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Condition: Asthma
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Total 47890 results found since Jan 2013.
Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR)
CONCLUSION: Tezepelumab reduced exacerbations across all seasons versus placebo in patients with severe, uncontrolled asthma, including patients with seasonal and perennial allergies. These data further support the efficacy of tezepelumab in a broad population of patients with severe, uncontrolled asthma.PMID:37619779 | DOI:10.1016/j.anai.2023.08.015
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Ian D Pavord Flavia C L Hoyte Andrew W Lindsley Christopher S Ambrose Joseph D Spahn Stephanie L Roseti Bill Cook Janet M Griffiths Åsa Hellqvist Nicole Martin Jean-Pierre Llanos Neil Martin Gene Colice Jonathan Corren Source Type: research
Population-Level Trends in Asthma and COPD Emergency Department Visits and Hospitalizations Before and During the COVID-19 Pandemic in the US
CONCLUSION: Onset of the COVID-19 pandemic coincided with reductions in acute care utilization for asthma and COPD. Understanding the mechanism of this reduction might inform future efforts to prevent exacerbations.PMID:37619778 | DOI:10.1016/j.anai.2023.08.016
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Adam Gaffney David U Himmelstein Steffie Woolhandler Source Type: research
How Does Global Warming Contribute to Disorders Originating from an Impaired Epithelial Barrier?
Ann Allergy Asthma Immunol. 2023 Aug 22:S1081-1206(23)00588-4. doi: 10.1016/j.anai.2023.08.010. Online ahead of print.ABSTRACTThe epithelial barrier represents the point of contact between the host and the external environment. It is the first line of defense against external insults in the skin, gastrointestinal and upper and lower respiratory tracts. The steep increase in chronic disorders in recent decades, including allergies and autoimmune disorders, has prompted studies to investigate the immune mechanisms of their underlying pathogeneses, all of which point to a thought-provoking shared finding: disrupted epithelial...
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Cevdet Ozdemir Umut Can Kucuksezer Ismail Ogulur Yagiz Pat Duygu Yazici Ioana Agache Marek Jutel Kari C Nadeau M übeccel Akdis Cezmi A Akdis Source Type: research
The US HAEA Scientific Registry: Hereditary Angioedema Demographics, Disease Severity, and Comorbidities
CONCLUSION: The US HAEA Scientific Registry provides a mechanism to enhance our knowledge of HAE and INHA.PMID:37619776 | DOI:10.1016/j.anai.2023.08.012
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Sandra C Christiansen Joyce Wilmot Anthony J Castaldo Bruce L Zuraw US HAEA Medical Advisory Board members Source Type: research
When Nutrition Trends and Food Allergies Collide
Ann Allergy Asthma Immunol. 2023 Aug 22:S1081-1206(23)00592-6. doi: 10.1016/j.anai.2023.08.014. Online ahead of print.NO ABSTRACTPMID:37619775 | DOI:10.1016/j.anai.2023.08.014
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Marion Groetch Isabel Skypala Source Type: research
Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR)
CONCLUSION: Tezepelumab reduced exacerbations across all seasons versus placebo in patients with severe, uncontrolled asthma, including patients with seasonal and perennial allergies. These data further support the efficacy of tezepelumab in a broad population of patients with severe, uncontrolled asthma.PMID:37619779 | DOI:10.1016/j.anai.2023.08.015
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Ian D Pavord Flavia C L Hoyte Andrew W Lindsley Christopher S Ambrose Joseph D Spahn Stephanie L Roseti Bill Cook Janet M Griffiths Åsa Hellqvist Nicole Martin Jean-Pierre Llanos Neil Martin Gene Colice Jonathan Corren Source Type: research
Population-Level Trends in Asthma and COPD Emergency Department Visits and Hospitalizations Before and During the COVID-19 Pandemic in the US
CONCLUSION: Onset of the COVID-19 pandemic coincided with reductions in acute care utilization for asthma and COPD. Understanding the mechanism of this reduction might inform future efforts to prevent exacerbations.PMID:37619778 | DOI:10.1016/j.anai.2023.08.016
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Adam Gaffney David U Himmelstein Steffie Woolhandler Source Type: research
How Does Global Warming Contribute to Disorders Originating from an Impaired Epithelial Barrier?
