact on asthma exacerbations: Influence of human genetics on microbiome composition
We read with great interest the study by Perez-Garcia et al1 on the human genetics that influence microbiome composition involved in asthma exacerbations despite inhaled corticosteroid (ICS) treatment. In this retrospective cohort study using data from the Genomic and Metagenomics of Asthma Severity (GEMAS) study, Perez-Garcia et al1 hypothesized a rel ationship between the genetic variants, microbiome associated with asthma exacerbation, and possible biologic pathway. To augment their findings, we would like to offer several suggestions on covariates that could be adopted and included in their study.
Source: Journal of Allergy and Clinical Immunology - September 22, 2023 Category: Allergy & Immunology Authors: Yu-Jen Chen, Su-Boon Yong Tags: Correspondence Source Type: research
Shared decision making in food allergy: navigating an exciting era.
Shared decision-making is increasingly used in food allergy. We review its use in the areas of prevention, diagnosis and management.
Source: Annals of Allergy, Asthma and Immunology - September 22, 2023 Category: Allergy & Immunology Authors: Aikaterini Anagnostou Tags: CME Reviews Source Type: research
Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother-child cohort
CONCLUSION: Prenatal dietary exposure to chemicals was associated with risk of allergic rhinitis or wheezing up to age 8 y. A few chemicals were associated with other allergic and respiratory diseases. Larger prospective studies are needed to confirm these findings.PMID:37734145 | DOI:10.1016/j.envint.2023.108195
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Manel Ghozal Manik Kadawathagedara Rosalie Delvert Karine Adel-Patient Muriel Tafflet Isabella Annesi-Maesano Am élie Crépet V éronique Sirot Marie Aline Charles Barbara Heude Blandine de Lauzon-Guillain Source Type: research
Climate change is a health crisis with opportunities for healthcare action: A focus on healthcare providers, patients with asthma and allergic immune diseases, their families and neighbors
We present potential actions individuals can take at the family, neighborhood, community, healthcare system, national and international levels to build climate resilience, to protect their own health and the health and welfare of others.
Source: Journal of Allergy and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Nicholas J. Nassikas, Diane R. Gold Source Type: research
Eosinophilic bronchiectasis and therapeutic oportunities
Bronchiectasis is the third most frequent chronic inflammatory disease of the airways after chronic obstructive pulmonary disease (COPD) and asthma. Its diagnosis is established by clinical and radiological criteria based on the abnormal dilation of the bronchial lumen together with a clinical picture compatible with the inflammatory-infectious process causing the destruction of the bronchial wall and producing its dilation. This picture generally consists of a productive cough (often with a purulent component) and a variable number of exacerbations throughout the natural history of the disease 1.
Source: Annals of Allergy, Asthma and Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Grace Oscullo, Jose Daniel Gomez-Olivas, Miguel Ángel Martínez-García Tags: Editorial Source Type: research
Increasing wildfire smoke from the climate crisis: Impacts on asthma and allergies
Source: Journal of Allergy and Clinical Immunology - September 20, 2023 Category: Allergy & Immunology Authors: John R. Balmes, Stephanie M. Holm Source Type: research
The SARS-CoV-2 Pandemic and Asthma: What We Have Learned and What is still Unknown
The SARS-CoV-2 pandemic has brought new insights into the immunological intricacies of asthma. In this review, we discuss the epidemiology of asthma in patients infected with SARS-CoV-2 and the risk of severe infection. Type 2 inflammation had an overall protective effect against SARS-CoV-2 infection by various mechanisms summarized in this review. Asthma, intranasal, and inhaled corticosteroids decreased the ACE2 receptor, an important receptor for SARS-CoV-2 entry into host cells. We summarize the nuances of treatment of type 2 inflammation despite its underlying protective effects.
Source: Journal of Allergy and Clinical Immunology - September 20, 2023 Category: Allergy & Immunology Authors: Christa McPhee, Kateryna Yevdokimova, Linda Rogers, Monica Kraft Source Type: research
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
AbstractPurpose of ReviewImmunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention of IgE-mediated allergies and induction of immune tolerance. The present review addresses the role of IgA in the manifestation of IgE-mediated allergies, including allergen-specific immunotherapy (AIT), the regulation of IgA production, and the mechanism of IgA in immune cell activation.Recent FindingsThe majority of studies report an association of IgA with the induction of immune tolerance in IgE-mediated allergies. However, reports on the involvement of humoral and mucosal Ig...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research
Occupational Rhinitis: An Update
Discussion includes the impact of social trends on workers and the wider consequences of occupational rhinitis including decreased work productivity, absenteeism, and socioeconomic burden.SummaryOccupational rhinitis remains a challenging disease entity due to the numerous potential causative factors, reduced recognition, morbidity in asthma, and therapeutic limitations. Additional research is needed to better identify disease predictors and develop effective management strategies.
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research
Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
AbstractPurpose of ReviewThis review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in schools, examine the underlying mechanisms of these environmental risk factors, and explore possible prevention strategies.Recent FindingsCockroach, mouse, dust mites, fungi, viral infections, ozone pollution, and cleaning products are common allergen exposures and environmental risk factors in schools which may affect asthma morbidity. Novel modifiable environmental risk factors in schools are also being investigated to identify potential associations with increased asthma morbidity....
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research
Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
The objective of this study is to evaluate the effect of omalizumab as an adjunct to endoscopic sinus surgery (ESS) on the treatment of CRSwNP under real-life conditions.Recent FindingsSince the introduction of omalizumab, as the first biologic agent for the treatment of diseases such as severe allergic asthma, different studies have demonstrated an effect of omalizumab on CRSwNP, with significant improvements in sinonasal symptoms and endoscopic scores. The high efficacy derived from mAb therapy and the need for ESS prior to mAb recommended by guidelines, has led to compare both therapeutic alternatives, finding discrepan...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research