Ann Allergy Asthma Immunol. 2023 Aug 22:S1081-1206(23)00588-4. doi: 10.1016/j.anai.2023.08.010. Online ahead of print.ABSTRACTThe epithelial barrier represents the point of contact between the host and the external environment. It is the first line of defense against external insults in the skin, gastrointestinal and upper and lower respiratory tracts. The steep increase in chronic disorders in recent decades, including allergies and autoimmune disorders, has prompted studies to investigate the immune mechanisms of their underlying pathogeneses, all of which point to a thought-provoking shared finding: disrupted epithelial...
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Cevdet Ozdemir Umut Can Kucuksezer Ismail Ogulur Yagiz Pat Duygu Yazici Ioana Agache Marek Jutel Kari C Nadeau M übeccel Akdis Cezmi A Akdis Source Type: research
The US HAEA Scientific Registry: Hereditary Angioedema Demographics, Disease Severity, and Comorbidities
CONCLUSION: The US HAEA Scientific Registry provides a mechanism to enhance our knowledge of HAE and INHA.PMID:37619776 | DOI:10.1016/j.anai.2023.08.012
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Sandra C Christiansen Joyce Wilmot Anthony J Castaldo Bruce L Zuraw US HAEA Medical Advisory Board members Source Type: research
When Nutrition Trends and Food Allergies Collide
Ann Allergy Asthma Immunol. 2023 Aug 22:S1081-1206(23)00592-6. doi: 10.1016/j.anai.2023.08.014. Online ahead of print.NO ABSTRACTPMID:37619775 | DOI:10.1016/j.anai.2023.08.014
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Marion Groetch Isabel Skypala Source Type: research
“Vegan” and “plant-based” claims: risk implications for milk- and egg-allergic consumers in Canada
The market share of foods carrying labels suggesting absence of animal ingredients has significantly increased in recent years. The purpose of this study was to document the purchasing behaviour of egg- or mil...
Source: Allergy, Asthma and Clinical Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Silvia Dominguez, J érémie Théolier, Kamila Lizée, Beatrice Povolo, Jennifer Gerdts and Samuel B. Godefroy Tags: Short report Source Type: research
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
AbstractPurpose of ReviewImmunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention of IgE-mediated allergies and induction of immune tolerance. The present review addresses the role of IgA in the manifestation of IgE-mediated allergies, including allergen-specific immunotherapy (AIT), the regulation of IgA production, and the mechanism of IgA in immune cell activation.Recent FindingsThe majority of studies report an association of IgA with the induction of immune tolerance in IgE-mediated allergies. However, reports on the involvement of humoral and mucosal Ig...
Source: Current Allergy and Asthma Reports - August 23, 2023 Category: Allergy & Immunology Source Type: research
Prevalence and Burden of Coconut Allergy in the United States
Epidemiological data about coconut allergy remains sparse in the United States (US) despite the Food Allergen Labeling and Consumer Protection Act's labeling requirement for products containing coconut.
Source: Annals of Allergy, Asthma and Immunology - August 23, 2023 Category: Allergy & Immunology Authors: Christopher M. Warren, Shruti Sehgal, Sai R. Nimmagadda, Ruchi Gupta Source Type: research
Adding oscillometry to spirometry in guidelines better identifies uncontrolled asthma, future exacerbations, potential targeted therapy
The objective of this review is to provide new advances in our understanding of the clinical importance of establishing peripheral airway impairment (PAI) by impulse oscillometry (IOS), and targeted therapy, which could result in better asthma outcomes.Data sources include Pub Med and Google search, limited to English language and human disease, with key words IOS and asthma.Key findings: Using IOS reference equations, PAI is consistently associated with uncontrolled asthma across ethnicity, using Hispanic and White reference algorithms.
Source: Annals of Allergy, Asthma and Immunology - August 23, 2023 Category: Allergy & Immunology Authors: Stanley P. Galant, Tricia Morphew Tags: Review Source Type: research
The lung-gut crosstalk in respiratory and inflammatory bowel disease
Both lung and gut belong to the common mucosal immune system (CMIS), with huge surface areas exposed to the external environment. They are the main defense organs against the invasion of pathogens and play a key role in innate and adaptive immunity. Recently, more and more evidence showed that stimulation of one organ can affect the other, as exemplified by intestinal complications during respiratory disease and vice versa, which is called lung-gut crosstalk. Intestinal microbiota plays an important role in respiratory and intestinal diseases. It is known that intestinal microbial imbalance is related to inflammatory bowel...
Source: Frontiers in cellular and infection microbiology - August 23, 2023 Category: Microbiology Source Type: research
